A mucolytic with detoxifying properties ACC (code ATC R05CB01) contains one active component – acetylcysteine.
Acetylcysteine dilutes and removes mucus of any nature, impairs the ability of bacteria to attach to the walls of the respiratory tract, and prevents inflammation of the mucous membrane. This substance also cleanses the liver in cases of paracetamol overdose and poisoning with phenols, dichloroethane, and aldehydes.
ACC can be replaced with an analogue with an identical composition, release form and dosage, or with products with other active ingredients, but a similar therapeutic effect.
Synonyms of the drug
Structural analogues of the drug ACC are all single-component drugs with the ATC code R05CB01 , which contain only acetylcysteine. These synonyms are 100% identical in indications, pharmacodynamics, therapeutic effect and interaction with substances of other medications.
List of structural analogues of ACC:
- Exomyuk 200;
- Mukobene;
- N-AC-Ratiopharm;
- Vicks Active ExpectoMed;
- Mukonex;
- N-acetylcysteine;
- Acetylcysteine SEDICO;
- Acestine;
- Mucomist;
- Fluimucil.
For patients over 14 years of age, if it is necessary to replace ACC Long, it is necessary to select an extended-acting analogue. Due to the increased content of acetylcysteine, these medications have an effect for more than 4 hours after use, so they are allowed to be taken once a day.
Synonymous analogs of ACC Long with a dose of acetylcysteine 600 mg:
- effervescent tablets – Atsestad, Asibrox;
- powder for oral solution - Espa-Nat, Atete, Eucabal, Cofacin;
- granules for oral solution – Acysteine plus, Acetal C.
Most synonyms differ from ACC in the composition of auxiliary components. Therefore, according to the instructions, you need to familiarize yourself with the contraindications and features of use of each analogue chosen for replacement.
Drugs with similar effects
Instead of ACC, you can take a mucolytic that matches it in the fourth level of the ATC code. They have the same action and indications as acetylcysteine, but contain other active components.
With what substances are mucolytics analogues of ACC:
- erdosteine;
- ambroxol;
- carbocysteine;
- Bromhexine.
Important! Each substance has individual contraindications and application features. Therefore, before using the analogue, you should read the instructions and consult with your doctor.
Preparations with erdosteine
Erdostein is a substance with mucolytic, expectorant properties.
It is an analogue of acetylcysteine, since it also thins viscous sputum, improves its outflow in acute or chronic diseases of the respiratory system, inhibits free radicals and increases immunoglobulin A in the mucosa, preventing inflammation of the membrane. Even in smokers, erdostein prevents the harmful effects of tobacco smoke on α1-antitrypsin and granulocytes, which other analogues of the mucolytic ACC do not have.
Preparations with erdostein are used for pneumonia, sinusitis, bronchitis, COPD, nasopharyngitis. The effect is observed on the 4th day from the start of using medications with this substance.
Similar ACC drugs with erdosteine and average price (in rubles):
- Mucitus 300 mg – 450;
- Erdomed 300 mg – 600;
- Ermucin 175 mg/5 ml – 550.
To replace ACC, analogs with erdostein cannot be used in the treatment of children under 2 years of age, in the 1st trimester of pregnancy, with intolerance to the constituent components, liver dysfunction, or kidney failure. The drugs should not be used by people diagnosed with phenylketonuria or homocystinuria.
Preparations with ambroxol
The substance ambroxol has expectorant and mucolytic properties . The half-life reaches 12 hours. Preparations containing it are used in the formation of abnormal sputum (ICD code 10 R09.3). They are also prescribed in the treatment of asthma, bronchiectasis, pneumonia, COPD, bronchitis and respiratory distress in infants.
The action of the substance ambroxol is similar to the drug ACC, but additionally weakly suppresses cough and is concentrated more in the lung tissues. Therefore, for bronchitis, it is better to combine ambroxol with acetylcysteine. The drug also increases the level of doxycycline, cefuroxime and erythromycin in bronchial secretions.
Analogs of the mucolytic ACC with ambroxol and minimum cost (in rubles):
- Abrol Sr – 200;
- Flavamed – 120;
- Lazolvan – 150;
- Remebrox – 230;
- Ambrobene – 115;
- Suprima – 100;
- Ambrohexal – 120;
- Ambrosan – 110;
- Neo-Bronchol – 125;
- Halixol – 112;
- Lazolex – 223;
- Ambrolitin – 103;
- Ambrochem - 104.
To replace ACC, Medox, Lazongin and other analogues with ambroxol should not be taken if you are hypersensitive to their composition. Such medications are also contraindicated for people with gastrointestinal ulcers, convulsive syndrome, pregnant or lactating women. Simultaneous therapy with antitussives is prohibited. The dosage of the analogue is selected according to the age category of the patient.
Preparations with carbocisteine
The substance carbocisteine has a mucolytic, expectorant effect. It activates mucosal regeneration processes, reduces mucus production, and enhances the effect of theophylline and antibiotics. Preparations containing it are used for sinusitis, otitis, and respiratory diseases with profuse, viscous sputum.
Analogs of ACC with carbocisteine and their minimum price (in rubles):
- Bronchobos – 328;
- Libexin – 409;
- solution for infusion Mukosol – 97;
- Fluifort – 299;
- Fluditek – 374;
- Mukolik – 107;
- Bronchomucin – 152;
- other medicines with carbocisteine.
To replace ACC, the drugs Rinatiol, Langes and other analogues with carbocysteine cannot be combined with antitussive or atropine-like drugs. They are prohibited for use by lactating women, pregnant women, people with carbocisteine intolerance, gastrointestinal ulcers, glomerulonephritis, cystitis.
Preparations with bromhexine
The substance bromhexine has a mucolytic, expectorant effect. Additionally, it is a drug that suppresses cough and promotes the production of a protein-phospholipid mixture (surfactant), which helps lung tissue absorb oxygen.
Analogues with bromhexine, like ACC, are used for cystic fibrosis, cystic fibrosis, pneumonia, asthma, cough, bronchitis, COPD, diseases with the presence of viscous sputum and additionally pneumoconiosis, emphysema, tuberculosis. In treatment, it is recommended to combine it with eucalyptus, menthol and anise oil - they increase the therapeutic effect of bromhexine.
Analogs for replacing ACC based on bromhexine and their minimum price (in rubles):
- Solvin – 62;
- Bromhexine-4 Berlin-Chemie – 135;
- other medicines containing bromhexine.
Bronchohex, Phlegamine, Flekoksin and other substitutes for ACC with bromhexine are incompatible with alkali-containing solutions; it is contraindicated to use codeine with the substance. ACC analogues based on bromhexine should not be taken in the 1st trimester of pregnancy and in people with hypersensitivity to the components of the drug.
Combination drugs
To replace ACC, doctors can also recommend non-single-component analogues of mucolytics produced domestically or abroad. The combination of ingredients in their composition increases the effect of each substance and expands the spectrum of action of the medicine.
Multicomponent analogues and their minimum cost (in rubles):
- Rinicold Broncho (ambroxol + guaifenesin + phenylephrine + chlorpheniramine) – 160;
- Pulmobreeze (acetylcysteine + ambroxol) – 190;
- Respix (acetylcysteine + ambroxol) – 230;
- Helpex (acetylcysteine + ambroxol) – 300;
- Paralen Combi (bromhexine + oils of oregano, fennel, eucalyptus, mint, anise, levomenthol) – 93;
- Milistan for cough (ambroxol + carbocysteine) – 144.
You can buy these drugs to replace ACC only on the recommendation of a doctor, since they contain several substances . The active components of such analogues have various contraindications, and their effect may negatively change during treatment with drugs of other groups.
Inexpensive Russian-made mucolytics
Not all domestically produced mucolytics are cheap analogues of ACC for cough. The price of the drug depends on the cost of the substances in the composition, new developments and the volume of research conducted, and advertising costs.
Russian analogues of ACCs and their minimum price (in rubles):
- Elmucin – 220;
- Ambroxol – 52;
- Bronchosol – 92;
- Orvis Broncho – 124;
- Thoraxol Solution Tablets – 115;
- Bronchostop – 325.
Pharmacies sell an inexpensive analogue of ACC: Bronchorus or Bromhexine. These domestic preparations contain ambroxol or bromhexine.
Comparison of cheap ACC analogues:
Active substance | Ambroxol | Bromhexine | |
Release forms | Syrup 3 mg/1 ml | Syrup 4 mg/5 ml or 8 mg/5 ml | |
Tablets 30 mg | |||
Tablets 4 mg (for a child) or 8 mg | |||
Oral solution 4 mg/5 ml | |||
Or. drops 8 mg/1 ml | |||
Dragee 8 mg | |||
Action | Mucolytic, expectorant | Mucolytic, expectorant, antitussive | |
Indication | COPD, asthma, bronchitis, laryngotracheitis, pneumonia, bronchiectasis, cough | ||
Method of administration | After food, the prescribed dosage is taken orally and washed down with plenty of water. | After meals, take orally according to the prescribed dose; do not wash it down with alkaline mineral waters. | |
Daily dosage | 0–2 years | 15 mg | 6 mg |
2–5 years | 23 mg | 12 mg | |
6–9 years | 24 mg | ||
6–12 years | 45 mg | ||
After 13 years | 90 mg | ||
After 10 years | 32 mg | ||
Contraindications | Pregnancy, composition intolerance, lactation | ||
Drug interactions | Cannot be combined with antitussive medications | ||
Price (in rubles) | Tablets 30 mg No. 20 – 16 | Syrup 4 mg/5 ml 100 g – 93 | |
Syrup 3 mg/1 ml 100 ml – 45 | Tablets 8 mg No. 20 – 11 | ||
Dragee 8 mg No. 20 – 38 |
Important! When selecting an analogue instead of ACC, you must be guided by the recommendations of the attending physician about the required active ingredients, since the doctor calculates their compatibility with other medications. And it is better to refuse to buy at non-specialized outlets, or if the medicine is sold too cheap compared to manufacturer prices - it may be counterfeit.
Sources:
Vidal : https://www.vidal.ru/drugs/acc__3281 GRLS : https://grls.rosminzdrav.ru/Grls_View_v2.aspx?routingGuid=44e01d87-2e4b-40d0-9c82-0052960e36b3&t=
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Source: https://pillsman.org/26588-analogi-acc.html
Cheap analogues of ACC and ACC long for cough for children
Inflammatory infectious processes are the most common pathologies among children and adults. There are many drugs against diseases of this group. In most cases, such medications have a targeted effect.
Characteristics of ACC
Modern pharmaceutical companies offer a wide selection of drugs to eliminate phlegm, relieve coughs and treat the respiratory tract. One of the medicines that has earned positive reviews is ACC.
The medication is available in the form of powder for suspension and dissolving tablets. The remedy is recommended for the treatment of tracheitis, bronchitis, sinusitis, laryngitis and other similar diseases.
The product is effective in its action, however, in some cases its composition (acetylcysteine, sodium bicarbonate, mannitol, ascorbic acid, sodium citrate) may be contraindicated or the patient may experience side effects.
In such cases, analogues of ACC are prescribed, which have a similar mucolytic effect. The attending physician will advise how to replace the original drug, taking into account all the characteristics of the patient’s body.
The cost of the ACC drug is from 250 rubles.
Lazolvan
The drug begins to act after half an hour due to rapid penetration into the blood.
The drug contains the following components:
- ambroxol (active substance);
- acacia gum;
- karion;
- soritol;
- essential oil of mint and eucalyptus.
The product is available in the form of tablets, syrup, lozenges and solution. Depending on the form of release, the composition of the drug and its cost may vary.
Indications include a number of respiratory tract diseases in chronic and acute forms:
- pneumonia;
- bronchitis;
- bronchial asthma;
- cough;
- other diseases.
Before starting treatment with Lazolvan, you should be sure that there are no contraindications (pregnancy in the second and third trimester, kidney pathologies and allergies to the composition).
When treating children, it is necessary to correctly select the type of drug relative to its release form. Lozenges and syrup are recommended for children.
Which is better to choose ACC or Lazolvan?
The drugs cannot be called structural analogues, since their active substances are different. The countries of origin are also different.
If we compare drugs by release form, Lazolvan wins here, which is produced in five forms - tablets, solution, syrup, capsules and spray.
ACC has only three forms of release - effervescent tablets, syrup and granules for preparing a solution.
Both drugs are intended to solve the same problem, sputum discharge, but their mechanisms of action are different. The advantage of ACC is its antibacterial and antitoxic effect. Pediatricians often prescribe Lazolvan, since it can be used from an early age, and ACC only from two years of age.
To summarize, it is difficult to say with any certainty which drug is better, so before purchasing a drug, it is best to rely on your doctor.
Ambrobene
The effect on the inflamed area begins after 30 minutes and lasts up to 12 hours. With regular use, a cumulative effect is established.
In pharmacies you can purchase Ambrobene in the form of tablets, capsules, syrup, as well as a solution for inhalation and internal administration. For complex forms of respiratory tract diseases, inhalation with the solution is recommended.
The capsules contain:
- ambroxol;
- sodium (carboxymethylcellulose);
- colloidal silicon;
- cellulose;
- titanium dioxide.
The ACC analogue is used according to the following indications:
- bronchitis of varying degrees of development;
- pneumonia;
- asthma (bronchial);
- and others.
The list of contraindications is slightly longer than that of Lazolvan:
- epileptic syndrome;
- intolerance to components;
- stomach or duodenal ulcer;
- pregnancy in the first trimester and lactation.
What is better ACC or Ambrobene?
The medicines are not structural analogues, since they have different active substances, but despite this, both have the same task, to eliminate phlegm and relieve the patient from coughing. In terms of dosage forms, ACC also loses to its analogue (three versus five).
Ambrobene has a number of advantages over ACC:
- analgesic effect;
- antiviral effect;
- removal of toxins from the body;
- elimination of inflammation.
If we compare drugs by price, then the ACC analogue clearly wins. Pack of 20 Ambrobene tablets. in an online pharmacy it costs about 145 rubles, and the same package of ACC tablets (by number of pieces) costs about 495 rubles.
To summarize, we can say that ACC is in many ways inferior to its analogue, but only a doctor will determine which is better for treatment.
Fluimucil
If we consider cheap analogues of ACC, then we can pay attention to the drug Fluimucil. The cost of the drug is 130 rubles.
The product has similar properties. Its main purpose is to remove phlegm when coughing due to the antioxidant and mucolytic effect of use. After several uses, the sputum thins and leaves the bronchi freely.
Fluimucil is sold in pharmacies in the form of solutions for internal administration, inhalation and intramuscular administration. Effervescent tablets and dissolving granules are also available.
The ACC analogue in the form of a solution consists of a group of substances:
- acetylcysteine;
- sodium benzoate;
- sodium (carmellose);
- methyl parahydroxybenzoate;
- sorbitol;
- sodium hydroxide and saccharinate.
The tablets also contain the active substance, as well as sodium bicarbonate and aspartame.
A cheap analogue of ACC for cough is used for therapeutic purposes for diseases:
- pulmonary atelectasis;
- bronchitis and its varieties;
- cystic fibrosis;
- pneumonia;
- tracheitis;
- emphysema;
- otitis;
- sinusitis;
- other pathologies of the respiratory tract.
The drug has multiple contraindications. The main ones include:
- peptic ulcers of the gastrointestinal tract (gastrointestinal tract);
- child's age up to two years (solution up to 6 years, and tablets up to 18 years);
- lactation;
- individual reaction to the composition.
Particular attention should be paid to relative contraindications.
What is better ACC or Fluimucil?
Both drugs have the same active ingredient - acetylcysteine, therefore they are structural analogues. Taking both remedies by the end of the second day will significantly reduce the cough by eliminating phlegm, and after a few days it will disappear completely.
The differences between the drugs lie in the forms of release. For example, ACC has a syrup, which Fluimucil does not have, but the second one has an inhalation solution that allows you to use the drug from an early age.
Pulmonologists consider the big disadvantage of ACC to be the fact that it does not have a solution for inhalation, as well as injections, due to which the active substance of the medicine would reach its goal faster.
If you compare the prices of drugs in online pharmacies, then effervescent cough tablets of 20 pcs. they cost about the same (about 500 rubles), but out of 10 pcs. Fluimucil tablets will be cheaper (almost 200 rubles). Otherwise, the price for the various forms is approximately the same.
To summarize, we can say that Fluimucil is a worthy analogue of ACC.
Bromhexine
Another expectorant drug is Bromhexine. Generic refers to drugs that do not have a stimulating effect on the motor functionality of the respiratory organs.
When taking Bromhexine, the viscosity of the internal secretions of the bronchi decreases, due to which the stagnant sputum that comes out when coughing is diluted. At the same time, the medicine has a local anti-infective effect, helping to reduce the inflammatory process.
The components of the drug act when they accumulate in the body. Therefore, the medicine is used for a course of treatment. The effect begins to be observed after three to four days.
Compound:
- hydrochloride (bromhexine);
- sugar (milk);
- ruberosum;
- calcium stearate.
Indications include pathologies of the lungs and bronchi:
- bronchial asthma;
- complications of bronchitis;
- pneumoconiosis;
- emphysema;
- pneumonia;
- pulmonary tuberculosis;
- cystic fibrosis.
Contraindications to Bromhyxine are solely reactions to the constituent substances.
Which is better ACC or Bromhexine?
Medicines are not structural analogues, as they have different active components. Both medications are mucolytic agents and affect the thinning of sputum and the elimination of cough.
It is not uncommon for doctors to prescribe both drugs at the same time, since the effect of Bromhexine directly suppresses cough, while ACC acts remotely. This ligament has a double effect and allows you to speed up the recovery time.
But this does not mean at all that you can independently decide on the complex use of medications.
Everything depends on the clinical picture of the inflammatory process, so you need to consult your doctor.
Bromhexine is the cheapest analogue and its average cost among all forms is 109 rubles, and the average cost of ACC among all forms is 301 rubles.
When making a decision when choosing a medication, you should not rely only on the price, since the clinical picture of the disease plays an important role, and here you should rely on the doctor’s recommendation.
Ascoril
When taking the medication, an expectorant effect is observed, sputum is thinned, pulmonary spasms are eliminated and natural beta receptors of the respiratory system are stimulated.
Ascoril is an average-priced medicine. Its cost is from 220 to 270 rubles.
The combined composition includes several active components:
- guaifenesin;
- salbutamol;
- Bromhexine.
Additional composition:
- silica;
- calcium hydrophosphate;
- magnesium stearate;
- silicon dioxide.
The drug with instructions for use similar to ACC is intended for the treatment of:
- tuberculosis;
- whooping cough;
- asthma;
- tracheobronchitis;
- pneumonia;
- other diseases.
Ascoril is contraindicated in myocarditis, pregnancy, breastfeeding, high blood pressure, and gastrointestinal ulcers. You can study the contraindications in more detail in the annotation for the drug.
What is better ACC or Ascoril?
The drugs are not structural analogues, since they do not have the same active substance. Unlike all other analogues of ACC, Ascoril has three active components, therefore it has a more powerful therapeutic effect.
A special difference between the drug is that Ascoril cannot be used when coughing, without signs of suffocation.
If you compare the drug by price, then in some places ACC will cost more, and in others Ascoril. For example, Ascoril tablets of 20 pcs. cost 354 rubles, and ACC tablets of 20 pcs. cost 501 rubles. ACC syrup 200 ml. costs 302 rubles, and Ascoril syrup with the same volume will cost 406 rubles.
Conclusion
If you decide to use ACC analogues, you should read the instructions in full and consult your doctor. Independent selection of substitutes can provoke an exacerbation of concomitant diseases or cause serious side effects.
Source: https://medanalogi.com/a/acc.html
Cheap analogues and substitutes for the drug ACC for children and adults
ACC is a popular cough medicine with an active mucolytic effect. The anti-inflammatory drug is especially effective in the treatment of respiratory diseases with the presence of purulent sputum.
Pharmacies sell effervescent tablets, syrup, and soluble powder under the ACC brand. It has a pleasant sweetish taste, which explains the prevalence of its use for children.
The active ingredient is acetylcysteine, which has the ability to facilitate the process of expectoration of sputum and mucus.
It is advisable to prescribe the ACC drug for diseases of the bronchopulmonary system at the stage of the onset of a productive cough, profuse and wet, and also if there is an inflammatory process in the secretion.
The average price of a medicine is from 120 to 350 rubles , depending on the amount of medicine in the package, as well as on the concentration of the active substance.
Below is a list in which cheap analogues of the drug are selected, according to the country of origin.
Russian-made analogues
Cough is a common symptom of ARVI and other colds. There are a huge number of medications designed to treat this problem. Among the domestically produced drugs there are many inexpensive synonyms of ACC, which our mothers and grandmothers have used for years, taking care of our health.
A drug | Average cost in pharmacies | Description |
Mukaltin | 16 rubles | Herbal tablets. The active ingredient is the root of the marshmallow herb. Facilitates the process of expectoration, an excellent anti-inflammatory drug. Indicated for wet, productive cough. The cheapest close substitute for ACC. |
Pectusin | 18 rubles | An expectorant thins mucus and speeds up its removal from the respiratory tract. Release form: syrup. Combined medicine of plant origin. The composition of the medicine includes thyme extract, thyme extract, as well as potassium bromide, ethyl alcohol and sugar syrup. Due to the presence of alcohol, the drug is not prescribed during pregnancy and lactation. |
Bromhexine | From 20 rubles | Indications for use: respiratory tract diseases accompanied by the presence of viscous and difficult to separate secretions. Effective for bronchitis, cystic fibrosis, bronchial asthma, chronic pneumonia, tracheobronchitis. |
Bronchostop | From 340 rubles | The release form of the drug is syrup, lozenges for resorption. Excellently dilutes bronchial secretions and promotes the formation of surfactant. |
Acetylcysteine | From 220 rubles | Effervescent tablets with the same active ingredient as ACC. Has similar characteristics and properties. |
Ukrainian substitutes
Let's consider Ukrainian-made drugs that are close substitutes for the original medication:
- Ambroxol . Mucolytic agent used for bronchitis, pneumonia, tuberculosis, bronchial asthma. Do not take the medicine in combination with antitussive components. The average price is 20 rubles.
- Ambrotard 75 . Long-acting capsules. An expectorant that facilitates the removal of secretions from the lower respiratory tract. Not recommended for children under 12 years of age. The average price is 90 rubles.
- Pertusin . Available in the form of sweet sugar syrup. The composition of the medicine includes thyme extract and potassium bromide. Can be used during pregnancy. The average price is 55 rubles.
- Salbroxol . The active ingredient is ambroxol. Expectorant, anti-inflammatory component. Indicated for bronchitis and asthma. It has an extensive list of contraindications. The average price is 40 rubles.
Belarusian generics
Belarusian generics of ACC are actively used in the treatment of respiratory diseases accompanied by the presence of viscous or purulent sputum.
Reasonable prices and widespread availability made them worthy competitors to drugs from domestic manufacturers and other imported ones.
- Atseteson . The average price is from 30 to 95 rubles. Release form: powder with orange scent. Use is possible for diseases of the bronchopulmonary system. The active substance is acetylcysteine.
- Acecex Pharma . The average price is from 15 to 55 rubles. Powder for preparing a solution. Facilitates the removal of mucus and helps the expectoration process. Has strong antioxidant properties.
- Acetsemed . The average price is from 70 to 240 rubles. Soluble bulk mixture. Prescribed for respiratory diseases with thick and poorly separated secretions in the respiratory tract.
Other foreign analogues
Replacing with a cheap medicine among imported medicines is not always possible. Foreign analogues have a higher price, having the same properties. The table below shows the most popular medications marked “cheaper”.
A drug | Average cost in pharmacies | Peculiarities |
Fluimucil | From 195 rubles | Country of origin: Italy, Switzerland. Release form: effervescent tablets, powder. Mucolytic agent with the active substance – acetylcysteine. A modern medicine that increases the volume of mucus, promoting the removal of purulent sputum. For children, fluimucil can be used after 6 years of age. |
Mukobene | From 180 rubles | Country of origin: Austria. Available in the form of powder and soluble effervescent tablets. Prescribed for productive wet cough. In order to prevent respiratory complications in the postoperative period. |
Fluditek | From 160 rubles | An effective cough remedy for difficult sputum evacuation. The drug can be taken by children from 1 month, as well as during lactation. During pregnancy, the medicine is allowed to be taken in the 2nd and 3rd trimesters. |
When choosing cough medications, it is important to understand the significant difference between mucolytic and antitussive medications. Under no circumstances should these medications be taken at the same time, as they may worsen the severity of the disease.
The principle of action of mucolytics is to promote the formation of sputum and its separation. Antitussive medications eliminate reflex cough, thereby allowing a large volume of sputum to remain inside.
ACC and all the medications indicated in the article are mucolytic agents that need to be used only when the cough has entered the wet and productive phase. The selection of the necessary synonym should be carried out together with the attending physician.
Source: https://LadyTrand.ru/lekarstva/acc-analogi-spisok.html
Cheap analogues of ACC, price of Russian and imported cough medicines
Effective and inexpensive analogues-substitutes of ACC
ACC treats lesions of the respiratory tract that are complicated by difficult sputum separation, such as bronchitis, tracheitis, pneumonia. The original product based on Acetylcysteine is quite popular due to its high effectiveness. However, the drug is no exception to the rule, and it also has a number of cheap analogues, like many other drugs. Below we will talk about such substitutes and the individual characteristics of specific positions.
The essence of the action
The distinctive properties of the drug ACC are determined by the substance Acetylcysteine, which acts against cough as follows:
- Mucolytic. In other words, it reduces the viscosity of sputum, which further accelerates the process of its removal.
- Reduces the ability of bacterial cells to adhesion, or stick, to the mucous layer of the bronchi.
- Antioxidant properties help neutralize the harmful effect of free particles, which, when entering the lungs with air, can cause disease.
- The anti-inflammatory effect is observed due to the elimination of pathogenic factors (microbes, toxins) through antioxidant activity.
What does the drug treat?
Indications for use:
The drug is used for diseases of the respiratory tract affecting both the upper and lower sections. The main point that unites all the indications of the pharmaceutical product is the presence of sputum formation, which, due to its thick, viscous consistency, does not drain well, which further forms an abundant accumulation of mucous secretion in the bronchi.
Some of the indications with characteristic hard-to-discharge sputum:
- Bronchitis acute, chronic, obstructive;
- Inflammation of the trachea, laryngotracheitis;
- Bronchial asthma;
- Bronchiectactic disease;
- Pneumonia, lung abscess;
- Pulmonary obstructive disease (COPD);
- Bronchiolitis, cystic fibrosis;
- Sinusitis, otitis media.
The benefits of the medicine for the above chronic diseases are noticeable in reducing the severity and frequency of exacerbations; in acute forms, the onset of recovery is accelerated.
It is noteworthy that the mucolytic qualities of ACC similarly extend to purulent-exudative processes.
Contraindications
Prescription is not recommended for:
- The appearance of bloody spots in expectorated mucus;
- Pulmonary hemorrhages;
- Exacerbation of stomach and duodenal ulcers;
- Pregnant and breastfeeding women;
- Personal intolerance to Acetylcysteine. This is indicated by itching, headache, and runny nose of non-inflammatory origin.
ACC, dosed at 100 and 200 mg, is prohibited for children under 2 years of age. The enhanced dosage form of 600 mg is dangerous for children under 14 years of age.
Possible negative effects
In rare cases, there may be: nausea, vomiting, heartburn, skin rashes and itching.
Patients with liver or kidney failure require more gentle therapy with this mucolytic, because most of the metabolic transformations are carried out by the liver, and primary excretion from the body is carried out by the kidneys.
Important instructions for use
All forms of ACC are taken orally after meals. The duration of treatment depends on individual needs, but for colds it most often lasts 5-7 days.
It is advised to avoid taking it immediately before going to bed and take it last before 18.00.
When using antibiotics simultaneously with a pharmaceutical drug, a break between their consumption of 1-2 hours is necessary.
Introductory instructions for use:
- The standard method of taking the drug for adults and children over 14 years of age is: 200 mg in 2-3 approaches per day.
- Children from 6 to 14 years old are prescribed 100 mg 2-3 per day.
- For ages 2 to 6 years, 1 effervescent tablet of 100 mg is recommended once a day. If it is syrup or soluble granules 100 mg, take it 2-3 times a day.
- If you have a very severe cough, a dosage of 600 mg is indicated, which should not be taken more than once a day.
- If you use a syringe dispenser supplied with baby syrup, it must be rinsed with clean water each time after use.
- Effervescent tablets should be consumed immediately after preparing the solution.
- The granules can be diluted with water, juice or tea drink.
An additional therapeutic measure that accelerates the recovery process is to increase the volume of fluid consumed, which has a positive effect on the mucolytic dynamics of the expectorant.
How much does ACC cost: price in pharmacies
The cost of German medicine starts from 120 rubles. and reaches 600 rubles. Any drug in the line can be purchased without a prescription.
List of synonyms of Russian and foreign production
The table contains examples of analogs of a wide variety of dosage forms. The indicated absence of some items is meant at the time of writing only on designated pharmacy web resources, but does not indicate a shortage of a particular drug in pharmacies throughout the country as a whole, including in the regions of Moscow and St. Petersburg.
The name of the analogue is cheaper than the drug ACC | Apteka.ru (price in rub.) | Piluli.ru (price in rub.) | ||
Moscow | St. Petersburg | Moscow | St. Petersburg | |
Rinofluimucil (intranasal spray) | 305 | 323 | 275 | 252 |
Espa-nat (packages) | 142 | 153 | — | — |
Fluimucil (effervescent tablets) | — | — | 137 | 126 |
Thoraxol Solution Tablets (soluble tablets) | 135 | 145 | — | — |
Neo-bronchol (tablet for resorption) | — | 155 | 147 | 127 |
Ambroxol (solution) | 89 | 91 | — | — |
Bromhexine (tablets) | 54 | 87 | 47 | 63 |
Rinofluimucil (Italy)
The only one of the listed analogues used externally. The spray can replace internal medications if you have rhinitis with thick mucus.
Espa-naz (Germany)
Affordable high quality generic. The orange-flavored mucolytic has an expectorant effect on productive coughs, inhibiting the accumulation of mucus in the bronchi and facilitating its unhindered discharge.
Fluimucil (Italy)
A European synonym with a lower cost, while maintaining compliance with quality requirements.
Regarding the timely use of Fluimucil for cough, a number of experts note its benefits, which can be traced to a reduction in the need for antibacterial therapy.
There is also a significant reduction in the severity of inflammation, which in turn prevents complications.
A decrease in general intoxication is obvious, which is greatly facilitated by the antioxidant properties of Acetylcysteine, which is part of the composition.
Thoraxol Solution Tablets (Russia)
A domestic, relatively inexpensive substitute, which is of interest in the modern form of a dispersible tablet.
Relief of cough associated with the formation of viscous sputum, either acute or chronic, occurs by stimulating the activity of the ciliated membrane of the bronchi and by reducing the viscosity of mucous formations.
All this together creates conditions for faster spontaneous cleansing of the surface of the mucous layer.
It is worth considering that Thoraxol only works in the presence of lesions in the lower part of the respiratory system: bronchitis, obstructive disease, pneumonia.
The active substance does not lose its mucolytic qualities regardless of the method of administration, and there are several of them:
- Divide the tablet in half and drink the whole tablet without water. Once in the stomach, it quickly begins to dissolve. This method is convenient if you do not have time to prepare a portion of the medicine.
- Dissolve in 20 ml of water, then immediately take the resulting suspension.
- Drink the whole one with a small portion of water.
Lactation and the first three months of pregnancy are the main contraindications for Thoraxol.
Neo-bronchol (Germany)
Cheaper expectorant tablets, the main advantages of which are:
- Lack of sugar (sorbitol serves as a sweetener);
- The type of dosage form intended exclusively for resorption does not require any additional manipulations.
The drug acts within the first half hour after administration and continues to reveal mucolytic activity after 6-12 hours.
In rare situations, the undesirable effects of Neo-bronchol are expressed by skin reactions and stomach upset.
Ambroxol (RF)
An inexpensive way to deal with a difficult wet cough. The description of the pharmacological route of action of Ambroxol has already been mentioned above.
The types of dosage forms produced by Russian companies are varied: syrups, regular tablets, solutions.
Tablets cost the least, but the inhalation solution attracts the most attention as the most modern method of mucolytic therapy.
Some of the advantages of the inhalation route of administration of Ambroxol:
- Rapid access to the site of inflammation;
- A comfortable level of hydration of the respiratory organs, namely the bronchial mucosa, is achieved;
- The natural physiological outflow of mucus and its dilution are improved.
Taken together, these factors significantly accelerate the process of onset of the therapeutic effect.
Bromhexine is the cheapest alternative from Germany
The main goal of Bromhexine is to eliminate the high coefficient of mucus thickness, which for this reason does not clear well and causes a cough reflex.
Interestingly, after the biotransformation of Bromhexine in the liver, the active metabolite Ambroxol is formed. It is he who ultimately determines all its properties.
Conclusions on available replacements
It is unacceptable to combine cough treatment with an expectorant group with an antitussive group, otherwise the suppression of the cough reflex by the latter will lead to the opposite effect - difficulties will be created in removing accumulated mucus from the bronchi. In any case, the correct selection of treatment should be carried out with the participation of a doctor in order to identify hidden, sluggish symptoms of the disease in time, thereby avoiding the transition of an acute condition to a chronic one.
Source: http://analogi-deshevle.ru/acc-cena.html
Cough medicine ACC: indications, use, cheap analogues
Many colds are accompanied by a cough, which is a reflex act to eliminate irritants from the bronchi and trachea. A dry cough is especially uncomfortable.
To improve sputum production and alleviate the condition, doctors prescribe special antitussive drugs.
In this case, the drug ACC is actively used, which helps to increase the volume and dilute the viscosity of the secretion, facilitating its removal from the respiratory tract.
Composition and properties of the drug
The active substance of ACC is acetylcysteine, the maximum concentration in the blood is reached within two hours after use.
Acetylcysteine has the following effects on the body:
- detoxifying;
- mucolytic;
- expectorant.
The drug is produced in effervescent tablets, solutions for intravenous and intramuscular administration, and in granules from which a solution for oral administration is prepared.
Indications
All dosage forms of ACC are intended for the treatment of:
- tracheitis;
- bronchiectasis;
- obstructive bronchitis;
- pneumonia;
- acute and chronic bronchitis;
- lung abscess;
- bronchiolitis;
- laryngotracheitis;
- cystic fibrosis;
- bronchial asthma.
If these diseases are accompanied by a cough with difficult to separate viscous sputum, then ACC is prescribed. It can also be used to treat chronic and acute sinusitis, otitis media.
Instructions for use
The method and dose of use depends on the age of the patient and the dosage form of the drug.
Effervescent tablets are dissolved in half a glass of water immediately before use and taken after meals. The daily dose for adults is one 200 mg tablet twice or thrice a day. For cystic fibrosis, the maximum daily dose can be increased to 800 mg.
Orange granules are diluted in boiled chilled water, juice or iced tea. To dissolve the granules with lemon and honey, you need to take a glass of hot water. For adults, the daily dose of the solution corresponds to the dose of tablets - from 400 to 600 mg. You can take the syrup twice or three times a day.
The duration of therapy is prescribed by the attending physician. In most cases it lasts for 5–7 days. For cystic fibrosis and chronic bronchitis, the drug can be used for a long time to prevent infections.
Contraindications
The cough medicine ACC is contraindicated for use in the following conditions and diseases:
- Hypersensitivity to acetylcysteine or another component of the drug.
- Pregnancy and lactation.
- Pulmonary hemorrhage.
- Hemoptysis.
- Exacerbation of duodenal or gastric ulcer.
Under the supervision of a doctor, the medicine can be used in the following cases:
- Indications for children under 2 years of age.
- For certain kidney and liver diseases.
- For bronchial asthma.
- Patients with pathologies of the adrenal glands.
- For varicose veins of the esophagus.
The drug ACC is not recommended for use with other antitussive medications, as this may cause mucus stagnation.
Side effects
drug is well tolerated and there are practically no side effects observed after taking it. Rarely, headaches, stomatitis, and tinnitus may occur.
In isolated cases, the following conditions were observed:
- itching, urticaria, skin rash;
- decreased blood pressure;
- tachycardia;
- vomiting, nausea, heartburn, diarrhea;
- pulmonary hemorrhage;
- bronchospasm.
The ACC drug is effective in relieving and eliminating cough and is the key to rapid treatment of the disease. However, there are cheaper analogs of ACC that have the same mechanism of action or contain the same active substance.
Analogues of ACC are cheap
You can replace the drug with medications that contain acetylcysteine. These include:
- Acestine.
- Acetylcysteine Sedico.
- Mukonex.
- Acestate.
- Fluimucil.
The ACC analogues described below are made on the basis of other active components, but have the same pharmacological effect.
Bromexine
Mucolytic drug , which has not only an expectorant, but also an antitussive effect. The treatment effect is noticeable after two to five days of use. Prescribed for treatment:
- bronchitis;
- bronchiectasis;
- asthma;
- emphysema;
- tuberculosis;
- pneumonia.
Available in the form of drops for oral administration, tablets, dragees, syrups and solutions for oral administration, inhalation and injection. For children over fourteen years of age and adults, pills, tablets and syrup are prescribed 3-4 times a day. A single dose can be from 8 to 16 mg.
Bromhexine is contraindicated for use in the first trimester of pregnancy and during lactation, for stomach ulcers, and hypersensitivity. For some kidney and liver diseases, it must be taken with caution. It is recommended that children under six years of age be treated with the drug in the form of a syrup or solution.
Side effects of the medicine may include:
- dyspepsia, vomiting, nausea;
- allergic reactions;
- headache, dizziness;
- exacerbation of peptic ulcer disease.
To increase the expectorant effect during Bromhexine therapy, it is recommended to drink more liquid.
Mucosol
The drug contains carbocysteine, which reduces the viscosity of sputum, facilitates the discharge of secretions and mucus, and reduces cough. The lysine salt included in the active substance does not irritate the gastric mucosa because it dissolves well in water. Due to this, the daily dose of the drug can be taken at one time.
Mukosol can be bought in the form of syrup, capsules, suspensions. The daily dose for adults is from 1.5 to 2.25 mg. The duration of therapy depends on the form of the process. For diseases of the bronchopulmonary system in acute form, treatment can last about four to six days. The chronic process is treated from ten days to a month.
The drug is contraindicated in children under twelve years of age, in the first trimester of pregnancy, with hypersensitivity, peptic ulcers, fetylketonuria.
Side effects after taking Mucaltin may be:
- allergic reactions;
- malaise;
- weakness;
- dizziness;
- gastrointestinal bleeding;
- diarrhea, gastralgia, vomiting, nausea.
When taking syrup, patients with diabetes need to take into account the sucrose content in it.
Mukaltin
A herbal medicine that contains marshmallow extract. The tablets remove bronchial secretions and make coughing easier. Indicated in complex therapy for bronchitis, tracheobronchitis, pneumonia, bronchiectasis and other respiratory tract pathologies.
Prescribed in a course of seven to fourteen days from one to three tablets three times a day.
The only contraindications for use are increased individual sensitivity to the components of the product and peptic ulcer disease.
side effects . Sometimes allergic reactions may appear and very rarely - nausea and dyspepsia.
Lazolval
The mucolytic drug contains ambroxol, which has an expectorant, secretolytic and secretomotor effect. Its activity begins half an hour after ingestion and lasts from 6 to 12 hours.
Lazolvan is prescribed for the treatment of the following diseases:
- chronic and acute bronchitis;
- pneumonia;
- bronchiectasis;
- bronchial asthma;
- COPD
You can buy the drug in the form of tablets, capsules, solutions for inhalation and oral administration, effervescent tablets, solutions for intravenous administration.
The product should be taken with a small amount of liquid during meals. In the first three days, children over twelve years of age and adults are recommended to take 90 mg per day, divided into three doses. Afterwards the dose is reduced to 30 mg twice a day.
The drug is contraindicated in case of hypersensitivity, phenylketonuria and in the first trimester of pregnancy.
Side effects may include:
- allergic reactions;
- dry mouth;
- diarrhea;
- headache;
- constipation;
- exanthema.
It is not recommended to take Lazolvan with other cough medications. This may make it difficult to release secretions.
prescribed by the attending physician to soften and improve sputum discharge when coughing will significantly improve the patient’s condition and speed up recovery. Most often, the drug ACC and its analogues are used for this.
Source: https://lechim-gorlo.ru/zabolevaniya/preparat-ot-kashlya-atsts-pokazaniya-primenenie-deshevye-analogi