Anti-inflammatory drugs: use for prostatitis

• Anti-inflammatory drugs are one of the most popular areas in the pharmaceutical industry.
• Drugs in this category are effectively used in the treatment of injuries, inflammatory processes, and acute chronic diseases.
• Anti-inflammatory drugs with similar drug indicators differ in the way they affect the human body.

Kinds

There are two main groups of PVA:

• non-steroidal (non-hormonal) anti-inflammatory drugs (NSAIDs);
• non-hormonal, having anti-inflammatory, analgesic, antipyretic properties;
• steroidal (hormonal) anti-inflammatory drugs (SPVS).

Hormonal drugs are much more effective than NSAIDs, but their use can contribute to addiction. Use only as prescribed by a doctor and under his supervision.

Nonsteroidal (NSAIDs)

NSAIDs work by preventing the formation of substances called prostaglandins, which can cause fever, pain, and muscle cramps.

This task is achieved by blocking the enzymes cyclooxygenase types 1 and 2 (COX-1 and COX-2). It is with their help that prostaglandin is produced.

NSAIDs are safer and more versatile than NSAIDs, but they have one drawback - they block COX 1, with the help of which substances are formed that prevent the destruction of the gastric mucosa, which is affected by hydrochloric acid present in the gastric juice.

Due to the development of modern pharmacology, selective NSAIDs have been improved. Modern NSAIDs only block COX-2. And, unlike SPVA, they do not have a hormonal effect. Thus, NSAIDs began to be divided into two categories: non-selective and selective.

NSAIDs are widely used in the treatment of many diseases, the main of which are:

• arthrosis;
• rheumatoid arthritis;
• osteochondrosis;
• lower back pain;
• headache;
• migraine;
• acute gout;
• dysmenorrhea (menstrual pain);
• bone pain caused by metastases;
• moderate pain due to inflammation or soft tissue injury;
• postoperative pain;
• pain in Parkinson's disease;
• fever (increased body temperature);
• intestinal obstruction;
• renal colic;
• prostatitis.

Non-steroidal drugs, just like NSAIDs, have a list of contraindications, including:

• stomach ulcer;
• duodenal ulcer;
• kidney disease (in some cases, limited use of NSAIDs is allowed);
• increased or decreased blood clotting;
• pregnancy period;
• period of breastfeeding;
• allergic reactions of the patient’s body to this group of drugs.

In addition, side effects are possible, expressed in the form of changes in blood flow and inflammation or irritation of the stomach walls.

Due to the presence of side effects and a list of contraindications, the use of NSAIDs is allowed only as prescribed by a doctor.

Non-selective

Non-selective NSAIDs are outdated drugs that have a harmful effect on the gastrointestinal tract by neutralizing COX-1.

Non-selective NSAIDs are derivatives of acids:

• acetylsalicylic acid – Aspirin and its varieties, Diflunisal, Salasat;
• arylpropionic – Ibuprofen, Flurbiprofen, Naproxen, Ketoprofen, Tiaprofenic acid;
• anthranilic – Flufenamic and Mefenamic acids;
• arylacetic – Diclofenac, Fenclofenac, Fentiazac;
• heteroaryl acetic acid – Ketorolac, Amtolmetin;
• methanesulfonic – Analgin;
• indole/indene acetic acid – Indomethacin, Sulindac;
• enolic, in particular oxicams - Piroxicam, Tenoxicam, Meloxicam, Lornoxicam.

Selective

Selective NSAIDs are modern medical drugs that act only on COX-2, allowing COX-1 to release substances that prevent the destruction of the gastric mucosa.

Selective NSAIDs are:

• lumiracoxib – Prexige;
• parecoxib – Dynastat;
• rofecoxib – Denebol;
• celecoxib – Celebrex;
• etoricoxib - Arcosia.

Anti-inflammatory drugs in urology in men

Drugs with anti-inflammatory effects in the treatment of urological diseases in men are used in the following cases:

• urethritis;
• prostatitis;
• cystitis;
• urolithiasis disease;
• balanoposthitis.

One of the common diseases that requires the use of NSAIDs is prostatitis. This disease is caused by inflammation of the prostate gland due to infection, hypothermia, stress, sedentary lifestyle and decreased immunity.

Non-steroidal anti-inflammatory drugs are widely used in tandem with antibiotics for prostatitis. NSAIDs for prostatitis are used to weaken the body’s reverse reaction to the onset of the pathological process, as well as to combat chronic inflammation characteristic of this disease.

Using anti-inflammatory drugs for prostatitis, it is possible to achieve positive results within a few hours, namely:

• mitigation or complete relief of pain;
• normalization of body temperature;
• restoration of normal urination;
• improving the general well-being of the patient.

Solution for injection Diclofenac

Anti-inflammatory drugs for prostatitis, which are most often used as primary treatment:

• Diclofenac;
• Ibuprofen;
• Ketoprofen.

It is preferable to use Diclofenac-based NSAIDs, since they have less pronounced side effects.

Additionally, auxiliary medications are used:

• Thiotriazolin;
• propolis;
• Ichthyol;
• Prostatilen;
• sea ​​buckthorn oil.

Suppositories and solution for injection Prostatilen

The above anti-inflammatory drugs for prostatitis most effectively affect the body when taken in the form of suppositories. But in some cases, oral administration is allowed.

Anti-inflammatory drugs are mandatory for chronic prostatitis. In addition to all the above drugs, Indomethacin is used for the chronic nature of the disease. It effectively copes with the symptoms of the disease, but has a large number of various contraindications. Therefore, Indomethacin is prescribed only in emergency situations.

Suppositories Indomethacin

In addition to drugs from the NSAID group, other drugs are also prescribed for the effective treatment of chronic prostatitis:

• antibiotics: Moxifloxacin, Gemifloxacin, Levofloxacin;
• alpha blockers : Alfuzosin, Finasteride, Artesin;
• vitamins.

Ketorol (ketorelacotromitamine) shows good results in the treatment of prostatitis. But it contains potent substances and has a very intense effect on the body, so it cannot be used without a doctor’s recommendation.

Steroids (SPVA, SPVP)on

Steroid PVAs are hormonal drugs that are superior to NSAIDs in terms of their effect on the body, but with prolonged use they are addictive. In addition, NSAIDs have a list of contraindications and strong side effects, therefore they are prescribed by doctors only in cases of special need.

The most common drugs:

• Cortisone;
• Maxidex;
• Dexamethasone Syn;
• Oftan-Dexamethasone;
• Prednisolone;
• Sinalar Sin;
• Berlicourt;
• Kenalog;
• Nazacort;
• Polcortolon;
• Triamsinolone;
• Flucinar;
• Fluorocort;
• Betamethasone.

The use of SPVA is effective in the treatment of systemic diseases and relief of symptoms in connective tissues and joints:

• arthritis;
• arthrosis;
• sarcoidosis;
• alveolitis

SPVA can also be used to treat the nose and throat and other non-infectious inflammatory processes in tandem with antibiotics.

Side effects caused by drugs of the SPVA group may depend on several factors: dosage, methods of administration and properties of the drug. With topical use of SPVA, a weakening of resistance to diseases may occur.

With systemic, constant use of the drug there is a risk of manifestation of the list of diseases:

• arterial hypertension;
• steroid gastric ulcer;
• steroid vasculitis;
• hypertrichosis;
• Cushing's syndrome;
• steroid diabetes;
• psychosis;
• potassium loss;
• myocardial dystrophy;
• osteoporosis;
• tuberculosis;
• water and sodium retention.

Contraindications for the use of SPVA are determined by the presence of the following symptoms and diseases:

• tuberculosis and other infectious diseases;
• osteoporosis, including during the postmenopausal period;
• tendency to thrombosis;
• diabetes;
• peptic ulcer of the duodenum and stomach;
• mental disorders;
• arterial hypertension;
• pregnancy period;
• the presence of an infectious process in the respiratory tract, as well as in the joints.

NSAIDs are medications that act at the hormonal level and have many side effects, as well as a list of contraindications. SPVA drugs can only be used as prescribed by a doctor and under the supervision of specialists.

Video on the topic

About anti-inflammatory suppositories for the treatment of prostatitis:

Anti-inflammatory drugs are effective drugs needed in modern medicine. They are able to improve the condition of the patient’s body in the shortest possible time. Like all medications, anti-inflammatory drugs have a list of limitations.

The main problem with the use of anti-inflammatory drugs is that often drugs of this type are perceived as a panacea for all diseases and are used without a doctor’s prescription.

This is dangerous because after eliminating the symptoms of the disease, a pseudo-sensation of recovery is created. But the cause of the symptoms is very likely not eliminated, and it may begin to progress, with serious consequences.

Source: https://prostata.guru/prostatit/lechenie/preparaty/protivovospalitelnye.html

Anti-inflammatory drugs for prostatitis: review of the most effective drugs, application, reviews

• October 15, 2018
• Prostatitis
• Natalia Kalinichenko

Prostatitis is a disease that is quite common in men. According to statistics, last year alone the number of diagnosed prostate pathologies increased by 15%. In men over the age of 20, this disease is diagnosed in 25%, and in men over the age of 40 – in 50%. It is clear that such a scale of the problem provokes the pharmaceutical industry to create more and more new drugs.

But this is not a reason to run to the pharmacy and buy all the anti-inflammatory drugs on the list. When dealing with prostatitis and its prevention, it is very important to reconsider your lifestyle. If the diagnosis has already been made, then you should strictly follow all the recommendations of the attending physician and regularly undergo routine examinations by a urologist.

Prostatitis is an inflammatory process in the prostate gland, which can occur due to various factors. The cause of the development of the disease can be a sedentary lifestyle, hypothermia, and weakened immunity. The disease itself can occur in acute or chronic form, even with general signs of intoxication of the whole body.

Therapeutic measures

Today there is a clear understanding of what inflammation of the prostate is and how to deal with it. Treatment measures include:

• use of anti-inflammatory drugs for prostatitis;
• physiotherapy;
• antibacterial treatment;
• gland massage;
• stimulation of blood circulation;
• use of antiviral and painkillers;
• sedative therapy.

How is the treatment carried out?

Particular importance is given to anti-inflammatory drugs for prostatitis. They allow you to rid the body of bacteria and reduce the inflammatory process, relieve pain and spasms.

In addition, such drugs are prescribed in cases where antibacterial therapy has had no effect, or the disease is of non-bacterial origin.

The main thing is for the patient to understand that it is not permissible to take such drugs on their own, since they “blur” the symptoms and do not allow a correct diagnosis.

Release form

Conventional and non-steroidal anti-inflammatory drugs for the treatment of prostatitis are available in the form of tablets, capsules, injections and suppositories for rectal administration.

However, most often drugs are prescribed in the form of suppositories, although their effectiveness for this type of disease is not very high.

This is due to the fact that the medicine has to penetrate not only the capsule of the gland, but also the intestinal wall. So why is this particular form prescribed?

In fact, although the active substance penetrates the gland with difficulty, it still penetrates and reaches the diseased organ. And most importantly, the suppositories do not affect the liver, therefore, the treatment does not have a detrimental effect on other organs.

Comparative characteristics

Most of this group of drugs is represented by non-steroidal anti-inflammatory drugs. With prostatitis, they help alleviate the patient’s condition, relieve the feeling of heaviness and eliminate itching.

The most popular non-steroidal drugs include:

Name	Indications	Release form	Action	Analogs	Contraindications
"Diclofenac"	Chronic and acute forms of the disease, especially if the course of the disease is complicated by an increase in body temperature.	Suppositories, tablets and injection solution.	Has an analgesic effect, relieves swelling and inflammation.	"Diklak", "Voltaren"	Not recommended for use in the presence of gastrointestinal pathologies or in old age. Completely incompatible with alcoholic beverages. Helps slow down the reaction.
"Keptophrene"	Pronounced pain.	Tablets, injection solution, capsules.	For acute pain, injections are administered, but the drug acts through a cumulative system.
"Ibuprofen"	Non-steroidal anti-inflammatory drug for chronic prostatitis. Use in acute forms of the disease is allowed.	Tablets, Rectal suppositories.	Eliminates the manifestations of swelling and stops the inflammatory process. It copes well with pain and even helps reduce body temperature.	"Ibunorm", "Caffetin"	This drug should be taken with great caution if you have bleeding disorders or problems with the heart muscle.
"Nimesulide"	Acute form of the disease and intolerance to Diclofenac or Ibuprofen.	Pills.	As a rule, it is very well tolerated by all age groups.	“Nise”, “Nimesil”, “Nimulid”.	People who have diabetes, heart problems, and hypertension should be more careful.
"Meloxicam"	Acute pain.	Injection form.	Can only be used in short courses of up to 5 days. Relieves pain quickly.	"Movalis", "Movasin", "Amelotex".	Not recommended for use for stomach ulcers and bronchial asthma.
Acetylsalicylic acid	Fever and high body temperature.	Pills.	Prescribed for feverish conditions, it can effectively relieve pain and fever.	It is not recommended to use it for bronchial asthma.

Medicine "Prostopin"

The list of the best anti-inflammatory drugs for prostatitis would not be complete without the presence of some drugs. In particular, Prostopin rectal suppositories. The drug helps strengthen the immune system and promotes the regeneration of prostate tissue. Recommended for use during the indolent form of the disease.

Product "Prostatilen"

This anti-inflammatory drug for prostatitis can be used at any stage of the disease. Available in the form of suppositories and dry substance for the preparation of solution for injection.

It copes well with stagnant processes and relieves swelling. In addition, the medicine improves sperm quality and has an antimicrobial effect.

Helps improve muscle activity of the gland and bladder.

The drug is administered twice a day if suppositories are used. If a solution is used, it should be diluted with saline or novocaine. The course of treatment is 7–12 days.

Sea buckthorn oil

These are anti-inflammatory rectal suppositories. For prostatitis they can be used at any stage. Perfectly restore and heal damaged tissues, stimulate the body's immune forces. They also have astringent properties and eliminate itching and discomfort.

Sea buckthorn oil can be used as microenemas in the treatment of prostatitis, from which it will be possible to achieve the fastest therapeutic effect.

The course of treatment is 10 days, which should be carried out monthly. However, suppositories with sea buckthorn oil, like microenemas, should not be used if you have cancer or diarrhea. As men who have used these suppositories say, despite the fact that the procedure for administering the suppositories itself is unpleasant, the effect of the medicine is observed already on days 4–5.

"Ichthyol candles"

These rectal suppositories are also recommended for use for any etiology of prostatitis. They restore local blood circulation well, relieve pain and swelling.

“Ichthyol” itself is perfectly absorbed through the mucous membranes and skin. It has a moderate irritant effect, which contributes to changes in tissue trophism. In addition, the drug allows you to normalize vascular tone, improve blood flow directly to the prostate and restore metabolic processes.

The course of treatment must be determined by the doctor; suppositories are administered daily, morning and evening.

"Ichthyol" can be used as an anti-inflammatory drug for prostatitis after a biopsy.

"Prostamol Uno"

This drug of plant origin has antiadrogenic activity and is an anti-inflammatory agent for prostatitis, which is part of complex therapy.

The drug has pronounced anti-edematous and vasoprotective properties. Allows you to reduce the permeability of the vascular wall. Recommended for use in the first and second stages of the disease.

It relieves severe pain well and allows you to cope with nocturnal pollakiuria.

The drug has no contraindications for use and is well tolerated by all age groups. However, it should be taken with caution if there is a tendency to allergic reactions, as there is a risk of developing sinusitis or rhinitis of an allergic nature.

"Vitaprost"

This drug is available in the form of suppositories for rectal administration and in tablet form. The drug has a pronounced anti-inflammatory effect for prostatitis.

It has an antibiotic base and, in addition to relieving inflammation, has antibacterial properties. Helps normalize the urination process and prevents the development of blood clots in the vessels of the prostate gland.

It also improves the quality of semen.

As a rule, this remedy is recommended for use after surgery or in the chronic form of the disease. The course of treatment is daily for 10 days. As patients say, if you combine Vitaprost and other recommended drugs, the effectiveness of the treatment is already visible on the 3rd day.

"Vitaprost Plus" is used mainly to treat the bacterial form of the disease, since it also contains levofloxacin. "Vitaprost Forte" can be used for chronic prostatitis, but with a limited period of treatment, since it is more intended for the treatment of adenoma.

"Cernilton"

Along with non-steroidal anti-inflammatory drugs, muscle relaxants are often used for prostatitis. They allow you to relax your muscles. Such drugs include “Cernilton” and “Cernilton forte”. These medications are widely used in the treatment of pathologies associated with the prostate gland: prostatitis and adenoma.

The drug helps eliminate swelling and improve metabolic processes, and as a result, cope with pain. By relaxing the muscles of the posterior urethra, it improves the process of urination and erectile function.

The drug is available in the form of tablets and capsules. The tablet form is used three times a day, two tablets. Capsules are also drunk three times throughout the day, but one piece at a time. Judging by the reviews, some patients treated with this drug observe improvements literally within 3–4 days from the start of treatment.

A little more about herbal preparations

The drug Permixon has a similar effect to Cernilton. It contains only one active ingredient - sabal palm extract. The medicine is available in capsule form and is taken once a day.

“Red Root Plus” is an alcoholic tincture of kopeck and knotweed. Take the medicine one teaspoon three times throughout the day. The medicine must be mixed with a small amount of water.

"Apiprost" is a product containing propolis and pollen. Available in capsule form.

"Veroprostan" is a herbal combination preparation with the following components:

• horse chestnut;
• bearberry extract;
• sabal palm fruits.

In addition, it contains selenium and zinc as auxiliary ingredients, which help normalize the functioning of the prostate gland. This drug is taken in the amount of 2 capsules once a day.

All of these drugs have an anti-inflammatory effect, but it is still not recommended to use them without a doctor’s recommendation. Do not forget that plant components can cause allergies and even harm the patient’s health.

Source: https://cureprostate.ru/418958a-protivovospalitelnyie-preparatyi-pri-prostatite-obzor-samyih-effektivnyih-sredstv-primenenie-otzyivyi

What anti-inflammatory drugs will help with prostatitis?

Treatment of prostatitis involves the use of several medications and additional means. Only with an integrated approach does a quick and complete recovery occur.

There are highly specialized groups of drugs and symptomatic medications. Since the disease is inflammatory in nature, the basis of therapy is anti-inflammatory drugs for prostatitis.

They help relieve inflammation and associated pain. What medications are we talking about, and how to use them?

Anti-inflammatory drugs for prostatitis

Features of anti-inflammatory treatment of prostatitis

Prostatitis is an inflammatory disease of the prostate gland, which occurs in acute or chronic form. It can be successfully treated conservatively using a special group of drugs. In most cases, it includes anti-inflammatory drugs that eliminate the inflammatory process and relieve pain.

For therapy, non-steroidal anti-inflammatory drugs (NSAIDs, NSAIDs) are usually used - a type of medicine that has an antipyretic, analgesic, and anti-inflammatory effect. The mechanism of action is to suppress the production of prostaglandins in the body, which are involved in the development of inflammation.

In acute prostatitis, there is severe pain in the groin, a burning sensation when urinating, an increase in body temperature and poor health due to general intoxication of the body. All these symptoms can occur suddenly and take a man by surprise. In this case, NSAIDs will provide immediate assistance:

• will reduce the intensity of the inflammatory process;
• reduce hyperemia of glandular tissue;
• will stop the proliferation of harmful microorganisms;
• normalize temperature;
• relieve fever;
• eliminate pain and spasms.

Funds from this group are available in various forms. For prostatitis, anti-inflammatory drugs are used in two main dosage forms:

Drugs for the treatment and prevention of prostatitis

• tablets - provide systemic and rapid assistance, absorbed into the blood through the gastrointestinal tract;
• suppositories - act locally and prolonged, penetrating through the walls of the rectum.

A suitable and effective drug should be selected by the attending physician based on the diagnosis and complaints of the patient. Self-administered one-time use as an emergency aid is allowed. Long-term self-medication is strictly prohibited.

Tablet anti-inflammatory drugs for prostatitis

Tablets for prostatitis are easy to use. You only need to drink one pill and in just 20–30 minutes you will experience significant relief.

They are very effective as an emergency aid for high fever and severe pain.

But there is one important nuance: with long-term use, there is a negative effect on the gastrointestinal tract and kidneys. Therefore, they are prescribed by a doctor according to a strict dosage regimen.

The most commonly used NSAIDs in urology are ibuprofen, ketoprofen, and diclofenac. They have the least number of side effects and the best anti-inflammatory effect.

The active substance is diclofenac sodium in an amount of 50 mg or 100 mg. It relieves heat and body aches well, reduces the intensity of the inflammatory process, and significantly reduces tissue swelling and pain.

Take 1 tablet no more than 3 times a day, preferably with meals (to reduce irritation of the gastric mucosa). The maximum dose per day should not exceed 150 mg.

Contraindicated for peptic ulcers and hematopoietic problems.

Dicloberl injections for prostatitis

Anti-inflammatory capsules based on ibuprofen, contain 300 mg of active ingredient. They have antipyretic, analgesic and anti-inflammatory effects. Dosage for adults: 1-2 capsules twice a day, no more than 4 capsules per day. Should not be taken if you have allergies, gastrointestinal pathologies, hematopoietic disorders, liver or kidney dysfunction.

NSAIDs from the ketoprofen group, a derivative of propionic acid. It is quickly absorbed into the gastrointestinal tract and has a long-lasting analgesic effect. Available in tablets and capsules of various concentrations.

The recommended dosage regimen involves 1 tablet 2 times a day after meals. A single application is sufficient to relieve an acute attack.

Long-term use may cause abdominal pain, dyspepsia, nausea, headache, bleeding, hearing and vision impairment.

Anti-inflammatory medications should not be overused to avoid serious adverse reactions. Long-term therapy for prostatitis should be carried out under the strict supervision of a physician. All recommendations and prescriptions must be followed.

Anti-inflammatory drugs for the prostate in the form of suppositories

Urologists prefer to prescribe suppositories for rectal administration to men.

They have a number of important advantages: they act directly at the injection site, penetrate into the prostate tissue, do not have a negative effect on the body, including the gastrointestinal tract, and have a long-lasting effect.

At the same time, there is a significant disadvantage - suppositories are not able to quickly relieve inflammation, because they have to overcome many barriers to dissolution. Experts note that this form of anti-inflammatory drugs is effective for long-term and systemic therapy.

Rectal suppositories for prostatitis

Prostatitis suppositories may contain several components that not only relieve inflammation, but also improve blood circulation, destroy bacteria, promote tissue regeneration, relieve pain, and restore urination. The combination drug may contain:

• antibiotic;
• analgesic;
• thiotriazoline;
• prostapine;
• prostilen;
• sea ​​buckthorn oil;
• propolis.

The most popular drugs are:

Suppositories for rectal administration based on diclofenac. Absorbed through the intestinal tissue, penetrating directly into the inflamed gland. The analgesic effect occurs approximately an hour after administration.

Directions for use: one suppository in the morning and evening is inserted into the anus as deeply as possible until completely dissolved. No more than 150 mg of active substance is allowed per day. It is effective to combine tableted Voltaren with suppositories.

In this case, it is recommended to administer the suppository only at night. The rectal form should not be used for proctitis or hemorrhoids.

Prostopin rectal suppositories, 15 pcs.

Belongs to the group of drugs – phytoprostate protectors. These are candles based on natural ingredients: propolis, bee bread, honey, royal jelly.

It has a pronounced anti-inflammatory and antioxidant effect, normalizes the process of urination, destroys pathogenic microflora, and prevents prostate hyperplasia. The suppository is administered once a day before going to bed.

The duration of the treatment course is at least 2 weeks. Side effects occur rarely, usually in the form of skin allergies in the perianal area.

A product containing prostate extract and the antibacterial component lomefloxacin.

As a result of use, inflammation and swelling are eliminated, bacteria are destroyed, pain is reduced, and the composition of prostatic secretion improves.

Anti-inflammatory suppositories for prostatitis have proven their effectiveness in practice, therefore they are often prescribed as one of the components of the treatment of acute and chronic pathology in men.

Additional anti-inflammatory drugs for the prostate

NSAIDs alone cannot cure prostatitis. Chronic pathology is often accompanied by a bacterial process, which can be stopped exclusively with the help of antibiotics. And the acute form is manifested by strong and painful symptoms, which must be alleviated with medications. A comprehensive treatment regimen for prostate inflammation may include:

• antibiotics - have a powerful bactericidal effect, destroying the pathogenic microflora of the gland (Ciprofloxacin, Amoxiclav, Levofloxacin);
• analgesics and antispasmodics - relieve pain and eliminate spasms of muscles and sphincter (Nurofen, Drotaverine, Buscopan);
• alpha-blockers – facilitate urination and urine outflow (“Doxazosin”, “Tamsulosin”, “Omnic”);
• muscle relaxants - relieve tension in the gland, reduce pain (Diazepam, Baclofen, Mydocalm);
• hormones – restore the hormonal balance and sexual power of a man (“Omnadren”, “Flutamide”);
• herbal medicines are auxiliary natural remedies, so-called dietary supplements (“Prostamol Uno”, “Tandenan”, “Tykveol”).

A successful and rapid recovery is impossible without additional physical procedures, diet and a healthy lifestyle, moderate activity and good mood. Follow all doctor's orders, take prescribed medications correctly and be healthy!

Source: https://prostatoff.ru/prostatit/protivovospalitelnye-preparaty-pri-prostatite

Anti-inflammatory drugs for prostatitis

Prostatitis is an inflammation of the prostate tissue. The disease includes many symptoms, differing in causes and manifestations in men of different ages. However, they are all united by the inflammatory process.

Nonsteroidal anti-inflammatory drugs (NSAIDs)

They are used to relieve pain, burning and itching, and relieve fever. Taking NSAIDs also helps improve urination and reduce heaviness in the lumbar region.

The principle of operation of drugs in this group is that the drug blocks the immune response to the inflammatory process occurring in the prostate gland, reducing it.

 Indications for use:

• Insufficient effectiveness of antibacterial therapy in the complex treatment of acute forms of prostatitis;
• Nonbacterial etiology of the disease;
• Chronic prostatitis in the period of exacerbation;
• Severe pain and discomfort in the area of ​​the prostate, as part of the symptomatic treatment of prostatitis of any type and complexity.

Non-steroidal drugs for prostate inflammation are also indicated in the treatment of prostate adenoma.

Effective NSAIDs 

Suppositories for rectal use are considered especially effective in relieving inflammation and pain due to prostate disease.

Ibuprofen

A drug that provides symptomatic treatment of prostate inflammation. Used as therapy for chronic prostatitis. Effectively reduces inflammation of prostate tissue and relieves pain. You need to take ibuprofen 400-800 mg 2-3 times a day. The amount of the drug taken at a time depends on the strength of the pain syndrome. The medicine has a number of contraindications:

• Arterial hypertension, cardiac dysfunction;
• Gastritis, colitis, gastrointestinal ulcers;
• Disorders of the vestibular apparatus;
• Failure of the liver or kidneys, liver cirrhosis.

In general, Ibuprofen is well tolerated and has relatively low toxicity, which makes it available for widespread use. This is also facilitated by the fact that the production of this medicine is currently established in Russia, due to which its price is much lower.  

 Diclofenac

One of the most effective medications. It includes a huge range of diseases in its list of indications, and is also well suited for the treatment of the prostate. Relieves pain and swelling. An important plus is that it is inexpensive: its average price is 60 rubles.

Diclofenac tablets 50 mg are taken 1 piece 2-3 times a day. The maximum daily dose is 150 mg. Due to the considerable toxicity of the drug and the likelihood of side effects, it is not recommended to exceed the dosage.

Side effects of Diclofenac include:

• Bleeding in the gastrointestinal tract;
• Headache, drowsiness or insomnia, depression, psychotic states;
• Impaired hearing, vision, taste;
• Increased blood pressure, heart rate, prospects for the development of myocardial infarction;
• Disturbances in the process of hematopoiesis.

If the patient has a tendency to thrombosis, taking the drug is strictly contraindicated due to the thromboembolic effect of Diclofenac.

Aspirin

Acetylsalicylic acid is aspirin, a drug known to many and tested by numerous studies. The medicine is suitable for people prone to arterial hypertension or heart disease. Aspirin does not lead to the formation of blood clots, but, on the contrary, helps thin the blood.

It is worth considering that the drug also has a number of strict contraindications:

• Kidney diseases;
• Bleeding disorders, hemophilia;
• Bronchial asthma.

The use of Aspirin in patients with gastritis or mild diabetes requires prior consultation with a doctor.

Ketoprofen

It has a cumulative property and gives a pronounced anti-inflammatory effect after 5-7 days of therapy. Ketoprofen is taken 1 tablet 100 mg 1-2 times a day. The maximum daily dose of the drug is 200 mg.

Side effects:

• Nausea, flatulence;
• Increased irritability;
• Arterial hypertension, worsening of already developed pathologies in the heart, decrease in red blood cells;
• Pharyngitis, rhinitis;
• Renal dysfunction;
• Rash, eczema, urticaria.

 When treating, you need to take into account that taking Ketoprofen can hide the symptoms of viral diseases in the body.

Nimesulide

The medicine has high and rapid activity, the effect of the drug occurs within 5-10 minutes. Nimesulide can relieve pain, as well as reduce redness and swelling. The drug is not suitable for the treatment of chronic inflammation of the prostate gland due to its high hepatotoxicity.

The medicine is taken once a day, 100 mg. To do this, the powder is diluted in 100 ml of water to form a suspension, and then drunk. You can divide the intake of 100 mg of powder into 2 times. The maximum daily dose is 200 mg.

Contraindications to the use of Nimesulide are:

• Erosive and ulcerative lesions of the gastrointestinal tract;
• Liver and kidney failure;
• Temperature above 38.5 caused by ARVI;
• High blood pressure, cardiac dysfunction.

 Nonsteroidal anti-inflammatory drugs (NSAIDs), as a rule, form part of the treatment of any form of prostatitis, however, uncontrolled self-administration of drugs from this group is unacceptable.

Additional remedies for the treatment of prostatitis

In the symptomatic treatment of the disease, it is possible to use additional drugs of plant or animal origin. The big advantage of this treatment is the absence of contraindications except for individual intolerance to the components.

Ichthyol

The drug is made from the resin of rock trees. Characterized by analgesic and antiseptic effects. A special feature of the drug is that it has a beneficial effect on the mucous membrane, normalizing peripheral blood circulation in the human body and restoring vascular tone.

Ichthyol is used rectally, 1-2 suppositories per day.

Sea buckthorn oil

It can accelerate tissue regeneration and has a pronounced anti-inflammatory effect.

The drug is used for inflammation of the prostate gland rectally through microenemas, 0.5 g 2 times a day.

Prostopin

A medicine based on propolis and royal jelly. The effect of the drug is due to antibacterial, regenerative, antiseptic and antitumor properties, which together provide an anti-inflammatory and analgesic effect.

Prostopin is used rectally, 1 suppository 1 time per day, at night.

Prostatilen

The drug is a peptide complex isolated from the bovine prostate. Acts directly on the prostate gland, reducing stagnation of secretions and helping to reduce its swelling. The drug is administered intramuscularly at a dose of 5-10 mg 1 time per day along with a solution, the composition of which is specified by the doctor.

Symptomatic treatment is an integral part of the treatment of prostate disease. Relieving inflammation and pain plays an important role in productive recovery. To consolidate the therapeutic effect, taking NSAIDs is often indicated along with taking antibiotics.

Reviews

Lysov Alexey

For those who suffer from chronic pain, I highly recommend trying Ibuprofen. The risk of side effects is relatively low compared to the other options described here, and the effect is good.  

Paltovich Igor

I use Ketoprofen. During chronic exacerbations of the disease, it relieves swelling and pain well. True, I try not to get carried away, like with any other medications, in principle.

Rybin Alexander

Diclofenac copes well with severe swelling and takes away the pain in one or two minutes; it’s an effective remedy, to say the least. But, as Igor writes, I also try not to get carried away. It is important to stick to the dosage and see a doctor, then everything will be fine.

Video on topic

  Prostopin - suppositories for the treatment of prostatitis and hemorrhoids

Source: https://chlena.ru/prostata/protivovospalitelnye-preparaty-pri-prostatite.html

Review of anti-inflammatory drugs for prostatitis

Prostatitis is an inflammation of the prostate gland that occurs for various reasons. For successful treatment of the disease, drugs with an anti-inflammatory effect should be used as part of complex therapy.

In the case of prostatitis, nonsteroidal anti-inflammatory drugs (NSAIDs) are prescribed, which can not only relieve inflammation, but also relieve pain. We will talk about their action, varieties and features of reception in the article.

How do anti-inflammatory drugs work for prostatitis?

With certain disorders, inflammation begins in the prostate gland. Most often, it is caused by bacterial activity or tissue damage, such as stones. At the same time, the body activates COX - special enzymes that promote the production of prostanoids. Some of them stimulate inflammation and are the true cause of pain in the prostate gland.

Nonsteroidal anti-inflammatory drugs prescribed for prostatitis suppress the activity of COX, thereby helping to reduce the intensity of inflammation and relieve pain. As a result, the patient feels relief, depending on the drug, an hour or two after taking it or even earlier.

Some NSAIDs prescribed for the treatment of prostatitis have a negative effect on the liver and gastrointestinal mucosa and cause swelling of various locations, and therefore the course should be monitored by a doctor.

Non-selective and selective drugs for prostatitis

Steroid anti-inflammatory drugs can affect hormonal levels, are often addictive, and therefore are practically not prescribed for prostatitis. Non-steroidal drugs have become much more widely used. Based on the principles of their effect on COX-1 and COX-2, these drugs are divided into two groups: selective and non-selective.

Non-selective drugs

Medicines in this group are capable of inhibiting two enzymes at once - COX-1 and COX-2. They have both analgesic and anti-inflammatory effects, and some of them can eliminate fever. The most famous remedies belonging to this group are:

• Indomethacin;
• Diclofenac;
• Piroxicam;
• Ibuprofen;
• Aspirin.

At the beginning of the list are stronger drugs, at the end - the effect of which is weaker. But all of them are prescribed by a doctor for the treatment of acute prostatitis and exacerbations of the chronic form. In addition, Diclofenac has antitumor properties, and therefore can be prescribed for congestive forms of prostatitis.

Non-selective drugs have many side effects, disrupt the integrity of the mucous membranes of the stomach and intestines, and can negatively affect the liver.

Selective drugs

New generation agents that act more selectively in relation to COX. Some of them inhibit primarily COX-1, while others act primarily to suppress COX-2. This mechanism of action contributes to better tolerance by the body, but the drugs are practically not used in urology.

The most famous drugs in this group:

• Celecoxib;
• Nimesulide;
• Meloxicam;
• Dynastat;
• Etoricoxib.

For prostatitis, these drugs are prescribed much less frequently. However, if the doctor recommends taking them, there is no need to refuse.

Unfortunately, it is not yet possible to achieve 100% selectivity, because there is a possibility of side effects, although not as high as in the case of non-selective agents.

Indications and contraindications

Nonsteroidal anti-inflammatory drugs can be prescribed for damage to joints, bone and muscle tissue, toothache, some neurological disorders, as well as infectious processes. In male urology, these drugs are used for the following diseases:

The main purpose is symptomatic therapy and the fight against inflammation. However, NSAIDs should be used only as part of complex therapy, in combination with antibiotics and drugs from other groups.

When prescribing anti-inflammatory drugs for prostatitis, the doctor takes into account side effects, as well as the likelihood of their occurrence. The last point is individual and depends on the patient’s health condition. Contraindications to treatment with these drugs are:

• erosion of the stomach or intestines;
• peptic ulcer of the stomach and duodenum;
• allergic reactions;
• severe renal and liver failure;
• internal bleeding or tendency to it.

The most common side effects are nausea, vomiting, stool problems, urination problems, changes in blood clotting, and dizziness. Some drugs can cause weakness, fatigue, and loss of strength. Possible disturbances in motor coordination and decreased concentration.

NSAIDs can affect the ability to drive vehicles and operate machinery, so the patient should not engage in these activities during treatment.

Interaction with other drugs

Prostatitis and prostate adenoma are often complicated by inflammatory processes in other organs, leading to deterioration of the kidneys, liver, and cardiovascular system, and therefore treatment must be comprehensive. In this situation, it is important to know which drugs are combined with anti-inflammatory drugs and which are not.

NSAIDs, selective and non-selective, interact with other drugs as follows:

• reduce the effect of diuretics;
• enhance the effect of antidiabetic drugs;
• increase the toxic effects of drugs prescribed to combat cardiovascular disorders, as well as some antibiotics.

For better penetration of active agents into the blood, an alkaline environment is needed.

It is important to carefully select drugs for complex therapy, keeping in mind the peculiarities of the interaction of anti-inflammatory drugs with them.

Dosage forms for prostatitis

In pharmacies you can find anti-inflammatory drugs in all forms - from injection solutions to creams and ointments. However, not all types are used in the treatment of prostatitis. Let's look at the most popular forms in descending order:

• rectal suppositories (suppositories) act quickly on the prostate, with fewer side effects;
• solutions for injections - help to quickly relieve inflammation in acute forms;
• tablets - used for long-term use in some cases.

For prostatitis, applying cream to the perineum is pointless. It is necessary to select the dosage form that will most effectively affect the area of ​​the inflammatory process. Therefore, rectal suppositories, for example, Diclofenac, are most widely prescribed.

List of effective anti-inflammatory drugs

In the treatment of inflammation in the prostate gland, products sold in pharmacies without prescriptions are very popular. They are easier to buy, and therefore some men use them without a doctor’s prescription, which is wrong.

It is necessary that the drugs be prescribed by a urologist, who can determine the degree of their danger taking into account the patient’s health condition and the drugs of another group he is taking.

For prostatitis the following may be prescribed:

1. Diclofenac is a powerful non-selective anti-inflammatory drug that copes well with pain. If taken for a long time or incorrectly, it can cause a heart attack and liver problems.
2. Ibuprofen is a non-selective NSAID that relieves pain and lowers body temperature. With prolonged use, anemia may develop.
3. Aspirin. It is often used as an antipyretic, but also has an anti-inflammatory effect. In this case, the drug can cause internal bleeding.
4. Celebrex is a selective anti-inflammatory drug that does not affect the gastrointestinal tract.

These and other drugs, although indispensable in the treatment of prostatitis, can negatively affect the body, and therefore should be taken with caution, in strict accordance with the doctor’s instructions.

Do not self-medicate and follow the instructions for use, this will help maintain your health.

Conclusion

In the treatment of prostatitis of various etiologies and forms, non-steroidal anti-inflammatory drugs are important. Steroid drugs (corticosteroids) are not used for this urological disease. Taking any drug is associated with health risks; problems with the stomach, liver, intestines, and heart may begin, and therefore caution should be exercised.

For prostatitis, rectal suppositories or injections are often prescribed, but pills cannot be ruled out. In any case, you must strictly follow the doctor’s instructions, do not change the dosage or increase the course of treatment.

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Source: https://prostatits.ru/preparaty/protivovospalitelnye-pri-prostatite.html