Intinol forto for mastopathy is used to gently correct the level of estrogen in a woman’s body. The drug not only reduces the intensity of pain, but also helps to reduce the size of the seals.
This is possible due to the effect on the mechanism of disease development. Indinol forte is one of the most effective and at the same time safe drugs for the treatment of mastopathy. Side effects and complications develop extremely rarely.
When is the drug prescribed?
Indinol forte is a dietary supplement. It cannot be used uncontrolled, but only after a complete examination of the woman, as prescribed by a gynecologist or oncologist. The drug is prescribed in the following cases:
- abnormally rapid growth of breast tissue, in which there are no signs of malignancy (mastopathy);
- chest pain resulting from mastopathy;
- as a component of complex therapy for certain diseases of the uterus, in the absence of manifestations of malignancy (endometriosis, fibroids, endometrial hyperplasia, etc.);
- dysplasia or pathological changes in cervical cells, formation of condylomas in the anogenital area caused by HPV.
In addition, the list includes the prevention of the development of not only mastopathy, but also other functional diseases of the mammary glands. Prevention of relapse of endometriosis, adenomyosis, uterine fibroids, endometrial hyperplasia after surgery.
Composition and principle of action
The main active ingredient of Indinol Forto is indole carbinol. Additional components in the drug include corn starch, microcrystalline cellulose, magnesium stearate and lactose monohydrate. The dietary supplement is available in capsules with a dosage of 200 mg. One package contains 60, 90 or 120 capsules.
The principle of action of the drug lies in the antiestrogenic and antiproliferative properties of indolecarbinol. Thanks to this, the medicine stops the rapid growth of cells and prevents the progression of hyperplastic processes.
Capable of selectively acting on cells in the mammary glands that exhibit high activity. Leads to their death and prevents their rapid growth and proliferation. Indolecarbinol blocks estrogen-dependent cell stimulation and prevents the activation of other mechanisms responsible for the rapid growth of pathological cells.
Prevents the proliferation of blood vessels and the formation of venous networks. Prevents the development of neoplasms in breast tissue.
Indinol forte should be stored in a dry place, protected from sunlight. Out of reach of children and animals. The shelf life is indicated on the packaging and should not exceed 3 years.
How to take for mastopathy
A course of treatment with Indinol Forte can only be prescribed by a doctor - depending on the characteristics of the course of the disease and its type (fibrous, cystic, mixed - fibrocystic). The standard daily dosage is 400 mg (2 capsules).
For fibrocystic mastopathy, Indinol Forte is used 2 capsules per day with meals. The duration of treatment ranges from 2 to 6 months. The effectiveness of the therapy lasts up to 2-3 months. If necessary, the doctor can decide whether a second course of treatment is advisable.
In the treatment of hyperplastic processes in the uterus, which include adenomyosis, endometriosis, etc., Indinol forte is recommended to be taken in parallel with another dietary supplement - Epigallate. Recommended dosage – 1-2 tablets 1 time per day.
For infections of the reproductive system caused by the human papillomavirus, Indinol form is used as an addition to antiviral therapy (1 capsule once a day for 3–4 weeks).
This allows you to enhance the medicinal effect of the drugs and speed up the patient’s recovery.
Indolecarbinol is prescribed with caution to patients who constantly use indirect anticoagulants, hormonal agents, oral contraceptives, as well as antiepileptic, hypoglycemic, and antiarrhythmic drugs. It can weaken or enhance their effect, so dosage adjustment is required to prevent progression of the underlying disease and deterioration of the woman’s well-being.
The drug is able to increase the effectiveness of antibacterial drugs included in the group of tetracyclines and beta-lactamases. Increases the sensitivity of certain types of microorganisms to the action of antimicrobial agents.
Shows antioxidant properties. Protects cell membranes from the damaging effects of free radicals, toxins, and allergens. Helps neutralize them and remove them out.
Contraindications
The following contraindications to the use of Indinol Forte are identified. They should be taken into account before prescribing the drug in order to avoid the development of adverse reactions and complications. These include:
- an allergic reaction to one or more components present in the drug;
- hereditary diseases of the gastrointestinal tract, in which galactose intolerance, lactase deficiency, etc. are observed;
- period of pregnancy and lactation;
- The medicine should not be used in children and adolescents; there is no data on the safety of use in patients of this age.
Side effects
The use of Indinol forte may provoke the development of adverse reactions. Most often, disturbances of the ovarian-menstrual cycle occur. Its duration becomes much longer or, conversely, shorter. Menstruation becomes irregular.
Other reactions:
- discomfort and heaviness in the stomach;
- weight loss;
- violation of the leukocyte formula - the appearance of a large number of eosinophils in the peripheral blood;
- increased levels of thyroid-stimulating, follicle-stimulating and other hormones;
- impaired renal excretory function (decreased creatinine levels in the blood).
Side effects after taking Indinol Forte are mild. When the drug is discontinued, all symptoms go away on their own. The woman's condition does not require medical intervention.
In rare cases, these symptoms may intensify. In this case, it is necessary to consult with a specialist to adjust the dosage and decide on the advisability of further use of Indinol Forte. If necessary, the doctor will prescribe another drug to treat the disease.
If the recommended dosage is exceeded, complications may develop. These include nausea, vomiting, and stool upset. To relieve symptoms, symptomatic therapy is used; there is no specific antidote.
The medicine does not affect the ability to drive vehicles. During treatment, a woman can drive a car and be involved in work that requires high-precision reactions.
Reviews from doctors
I often use Indinol Forte in my practice. The drug has proven to be an effective remedy in the treatment of mastopathy. There are practically no side reactions. The exception is when a woman independently exceeds the prescribed dosage.
Victoria Vasilievna, gynecologist
Indinol forte is a natural drug that normalizes the level of estrogen in the blood. It has a large number of advantages over other drugs for the treatment of all forms of mastopathy, as well as cyclic mastalgia. Does not lead to weight gain, which is extremely important for many women.
Irina Aleksandrovna, gynecologist
Mastopathy is a serious disease that requires long-term treatment. The optimal drug for treating the problem is Indinol forte. It is effective for all forms of the disease - fibrocystic and glandular. The main condition for successful use is long-term use, at least 3-6 months.
Miroslava Stepanovna, gynecologist
Reviews
As prescribed by the doctor, I have been using Indinol forte for 3 months. I didn’t expect a miracle from him, since I tried a lot of drugs for fibrocystic mastopathy. However, the positive effect appeared after 4 weeks of regular use. The breasts became less painful, the lumps seemed to soften. I hope that over time they will completely disappear.
Anastasia, 44 years old, Chelyabinsk
I can’t say that Indinol Forte helped get rid of mastopathy, but the condition has improved a lot. The painful sensations that haunted me on the eve of my period disappeared. The doctor recommended taking the drug for another 3 months, after which you need to take a break.
Alina, 35 years old, Yalta
Indinol forte is an excellent drug. I have been using this course for the second year in a row (with interruptions). Based on the results of the last examination, the doctor said that the lumps in the chest had become much smaller. One more course and you can finish the treatment.
Polina, 38 years old, Nizhny Novgorod
Source: https://mammolog.guru/zabolevaniya-grudi/mastopatiya/indinol-forto.html
Indinol for mastopathy
Indinol is a biologically active food additive (BAA). The action of the drug is aimed at suppressing the growth of hormone-dependent tumors. The drug is recommended as part of complex therapy for various benign tumors of the reproductive organs and mastopathy in women.
Indinol is a herbal remedy. The main active ingredient is indole-3 carbinol. This component is isolated from plants of the cruciferous family. The raw materials for the production of dietary supplements are broccoli, radishes, turnips, cabbage and other members of the family. Auxiliary and formative substances in the composition:
- lactose monohydrate;
- starch
- magnesium stearate;
- microcrystalline cellulose.
The release form of the medicine is capsules. The product is packaged in blisters of 10 pieces (3 blisters in a cardboard package), or in polymer jars of 60 or 120 capsules. Regardless of the release form, each capsule contains 100 mg of indole-3 carbinol.
Pharmacological action and features of the drug
Hormone-dependent tumors, cysts and fibrous growths in the mammary glands are the result of the influence of estrogen. The main line of action of Indinol is anti-estrogenic activity aimed at normalizing the balance of this hormone. Taking Indinol blocks the negative stimulating effect of estrogen, thereby reducing the rate of progression of tumor and cystic processes in the female body.
Indole-3 carbinol additionally affects non-hormonal mechanisms that affect the pathological proliferation of cells in the mammary glands and uterus. Despite the specificity of the action, Indinol is not a hormonal drug.
Main properties of the medicine:
- antiestrogenic activity;
- normalization of estrogen metabolism;
- decreased sensitivity of estrogen receptors in target organ tissues.
The drug is used for the treatment and prevention of epithelial tumors of the female reproductive system.
Under the influence of estrogens, primarily estradiol, proliferation of tissue cells of the mammary glands, ovaries, and uterus occurs.
Indinol acts indiscriminately, stopping the pathological process of proliferation of all tissues sensitive to estrogen.
Thus, the drug blocks tumor processes in all cells prone to proliferation, not only stopping the growth of the tumor, but also causing the death of the changed cells.
A few facts about the drug:
- is not a medicine, but belongs to dietary supplements;
- does not contain hormones;
- does not cause side effects.
At the same time, Indinol is ineffective as an independent remedy for the treatment of various diseases, and is prescribed only as part of complex drug therapy.
Indications for use
Capsules are prescribed as an adjuvant for the treatment of diseases of the reproductive system caused by the proliferation of epithelial cells. Indications for use:
- fibrocystic mastopathy;
- endometriosis;
- cystic formations of the ovaries;
- fibroids and uterine fibroids;
- cervical dysplasia.
The dietary supplement is used in the complex treatment of papillomatosis. The drug is prescribed after removal of papillomas on the genitals to prevent their re-formation.
As a prophylactic agent, Indinol can be used after treatment of uterine or breast cancer. In this case, the decision about the advisability of taking capsules should be made by a doctor.
The dietary supplement is practically safe, non-toxic and does not cause side effects, so it can be used by women at risk to prevent the development of hormone-dependent tumors.
In the treatment of HPV, Indinol is prescribed after surgical removal of growths, together with immunomodulatory drugs.
In the photo Indinol Forto
Mastopathy is the result of hormonal imbalance and inflammatory processes in the tissues of the mammary gland. The disease is characterized by the formation of small nodular seals. Mastopathy develops slowly.
At a young age, there are minor pains before menstruation, which practically do not bother the woman. Over time, the pain intensifies and becomes a permanent symptom.
Mastopathy, as a rule, begins to worry after childbirth, during breastfeeding, or when hormonal levels change in women over 40 years of age.
With mastopathy, breast tissue grows, which increases the risk of developing cancer . Examination of patients with mastopathy reveals increased levels of estrogen. The disease must be treated; the lumps themselves do not resolve.
Indinol for mastopathy is a safe means for controlling estrogen levels. The dietary supplement not only reduces estrogen levels, but also affects already changed cells, causing their death. This explains the decrease in mammary gland hyperplasia when taking Indinol capsules.
As an independent remedy, Indinol can be taken for mild fibrocystic mastopathy. The medicine reduces hyperplasia, eliminates pain and stops the progression of the disease. Due to its pronounced antioxidant and oncoprotective properties, Indinol significantly reduces the risk of developing breast cancer in women prone to mastopathy.
In severe forms of the disease, dietary supplements are prescribed as an adjuvant as part of complex therapy. The choice of the main line of drug treatment in this case should be made only by a doctor.
Indinol can be taken for preventive purposes, to reduce the risk of developing mastopathy and tumor pathologies of the female reproductive system.
Indinol or Indole forte: comparison of drugs
Indole forte is a potent analogue of the drug Indinol. These dietary supplements differ in the concentration of the active substance and formative components. Indole forte contains:
- 100 mg indole-3 carbinol;
- 92.5 mg natural broccoli;
- cellulose;
- calcium stearate;
- aerosil.
Indole forte is available in capsules. They are packed in blisters of 15 pieces, in a package there are 2 or 4 blisters.
The products are analogues and have the same indications and contraindications. Indinol is recommended as a dietary supplement to food in the early stages of mastopathy; Indole forte is often prescribed as part of complex therapy for severe forms of the disease.
Both drugs are classified as dietary supplements and are not medicines.
How to take the drug?
Indinol is taken one capsule twice a day. It is recommended to drink capsules before or during meals - this will reduce the risk of negative effects on the gastrointestinal tract and speed up the absorption of the drug. The course of treatment is long - from three months to six months.
What causes pain in the mammary gland
To prevent mastopathy, capsules are taken daily for 3 months. In severe cases of the disease, the duration of use increases to 6 months, and on the recommendation of a doctor, the dosage can be doubled.
If it is necessary to take large doses of medication, preference is given to Indole Forte capsules, as they contain a large amount of broccoli extract. This drug is taken 1 capsule per day for 3-6 months. For severe forms of mastopathy, the dosage is doubled.
Contraindications
There are few absolute contraindications to the use of dietary supplements. These include:
- individual intolerance to indinol-3 carbinol or formative substances in the capsules;
- period of bearing a child;
- lactation;
- childhood and adolescence.
No studies have been conducted on the effect of the drug on the body of children, therefore the dietary supplement is not prescribed to persons under 18 years of age.
For diseases of the liver and kidneys, taking the medicine is not prohibited, since indole-3 carbinol does not have a toxic effect on the body and does not affect the functioning of these organs.
The drug is not recommended for use in case of acid-dependent gastric pathologies that require constant use of antacid medications. Medicines that reduce gastric acidity interfere with the absorption of Indinol.
Side effects
Indinol and Indol Forte are well tolerated by the body and do not cause side effects, with rare exceptions. In cases of individual intolerance to the main active ingredient or auxiliary formative components, symptoms of an allergic reaction may appear:
- itchy skin rash;
- tearfulness;
- nasal congestion;
- frequent sneezing.
Source: https://www.mammologia.ru/zabolevanija/mastopatiya/indinol-pri-mastopatii/
Indole for mastopathy: will tablets help, how to take the medicine (Indole and Indole Forte), treatment for fibrocystic mastopathy
Indinol is capable of indiscriminately correcting pathological hypertrophic processes in the tissues and organs of the female reproductive system (breasts, uterus, ovaries, etc.).
Indinol is nonspecific and acts on various cells of the body that have changed as a result of exposure to different types of estrogen
The word "non-selective" means that it works anywhere there is cell proliferation due to high estrogen levels. The key property of the drug is the ability to cause the death of altered cells with an increased tendency to proliferation.
Mastopathy is a process in which individual cells begin to grow pathologically in a woman’s mammary gland. Most often this is due to a hormonal factor or inflammatory pathology in this area.
In most cases, the disease does not bother the woman in the initial stages, but later it manifests itself as focal lumps and pain in the chest area.
Pain in the mammary glands indicates mastopathy that has been developing for quite some time.
The key danger of mastopathy is the possibility of degeneration into a malignant neoplasm. During the examination period, many women are found to have an increased level of estrogen in the blood, so many treatment agents have an anti-estrogenic effect.
In case of mastopathy, Indinol exhibits antiestrogenic properties and causes the death of existing pathologically hypertrophied cells.
Indolecarbinol, which is part of the drug, blocks estrogen receptors, thereby reducing their synthesis in the patient’s body. In addition, it destroys pathologically overgrown cells.
To achieve the effect, you should take dietary supplements for at least 2–3 months.
Mammologists recommend their patients a long course of treatment with the drug
In what cases is it prescribed?
The medicine is prescribed in conjunction with other treatment methods for various diseases of the reproductive system, in which processes of cell proliferation are observed. Can be used as a means of preventing hormone-dependent pathologies. Indinol can also be used for the following diagnoses:
- Different forms of mastopathy. Prescribed for the prevention of fibrocystic mastopathy in combination with other treatment methods and together with other medications;
- Endometriosis. It is used for proliferative processes in the uterus, as well as for the prevention of relapses in the postoperative period.
- Myoma or fibroids of the uterus, ovarian cysts.
- Malignant neoplasms of the ovaries, mammary glands and uterus after consultation with the treating doctor.
Indinol can be prescribed as an adjuvant for oncopathologies of the female genital organs
- Dysplastic processes on the cervix.
- Human papillomavirus infection and its manifestations (condylomas acuminata, papillomas, etc.).
The drug is a relatively non-toxic drug, so it is well tolerated by patients with other concomitant diseases.
The medications that a specialist prescribes for this disease affect not only the mammary glands, but also help eliminate the very cause of the disease.
For example, if a woman has hormonal imbalance, she is recommended to use hormonal drugs. When severe swelling of the breast appears as a result of the disease, diuretics cannot be avoided.
During the treatment of mastopathy, sedatives are used, since in addition to pain, a woman may be irritable and agitated.
Adaptogenic drugs affect the entire body, improving its functioning and setting it up for recovery. Also used for the treatment of fibrocystic mastopathy:
- herbal medicine.
- Homeopathy.
- Local treatment (ointment, compress, gel).
IMPORTANT. Medicines and duration of treatment are prescribed only by a specialist, and only after a full examination has been carried out. Self-indulgence can significantly aggravate the situation.
Interaction with other agents and analogues
The drug selectively affects the activity of the cytochrome P450 enzyme. Given this fact, it is prescribed with caution to patients who take medications involved in its processing, namely indirect anticoagulants, drugs for epilepsy, hormones, etc.
What drugs can replace Indinol? Indinol Forto and Intrinol will have a similar effect. If necessary, you can combine Indinol and Epigallate.
Epigallate is also available separately from Indinol, but it is recommended to take them together
If this nutritional supplement is not suitable for the patient, then other remedies with a similar effect can be chosen to treat mastopathy:
- Mastodinon. Homeopathic remedy in drops and tablets for the treatment of diseases of the female reproductive system. It is an alcohol solution of a complex of medicinal herbs. Normalizes hormonal balance and promotes resorption of mastopathy foci. Used as a course for six months. A contraindication for use is an allergy or intolerance to the natural components included in its composition.
- Progestogel. Local gel based on the hormone progesterone. This remedy locally blocks estrogen receptors and reduces swelling and tenderness of the mammary glands. Since this is a local form, systemic effects on the body are unlikely.
- Bromocriptine. A dopamine receptor stimulator, which is used in the practice of gynecologists.
You can replace Indinol with Bromocriptine or other drugs only in consultation with your doctor.
- Cyclodinone. Tablets and drops of plant origin that have a normalizing effect on the hormonal balance in a woman’s body. The drug is used in the treatment of disorders of female reproductive function. Cyclodinone is well tolerated by patients, but in rare cases it can cause allergies.
There is no universal approach to the treatment of mastopathy. One patient will be helped by Indinol in combination with other dietary supplements and diet, while another woman will get rid of the problem only with the help of hormonal agents. The selection of medications should be carried out by the attending physician, who can monitor the dynamics of the development of mastopathy foci and promptly adjust or change the treatment.
The parallel use of capsules of this dietary supplement and medications that reduce gastric acidity is not recommended.
Of course, today you can buy analogues in pharmacies that are cheaper than Indinol, but when choosing such drugs, you should first of all take into account the effectiveness of the product being purchased, as well as the number of therapeutic units in the package (tablets, capsules). Thus, it is best to leave the determination of a possible replacement for this dietary supplement at the discretion of a doctor or qualified pharmacist.
Although these two drugs are indicated for use in mastopathy of fibrocystic etiology and are quite often included in the treatment regimens of some doctors, they are completely different in composition and belong to different pharmacological groups.
Both the dietary supplement Indinol and the homeopathic remedy Mastodinon for mastopathy may be quite effective or, on the contrary, may not be suitable for a certain patient.
In this case, one should rely on the experience and qualifications of the attending physician and the response of the patient’s body to the treatment.
The question of what is the difference between Indinol and Indinol Forto, or what is the difference between these two products from the same manufacturer, JSC MiraxBioPharma, often arises in various forums devoted to the problem of treating neoplasms of the female reproductive system.
Both of these drugs include a similar active ingredient - indole-3-carbinol, which naturally unites them in terms of application, side effects, contraindications and other parameters, but they belong to different pharmacological groups.
The main difference between these drugs is that Indinol, which, by the way, is the predecessor of Indinol Forto, belongs to dietary supplements, while Indinol Forto is already a full-fledged drug with a better purified active ingredient, which is found in the drug in a higher dosage (200 mg) , which makes it easier to take and increases the effectiveness of treatment. In clinical practice, both of these drugs have proven themselves to be positive and therefore still remain quite competitive.
Pharmacodynamics and pharmacokinetics
Indinol is a dietary supplement (dietary supplement) of plant origin with antitumor and antiestrogenic activity, the main ingredient of which exhibits the properties of a universal corrector of hyperplastic pathological processes occurring in the tissues and organs of the female reproductive system (including the cervix, mammary gland, ovaries, myometrial and endometrial tissue).
Taking capsules of the drug helps normalize the estrogen balance in the female body, inhibits the negative stimulating effects of estrogens, and also acts as a blocker of other mechanisms (hormone-independent), which are activators of pathological cell growth in the uterine tissues and breast tissues. In addition, this dietary supplement is selectively capable of causing pathologically transformed cells, characterized by high abnormal proliferative activity, to death.
The effectiveness of Indinol is observed in therapy aimed at suppressing the growth of epithelial tumors of the female reproductive system, including estrogen-dependent formations.
The positive effect of the drug is observed when it is used against negative hyperplastic processes occurring in the female reproductive organs, which occur when there is a violation of the regulation of cell division.
Also, taking the drug is quite productive in the treatment of infectious pathologies associated with human papillomavirus. In this case, the action of the dietary supplement is aimed at blocking the synthesis of the E7 oncoprotein in papillomavirus-infected epithelial cells, which leads to inhibition of the processes of malignancy.
Indinol, instructions for use
Instructions for use of Indinol recommend that women with diagnosed mastopathy of fibrocystic etiology take 1 capsule of the drug orally every 24 hours with meals for 2-3 weeks.
Instructions for use of Indinol Epigallate (including separately purchased drugs or a specially produced set of Indinol Epigallate capsules) recommends the use of this combination of dietary supplements in the combined treatment of endometrial hyperplasia (passing without atypia), adenomyosis (a type of endometriosis) and uterine fibroids. This therapy is carried out with a single dose per day of 1-2 capsules of each drug with meals for at least 2-3 weeks and up to 6 months.
For genital pathologies caused by human papillomavirus, Indinol is prescribed orally, 1 capsule once every 24 hours, in combination with therapeutic agents - immunomodulators, which are advisable to use as standard therapy for such diseases. In this case, the patient’s sexual partner must undergo a similar therapeutic course.
It should be remembered that it is prohibited to prescribe Indinol yourself; before taking this dietary supplement, the patient must consult with his or her doctor.
Reviews from women
Evaluation of a drug or treatment
Source: https://sustavrip.ru/osteoxondroz/prinimat-lekarstva-mastopatii-klamin-indinol-forte-aevit-vobenzim-indol-forte.html
How to take Indinol for mastopathy
An important factor in the treatment of fibrocystic disease is the restoration of hormonal balance with the normalization of the menstrual cycle.
The drug Indinol for mastopathy is used for preventive and therapeutic purposes, providing a multifaceted effect on the mammary gland and reproductive organs of a woman.
The optimal therapeutic result will be with strict adherence to the recommended dosage of the drug and duration of treatment.
Non-hormonal drug
Against the background of benign breast pathology, almost every woman has an endocrine disorder associated with the functioning of the ovaries and manifests itself as a violation of menstruation.
It is not always possible to use hormonal drugs for treatment: the doctor can prescribe a non-hormonal drug with a good effect on the uterine appendages.
Indinol Forto for diffuse mastopathy provides the following effects:
- elimination of premenstrual tension in the mammary glands;
- relief from pain associated with mastalgia;
- reducing the severity of structural abnormalities in the breast (elimination of heaviness and compaction in the mammary gland tissue);
- reducing the risk of cyst formation;
- significant reduction in the risk of breast cancer.
The basis of endocrine disorders in any form of mastopathy is hyperestrogenism (an increase in the amount of estrogen hormones in the blood), which leads to proliferative changes in tissues. As doctors' reviews show, Indinol Forto for mastopathy has the following targeted effect on breast tissue:
- prevention of high proliferative activity of cells caused by hyperestrogenic influences;
- stimulates selective death of cellular structures with an increased tendency to hyperplasia and proliferation;
- provides genetically determined production of an antitumor protein that helps prevent malignant degeneration in the breast.
The drug acts on cells with high proliferative activity in different tissues of the woman’s reproductive system (endometrium, cervix, myometrium), which provides a variety of positive effects of the drug in concomitant gynecological pathologies.
Useful properties of the drug
In complex therapy of benign diseases of the female organs, it is important to create the maximum therapeutic effect using a minimum amount of drugs. The most important positive properties of Indinol include:
- antiproliferative;
- anti-inflammatory;
- antiestrogenic;
- antivascular;
- antioxidant.
Factors of the drug can and should be used for the treatment of combined pathology of the breast and uterus. When a doctor identifies a myomatous node, polyp or endometrial hyperplasia against the background of mastopathy, taking Indinol Forto tablets would be a good option for complex therapy.
Indications for therapy
A non-hormonal drug is used for the following diseases:
- mastalgia associated with the menstrual cycle;
- diffuse mastopathy with a predominance of the glandular component;
- glandular cystic mastopathy;
- combined forms of gynecological pathology
.
It is necessary to strictly follow the doctor's recommendations, taking the drug only as indicated and in the prescribed doses. An important criterion is age: it is advisable to treat with Indinol from 20 to 45 years of age.
Contraindications for use
It is unacceptable to use therapy against the background of the following diseases and conditions:
- pregnancy and lactation;
- malignant tumors;
- acute inflammation in the mammary gland (mastitis);
- diseases of the thyroid gland (hyperthyroidism, hypothyroidism);
- high levels of prolactin in the blood (hyperprolactinemia);
- childhood;
- allergic reactions or intolerance to the drug.
Indinol Forto tablets are a non-toxic and safe drug, but in some situations side effects are possible:
- cycle disruption in the form of shortening or lengthening of critical days;
- hormonal changes in the endocrine system (thyroid gland, pituitary gland);
- pain in the abdomen;
- unexplained weight loss.
Side effects are rare: every woman taking Indinol tablets should immediately contact a specialist if complaints arise.
Course regimen of therapy
The standard and most effective method of therapy is six-monthly intake of tablets at a dose of 400 mg per day. The doctor can prescribe a treatment regimen individually, but in any case the tablet should be taken before meals.
Efficacy of therapy
After a 6-month course of treatment, the doctor will conduct a comprehensive examination, including the following studies:
- palpation examination of the breast;
- ultrasound scanning;
- mammography.
In addition to improving the quality of life of a woman and the disappearance of unpleasant complaints, the main criteria for successful treatment are:
- reducing the number and size of cystic cavities in the breast;
- disappearance of dilated milk ducts;
- improved tissue homogeneity with reduced echo density.
Reviews from doctors indicate the positive effect of a long course of treatment with Indinol Forto tablets. Most women tolerate the drug well, but if there are contraindications or if side effects occur, you should immediately consult a doctor.
Source: https://gynecologyhelp.ru/mastopatiya/indinol-forto.html
Indinol
The composition of the drug as an active ingredient includes indole-3-carbinol in a mass part of at least 90 mg in 1 capsule, contained in 100 mg of extract isolated from the cruciferous plant family.
Additionally, this dietary supplement contains: 3 mg of magnesium stearate, 27 mg of microcrystalline cellulose, 80 mg of starch and 90 mg of lactose.
Release form
The biological additive Indinol is produced in the form of capsules of 60 or 120 pieces per package (polymer jar in a cardboard box).
pharmachologic effect
Correcting hyperplastic pathological processes occurring in the tissues and organs of the woman’s reproductive system.
Pharmacodynamics and pharmacokinetics
Indinol is a dietary supplement ( dietary supplement ) of plant origin with antitumor and antiestrogenic activity, the main ingredient of which exhibits the properties of a universal corrector of hyperplastic pathological processes occurring in the tissues and organs of the female reproductive system (including the cervix , mammary gland, ovaries, myometrial and endometrial ). Taking capsules of the drug helps normalize the estrogen balance in the female body, inhibits the negative stimulating effects of estrogens , and also acts as a blocker of other mechanisms ( hormone -independent), which are activators of pathological cell growth in the uterine tissues and breast tissues. In addition, this dietary supplement is selectively capable of causing pathologically transformed cells, characterized by high abnormal proliferative activity , to death.
The effectiveness of Indinol is noted in therapy aimed at suppressing the growth of epithelial tumors of the female reproductive system, including estrogen-dependent formations .
The positive effect of the drug is observed when it is used against negative hyperplastic processes occurring in the female reproductive organs, which occur when there is a violation of the regulation of cell division.
The effects of the active ingredient of this dietary supplement significantly inhibit or completely neutralize growth factors that stimulate the formation of tumors in the mammary glands.
Also, taking the drug is quite productive in the treatment of infectious pathologies associated with human papillomavirus . In this case, the action of the dietary supplement is aimed at blocking of the E7 oncoprotein epithelial cells with papillomavirus , which leads to inhibition of the processes of malignancy.
Indications for use
As a dietary supplement, Indinol is recommended for use as an additional source of the substance - indole-3-carbinol .
As a remedy with medicinal properties, Indinol is indicated for use in:
- carrying out the prevention or complex therapy of mastopathy of fibrocystic etiology, as well as for the purpose of correcting the functional state of the female mammary glands, in which changes have occurred due to the development of this pathology;
- of Epigallat dietary supplement capsules as part of a therapeutic complex treatment of endometrial hyperplasia (passing without atypia), adenomyosis (a type of endometriosis ), uterine fibroids , as well as for the prevention of these pathologies after surgery;
- carrying out complex therapy for diseases of the female genital area associated with human papillomavirus , including anogenital condylomatosis and cervical dysplasia (cervical intraepithelial neoplasia).
Contraindications
Contraindications to taking Indinol are:
- personal hypersensitivity of the patient to indole-3-carbinol or other components of the capsules;
- breastfeeding and pregnancy ;
- carrying out therapy with the use of medications that reduce gastric acidity .
Side effects
The results of preclinical and clinical studies of Indinol showed that this dietary supplement was well tolerated by patients and the absence of any side effects when taken in therapeutic doses.
Indinol, instructions for use
Instructions for use of Indinol recommend that women with diagnosed mastopathy of fibrocystic etiology take 1 capsule of the drug orally every 24 hours with meals for 2-3 weeks.
Instructions for use Indinol + Epigallate (including separately purchased drugs or a specially produced set of capsules Indinol + Epigallate ) recommends the use of this combination of dietary supplements in the combined treatment of endometrial hyperplasia (passing without atypia), adenomyosis (a type of endometriosis ) and uterine fibroids . This therapy is carried out with a single dose per day of 1-2 capsules of each drug with meals for at least 2-3 weeks and up to 6 months.
For pathologies of the genital area caused by human papillomavirus , Indinol is prescribed orally, 1 capsule once every 24 hours, in combination with therapeutic agents - immunomodulators , which are advisable to use as standard therapy for such diseases. In this case, the patient’s sexual partner must undergo a similar therapeutic course.
It should be remembered that it is prohibited to prescribe Indinol yourself; before taking this dietary supplement, the patient must consult with his or her doctor.
Overdose
There are no confirmed facts of any negative effects when taking excessive doses of Indinol.
Interaction
The parallel use of capsules of this dietary supplement and medications that reduce gastric acidity is not recommended.
Terms of sale
Available for free sale.
Storage conditions
Capsules should be stored at normal temperatures up to 25°C.
Best before date
2 years from the date of production of capsules.
Indinol analogs
Analogues of this drug include dietary supplements or medications with a similar main effect:
Of course, today you can buy analogues in pharmacies that are cheaper than Indinol, but when choosing such drugs, you should first of all take into account the effectiveness of the product being purchased, as well as the number of therapeutic units in the package (tablets, capsules).
Thus, it is best to leave the determination of a possible replacement for this dietary supplement at the discretion of a doctor or qualified pharmacist.
The average price of Indinol analogues at the moment is: Epigallate No. 120 – 2000 rubles; Mastodinon No. 60 – 480 rubles; Milona-5 No. 100 – 170 rubles; Mastofit No. 100 – 300 rubles; Estrovel No. 30 – 500 rubles.
Indinol or Mastodinon - which is better?
Although these two drugs are indicated for use in mastopathy of fibrocystic etiology and are quite often included in the treatment regimens of some doctors, they are completely different in composition and belong to different pharmacological groups.
Both the dietary supplement Indinol and the homeopathic remedy Mastodinon for mastopathy may be quite effective or, on the contrary, may not be suitable for a certain patient.
In this case, one should rely on the experience and qualifications of the attending physician and the response of the patient’s body to the treatment.
Indinol or Indinol Forto - which is better?
The question of what is the difference between Indinol and Indinol Forto , or what is the difference between these two products from the same manufacturer, JSC MiraxBioPharma, often arises in various forums devoted to the problem of treating neoplasms of the female reproductive system.
Both of these drugs include a similar active ingredient - indole-3-carbinol , which naturally unites them in their scope of application, side effects, contraindications and other parameters, but they belong to different pharmacological groups.
The main difference between these drugs is that Indinol, which, by the way, is the precursor of Indinol Forto , belongs to dietary supplements, while Indinol Forto is already a full-fledged drug with a better purified active ingredient, found in the drug in a higher dosage (200 mg) , which makes it easier to take and increases the effectiveness of treatment. In clinical practice, both of these drugs have proven themselves to be positive and therefore still remain quite competitive.
For children
This biological supplement is not intended for use in children.
During pregnancy (and lactation)
Pregnant and lactating women are prohibited from taking capsules of this dietary supplement.
Reviews for Indinol
Quite often, when women are diagnosed with the development of hyperplastic processes occurring in the mammary glands and genitals, Indinol is included in the treatment regimen for these pathological conditions.
Reviews from gynecologists, mammologists and oncologists in most cases position this dietary supplement as a fairly effective preventive agent, but not suitable for every patient.
For example, reviews for mastopathy about this dietary supplement are divided approximately equally between positive and negative, but reviews for HPV ( papillomavirus ) are most often positive.
Good results of preventive treatment are shown by taking the complex of biological additives Indinol + Epigallate when used for hyperplastic changes in the female genital organs.
Reviews for endometriosis , hyperplasia and reviews for uterine fibroids about the effectiveness of the combined action of these dietary supplements are usually positive or in some cases neutral. Negative reviews for Indinol + Epigallate , as well as for each of these dietary supplements separately, are not common and are mainly associated with personal hypersensitivity to the ingredients of the drugs, due to which patients developed various side effects when taking them.
Indinol price, where to buy
In all regions of Russia, the cost of Indinol is almost the same. On average, today you can buy Indinol in Moscow at a price of 1300 rubles for 60 capsules and 2400 rubles for 120 capsules; the average price of Indinol + Epigallate for a set of 120 capsules + 120 capsules is 3,700 rubles.
To avoid misunderstandings, when purchasing this dietary supplement in pharmacies, you should tell the pharmacist exactly its name, since there are very similar drugs on the pharmaceutical market, for example, “ Indole Evalar ”.
Source: https://medside.ru/indinol