Codeine-containing cough medicines

Cough tablets with codeine are medications designed to eliminate a dry cough, relieve pain and improve the removal of phlegm from the lungs and throat. Codeine has been prescribed by doctors for decades to relieve coughing attacks. It has a pronounced suppressive effect.

Now medications containing this substance are over-the-counter and freely sold in pharmacies. However, there are exceptions that require a mandatory prescription by a doctor.

Almost all codeine cough tablets are available without a doctor's prescription.

Efficiency

Codeine is an opium alkaloid obtained semi-synthetically. The chemical structure of the substance is in many ways similar to morphine, but its analgesic effect is less intense. The element belongs to a class of antitussive substances called opiate (narcotic) analgesics.

Research shows that this element is highly effective in suppressing coughing attacks. Especially in the case of diseases of the upper respiratory tract and chronic lung pathologies. The component is actively used in the treatment of influenza, colds and other infectious diseases.

The main actions of tablets containing codeine:

Codeine tablets relieve pain and promote mucus removal

1. Elimination of pain and discomfort. The substance is used to dull pain after surgery or injury. The effect is observed within a few minutes and lasts for a long time. Often, medications containing codeine are prescribed when other painkillers (like Aspirin, Ibuprofen and Paracetamol) have not worked.
2. Suppression of cough. The substance acts on the brain centers, slowing down and stopping the signals responsible for coughing attacks.
3. Liquefaction of sputum. The component dilutes phlegm accumulated in the throat and lung areas.
4. Expectorant action. After taking a codeine tablet, phlegm and harmful substances are more easily eliminated from the body.
5. Sedative effect. Due to the calming effect on the central nervous system, while taking pills it is not advisable to engage in activities that require a quick reaction and increased attentiveness. These include driving a car or operating production machinery.

The effect of taking cough tablets with codeine is noticeable after 3-5 days

Additionally, codeine-containing medications may be prescribed for diarrhea. The substance is effective only in cases of mild to moderate pain. For a complex and stronger effect, it is used in combination with other medications - Paracetamol or Aspirin. For mild coughing, smaller dosages or analogues are prescribed.

It is worth remembering that codeine can only alleviate the symptoms - it will not get rid of the cause of the disease. The full effect of therapy will be noticeable after 3-5 days. In rare cases, this will take more than one week.

Taking pills over a long period of time can lead to addiction or dependence.

List of drugs containing codeine

List of the most famous cough medicines with codeine:

Codelac tablets

1. Codelac. One tablet contains 8 mg of the active element. Indicated for cough attacks of various types. Highly effective for colds. It depresses the part of the brain responsible for sending nerve impulses that lead to coughing. Thins mucus and promotes expectoration. The main consequences of taking: headaches, continued feeling of drowsiness, vomiting and nausea, constipation. May cause allergies. Accepted from 18 years of age. The duration of the effect is up to 12 hours.
2. Terpincode. One tablet contains 8 mg of the weak opiate element. A potent medicine that irritates the cough center and dilutes phlegm. Indicated for pathologies of the lungs and respiratory tract. Prescribed for adults, as well as children aged two years and older. Side effects include: nausea and vomiting, problems with bowel movements, headache, increased drowsiness. Can cause allergies. The maximum course of therapy is 5 days.
3. Codterpin.
   Codeine in one tablet is 15 mg. Indicated for the treatment of dry as well as productive cough with a strong cough reflex. Main side effects: problems with bowel movements, physical dependence due to prolonged use. The course duration is 5-10 days. Children require regular, strict medical supervision. Codipront tablets
4. Codipront. Available in the form of capsules and syrup. One capsule contains 30 mg of codeine. In 5 ml of syrup - 11.1 mg. It has a long-term effect on the body - cough can go away for a period of 12 hours. In addition to codeine, the product contains phenyltoloxamine, which has a mild sedative effect and anti-allergenic effect. Indicated for influenza, bronchitis of various types, whooping cough, infectious diseases and a number of allergic reactions that involve the upper respiratory tract. Codipront is contraindicated in children under 14 years of age (unless prescribed by a doctor), pregnant women and the elderly. Also, the medicine is not suitable for diabetes and some types of glaucoma. Side effects: headaches, increased drowsiness, blurred vision, irritability, problems with urination and bowel movements.
5. Kodesan. One tablet contains 0.0095 g of codeine phosphate. Instant medicine. Indicated for severe coughing - to suppress attacks. Allowed for use from 12 years of age. Side effects: nausea and vomiting, stomach pain, arrhythmia, arterial hypotension. The average course duration is 5 days.
6. Kodarin. One tablet contains 10.9 mg of codeine phosphate. Indicated for bronchitis, pneumonia, pharyngitis, as well as colds accompanied by a cough. Increases coughing. Available only by prescription.

The names of the listed drugs are the most well known. Most of them can be purchased without a prescription. Your doctor may prescribe other tablets containing codeine. To clarify its presence among the components, you should contact official sources.

Children's formulations most often contain a minimal dosage of the substance and are predominantly in the form of syrups rather than tablets. All medications have instructions. However, the exact dosage and duration of the course are prescribed only by a doctor - after clarifying the medical history and correct diagnosis.

Some of the listed remedies are not compatible with others. Before visiting the hospital, it is recommended that you make a list of all your medications (prescription and over-the-counter), as well as vitamins, minerals, and supplements.

Possible contraindications

Despite the fact that drugs containing the substance are available for free sale, many of them have a number of contraindications.

In the following cases, it is prohibited to take codeine formulations:

If you have thyroid problems, you should not take codeine tablets.

• presence of allergies;
• some severe pulmonary pathologies;
• head injuries and problems with cerebral blood supply;
• serious mental disorders and recent course of antidepressants;
• pathologies of the adrenal glands;
• convulsions;
• alcohol addiction;
• decreased activity of the thyroid gland;
• renal and liver pathologies;
• myasthenia gravis;
• the presence of stones and other formations in the gallbladder;
• prostate enlargement;
• Addison's disease (when the body does not produce enough of certain vital substances);
• hypotension (low blood pressure);
• Ulcerative colitis (affects the intestines).

In patients with kidney problems, the elimination of the medication slows down, which can lead to health problems. You need to use the medicine with caution and increase the intervals between doses.

It is also worth telling your doctor if you have recently had abdominal or bladder surgery. It is advisable to avoid alcohol while taking pills. Otherwise, the risk of side effects will increase.

Categories of people who should not resort to codeine treatment:

1. Small children. Codeine-containing medications should be given cautiously to children under 12 years of age unless directed by a doctor. The substance is absolutely contraindicated for children under 2 years of age. Do not give tablets to children and adolescents under 18 years of age who have had their tonsils or adenoids removed. There is a high risk of apnea (short-term cessation of breathing) during sleep.
2. Aged people. The aged human body is weakened and has increased susceptibility to this component. Additional kidney and liver problems may occur.
3. Pregnant and lactating women. And also only those planning pregnancy. The element can impair the development of a child and cause problems with his health. Some studies have documented the possibility of transmission of the composition through breast milk.
4. Professional athletes. The substance is classified as a doping substance.

This is not a complete list of contraindications. The points listed are the most common. To obtain more detailed information, consultation with a specialist is required. When prescribing medication, the doctor must take into account the presence of chronic pathologies and previous traumatic brain injuries.

Heart pain is one of the dangerous side effects of drugs containing codeine.

If side effects increase during therapy, you should inform your doctor. He will reduce the dosage or prescribe other medications. In case of severe adverse reactions (such as heart pain or difficulty breathing), you must immediately call an ambulance.

Source: https://pulmohealth.com/bolezni/kashel/sredstva/tabletki-ot-kashlya-s-kodeinom/

Codeine cough tablets

A dry, ringing cough is considered harmful and causes serious complications. Such a non-productive cough is not able to remove the mucous secretion of the bronchi with viruses or bacteria from the body. On the contrary, it promotes their movement down to the lungs. With the help of cough tablets, the process of separating phlegm and removing it from the body still occurs.

pharmachologic effect

Many experts argue that codeine is a dangerous drug and do not recommend its use unless specifically necessary and recommended by a doctor.

Its uncontrolled use can cause the most unexpected reactions of the body. Codeine is a narcotic drug of plant origin.

As for the use of codeine-containing cough preparations, their popularity is growing due to the excellent properties of suppressing the cough center. Codeine, contained in cough medicine, acts in two ways:

• eliminates pain;
• relieves debilitating cough.

Codeine-containing cough medicines can reduce toothaches, headaches, and menstrual pain.

It should be remembered that under no circumstances should you take cough suppressants containing codeine in an uncontrolled and unlimited quantity. Failure to comply with the dosage and lack of control in taking these drugs is addictive.

Codeine is a narcotic drug derived from opium, obtained by methylation of morphine.

If we compare codeine with other drugs that relieve painful symptoms and consist of narcotic substances, it becomes clear that codeine acts more gently and does not lead to serious disturbances in the human gastrointestinal tract. When this substance enters the body, it primarily affects the brain and stops the urge to cough.

After this, codeine is processed in the liver. It is worth noting that 10% of 100 are converted into morphine. Thus, an analgesic effect is obtained.

Although cough medicine containing codeine is quite effective, doctors do not always resort to its help. It is prescribed as rarely as possible, only when absolutely necessary. The reason is that codeine is considered an opium alkaloid and can cause the following side effects:

• intoxication;
• addiction to narcotic substances;
• dizziness;
• nausea, often accompanied by vomiting;
• constipation;
• allergic reaction;
• overexcited state;
• sleep disturbance.

It is important to know that codeine-containing drugs should never be taken with mucolytics or drugs with expectorant effects. Due to their combined use, too much mucus is produced and it becomes difficult to expectorate.

Preparations with codeine - indications for use

Quite often, people develop a suffocating, dry cough accompanied by a painful syndrome. In these cases, doctors recommend drugs with codeine.

Codeine cough suppressant blocks the central nervous system. It begins to act half an hour after entering the body and helps to avoid coughing for 6 hours.

The drug is strictly contraindicated for children under 2 years of age.

Drugs containing codeine are used to treat:

• bronchitis;
• emphysema;
• bronchopneumonia;
• toothache, joint pain and headache;
• various injuries;
• pain in the kidneys and liver;
• pain due to cancer;
• diarrhea;
• sharp emotional upsurge.

You should not take medications containing codeine in the following cases:

1. During pregnancy and lactation, codeine can harm the unborn baby.
2. The drug is also contraindicated in childhood and adolescence. The only exceptions are emergency cases, when it is important to eliminate severe coughing attacks as soon as possible.
3. People suffering from serious disorders of the cardiovascular system.

Popular codeine-containing cough medications

Currently, there are many types of codeine-based drugs that can relieve both dry and wet coughs. It’s worth stopping and considering those that doctors recommend using most often.

Codelac

This medicine contains:

• codeine, which is an excellent and effective antitussive;
• soda, which alkalizes sputum and helps remove it from the respiratory tract, thereby improving and facilitating the patient’s well-being. In addition, soda has a softening effect and reduces swelling;
• licorice root, which effectively helps with cramps and promotes the removal of phlegm;
• thermopsis herb, which has a positive effect on the function of secretion.

We recommend reading the article “Instructions for using cough tablets with thermopsis.”

This medicine in tablet form can be used from 12 years of age, 1 tablet three times a day for no longer than 7 days.

Codelac is strictly prohibited for children under 2 years of age.

Codelac Broncho with thyme

This drug helps cure wet cough, eliminate the cause of sputum, and also helps enhance the effect of antibiotics. It includes:

• soda;
• ambroxol;
• thermopsis;
• codeine;
• thyme.

It is important to remember that using other cough medications at the same time as this medicine is contraindicated. Available in the form of syrup and tablets. Allowed for use by children over 2 years of age for 5 days. Codelac Broncho Thyme in the form of drops can be used for children from 2 months.

Terpincode

These dry cough tablets contain:

• codeine;
• soda;
• terpinhydrate.

The drug begins its rapid action half an hour after taking it and works for 4 hours. It is recommended to use after 12 years, 1 tablet twice a day for no more than 5 days.

Tedein

This medicine for dry cough contains:

As a result of its action, mucus begins to be produced well and removed from the body. Recommended for use by children over 5 years old. The course of treatment with Tedein should not exceed 5 days.

What are the dangers of codeine?

If you use codeine-containing drugs in unlimited quantities and without a doctor’s recommendation, in addition to poisoning, addiction syndrome may develop. These two unpleasant moments are characterized by the following symptoms:

• nausea, often ending in vomiting;
• dizziness;
• insomnia and nervous agitation;
• constipation;
• allergic manifestations;
• psychological and physical dependence.

From the observations of doctors, the uncontrolled use of such drugs leads to real withdrawal after their withdrawal. This condition resembles the withdrawal symptoms of drug addicts who experience muscle pain and depression without drugs.

At such moments, they are often visited by suicidal thoughts. Many doctors are inclined to believe that such a patient’s condition after long-term use of codeine-containing drugs is much more dangerous than heroin addiction.

In addition, people who uncontrollably take drugs with codeine complain of drowsiness, problems in the functioning of the gastrointestinal tract and complete apathy.

Options for replacing codeine-containing drugs

All drugs containing codeine are sold in pharmacies strictly according to a doctor's prescription. Currently, all the actions of doctors are reduced to minimizing the use of codeine-containing drugs.

Much to the chagrin of cheap analogues, which can act just as effectively as they do not yet. But there are expensive substitutes.

For example, a doctor may recommend replacing Caffetin with Gevadal, Codelac with Stoptussin, and Codelmix with Brustan.

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Source: https://nasmork.net/tabletki-ot-kashlya-s-kodeinom/

Features of drugs with codeine for cough

Coughing is an extremely unpleasant and sometimes painful phenomenon. If it is frequent, dry, and does not bring relief, many see salvation in taking an antitussive medication. A prominent representative of this group is codeine.

The substance eliminates the very urge to “cough”. However, taking it incorrectly can have serious health consequences. We suggest you figure out when it is advisable to take codeine for a cough, and when it is absolutely forbidden.

How does codeine work?

Codeine is a semi-synthetic substance, an opium alkaloid obtained from morphine. In its pure form it looks like an odorless white crystalline powder. It tastes bitter. In medicine it is used as an antitussive and analgesic, and is also included in the ankylosing spondylitis mixture.

Drugs containing codeine have a central effect. Getting rid of a cough occurs by suppressing the cough reflex. The substance stimulates opioid receptors in brain neurons and reduces the excitation of the center that signals coughing. The antitussive effect when taken orally develops within 30-60 minutes and lasts from 4 to 6 hours.

Taken as a whole, codeine has a stimulating effect on opiate receptors throughout the central nervous system and peripheral tissues. It changes the emotional perception of pain by stimulating the antinociceptive system and relaxes smooth muscles and sphincters, which causes decreased peristalsis and respiratory depression.

Danger of the drug

Self-medication with antitussive drugs is dangerous in itself. Codeine belongs to that rare category of medicines that are truly “cough relievers”. Signals coming from the affected bronchial mucosa are simply ignored when it is used.

But a cough is not just an unpleasant symptom. With its help, the body cleanses the lungs. By turning it off, it is very easy to provoke the accumulation of sputum. If codeine syrup is used incorrectly, the consequences can be extremely serious.

Here are just a small part of them:

• bronchitis;
• pneumonia;
• violation of pulmonary ventilation.

The logic of correct and complete treatment of cough is to alleviate it, not block it. To do this, they act directly on the sputum and mucous membrane of the lungs. Sputum thinning is achieved with mucolytic agents and increased fluid intake. Expectorant syrups facilitate its removal from the walls of the bronchi. As a result, the cough becomes productive and painless.

Narcotic properties

Codeine is an opiate (heroin, morphine), and in high doses causes euphoria. When taken regularly it is addictive. By the time the drug was banned, it had had an impact on US culture.

In the southern states, codeine-containing syrups have long been used to obtain a narcotic effect. Under their influence, southern slow-motion rap was formed.

Purple drank was the name of a purple drug cocktail made from lemonade and Promethazine cough syrup with codeine.

Today, the medicine is included in List II of the List of narcotic drugs, psychotropic substances and their precursors subject to control in the Russian Federation. The over-the-counter availability of codeine has been prohibited since June 2012.

Not only the pure substance, but also medicines containing it were included in the list of prohibited substances. These are cough tablets, migraine tablets, antipyretics, painkillers.

Many of them are quite popular: Nurofen Plus, Sedal-M, Sedalgin, Solpadein, Pentalgin, Codelac, Kofex and others.

Indications for use

Codeine is a narcotic drug and is used extremely rarely for medicinal purposes, mainly in hospital settings. The indication for its use is the need to suppress cough. As a rule, this is a dry, persistent, non-productive cough. In young children, codeine use is justified for the following diseases:

• whooping cough;
• dry pleurisy;
• bronchorrhea is an intense productive cough with abundant liquid secretion with a high risk of aspiration.

If the child is older or the adult is ill, codeine syrup may be useful for cough associated with bronchospasm. In this case, it is prescribed alone or in combination with bronchodilators, anti-inflammatory and antihistamines.

Attention! To choose the right antitussive, the disease that caused the cough must be identified. The doctor must also take into account its intensity, duration, productivity and degree of influence on the patient’s well-being. It is advisable to assess the presence or absence of bronchospasm, viscosity, quantity and nature of sputum (mucous, purulent).

Contraindications

Codeine is contraindicated in cases where respiratory depression is not appropriate. Absolute contraindications include:

• severe respiratory and heart failure;
• bronchial asthma;
• hypersensitivity to the components of the drug;
• pneumonia;
• airway obstruction;
• alcohol or drug intoxication;
• pseudomembranous colitis caused by taking antibiotics;
• severe arterial hypertension;
• severe dysfunction of the liver and kidneys.

Codeine is contraindicated by age and is not used to treat children under 2 years of age. The effect of the drug on the course of pregnancy has not been fully studied. Its use is allowed for health reasons, when the benefits of use significantly outweigh the potential harm. It is prescribed with caution to children, elderly and weakened people.

What is it incompatible with?

It is important to avoid drinking alcohol during treatment with a codeine-containing drug.

Concomitant use with muscle relaxants, sedatives and opioid analgesics should be avoided due to enhanced effects and a high risk of critical respiratory depression.

In combination with antidiarrheals, the drug causes intestinal obstruction, with MAO inhibitors - inhibition or excitation with hypo- or hypertensive crises. Codeine also reduces the effect of the antiemetic drug Metoclopramide.

Names of drugs containing codeine

Medicines containing codeine are available in the form of tablets and syrups. List and brief description of antitussives.

1. Kofex (India). Dosage form – syrup. The drug contains 10 mg codeine and 4 mg chlorpheniramine maleate per 5 ml. Prescribed for dry paroxysmal cough with allergies and upper respiratory tract infections. Cofex is contraindicated for children under 12 years of age. The average duration of treatment is 3 days.

2. Terpinkod (Russia). Available in tablets. One tablet contains 8 mg codeine, 250 mg terpin hydrate and 250 mg sodium bicarbonate. It has both an expectorant and antitussive effect and is prescribed for severe dry cough. Children are prescribed from the age of 12 years.

It has antitussive, antipyretic, vasoconstrictor and analgesic effects.

The indication for taking the drug is a dry, debilitating cough that occurs against the background of influenza, respiratory infections, and is accompanied by a runny nose and fever. It is prescribed to children starting from 2 years of age.

4. Kodarex (India). Medicinal syrup for the symptomatic treatment of irritating dry cough of an allergic or infectious nature. Available in 60 ml bottles. The codeine content in 5 ml of syrup is 10 mg.

The medicine contains another active ingredient - chlorpheniramine maleate, which has an antiallergic, moderate sedative and expectorant effect. Kodarex can be used to treat children 6 years of age and older.

5. Kodesan IC (Ukraine). Combined antitussive drug. Dosage form: tablets. In addition to 9.5 mg of codeine phosphate, the Codesan tablet contains plant extracts of Thermopsis, Licorice and sodium bicarbonate. Indications for use are various diseases of the upper respiratory tract, accompanied by a dry, unproductive cough. The drug is approved for use by children over 12 years of age.

6. Tedein (Vietnam). Available in tablet form in strips of 10 pieces. Each tablet contains 8 mg codeine and 100 mg terpin hydrate.

The medicine suppresses cough and has an expectorant effect. It is used for dry paroxysmal cough of any etiology: inflammatory, infectious, allergic. Allowed for children from 6 years of age.

The duration of treatment with Tedein cannot exceed 5 days.

Doses

The dosage of a codeine-containing drug and the duration of treatment should be selected individually, according to the age and diagnosis of the patient. The maximum permissible dose for an adult is 120 mg of the substance per day. It is recommended to take the medicine after meals, 4 times a day. On average, for cough, take 10-20 mg of codeine 4 times a day with an interval of 6 hours.

What can be replaced?

There is more than one review on the Internet where codeine syrup is praised for a dry, debilitating cough. Indeed, the effect of taking it is noticeable almost immediately. But since 2012, the free sale of the drug has been prohibited, so many are wondering if there are any analogues? Yes, such antitussives exist, and moreover, they are available without a prescription.

Along with narcotic substances that suppress the cough center, there are non-narcotic ones. These include:

• butamirate citrate;
• libexin;
• oxaladine;
• prenoxdiazine;
• glaucine hydrochloride.

For example, many have heard the name of the drug Broncholitin. This is an antitussive containing glaucine, which suppresses cough, but unlike codeine, does not affect the respiratory center and does not cause addiction.

It is prescribed for dry cough of various etiologies: influenza, acute and chronic bronchitis, infectious and inflammatory diseases of the upper respiratory tract.

For the treatment of children, Bronholitin is used no earlier than the age of 4 years.

List of non-narcotic analogues:

• Sinecode;
• Panatus forte;
• Libexin;
• Paxeladine;
• Glauvent.

Dextromethorphan analogue

Dextromethorphan in its composition and action is most similar to codeine.

It is also a derivative of morphine and in high dosages causes a narcotic effect, and with regular use - psychological dependence.

Preparations containing dextromethorphan are used to suppress cough, in the treatment of heroin addiction, chronic non-degenerative diseases, Parkinson's disease, and mental retardation.

A number of syrups and cough tablets with dextromethorphan are produced in Russia:

• Tussin Plus;
• Glycodin;
• Zedex;
• Vokasept;
• Stopex.

All of the above drugs belong to list B, that is, it is assumed that a prescription is required to purchase them. But de facto, every second pharmacy sells Tussin syrup absolutely freely.

In conclusion, drugs containing codeine belong to a serious group of drugs and are prescribed only by a doctor. To purchase medicine at a pharmacy you need a prescription.

The consequences of incorrect administration or dosage calculation can be extremely serious, from severe constipation to pneumonia, acute respiratory failure and coma.

Source: https://OrviStop.ru/kashel/kodein.html

Common codeine-containing medications. Reference

• Currently, codeine-containing drugs are included in the list of drugs available without a doctor’s prescription, approved by Order of the Ministry of Health and Social Development of the Russian Federation dated September 13, 2005 No. 578.
• Inexpensive drugs containing codeine are purchased by drug addicts for the production and sale of desomorphine (a hard drug that is highly addictive and highly toxic).
• Combined analgesics
• "Pentalgin-N".
• One tablet contains 8 mg codeine (base).

Prescribed for moderate pain syndromes: toothache and headache, myalgia, arthralgia, radiculitis, neuralgia, etc.

; feverish conditions, colds and other diseases accompanied by pain and inflammation.

May cause side effects: on the nervous system and sensory organs - dizziness, drowsiness; on the part of the cardiovascular system and blood - impaired hematopoiesis; from the gastrointestinal tract (GIT) - nausea, vomiting, constipation, erosive and ulcerative lesions of the GIT, allergic reactions - skin rash, itching, urticaria. Long-term use may result in impaired renal function.

1. In case of overdose, nausea, vomiting, stomach pain, tachycardia, arrhythmia, and respiratory depression are observed.
2. Solpadeine
3. One tablet contains 8 mg of codeine (in the form of codeine phosphate hemihydrate).
4. The medicine is used for pain syndrome (headache, rheumatic pain, toothache, migraine, menalgia (menstrual pain), neuralgia, lumbago (acute lower back pain), traumatic pain, pain with sprains), sinusitis (inflammation of the paranasal sinuses), fever (sharp increase in body temperature), colds and flu.
5. Side effects are possible when taking the medication: nausea, vomiting, dizziness, insomnia, nervous agitation, constipation, allergic reactions (skin rashes).

An overdose of the drug may cause complications in patients with non-cirrhotic liver disease. Symptoms: pallor, nausea, vomiting, anorexia, abdominal pain, signs of circulatory and respiratory depression, tremor (shaking), nervousness, irritability.

• Nurofen Plus
• One tablet contains 10 mg of codeine (in the form of codeine phosphate hemihydrate).
• The drug is used for headaches and toothaches; migraines; painful menstruation; neuralgia; back pain, muscle and rheumatic pain; feverish state with influenza and colds.

In case of long-term use of the drug, nausea, vomiting, heartburn, anorexia, discomfort in the epigastrium (part of the abdominal cavity below the chest bone), diarrhea, flatulence (excessive accumulation of gases in the intestines), impaired liver function, abdominal pain (abdominal pain) may occur. , exacerbation of gastric ulcer, headache, dizziness, hearing loss, tinnitus, insomnia, agitation, drowsiness, depression, heart failure, increased blood pressure, tachycardia, edema syndrome, renal dysfunction, hematopoietic disorders, skin rash, itching, urticaria, Quincke's edema, bronchospasm, respiratory depression, suppression of the cough reflex, increased sweating. With long-term use (in large doses) - ulceration of the mucous membrane of the gastrointestinal tract, bleeding (gastrointestinal, gingival, uterine, hemorrhoidal), visual impairment.

1. An overdose of the drug causes abdominal pain, nausea, vomiting, lethargy, drowsiness, depression, headache, tinnitus, metabolic acidosis (the most severe form of acid-base imbalance in the body), coma, acute renal failure, decreased blood pressure, bradycardia (very low heart rate), tachycardia, atrial fibrillation, respiratory arrest.
2. "Caffetin"
3. One tablet contains 10 mg codeine phosphate sesquihydrate.
4. Indications for use are headache, toothache, migraine, neuralgia, sciatica, myalgia, dysmenorrhea, colds, flu, postoperative and post-traumatic conditions.

May cause side effects: nausea, pain in the epigastric region, increased excitability (especially in children), impaired hematopoiesis, allergic reactions (skin rash, itching, urticaria, Quincke's edema). With long-term use in high doses, it causes liver dysfunction.

• "Sedalgin-Neo"
• One tablet contains 10 mg of codeine phosphate.
• Prescribed for neuralgia, neuritis, migraine, pain (headache, dental, rheumatic, phantom, post-burn, traumatic, postoperative), colds accompanied by pain and hyperthermia; dysmenorrhea (menstrual disorder).

Long-term use of the drug can cause impaired renal and liver function, as well as attacks of bronchial asthma. If you suddenly stop taking the drug, withdrawal symptoms may appear, in this case headache predominates. With long-term use of large doses, resistance to some of the drug's effects may occur.

1. Antitussive tablets
2. "Codelac"
3. One tablet contains 8 mg codeine.

Prescribed for coughs of various etiologies. Side effects of the drug on the nervous system and sensory organs - headache, drowsiness; from the gastrointestinal tract - nausea, vomiting, constipation. Allergic reactions are possible.

Terpincode

One tablet of the drug contains 8 mg of codeine.

Used for cough. May have side effects: nausea, vomiting, constipation, headache, drowsiness.

Codterpin

One tablet contains 15 mg of codeine.

Used for cough. May have side effects: constipation, physical dependence with prolonged use.

Source: https://ria.ru/20110624/392787953.html

Where is codeine contained - composition of drugs

Codeine is a substance found in many medications.

For decades, the drug has been actively used in medicine to relieve attacks of dry cough and as a pain reliever.

Currently, drugs containing codeine are prohibited for free sale due to the discovered psychotropic effects of the drug on the human body. Next, we will tell you which medications contain codeine.

Effects of codeine on the body

The main effect of codeine is aimed at eliminating coughing attacks. Moreover, it is immediately worth noting the fact that the substance does not treat the disorder, but only removes its symptoms.

This fact is explained by the effect of codeine on parts of the human brain.

Thus, when taking the drug, pain receptors are blocked, which leads to an additional analgesic effect and improvement in the condition of colds.

The use of codeine causes stimulation of opiate receptors in the central nervous system. In the case of taking a minimum dose of the drug, a gentle effect on the functional activity of the peripheral nervous system is achieved.

When using a dosage that significantly exceeds the permissible levels, the drug has a narcotic effect on the human body. In this case, the patient experiences euphoria and excessive relaxation.

Brief loss of consciousness may also occur.

Effect of tablets that contain codeine

Codeine-based drugs can be produced in the form of tablets, syrup or drops. But the most common form of release is considered to be the first.

The effect of the drug can be aimed at eliminating headaches and toothaches, as well as discomfort after surgery or injury. But in this case, codeine should be part of the tablets, which additionally contain paracetamol or aspirin.

The effect of taking such a medication will become noticeable within a few minutes after using the drug and will persist for a long time.

In addition to these effects, the medicine is also a sedative, so after using it, the patient is not recommended to engage in activities that require concentration (for example, stop driving a car) for several hours.

What medications contain codeine?

Before answering this question, it is worth saying that the use of this drug must necessarily be agreed with a doctor, since the medicine has not only a therapeutic, but also a narcotic effect.

Moreover, in any case, it will not be possible to bypass this step, since due to its psychotropic effect on the body, the substance can only be purchased with a prescription from a specialist. Here is a list of drugs that contain codeine.

Codelac

One tablet of the drug contains codeine (8 mg), thermopsis grass in powder, sodium bicarbonate and licorice root. The use of the drug is indicated for acute coughing attacks of various etiologies.

The product thins mucus and promotes expectoration. The effect lasts up to 12 hours.

Side effects of the drug include headache, drowsiness, digestive system disorders and allergic reactions.

One tablet of the drug Terpincode contains codeine (8 mg), terpin hydrate and sodium bicarbonate. The medicine is prescribed to reduce coughing attacks and also as an expectorant.

Recommended for use in cases of respiratory pathologies. Side effects of the medication include nausea and vomiting, problems with bowel movements, allergic reactions, and headache. The positive effect lasts for 6 hours.

The course of therapy should not exceed 5 days.

Solpadeine

Solpadeine contains 500 mg of paracetamol, 8 mg of codeine phosphate hemihydrate and 30 mg of caffeine. Belongs to the group of analgesics and antipyretics.

It is an antitussive medication. Prescribed for adults and children over 12 years of age. The duration of use should not be more than 3 days.

The development of side effects can occur in all organ systems.

Tetralgin

Contains 8 mg of codeine in one tablet, excipients - caffeine, metamizole sodium and phenobarbital. Tetralgin is used for headaches, toothaches, myalgia, neuralgia and ARVI. Side effects include dizziness, tachycardia, digestive disorders, allergic rashes and increased drowsiness.

Nurofen Plus

1 tablet of the drug contains 12.8 mg of codeine phosphate hemihydrate and 200 mg of ibuprofen. The drug has an antitussive, analgesic, anti-inflammatory, antipyretic and analgesic effect. The medication has a large list of side effects, so the medication must be used within a short time.

Panadeine

The drug contains 8 mg of codeine phosphate and paracetamol in its composition. Indications for use include headache, migraine, neuralgia, toothache, arthritis, fever, colds and flu. Taking the medication in doses exceeding the permissible limits may cause the formation of allergic rashes.

One tablet of Kodarin contains 10.9 mg of codeine phosphate, as well as 250 mg of terpin hydrate and 250 mg of sodium bicarbonate.

The medication is usually well tolerated by patients and only in rare cases leads to the development of allergic reactions, pain in the gastrointestinal tract, surges in blood pressure and difficulty breathing.

Which drug contains more codeine?

The most codeine is contained in the drug Codipront. The medication is available in the form of syrup (5 ml of syrup - 11.1 mg) or capsules (30 mg of codeine). The product also contains phenyltoloxamine, which has a sedative and anti-allergenic effect.

The use of the medicine helps eliminate cough for a period of 12 hours. The drug is indicated for influenza, bronchitis, various infectious diseases, as well as for diseases of the upper respiratory tract. Side effects of the medication include increased drowsiness, fatigue, irritability, headache, blurred vision and problems with urination.

Possible contraindications

Drugs that contain codeine even in minimal quantities have similar contraindications. Thus, medications are prohibited for use by young children under 2 years of age, pregnant and lactating women, elderly people, professional athletes and patients suffering from alcohol addiction.

Also, you should not take codeine-based products if you have the following pathologies:

• allergy to medication components
• brain injury or cerebrovascular accident
• serious mental disorders
• respiratory pathologies
• thyroid disease
• presence of gallstones
• renal and hepatic colic
• ulcerative colitis
• prostate enlargement
• adrenal diseases
• low blood pressure
• Addison's disease, manifested by an insufficient amount of vital substances produced by the body

People suffering from impaired renal function should approach the treatment of abnormalities with codeine-containing drugs with special caution. Due to the slow elimination of the substance from the body, patients should increase the periods between taking the next dose of the drug.

Conclusion

To summarize, it is worth saying that codeine is a substance that is part of many antitussive and analgesic medications. The medicine also has a sedative and antidiarrheal effect.

Among the most common drugs with the addition of codeine are: Codelac, Terpincode, Solpadeine, Tetralgin, Nurofen Plus, Panadeine, Kodarin and Codipront.

But, despite the proven effectiveness of these products, they can only be purchased with a prescription from your doctor.

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