Progestogel gel: an effective remedy for the treatment of mastopathy

Mastopathy ointment is a means for external use that does not penetrate the blood. This treatment is more effective when used as a combination therapy. Ointments can relieve painful symptoms, eliminate swelling, relieve inflammation and even reduce the size of tumors.

The principle of action of ointments for mastopathy

The main feature of external use is their local effect, they do not enter the blood circulation. To treat the disease at an early stage, it is enough to use ointments, creams and gels and adjust the vitamin and mineral balance. For more advanced forms of mastopathy, external remedies are effective only in the context of complex treatment.

The main principle of action of ointments, creams and gels with synthetic hormones is the restoration of normal hormonal levels in the gland, in particular progesterone and estrogen. When applied, the product penetrates the muscle and connective tissue. Herbal preparations have a symptomatic effect: they relieve swelling, eliminate pain, and stop the inflammatory process.

General rules of treatment

The average duration of therapy with hormonal ointments is from 4 to 8 months. In this case, it is necessary to apply the drug 1-2 times daily.

Basic rules of treatment:

1. When applying ointments, creams, gels, the nipple area is not affected.
2. Before using the product, be sure to clean the affected area.
3. The main direction of movement during manipulation is circular with light strokes.
4. Intense exposure is excluded; it can lead to rupture of seals and the onset of an inflammatory process.
5. When applying, avoid areas with external damage (abrasions, rashes, etc.).

Treatment with external herbal remedies lasts 2 times longer. At the same time, replacing hormonal drugs with herbal ones is not allowed. The latter only eliminate the symptoms of pathology, but do not restore hormonal balance and do not contribute to the resorption of tumors.

The best ointments, creams and gels

Ointments for mastopathy can be hormonal, non-hormonal, or based on herbal ingredients. Depending on the severity of the pathology, the woman’s age, and the presence of chronic diseases, an individual selection of an effective medication is carried out.  

Progestogel

The dosage form of Progestogel is a gel. This progesterone-based product blocks the production of estrogen.

At the same time, Progestogel increases the level of progesterone locally, at the site of exposure, without affecting the general hormonal background of the woman. The drug relieves swelling and relieves pain. Progestogel contains the enzyme estradiol.

It prevents the appearance of stagnation in the gland during the oxidation process and has a beneficial effect on the condition of blood vessels.

The drug is intended for daily use. To maintain the required dosage, the product comes with an applicator. For a single use, 2.5 g of gel is required. It is rubbed into the skin after hygiene procedures.

Recommended for daily use or from the 15th day of the cycle for 3 cycles. Gel for mastopathy is contraindicated after the 12th week of pregnancy, with nodular mastopathy, or the presence of an oncological process.

Doctor

Recommended for diffuse forms of mastopathy with a predominance of fibroids. The product is available in the form of a cream.

The main component is red palm oil. It stimulates lymph flow, improves blood circulation and activates metabolism. The medicine is a plant-based drug and contains extracts from plants:

• arnica;
• freshwater;
• mustard seeds;
• red pepper;
• aloe extract, etc.

Contains beeswax and D-panthenol, which promote active tissue healing. The cream relieves pain and stops secretion from the glands, eliminates swelling.

It should be used 2-3 times a day, the optimal time is after waking up and before bed. It is better to start treatment from the 15th day of the cycle, when painful symptoms intensify. The course of treatment is at least 2 weeks. It is not recommended to use the product for the mammary glands if the skin is damaged.

Apilak

Apilak is a non-hormonal drug. Available in ointment form. It has an analgesic effect, improves cellular metabolism and activates the tissue healing process. The main active ingredient is royal jelly of bees. The ointment must be applied at least 2 times a day. The duration of treatment is determined by the attending physician. It is not recommended to use the drug if you are allergic to bee products.

MastofitEvalar

Herbal preparation. The cream is not a drug and is prescribed to enhance the effect of medications used for mastopathy in women. Mastofit has the following properties:

• reduces swelling of the mammary glands;
• resolves seals;
• slows down the aging process of cells;
• has anti-cancer properties;
• activates metabolism.

The main components of the cream for breast mastopathy are:

1. Indole-3-carbinol prevents cancer (naturally occurring in broccoli).
2. Phytoestrogens (natural plant compounds) eliminate hormonal imbalances and improve the antioxidant properties of cells.
3. Fucus extract (a plant that is a source of organic iodine).

Excipients promote deep and rapid penetration of the active components into the gland tissue, improve the appearance and condition of the skin. It is not recommended to use the cream during pregnancy, lactation, or with high estrogen levels. The product must be used twice a day. The duration of therapy is 60 days.

Celandine ointment

The composition of celandine includes alkaloid substances (large amounts of chelidonine, homochelidonine, sanguianarine, chelerythrine), flavonoids, vitamins A and C, tannins, etc.

Sanguianarine and chelidonine act as an analgesic and have antiseptic properties. In addition, chelerythrine has an antitumor effect. Flavonoids strengthen the walls of blood vessels, which promotes microcirculation in the chest.

Sanguinarine relieves inflammation. Tannins rid the gland tissue of toxins.

To prepare an ointment from the plant, you will need fresh leaves of celandine during the flowering period. It is crushed in a convenient way until a homogeneous consistency is formed. Squeeze out the juice. Ghee or fat is added to the celandine in a ratio of 1 to 1. Mix everything.

The resulting ointment is used to lubricate the breasts, with the exception of the nipple area, once a day. The course of treatment is at least 1 month. The drug is used only after consulting a doctor. When preparing, you must strictly follow the recipe, because the plant contains toxic substances.

Vishnevsky ointment

The direct purpose of the medication is to remove pus through the skin. Therefore, the use of the drug in its pure form for mastopathy can lead to the transition of the diffuse form of the disease to a nodular one. Many doctors do not recommend the use of ointment even as a component of traditional medicine.

Along with this, many women note the effectiveness of the recipe with Vishnevsky ointment and fir oil. To prepare it, the oil is mixed with ointment in a ratio of 7 to 3. Baby cream is added to the mixture in the ratio of 1 part of the mixture to 3 parts of the cream.

The resulting product is applied to a piece of fabric and applied to the affected areas of the chest. The top is covered with polyethylene. The compress is changed three times a day. The use of this product during pregnancy and breastfeeding is not recommended.

Traumeel

The product is available in the form of a gel and ointment. Traumeel is a homeopathic remedy. Most of the ingredients included in its base are of plant nature:

• calendula;
• echinacea;
• arnica;
• belladonna;
• chamomile, etc.

Many of these components relieve inflammation and promote tissue healing. Witch hazel effectively eliminates menstrual irregularities. The mineral components of the drug have immunomodulatory properties.

Traumeel is used both in the early stages of the disease and in the later stages, up to the precancerous state. The drug effectively relieves chest pain, swelling and reduces inflammation. In the fibrocystic form, the use of ointment (gel) promotes the resorption of small cysts.

Traumeel is used daily, 2 times - in the morning and at night. For severe pain, the frequency of daily applications is increased to 4–5. Therapy lasts from 14 to 21 days.

Troxevasin ointment

The ointment eliminates foci of inflammation. It is used for the breast due to its anti-edematous properties, it stimulates blood circulation, strengthens capillaries and blood vessels. It also copes with painful sensations and eliminates inflammation.

Apply the ointment twice a day. The duration of therapy is determined by the attending physician. The drug is contraindicated during pregnancy.

Cream wax Zdorov

The drug is of plant nature. Recommended for mastopathy due to the healing properties of the components:

1. Beeswax stimulates tissue repair.
2. Cedar resin promotes blood circulation in damaged areas, eliminates swelling and resolves formations.
3. Bee venom improves blood circulation and has antitumor properties.
4. Propolis extract has antiseptic and antioxidant properties.
5. Horse chestnut extract is effective against edema.

In addition, the cream contains vitamins PP, B, folic acid, olive oil, dead bee extract, etc. The drug should be used twice a day, the second time is better at night. The average course of treatment is 3–4 weeks. Cream wax has virtually no contraindications.

Indovazin

Available in the form of gel and ointment. Indovazin relieves inflammation. It is taken to relieve swelling and eliminate engorgement of the glands, for pain relief. It is recommended to use the drug for no more than 10 days. The use of Indovazin is contraindicated in the presence of damage to the skin of the chest to avoid burns.

Propolis ointment

Propolis-based ointment relieves inflammation and has a strengthening effect. The basis of the home remedy is animal fat with Vaseline or fatty cream. It is important to maintain the percentage of propolis and base.

For 3 parts of propolis there should be 1 part of the base in order to obtain a 30% product. To mix the ingredients, they need to be heated in a water bath until a more liquid consistency is obtained.

After mixing, place the ointment in the refrigerator.

Apply the product daily for half an hour. Therapy lasts 7–14 days.

Zorka

This cream is used in veterinary medicine to treat mastitis in cows. It eliminates puffiness, tones the skin, and stimulates metabolic processes.

The product is used in traditional medicine recipes. Its effect on the human body has not been established, and there is also no information about contraindications to the use of the cream.

According to the folk recipe for mastopathy, the cream is applied daily to painful areas of the chest. Continue use until symptoms of the disease disappear.

Mamma gel

The drug has a plant base and is classified as a cosmetic product. It contains essential oils and plant extracts (thuja, geranium, tea tree).

The main effect of the drug is to eliminate inflammation, improve blood circulation, relieve pain and disinfect. Due to the high content of essential oils, it is recommended to test for allergies to the gel.

To do this, apply a small amount of the product to a small area of ​​skin, after 5-7 minutes assess the condition of the skin. The product must be used 2 times a day. The duration of treatment is determined individually in each case.

As a rule, the course of treatment lasts at least 1 month.

Source: https://mammolog.guru/zabolevaniya-grudi/mastopatiya/maz.html

Progestogel gel: instructions for use for mastopathy, price, reviews and cheap analogues

Progestogel is included in the clinical and pharmacological group of hormonal drugs. This determines its fairly wide list of contraindications. To eliminate the possibility of unwanted side effects, a woman should use this local remedy only as prescribed by a doctor.

Composition and release form

The Belgian manufacturer produces Progestogel in the form of a jelly-like transparent gel without any characteristic odor. It is packaged in 80.0 g units in sealed aluminum tubes. Each is enclosed in a cardboard box along with instructions for use. The active composition of the 1% gel is represented by progesterone, a sex hormone that affects the menstrual cycle.

Applicator, tube, packaging To form the gel base of the drug, the manufacturer used the following components:

• carbomer;
• triethanolamine;
• polyoxyethylene;
• ethyl alcohol;
• purified water;
• castor oil;
• octyl-2-dodecanol.

Auxiliary ingredients ensure rapid absorption (penetration) of progesterone into breast tissue.

They promote optimal distribution of the steroid, and also enhance and prolong its effects. Progesterone is transformed directly in soft tissues.

Only secondary metabolism occurs in liver cells, and then the converted hormonal agent is excreted from the body.

Pharmacological properties

The therapeutic activity of Progestogel is due to the presence of a high concentration of progesterone in its composition. After penetration into tissues, it blocks estrogen-sensitive receptors. This leads to accelerated resorption of edema, which compresses the milk ducts and nerve endings. At the same time, prolactin receptors are blocked, which slows down the production of breast milk.

Formula of progesterone - the active substance Progestogel is characterized by other pharmacological effects that have a positive effect on a woman’s well-being:

• reduction of local estrogen levels due to increased production of enzymes that oxidize estradiol;
• increased cellular filtration, prevention of fluid retention;
• decreased permeability of small blood vessels.

After the accumulated fluid stops compressing the sensitive nerve endings, the pain subsides. If the course of mastopathy is accompanied by inflammation, the pathological process first slows down and then stops. Improving blood circulation in the mammary gland causes accelerated recovery of damaged tissue.

Indications for use

Progestogel ointment is intended for the treatment of mastopathy. This is the name of the pathology, which is characterized by fibrocystic changes in the tissues of the mammary gland.

Dense, fine-grained compactions form in them. But the drug is used only for diffuse fibrocystic mastopathy.

Its distinctive feature is the formation of both fibrous foci and fluid-filled cavities (cysts).

Simulated breast image

Another indication for the use of a hormonal drug is mastodynia. It is included in treatment regimens when women complain of the following symptoms:

• constant discomfort in the mammary gland;
• pain that increases with pressure;
• thickening of the mammary gland due to excessive accumulation of fluid in it.

Progestogel can be used as monotherapy for mastopathy. But mastodynia sometimes becomes a clinical manifestation of more serious diseases, such as breast cancer.

In such cases, the hormonal drug is used only in combination with other drugs. The gel has also proven itself in the treatment of fibroadenoma.

  This is a benign breast tumor of glandular origin, one of the forms of nodular mastopathy.

Contraindications

The gel is not prescribed to patients with individual intolerance to progesterone and auxiliary ingredients. The following pathological conditions also become contraindications to the use of Progestogel:

• fibrocystic mastopathy in nodular form;
• formation of tumors of unknown origin in the mammary glands.

Treatment of patients with severe pathologies of the liver and kidneys is supervised by a doctor. Relative contraindications to Progestogel therapy are:

• ectopic pregnancy;
• porphyrin disease;
• vaginal bleeding of unknown origin;
• high blood pressure;
• endocrine diseases.

Be careful: there are contraindications

The hormonal agent is used with caution for circulatory disorders in the lower extremities. Especially with varicose veins and thrombophlebitis, the course of which is accompanied by thrombus formation.

Instructions for use

According to the instructions for use of Progestogel, the gel should be used as prescribed by a doctor. He calculates single and daily dosages and determines the duration of the upcoming treatment. The drug can be used in several ways depending on the diagnosed disease:

• daily;
• in the second phase of the menstrual cycle.

The rules and procedure for taking the drug are prescribed by the doctor.

Using Progestogel is quite simple. Each package contains an applicator for convenient dosing.

With its help, you can correctly measure the required amount of gel for a one-time application to the mammary glands. Before the procedure, wash the skin and dry it with a cotton towel.

Then you need to distribute a thin layer of the product on the mammary glands and rub in with massaging movements.

Progestogel should be applied up to 2 times a day. It is advisable to smear it before bed after hygiene procedures. At night, all biochemical processes in the body accelerate. The duration of the therapeutic course does not exceed 1 month. After consultation with a doctor, it can be extended for a few more weeks.

Overdose

Since progesterone enters the systemic bloodstream in low concentrations, no cases of overdose have been observed. If Progestogel gets inside, digestive and peristaltic disorders may occur. You should quickly rinse your stomach, take enterosorbent (activated carbon, Smecta) and seek medical help.

Side effects

More often, side effects of Progestogel are observed when the dosage regimen is violated or long-term treatment. Clinically, they are manifested by decreased sexual desire and irregular uterine bleeding.

There may be increased discomfort in the mammary glands and slight enlargement of the lymph nodes. Allergic reactions, both local and systemic, are less commonly diagnosed.

Their development is indicated by headaches, fever, facial swelling, and gastrointestinal disorders.

The drug has side effects

special instructions

Progestogel is a hormonal drug, so it should be used with caution. If any side effect occurs, stop using the gel and consult a doctor. He will adjust the dosage regimen or prescribe a drug with a different active ingredient.

A doctor’s consultation is also required if Progestogel is unsuccessful for 5-7 days. If the severity of pain does not decrease, the gel can be excluded from the therapeutic regimen. If it is necessary to use a hormonal drug, the doctor may prescribe drugs with an analgesic effect.

The use of progesterone does not affect memory, attention, or concentration. Therefore, there is no need to give up driving during Progestogel therapy. The instructions for use recommend not to stay in the open sun for a long time during the treatment period.

Pregnancy and lactation

Progestogel can be used in the early stages of pregnancy, but only if safer means are ineffective.

Before prescribing it, the benefits to the mother and the risk to the intrauterine development of the fetus are taken into account. It is prohibited for use in the 2nd and 3rd trimesters of pregnancy.

The manufacturer did not provide clinical trial results confirming the absence of teratogenic effects.

Not suitable for use during pregnancy

In case of urgent need, Progestogel can be used during lactation. Therapy is carried out under medical supervision with constant laboratory monitoring of the condition of internal organs.

Storage conditions and periods

The shelf life of the drug is 3 years. Once the tube is opened, it is recommended to use it for several months. Progestogel should be stored at room temperature in a dark place. If the gel separates, the smell changes, or a yellowish tint appears, it is prohibited to use it for treatment. The hormonal drug should be inaccessible to small children.

Conditions for dispensing from pharmacies

Progestogel is dispensed from pharmacies upon presentation of a prescription from a doctor.

Drug interactions

The gel combines well with other drugs - vaginal suppositories, ointments, tablets, creams. It should be taken into account that when combining hormonal contraceptives with Progestogel, its effect is enhanced.

Price

The price of Progestogel gel varies slightly in different pharmacy chains. The average cost of the drug is 780 rubles.

Analogs

Progestogel gel analogues are active and structural. Drugs with a similar composition include Utrozhestan and Progesterone. Iprozhin, Prajisan, and Crinon have similar therapeutic properties. A cheaper analogue is Progesterone, but only a doctor can replace Progestogel with it.

Analogs and similar drugs

Expert opinion

Lyudmila Sheveleva, pharmacist

Progestogel is one of the most effective drugs used in the treatment of diffuse fibrocystic mastopathy.

It copes well with engorgement and discomfort characteristic of mastodynia. The drug is used simultaneously for both etiotropic and symptomatic monotherapy.

This allows you to reduce the pharmacological load on a woman’s body.

But Progestogel should be used to eliminate pain in the mammary glands only as prescribed by a doctor. Cancer of the genital organs and breasts exhibits similar signs. In such cases, the use of antitumor agents is required.

Reviews

Valentina, Rostov-on-Don

Due to menstrual irregularities, I was diagnosed with fibrocystic mastopathy. The doctor prescribed Progestogel gel, reviews of which on specialized websites are mostly positive. I used the drug for a month, but the pain and swelling of the mammary glands disappeared within a week.

Inna, Petrozavodsk

I will also leave my review about the effect of Progestogel gel for mastopathy. At first I was very afraid to use the drug after learning about its hormonal origin. But during the treatment, no adverse reactions occurred, and Progestogel removed all symptoms of mastopathy after 2-3 days. The soreness of the gland, which worsens before menstruation, and bloody discharge from the nipple have disappeared.

Source: https://mydoctorok.ru/mazi/prozhestozhel-gel.html

Is Progestogel gel effective for mastopathy: description of the drug, its composition and action + reviews from women

Mastopathy is a very common disease. The disease occurs in 40% of women under 30 years of age and in 60% of older women.

Moreover, women who have gynecological pathologies are diagnosed with mastopathy several times more often.

The disease does not go away on its own; treatment of mastopathy can be conservative or surgical. A mammologist diagnoses and treats the disease.

In the drug treatment of pathology, Progestogel is often prescribed. This is what will be discussed in this article.

What is mastopathy

The term “mastopathy” combines a large group of breast diseases.

These pathologies are distinguished by morphological characteristics:

• fibrous;
• cystic;
• proliferative and so on.

Such changes in the mammary gland can be present either individually or simultaneously.

In fact, mastopathy is a benign pathology in which there is a pathological relationship between epithelial and connective tissue.

A similar phenomenon occurs when neurohumoral regulation is disrupted. That is, the disease can occur not only when hormones are imbalanced (estrogen, progesterone, prolactin), but also when the functioning of the nervous system is disrupted.

Associated symptoms

The main symptoms of mastopathy are the following:

• pain in the mammary gland . It can be local or radiate to the shoulder and scapula;
• feeling of discomfort - fullness, heaviness, engorgement, increased sensitivity of the mammary gland;
• nipple discharge . At the initial stage, discharge appears when pressure is applied to the nipple; in more advanced cases, the secretion is released spontaneously;
• the presence of fine-grained or large single neoplasms that a woman can independently palpate in the breast.

When an inflammatory process occurs, the general or local temperature may increase, and the axillary and subclavian lymph nodes may enlarge.

Causes

Most often, the cause of mastopathy is a hormonal imbalance in the body.

The following factors can provoke this phenomenon:

• too early (before 12 years) or too late (after 16 years) formation of the menstrual cycle;
• late onset of sexual activity (after 30 years);
• early (before 45 years) or late (after 55 years) menopause;
• late (after 30 years) first pregnancy;
• infertility;
• abortions;
• too short (less than 5 months) breastfeeding of the child or complete absence of lactation;
• hereditary predisposition;
• chronic inflammatory processes in the genital organs;
• menstrual irregularities;
• endocrine pathologies;
• prolonged stress;
• poor nutrition;
• bad habits;
• negative influence of the external environment.

Description of the drug

• Progestogel is a progesterone-based gel that can block estrogen receptors.
• The drug is applied topically, and in the area of ​​its application a local concentration of progesterone is created, which does not penetrate into the general bloodstream, and, therefore, does not change the general hormonal background of a woman.
• The action of the drug is based on:

• reducing the proliferative effect on the mammary gland;
• decreased absorption of fluid from tissues, which leads to decreased swelling;
• Natriuretic effect – removal of excess fluid.

Since mastopathy is a disease that develops when estrogen levels increase and progesterone levels decrease, to improve a woman’s condition and fight the disease, it is necessary to return these hormonal units to the correct balance.

Progestogel is a drug that locally increases the concentration of progesterone, therefore, the level of estrogen drops. Therefore, this drug is often prescribed for mastopathy.

Progestogel is a fairly effective remedy for the treatment of mastopathy. The gel is absorbed by only 10% of the total applied dose, which means it does not penetrate into the systemic circulation and is not metabolized in the liver.

Therefore, negative side effects from the drug are minimal and can only be observed in the form of a local reaction. According to studies, maximum absorption of progesterone occurs an hour after using the drug.

Progestogel is prescribed to patients for all types of mastopathy, except for the nodular form, since this form is mainly treated surgically.

The effectiveness of the gel is enhanced when taking oral contraceptives.

Operating principle

The principle of action of the drug is due to progesterone, which is part of it.

Progesterone blocks estrogen receptors, as a result of which excess fluid is absorbed faster and swelling subsides. In addition, the pressure on the milk ducts is reduced, which leads to a decrease in the soreness of the gland.

At the same time, progesterone blocks prolactin receptors, which reduces the process of maintaining lactation.

Thus, Progestogel eliminates the negative impact of estrogen and prolactin on breast tissue, removes excess fluid and relieves the patient from swelling and pain.

Indications and instructions for use

Progestogel is prescribed in the following cases:

• mastalgia and mastodynia – pain and discomfort in the mammary gland, swelling, increased sensitivity when touched;
• diffuse fibrocystic mastopathy - proliferation of fibrous and cystic compactions.

When taking hormonal drugs simultaneously, the effect of Progestogel may be enhanced, therefore the systemic absorption of the drug is reduced, as a result of which an overdose is almost completely eliminated.

The drug is applied to the mammary gland using a dispenser. 1 application should be 2.5 grams of gel. Using gentle movements, rub the gel into the skin until completely absorbed.

Frequency of application – 1-2 times a day. As prescribed by the doctor, the gel is used either daily or in the second phase of the cycle - from 16 to 25 days. The course of treatment is 3 cycles.

Contraindications and side effects

This drug is not used for:

• nodular form of mastopathy;
• tumors in the mammary gland of unknown etiology;
• 2nd and 3rd trimester of pregnancy;
• malignant pathologies;
• individual sensitivity to the components of the product.

The ointment is used with caution when:

• renal failure;
• diabetes mellitus;
• vaginal bleeding;
• bronchial asthma;
• liver failure;
• ectopic pregnancy;
• predisposition to thrombosis;
• acute form of phlebitis;
• thromboembolic diseases;
• arterial hypertension;
• epilepsy;
• breast fibroadenoma;
• porphyria.

The duration of treatment is determined by the doctor individually. But on average, the therapeutic course is 3 menstrual cycles.

In rare cases and in case of overdose, the following may occur:

• increased tenderness of the mammary glands;
• rushes of blood to the site of application of the gel;
• decreased sex drive;
• intermenstrual bleeding;
• nausea;
• fever;
• allergies.

Analogues of the drug

Analogues of Progestogel gel are the following preparations containing progesterone as an active component:

• Utrozhestan;
• Prajeesan;
• Iprozhin;
• Crinon;
• Progesterone.

Reviews from women

Below are reviews of women who used Progestogel for treatment of mastopathy:

Conclusion and conclusions

When treating mastopathy, it is necessary first of all to eliminate the cause of the pathology that caused changes in the breast tissue.

Progestogel is a gel for local treatment of the problem, but it cannot eliminate the cause of mastopathy in all cases, so complex treatment is necessary.

Source: https://zhenskoe-zdorovye.com/mammologija/mastopatiya/lechenie-mas/prozhestozhel.html

How to use Progestogel ointment for mastopathy?

Treatment of fibrocystic mastopathy of the mammary gland is a complex treatment consisting of proper nutrition, taking vitamins, as well as the use of internal and external medications. Ointment for mastopathy "Progestogel" is an external gestogen and acts locally on the affected areas. The drug is prescribed directly by the doctor, after a complete examination and diagnosis of the patient.

 Pharmacological properties of Progestogel for mastopathy

Cream for mastopathy "Progestogel" is used to increase the amount of the hormone progesterone in the blood.

It is responsible for blocking prolactin receptors and reducing the level of active estrogens, which cause the appearance of cysts and lumps in the mammary gland in fibrocystic mastopathy.

The drug acts on the problem locally, without having a systemic effect on the organs and without being absorbed into the blood. After application, the ointment penetrates through the skin into the blood vessels, thereby reducing capillary permeability. This leads to a decrease in symptoms.

The ointment also has a slight natriuretic effect, preventing fluid stagnation in the mammary glands, while reducing swelling and an increase in tumors.

Thanks to the external use of Progestogel ointment for mastopathy, the required level of progesterone in the blood is achieved, which makes it possible to reduce the hormonal load on the body when taking oral medications and injections. A tenth of the applied dose is absorbed. This way, negative side effects can be avoided. After performing its functions, “Progestogel” is excreted from the body through the kidneys and bile.

In women, after using the drug, subjective and objective results are observed. The first include:

• reduction of anxiety and depression;
• reducing the feeling of heaviness in the chest;
• reduction of negative PMS symptoms.

Objective results after applying the gel for mastopathy “Progestogel”:

• resorption of compactions in the mammary glands;
• reduction of swelling and inflammation;
• free release of fluid from tissues;
• stopping the growth of cysts.

Complete cure can only be achieved with the use of a complex of drugs, including traditional medicine.

Compound

Progestogel ointment for mastopathy contains the main active ingredient progesterone at a concentration of 1%. The drug also contains auxiliary components:

• ethanol;
• hydrogenated castor oil;
• trolamine (triethanolamine);
• octyl;
• octyldodecanol;
• carbomer 980;
• distilled water.

Progestogel ointment is available in 80 g quantities in aluminum tubes, hermetically sealed at one end

The kit includes a plastic spatula for convenient application of the required dose of the drug to the skin. One dose of 2.5 g contains 0.025 g of progesterone.

Indications for use of the gel for Progestogel mastopathy

The drug is prescribed by a mammologist to patients of different age categories as one of the components of complex treatment. Almost all of them, after use, noted a positive therapeutic effect after just a few uses.

Unpleasant sensations in the chest area can occur both with fibrocystic mastopathy and due to other reasons, as a result of which the hormone progesterone decreases:

• PMS;
• puberty;
• pregnancy;
• menopause;
• abortion;
• taking oral contraceptives.

Such conditions are called mastodenia.

“Progestogel” for mastopathy is prescribed in the following cases:

• increased sensitivity and soreness of the mammary glands;
• inflammatory process due to the appearance of neoplasms in glandular tissues;
• to reduce the development and spread of fibroids.

The dosage and duration of treatment is calculated by the doctor in each case individually. You should never use hormonal medications without consulting a mammologist or gynecologist.

How and how much to apply gel for Progestogel mastopathy, instructions

“Progestogel” is an external preparation and is applied to the skin, in the area where inflammation is localized. The dosage is prescribed by the doctor depending on the stage of development of the disease and the woman’s hormonal levels. This is very important, because with an increased dose, an excess of progesterone may occur, which will lead to side effects and unwanted reactions of the body.

Before the procedure, the breasts are cleaned and dried. A certain amount of the product is squeezed onto a spatula and applied to the inflamed area of ​​the mammary gland. Rub the ointment in a circular massage motion, trying not to press too hard or touch the area of ​​the areola and nipples. The same is done on the second breast.

Only after the drug is completely absorbed can you wear underwear. Progestogel is used for mastopathy 1-2 times a day for exactly the number of days prescribed by the doctor. Basically, this period lasts up to 3 menstrual cycles. After re-examination, a decision is made to continue or discontinue treatment.

It is important at the time of application to prevent exposure of the treated area to direct sunlight and UV rays. For this purpose, it is not recommended to visit beaches and solariums. Clothing should cover the chest area, shoulders, and armpits.

Side effects

As with any drug, the use of Progestogel can cause unwanted reactions in the body. This happens due to intolerance to the components of the ointment or non-compliance with medical prescriptions. But because The dose and compatibility are determined by the mammologist; side effects are extremely rare. In some cases this is:

• decreased libido;
• a feeling of heat alternating with a feeling of cold;
• nausea and dizziness;
• headache;
• swelling of the lips and neck;
• the appearance of lumps in the chest;
• irritation, redness and itching;
• uterine bleeding between main cycles;
• fever.

In case of overdose, the patient may experience anaphylactic shock. If one or more adverse reactions occur, you should stop using the drug and consult a doctor.

Use of Progestogel during pregnancy and breastfeeding

To date, the clinical effect of the drug on the fetus during pregnancy and on the newborn during lactation has not been fully studied. The ointment is prescribed up to 12 weeks of gestation and only if the effect of its use is higher than the expected threat to the unborn baby.

During the lactation period, Progestogel can reduce the production of prolactin, which affects the amount of milk

But the whole problem is that during the inflammatory process, an infection can enter the mammary glands and be transmitted to the child at the time of feeding.

Therefore, after weighing the pros and cons, a decision is often made to prescribe and transfer the newborn to artificial nutrition.

If the mother is categorically against this outcome, the gel is combined with Bromocriptine, and after each use, milk is expressed an hour later.

Contraindications

After clinical examinations, the doctor determines the possibility of using Progestogel. Contraindications include:

• pregnancy after 12 weeks;
• breast tumor of unknown etiology;
• malignant formations;
• nodular form of mastopathy.

The drug can be used, but with caution in patients with the following diseases:

• renal and liver failure;
• bronchial asthma;
• epilepsy;
• thrombophlebitis;
• depression;
• arterial hypertension;
• diabetes.

The drug does not affect the ability to drive a car or operate machinery.

Drug interactions with other drugs

The combined use of Progestogel with combined hormonal contraceptives can enhance the effect of the first. In this case, there is a need to temporarily stop taking contraceptives and search for an alternative. Progestogel cream is not prohibited from being used in conjunction with other medications intended for the treatment of mastopathy and related diseases.

Analogs

The need to replace Progestogel with similar drugs appears when the patient develops diseases with a hormonal etiology or when urticaria is detected at the site of treatment of the breast with the gel.

The search for an alternative medicine should be based on the characteristics of the disease, its stage, and individual reactions to the contained components.

External agents for fibrocystic mastopathy, which have the same therapeutic properties, can be in different dosage forms. These include:

• Utrozhestan is a drug for oral administration. Available in the form of yellow gelatin capsules. Intended for the production of secret endometrium and restoration of hormonal levels;
• Iprozhin - tablets for oral and intravaginal administration, prescribed for hormonal therapy for infertility, in combination with estrogens during menopause;
• Crinon is a vaginal gel used for diseases caused by a lack of progesterone;
• Susten (solution) - progesterone is absorbed in the gastrointestinal tract, detected in the blood plasma an hour after administration, and its maximum concentration is observed after 3 hours.

Utrogestan is the main analogue of Progestogel

Only the doctor determines which analogue to replace with. Self-selection of medications containing hormones and their uncontrolled use can lead to serious consequences.

The advantages of the Progestogel gel include its ability to quickly relieve symptoms with minimal risk of adverse reactions. Affordable price and convenient application make it a favorite among hormonal agents for fibrocystic mastopathy.

Source: https://MamaZdorova.ru/maz-prozhestozhel-pri-fibrozno-kistoznoj-mastopatii-02/