What kind of cough would Lazolvan be the most effective remedy for?

To treat dry cough, therapists often prescribe a drug such as Lazolvan. This remedy, depending on the age category, can be prescribed in the form of ampoules, syrup and tablets. But not all dosage forms of this drug prescribed for adults are suitable for children. Taking this into account, before using the drug it is necessary to consult a specialist and also read the instructions for this drug in detail.

Cough treatment

Lazolvan is a mucolytic drug. The ambroxol contained in it helps to increase and dilute sputum in the lungs, as a result of which, with a dry cough, its viscosity becomes less and is more easily expectorated. As a result, the cough is cured much faster.

The sooner you start using Lazolvan, the faster the cough will go away. Syrups, tablets and ampoules of the drug are prescribed for various diseases that are accompanied by an increased content of mucus in the respiratory tract. All of them can manifest themselves in acute and chronic forms, for example:

1. Bronchitis (acute or chronic).
2. Inflammation of the lung tissue.
3. Bronchial asthma.
4. Bronchiectasis.

This remedy is also used for faster intrauterine maturation of the lungs, when there is a danger of premature birth.

If a respiratory syndrome is diagnosed in an infant, it is used for therapeutic and also prophylactic purposes.

Lazolvan begins to act approximately 20-25 minutes after the patient takes the tablet or syrup.

This drug is often used to treat bronchitis, as it provokes the rapid production and discharge of mucus from the pulmonary tract, as a result of which pathogenic microorganisms are eliminated from the body. Thanks to this, Lazolvan makes it possible to:

• normalize the composition of sputum;
• increase the volume of sputum during a dry cough, thereby enhancing the expectoration process;
• when taking the drug together with antibiotics, increase the effect of the stronger drug.

In the treatment of pneumonia, the effect of the drug is to restore the normal functioning of the bronchi, liquefy and remove viscous sputum from the body.

This remedy is prescribed for the treatment of advanced pneumonia, as it promotes the active production of pulmonary lubrication.

Lazolvan also enhances the effect of antibacterial agents, making it possible to use a smaller dose of the drug.

Application of Lazolvan

Lazolvan, produced in tablet form, is prescribed to adults and children over twelve years of age. During the first day, you need to take 1 tablet 3 times a day, after meals. All subsequent days, the dosage rate is reduced to 1/2 tablet 3 times a day.

If absolutely necessary, Lazolvan in tablet form can be given to a child over six years old. You need to take half a tablet no more than 3 times a day.

Lazolvan syrup is prescribed to children aged 6 years and older, 1/2 teaspoon 3 times a day. Adults and children over 12 years of age should take the drug 1 tbsp. l. 3 times a day for the first 3 days, after which the dose of the drug should be reduced to 1 teaspoon.

In case of severe form of the disease, the dose of the drug does not change throughout the entire course of treatment.

Lazolvan in ampoules is used as intramuscular intravenous injections and in the form of droppers. Adults are prescribed 1 ampoule of 15 ml three times a day. If the patient has a severe form of the disease, the dosage is increased to 30 ml. When prescribing the drug to children, the required amount is calculated to be 1.6 mg per kilogram.

How to make eggnog for cough

Children under 2 years of age are prescribed 1/2 ampoule twice a day. For children 2-5 years old, the daily dose of this drug should not exceed 7.5 mg. Children over 5 years old are prescribed 1 ampoule 3 times a day. For postpartum respiratory syndrome, Lazolvan is administered intravenously or intramuscularly at 10 mg per kilogram of the child’s weight.

Lazolvan in the treatment of children

For dry and wet cough in children, doctors often prescribe Lazolvan in the form of syrup. It has a pleasant taste, and children drink it with pleasure. The drug is considered safe and has a good effect in the treatment of the respiratory tract. It has no contraindications, so it can be used to treat children over six years of age.

The syrup dilutes sputum well, making it easier to remove from the body. A more severe cough after taking several servings of the drug indicates that the mucus accumulated inside is beginning to clear and the child will soon recover.

For dry cough, Lazolvan can be used for inhalation. The solution, which must be diluted in liquid, is used to treat small children. Injections are used if the child has a severe cough.

Use of the product during pregnancy

Pregnant women with dry and wet cough are allowed to take Lazolvan in the second and third trimester, but only under the supervision of a doctor. During the first trimester, the formation of fetal organs occurs, so the use of the drug is contraindicated during this period.

The drug can pass into breast milk, so it must be used with extreme caution during breastfeeding.

Considering that no adverse reactions have been identified for this drug, doctors recommend using Lazolvan in the form of syrup to treat cough in children.

Source: https://KashelSovet.ru/lechenie/siropy/pri-kakom-vide-kashlya-mozhno-primenyat-lazolvan-suhom-ili-vlazhnom.html

Can Lazolvan make your cough worse? — My-witch doctor

The active ingredient of the drug is ambroxol. The name is familiar to many patients suffering from tracheitis, bronchitis, and asthma.

Lazolvan is used quite reasonably for dry coughs, due to the fact that the active substance of the drug effectively increases the secretion of surfactant in the lungs, stimulates the movement of the cilia of the epithelium lining the respiratory tract (ciliary activity), and increases the discharge of mucus.

Knowing this, it is very simple to answer the natural question from patients about what cough Lazolvan should be used for. As zashlyal.ru notes, it relieves dry, irritating coughs and helps remove pathogenic microorganisms and their waste products from the respiratory system.

Description of the drug

Lazolvan is considered one of the most effective remedies, as it does not suppress the cough reflex and improves the penetration of antibacterial agents into the mucus of the respiratory system.

Thanks to ambroxol, the duration of antibiotic therapy is reduced, and relapses of a chronic disease become less frequent. Its use prevents mucus adhesion and chronicity of the process. This sets Lazolvan apart from other mucolytics.

It is allowed to be given to patients of all ages, starting from early childhood.

The basis (indications) for the prescription of Lazolvan is the identification of:

• chronic obstructive diseases of the bronchi and lungs;
• asthma, with difficulty in mucus discharge;
• diseases of the lungs and bronchi of a viral-bacterial nature, accompanied by an irritating, “scratching” cough;
• presence of bronchiectasis.

Lazolvan belongs to the group of mucolytes that have an expectorant effect due to the secretolytic, secretomotor effect of ambroxol.

Release form

The drug is available in the form of:

• tablets (standard action, extended-release, regular, effervescent);
• syrup for oral use;
• solution for inhalation or per os (by mouth);
• in ampoules for intramuscular/intravenous administration.

Patients, according to some data from zakashlyal.ru, prefer to use syrup or a solution for internal use to treat cough if the medicine is intended for children, tablets if adults plan to take it.

Syrup

The solution is transparent, sometimes has a slight brown tint. This drug is bottled in dark amber glass bottles with a dropper. Each milliliter of solution contains 7.5 mg of the active ingredient.

Pills

The tablets are flat in shape, yellowish or pure white in color, with alphanumeric engraving “67”, “C”. On one side, each tablet is separated by a line. The tablet contains 30 mg of active substance.

Adults can take the drug in any convenient form. The tablet form is not recommended for children and adolescents under 18 years of age.

Suction time

Any form of the drug, as noted by zakashlyal.ru, is absorbed quickly, reaching a maximum in plasma 1 to 2.5 hours after administration. The effect of the tablet begins to be felt half an hour after taking it. The effect of an intravenous injection is felt almost instantly.

Time of action

The duration of the effect is 6-12 hours.

Adults can take the drug in any convenient form. The tablet form is not recommended for children and adolescents under 18 years of age.

Rules for taking Lazolvan for adults

Side effects rarely accompany the use of the drug. They manifest themselves as dyspepsia, skin reaction (rash) or sore throat. There are cases of prescribing Lazolvan that require special attention from a doctor (for example, severe liver pathology or renal failure). But it is not prescribed if you have an individual intolerance to any component of the medication.

As zakashlyal.ru notes, you should take the medication only on the recommendation of a doctor. Firstly, Lazolvan can interact with some medications; for example, it is not taken together with antitussive drugs, since sputum discharge worsens. Secondly, an overdose of the drug is possible, although such cases are rare.

In case of an overdose, there are no specific symptoms, but the patient may feel nausea, vomiting, and diarrhea. To avoid this, you need to follow the dosages indicated in the instructions.

The drug is prescribed as follows:

1. The tablet form is prescribed 3 times a day, 1 tablet.
2. Lazolvan for an irritating cough with a high frequency of attacks can be prescribed 2 tablets 2 times a day.
3. The solution/syrup for oral administration is prescribed to children over 12 years of age and adults, 100 drops (equivalent to 4 ml).
4. 15-30 mg is administered intravenously/intramuscularly 2-3 times/day.
5. The inhalation form is prescribed 2-3 ml/day, dividing the dose into 1-2 inhalations.

Inhalations with Lazolvan

To make inhalation, prepare a mixture of Lazolvan with saline solution in equal parts to maximize the effect. You can use any inhalation device, except steam. You should not inhale deeply; a deep breath provokes a coughing attack. Inhalations are carried out with a warm solution; patients with bronchial asthma can do inhalations only after taking bronchodilators.

Taking Lazolvan during pregnancy

Ambroxol penetrates the placenta barrier and is excreted in mother's milk, so the decision to take the medicine by a pregnant woman is made by the doctor, taking into account the benefit/harm ratio. It is not recommended to use the drug during breastfeeding, or you should stop breastfeeding while taking it.

In the initial period of pregnancy, the instructions recommend refraining from taking the medication; starting from the second trimester, Lazolvan is approved for use.

In clinical studies, no effect on fetal development, delivery or on the child when exposed to mother's milk was identified, but the specified restrictions should be observed.

For the elderly

Elderly patients do not require dose adjustment.

Rules for taking the drug by children

According to studies, the pharmacokinetics of ambroxol depends little on the gender and age characteristics of the patient. Many experts, including zakashlyal.ru, believe that there is no need to dose the drug depending on the patient’s age.

There is a link about this in the official instructions. However, the same official instructions have a gradation of the dose of medicine for the patient, based on his age. For inhalation, injection, and oral forms, the dosage method is given in Table 1.

Table 1. Daily doses of Lazolvan depending on the patient’s age

Age, years	Solution/syrup (orally), ml (mg)/drops	Frequency of intake/day	Dose, injection, mg/day	Frequency of intake/day	Dose (inhalation), ml/day	Frequency of intake/day
Up to 2	1 (7,5)/25	2	15 (Vienna)	2	—	—
2-6	1 (7,5)/25	3	22.5 (Vienna)	3	—	—
6-12	2 (15)/50	2-3	30-35 (muscle)	2-3	—	—
over 12	4 (30)/100	3	15-30 (vein, muscle)	2-3	—	—
Up to 6 years	—	—	—	—	2	1-2
After 6 years	—	—	—	—	2-3	1-2

The amount of Lazolvan for injections in children is calculated based on body weight: for intramuscular injections - 1.2-1.6 mg per 1 kg 3 times/day, for intravenous administration - 1.2-1.6 mg per 1 kg/day. The dosage regimen for children under 2 years of age can be adjusted by a pediatrician.

Use of the drug for the treatment of young children

There is no special Lazovan children’s uniform. But parents consider syrup for children because the child is more willing to drink a sweetish product than a solution.

In the injectable form, the drug is more effective and begins to act faster, but this dosage form is intended for the treatment of severe diseases. For example, the drug is effective for the treatment of severe respiratory distress in newborns (distress syndrome, RDS).

It is even used to accelerate the prenatal maturation of the fetal lungs if there is a threat of premature birth.

Parents ask what kind of cough this remedy is prescribed for. The drug is recommended for the treatment of a sharp, sputum-free (dry) cough that injures the baby’s airways. Lazolvan is considered one of the relatively safe medications.

It is allowed to be prescribed to children from a very early age; it is given to babies from the first year of life. Some sources recommend using Lazolvan solution by inhalation to treat infants.

The official instructions do not prohibit such use, but it is better to consult a pediatrician.

Many pediatric doctors speak out against any inhalations for infants, not considering the method effective. There are no significant features of the use of Lazolvan in childhood. All forms of the medication are effective in treating cough in patients of any age.

for inhalation with Lazolvan for a child

Source: https://zakashlyal.ru/lechenie-kashlya/lekarstva/lazolvana-pri-suhom-kashle.html

What should I do if my cough gets worse after inhalation?

• One of the effective methods of treating wet or dry cough is inhalation, for which a nebulizer is often used.
• Practice shows the effectiveness of this method; as part of complex therapy, it helps to cure even the most severe respiratory diseases.
• In some cases, the cough only gets worse after inhalation with a nebulizer; many do not know what to do about it and whether it is necessary to continue treatment.

Main types of inhalations

The most commonly used types are:

• heat-steam - the patient breathes a medicinal solution over a container;
• heat-steam with the use of an inhaler - are based on the same principle, the steam enters exclusively into the respiratory tract, the medicinal solution is located at a certain distance from the mouth and nose.
• using a nebulizer - the liquid turns into a vapor state under the influence of pressure;
• dry inhalations - the baby inhales vapors of citrus fruits, crushed garlic, and onions.

Important: Heat-steam inhalations using an inhaler and nebulizer are in greatest demand.

Causes of increased cough

What factors could have caused the child’s cough to intensify after inhalation? Symptoms in adults and children after using inhalations may increase for the following reasons:

• incorrect choice of drug - most often occurs during self-medication; if you have a wet cough, you should not take medications for a dry and unproductive cough;
• individual intolerance to the component;
• incorrect dosage - can also provoke a deterioration in well-being;
• non-compliance with the sequence of taking medications.

Choice of treatment depending on the type of cough

If a child coughs, you should immediately consult a doctor, he will diagnose and prescribe treatment. For dry cough, therapy is aimed at eliminating inflammatory processes in the throat, reducing the viscosity of mucus and removing it from the respiratory system.

In this case, inhalations with Ambrobene, Berodual show effectiveness; the drugs are diluted with saline. solution in a certain ratio. It is very important to adhere to the prescribed treatment regimen and be sure to follow a certain number of procedures per day.

Why does my cough get worse after using a nebulizer? In this case, the effect is associated with the properties of the drug used. The last inhalation should be carried out no later than 18 hours, this will prevent the occurrence of new coughing attacks.

The direction of therapy changes somewhat with a productive cough; its action should be aimed at removing sputum. In this case, the use of inhalations with lazolvan, mucaltin, borjomi and other expectorants shows effectiveness.

Why did the cough intensify after inhalation? Cough during inhalation with a nebulizer intensifies due to the intensification of the process of mucus formation caused by taking these medications.

1. In such cases, it is recommended to reduce the concentration of the drug as much as possible, since taking it increases the negative effects.
2. Important: when treating respiratory diseases, complex treatment is often used; in such cases, a certain sequence must be followed.
4. Sequence of taking medications:

• medications with a bronchodilator effect by inhalation;
• sputum thinners (after 30 minutes);
• antiseptic medications (after 30 minutes), combined use with anti-inflammatory drugs is allowed.

Why be consistent? Violation of this sequence can lead to the appearance of a hysterical cough in children and adults.

What to do if your cough gets worse after inhalation

If the cough intensifies after inhalation, there is no need to rush to discontinue treatment, as this is the most effective method of therapy.

It is recommended to monitor the baby for some time; the duration, frequency and characteristics of the attacks play an important role.

If the situation gets out of control and the condition worsens, you should consult a doctor. After the examination, the doctor will prescribe another drug or reduce the dosage; in any case, it is better to avoid self-medication.

Conclusion

Inhalation is an effective way to treat diseases of the respiratory system, but sometimes the method leads to the opposite effect.

If the cough intensifies after inhalation with lazolvan and other drugs, it is recommended to monitor the condition for some time; quite often the symptoms disappear on their own.

It is very important to observe the dosage and sequence of taking medications during complex therapy; it is also necessary to adhere to the treatment regimen. If the condition worsens, it is recommended to consult a doctor again.

(1 5,00

Source: https://myznaharb.ru/mozhet-li-ot-lazolvana-usilitsya-kashel.html

What kind of cough is treated with inhalations with Lazolvan?

Inhalations are used for colds, as they help eliminate cough and runny nose. What kind of cough is treated with inhalations using Lazolvan? This drug belongs to the group of mucolytic drugs that dilute sputum, so it is prescribed for dry cough. Let's look at how to properly make a solution for inhalation with lazolvan and saline.

Action of lazolvan

The active formula of the drug includes 7.5 mg of ambroxol, which increases the volume of sputum in the bronchi by stimulating the walls of the mucous membranes. The cilia of the epithelial layer of the bronchi begin to move and push clots of mucus into the throat. Along with an increase in sputum production, the drug helps to liquefy it, which facilitates the exit of exudate from the body.

Note! Lazolvan is prescribed for inhalation for dry cough, characterized by the production of viscous sputum.

Lazolvan for inhalation is used in nebulizers, with the help of which the smallest particles (aerosols) of the medicinal substance penetrate deep into the bronchi, even into poorly ventilated compartments.

Other treatment methods cannot have a similar effect, so inhalation with Lazolvan is the only and completely safe method of cleansing the bronchial tree from accumulated secretions. Lazolvan is a safe means of influencing the bronchial and pulmonary systems; it is used to stimulate the formation of lung tissue in the fetus during artificial birth. The drug is also used to prevent respiratory syndrome in newborns.

Indications

For what diseases is lazolvan prescribed? Pulmonologists write a prescription for the following ailments:

• bronchitis;
• bronchial asthma;
• pneumonia;
• bronchiectasis;
• damage to lung tissue.

For example, bronchiectasis is characterized by the accumulation of exudate in the dilations of the bronchial tissues, and only lazolvan is able to remove the accumulation of secretions from there.

If a child has a severe runny nose, take Lazolvan drops. They quickly relieve nasal swelling and do not dry out the mucous membrane. The drops help cleanse the nasal sinuses when exudate accumulates and remove mucus from hard-to-reach places in the nasal cavity. The use of drops must be approved by a doctor.

Contraindications

Inhalations with Lazolvan should not be carried out during any cough if the body temperature has risen above 38 degrees. This is a general prohibition when conducting inhalation sessions. Contraindications also apply to:

• nosebleeds;
• respiratory disorders;
• heart ailments and pathologies.

When treating obstructive diseases, a preliminary procedure is necessary using drugs that dilate the bronchial lumens - Berodual and others.

Rules for inhalation

How to take Lazolvan for a cough, and can a child inhale it? The drug is completely ready for use; there is no need to dilute it. However, for inhalation with a nebulizer, lazolvan is diluted with saline to increase the volume to 4 ml. Saline solution and Lazolvan are poured into the container for medicines in equal volumes.

In order not to provoke irritation of the lung tissue in the child, the medicinal solution is heated to body temperature - no higher than 37 degrees.

The nebulizer breaks down molecules of water and medicinal substances into aerosols, which should be breathed during the procedure.

The dosage of the drug for inhalation is as follows:

• for children from six years of age and adults: 2-3 ml of Lazolvan per procedure;
• for children under six years of age: 2 ml of the drug per procedure.

Number of sessions per day: adults no more than three inhalations, children - two.

When using a nebulizer inhaler, the following conditions must be observed:

• the procedure cannot be carried out immediately after eating - only after 1.5 hours;
• a treatment session cannot be carried out if the child is overtired or very excited;
• During the session you cannot talk or be distracted from the procedure;
• you cannot take a deep breath - this will provoke a coughing attack;
• after the session you need to lie quietly on the bed and relax;
• You cannot talk loudly, eat, go outside or engage in physical activity immediately after the end of the session - only after 1.5-2 hours.

Note! Carrying out an inhalation session before bedtime can provoke an active outflow of sputum, which will not allow you to fall asleep.

How long should you breathe aerosols? Three minutes is enough for children; adults can inhale for up to ten minutes.

Side effects

The drug lazolvan is a safe mucolytic agent, however, the patient’s body may react to its action in different ways. This is especially true for exceeding the dosage or violating the rules for conducting inhalation sessions. In addition, some patients cannot tolerate the inhalation procedure itself with any drug.

Possible side effects:

• nausea, stomach pain;
• dizziness, headache;
• disruption of the gastrointestinal tract;
• allergic manifestations.

If such symptoms appear, you must notify your doctor. A temporary increase in temperature after an inhalation session is not considered pathological - it is the activation of the immune system to protect the body's systems from infection. The elevated temperature can be brought down half an hour after the session.

It is strictly forbidden to take cough suppressants simultaneously with Lazolvan! The drug helps to increase sputum production, and suppressing the cough reflex with another drug will lead to greater complications.

Patients with bronchial asthma may develop spasm of the respiratory tract after inhalation with lazolvan. Therefore, before using the drug, you need to use bronchodilators that help expand the lumen of the bronchial tree.

If intolerance to the components of the drug is detected, the doctor will select an analogue of Lazolvan.

Bottom line

We found out for which cough inhalations with Lazolvan are prescribed. This drug is completely safe and can be used for inhalation and treatment of infants.

Lazolvan can also be used by pregnant and lactating women, because it does not have a harmful effect on the fetus. However, you cannot prescribe yourself treatment with the drug - there are many contraindications for use.

Only a doctor can prescribe treatment for bronchopulmonary diseases.

(1

Source: https://ingalyatsii.ru/bolezni/pri-kakom-kashle-naznachayut-lazolvan.html

What cough does Lazolvan help with?

"Lazolvan" is a drug that is intended for the treatment of inflammatory processes of the upper and lower respiratory tract. It is used in the treatment of diseases accompanied by a wet cough. The active substance of the drug is ambroxol hydrochloride, which has a secretory, expectorant and secretolytic effect. "Lazolvan" is highly effective in treating respiratory tract ailments and is used as an antitussive. Indications for use of the drug are: - bronchiectasis, bronchial asthma; - acute pneumonia; - chronic rhinitis, sinusitis; - acute tracheobronchitis; acute bronchitis; obstructive bronchitis; Chronical bronchitis;

- laryngitis, laryngotracheitis, nasopharyngitis;

- cystic fibrosis of the lungs.

The effect of “Lazolvan” when taken in the form of syrup or in tablet form occurs after 30 minutes, when using injections and inhalations - 3-5 minutes. The effect of the medicine lasts approximately 10 hours. The drug forms dobramantranilic acid in the liver and is excreted from the body by the kidneys.

“Lazolvan” is available in the form of tablets, solution for inhalation, lozenges, and syrup for children. Manufactured by Boehringer Ingenheim.

Doctors prescribe the medicine in tablet form to adults at a dosage of 30 mg three times a day. If it is necessary to enhance the therapeutic effect, you can use 60 mg, but twice a day. The tablets are taken after meals with water.

The drug is in the form of a syrup containing 30 mg of ambroxol in 5 ml; children over 12 years of age and adults should drink 5 ml three times a day; children from 6 to 12 years old - 2.5 ml two to three times a day.

“Lazolvan”, produced in syrup 15 mg/5 ml, is recommended for children under 2 years old, 2.5 ml twice a day; Children from 2 to 6 years old should drink 5 ml two to three times a day. It is advisable to take the drug with meals.

An expectorant for inhalation is prescribed in the following regimen: adults - 4 ml, children over 6 years old - 2 ml, from 0 to 6 years old - 1 ml. The drug should be mixed with saline in a 1:1 ratio in order to achieve optimal air humidification in the mask. It is recommended to warm the solution to room temperature before use.

If the solution must be taken orally, it should be diluted in milk, fruit juice, tea or water and taken with meals.

Lazolvan, when taken for a long time, can cause side effects such as gastralgia, vomiting, heartburn, and nausea.

Also side effects from the drug are allergic reactions: urticaria, skin rash, contact dermatitis, angioedema.

Medical articles on the Site are provided for reference purposes only and are not considered sufficient advice, diagnosis, or physician-prescribed treatment. The content of the Site is not a substitute for professional medical advice, examination, diagnosis or treatment. The information on the Site is not intended for independent diagnosis, prescription of medications or other treatment. Under any circumstances, the Administration or the authors of these materials are not responsible for any losses incurred by Users as a result of the use of such materials.

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Source: https://www.kakprosto.ru/kak-880774-ot-kakogo-kashlya-pomogaet-lazolvan

Lazolvan is suitable for dry cough

Lazolvan for dry cough is used to treat both adults and young patients. This drug enjoys the well-deserved trust of doctors. Its effectiveness has long been proven, and thanks to various forms of release, Lazolvan for cough can be prescribed to patients of any age.

Cough is one of the protective reactions of the human body. It helps cleanse the lungs and bronchi from phlegm accumulated in them. With a high degree of viscosity, its removal is difficult; special medications are needed to thin the sputum, one of which is Lazolvan.

Features of the composition and mechanism of action

Many patients ask questions about what kind of cough can be treated with Lazolvan, and in what form it is better to use the drug.

A dry cough requires immediate medical intervention, as it not only causes discomfort, but also causes pain.

It is important to alleviate the patient’s condition by accelerating the removal of mucus from the bronchi, making it more liquid. Lazolvan helps to achieve the desired effect for coughs that occur in cases where the inflammatory process develops in the bronchi.

The main active ingredient of the drug is Ambroxol, which:

• helps reduce the viscosity of mucus accumulated in the bronchi;
• improves the functionality of epithelial cells;
• activates expectorant reflux.

Due to the significant secretomotor effect of Lazolvan, during a dry cough, the viscosity of sputum decreases, it thins out and is much easier to remove through the respiratory tract.

Answering the question about which cough to take the drug for, it should be said that it is prescribed more often for dry cough.

The mucolytic and pronounced expectorant effect of all components included in the drug is used in the treatment of diseases accompanied by a pronounced cough reflex and clearly difficult removal of sputum.

• The use of Lazolvan for dry cough makes it possible to activate the production of mucous and other components of sputum.
• Under the influence of Ambroxol, which is part of the drug, the mobility of ciliated cilia increases, and mucus is easily removed from the bronchi.
• We recommend reading! Follow the link:
• How to get rid of cough in children
• When carrying out therapeutic measures aimed at eliminating wet cough, a special dosage is established for children and the use of Lazolvan inhalation solution is provided.

When a child has a wet cough, significant thinning of the sputum is not required; it is important to ensure its effective removal.

The dosage and regimen are determined by the attending physician depending on the child’s age, weight and general condition.

A child's dry cough differs significantly from a similar appearance in adults, and if treating an adult requires taking a tablet or lozenges, then a syrup and inhalation solution have been created for coughing children.

When working with children, it is important to take into account the characteristics of the child’s body. Inhalations with Lazolvan are carried out from one to three times a day. It depends on the severity of the baby's condition.

To prepare the composition used during each procedure, you will need:

• 25 drops of Lazolvan (1 ml), containing 7.5 mg of active ingredient;
• saline solution (sodium chloride).

The proportion for preparing the solution is 1:1. The maximum effect can be achieved by carrying out the procedure using a nebulizer. This device can be used at home. Its main advantage is that with its help the medicinal composition penetrates quite deeply into the bronchi and lungs, preventing the alveoli from sticking together.

A quick positive result can be achieved by using Lazolvan for a barking cough characteristic of laryngotracheitis (false croup). In this case, in the acute stage of the disease, inhalations are carried out 3-4 times a day, achieving noticeable relief in breathing. For barking cough, children can be given Lazolvan syrup.

The frequency of administration and dosage depend on the age of the young patient.

Inhalations for dry cough can be carried out using:

1. Children aged 2 to 6 years – 15 mg solution + 25 drops of sodium chloride three times a day.
2. From 6 to 12 years – 22.5 mg of the medicinal composition + 50 drops of saline 2 times a day no later than 30 minutes before eating or drinking.
3. Older children are allowed to drink a solution of 2 ml in the morning, at lunch and after dinner.

The use of syrup for the treatment of dry cough in a child is carried out strictly as prescribed by the doctor:

• patients under 2 years of age drink 7.5 mg syrup 2 times a day. You can determine the exact dose using a measuring spoon;
• from 2 to 6 years – 22.5 mg divided into 3 doses;
• from 6 to 12 years – 45 mg in three doses (15 mg each);
• from 12 and older - 90 mg is divided into three doses, but it is not recommended to exceed this dosage.

It is important to follow the indicated dosage to avoid side effects. If you give the daily dose in one dose, you may experience diarrhea, heartburn, and skin rashes.

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• Bronholitin syrup - perfect for the treatment of dry cough in children (Average cost in a pharmacy is 100 rubles) Paxeladin syrup - is an analogue of the above product, but in a different price category (Average cost in a pharmacy is 250 rubles) We also recommend that you read the article of your choice cough syrup.

Pills:

Stoptussin - excellent and inexpensive cough tablets for children (Average price in a pharmacy is 110 rubles) Sinekod - excellent tablets for dry cough for children (Average price in pharmacies is 200 rubles) Glauvent - also very good cough tablets (Average price in pharmacies 250 rub)

We also recommend that you read the article on choosing cough tablets for children.

Sprays:

Inhalipt is an excellent and inexpensive cough spray for children (Average price in a pharmacy is 60 rubles) Faringosept is also a very good cough spray (Average price in a pharmacy is 110 rubles)

Tantum Verde is an excellent drug in the form of a spray, in a high price category (Average price in pharmacies is 300 rubles)

Stoptussin syrup is perfect for the treatment of dry cough in adolescents and adults (Average cost in a pharmacy is 150 rubles) Sinekod drops are also an excellent remedy, but in a different price category (Average cost in a pharmacy is 350 rubles)

We also recommend that you read the article on choosing cough syrup.

Pills:

Mukaltin - excellent and inexpensive cough tablets (Average price in a pharmacy is 50 rubles) Sinekod - this excellent drug is also sold in tablet form (Average price in pharmacies is 150 rubles) Solutan - also very good tablets for cough treatment (Average price in pharmacies 200 rub)

We also recommend that you read the article on choosing cough tablets.

Sprays:

Inhalipt is an excellent and inexpensive cough spray (Average price in a pharmacy is 60 rubles) Hexoral is also a very good cough spray (Average price in a pharmacy is 170 rubles)

Tantum Verde is an excellent drug in the form of a spray, in a high price category (Average price in pharmacies is 300 rubles)

1. With answer
2. With a viewing mark

1. Task 1 of 6

   Please indicate your age (your child's age)

   • From 6 to 12 years
   • From 12 to 18 years old
   • Over 18

2. Task 2 of 6

   In what price range can you afford a cough medicine?

   • Up to 100 rubles
   • From 100 to 200 rubles
   • Over 200 rubles

3. Task 3 of 6

   In what form do you prefer to take your cough medicine?

4. Task 4 of 6

   What type of cough is bothering you?

5. Task 5 of 6

   Rate the severity of the cough on a five-point scale

6. Task 6 of 6

   Whose product would you prefer?

   • Domestic
   • Foreign

Coughing is a protective reaction of the body. If this symptom lasts for several days, it can be assumed that the person’s respiratory organs have undergone an infectious attack.

In order to bring the moment of recovery closer, it is necessary to achieve the transformation of a non-productive cough into a wet one. Lazolvan works well for patients of all ages for dry coughs.

The medicine is available in several forms, making it excellent for both adults and children.

Source: http://med-zoj.ru/kashel/pri-suhom-kashle-podhodit-lazolvan.html

Lazolvan in the treatment of patients with productive cough

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Published in the journal: Directory of a polyclinic doctor | No. 2 | 2011

I.L. Klyachkina Department of Pulmonology RMAPO, Moscow

A productive cough is one of the most common symptoms of respiratory diseases. Coughing removes excess bronchial mucus (BM) from the airways. It should be noted that the definition of “productive cough” means the development of hyperproduction of BS, in which there is an increase in expectorated sputum.

For example, the main clinical symptoms of chronic obstructive pulmonary disease (COPD) are cough with hard-to-clear sputum and shortness of breath, with productive cough appearing much earlier than shortness of breath. The effectiveness of cough and its intensity depend on the rheological properties of BS - viscosity, elasticity and adhesiveness.

Ineffective cough (lack of expectoration of sputum) is often a consequence of significantly increased viscosity of BS.

The secretion-forming elements of the bronchial mucosa begin to produce large amounts of sticky, viscous mucus. An increase in the content of neutral mucoproteins leads to an increase in the gel fraction in the bronchial secretion and, accordingly, an increase in its viscoelastic properties and adhesiveness (deterioration of the rheological properties of BS).

Deterioration of the rheology of bronchial mucus (BM), the development of oxidative stress, and the direct effect of aeropollutants on the ciliated cells of the mucous membrane (metaplasia of epithelial cells) disrupt the effectiveness of mucociliary clearance, blocking its cleansing function. Increasing the viscosity of mucus and slowing the speed of its movement contribute to fixation, deeper penetration and colonization of respiratory microorganisms into the thickness of the mucous membrane, further worsening mucociliary clearance.

Hyperproduction of mucus in combination with mucociliary dysfunction as the disease progresses can disrupt the drainage function of the bronchi and affect bronchial patency.

With an increase in the viscosity of bronchial secretions, its speed of movement slows down (by 10-55%) or stops altogether, and at night the viscosity of bronchial secretions in patients with COPD is significantly higher than during the day.

That is why patients so often complain of a severe cough in the morning upon waking up.

Therapy

Thus, in the treatment of productive cough (including in COPD), drugs are needed that have mucolytic, mucokinetic and mucoregulatory activity, facilitating the expectoration of pathologically altered BS, preventing mucostasis and improving mucociliary clearance.

With the facilitation of the separation of BS in the bronchi, one of the factors causing bronchial obstruction is eliminated, and the likelihood of microbial colonization/respiratory tract infection (RTI) is also reduced.

In addition, due to the development of oxidative stress, the need for the use of antioxidants, which have an anti-inflammatory effect on the mucous membrane and, indirectly, restore mucociliary clearance, becomes obvious.

Criteria for the effectiveness of mucolytic therapy

1. Well-being (improved quality of life). 2. Symptoms (reduction or disappearance of shortness of breath at rest or during exertion, reduction and relief of cough, change in the nature of sputum).

3. Some indicators of external respiration function (characterizing bronchial patency), such as forced expiratory volume in 1 second, vital capacity function, Tiffno index, maximum volumetric velocities, and concentration of gases in the blood.

All drugs that affect the rheology of BS and mucociliary clearance can be divided into 2 groups - direct and indirect action (see table). The peculiarities of the mechanisms of action of the most frequently and successfully used drugs - ambroxol, acetylcysteine ​​and carbocysteine ​​- require the attention of doctors and the correct selection of the drug in each specific case.

Among the existing variety of drugs that alleviate expectoration, a group of synthetic mucolytic drugs should be noted. Ambroxol* occupies a special place in this group.

Ambroxol is an active metabolite of bromhexine, a synthetic derivative of the alkaloid vasicine. Ambroxol was first synthesized in 1978 by Boehringer Ingelheim and is known in Russia under the name Lazolvan®.

Ambroxol is superior to bromhexine in terms of the speed of onset of effect and clinical effectiveness, since it is a direct metabolite.

Lazolvan® has the following important properties:

— Mucolytic effect — Lazolvan® potentiates the activity of enzymes that contribute to the dilution of bronchial secretions by breaking down acidic mucopolysaccharides of sputum. - Mucokinetic effect - activates the movement of the cilia of the ciliated epithelium of the bronchi, restoring mucociliary clearance.

— Mucoregulatory effect — normalizes the functions of the altered serous and mucosal glands of the bronchial mucosa and activates the production of the serous component of BS. This effect of Lazolvan® is especially important for patients with chronic lung diseases who experience hypertrophy of the bronchial glands with the formation of cysts and a decrease in the number of serous cells.

A very important property of Lazolvan® is its ability to increase the amount of surfactant, both enhancing its synthesis in Clara cells and type II alveolar pneumocytes, and preventing its breakdown.

It has bactericidal activity against gram-positive microorganisms and stimulates the function of macrophages, which contributes to the elimination of bacteria.

Surfactant begins to be produced at the 20-24th week of embryonic development of the fetus, the surfactant system fully matures by the 35-36th week of intrauterine development and its intensive release occurs at the time of birth.

Disruption of surfactant synthesis and its accelerated destruction can occur under various pathological conditions and therapeutic manipulations: hypoxia, inflammatory processes in the lungs, small bronchi and bronchioles, malignant neoplasms, exposure to tobacco smoke, infection of the respiratory tract (especially gram-negative flora, mycoplasma), diabetes mellitus, long-term (4-6 hours) fluorotane anesthesia, artificial ventilation, the need for long-term oxygen inhalations in high concentrations, the use of inhalation therapy using metered-dose aerosol inhalers, etc.

Based on these provisions, it becomes clear that the use of Lazolvan® is useful in the treatment of patients with COPD, bronchial asthma, who are constantly receiving inhalation therapy, including long-term oxygen therapy.

In patients in intensive care and resuscitation departments, including neurological ones, intensive and uniform sputum production is observed during the day against the background of inhalation or instillation of ambroxol in the DP.

A number of clinical studies have shown that only two drugs have proven the ability to accelerate the maturation of fetal lung tissue when there is a threat of premature birth. These are glucocorticosteroids and Lazolvan®.

Lazolvan® reduces the incidence of neonatal distress syndrome by 2-3 times, but is incomparably safer than glucocorticosteroids.

The ability to synthesize surfactant is also potentially useful in the treatment of patients with acute exudative otitis media. It has been noted that the phospholipids lining the surface of the mucous membrane of the Eustachian tube are similar in structure to pulmonary surfactant.

The effectiveness of Lazolvan® in the treatment of this disease was proven in a multicenter, double-blind, placebo-controlled study involving 435 adults and children (Mira et al., 1997).

The effectiveness of therapy is due not only to the effect of Lazolvan® on surfactant synthesis, but also to its mucolytic effect.

An important place in the treatment of respiratory infections (pneumonia, exacerbation of COPD, etc.) belongs to antibacterial therapy. However, the prescription of etiotropic therapy does not always have the necessary immediate effect. Antibiotics significantly increase the viscosity of BS due to the lysis of microbial bodies, leukocytes and DNA release. The excessive viscosity of BS makes it difficult for antibiotics to penetrate into it.

Research

Several double-blind, placebo-controlled studies have shown that Lazolvan® leads to an increase in the rate of passive diffusion of antibiotics from the blood plasma into the lung tissue without changing the concentrations of antibiotics in the blood plasma.

Combination therapy of antibiotics and Lazolvan® in patients with various infectious pathologies of the respiratory system led to a statistically significant increase in the concentration of b-lactam antibiotics and macrolides in the bronchial secretions, a decrease in the severity of cough and an improvement in sputum discharge compared to patients receiving only antibiotics.

In children with acute pneumonia, combination therapy of Lazolvan® with b-lactams or macrolides led to earlier normalization of the X-ray picture (79% compared to 53%, p

Source: https://medi.ru/info/9090/