Omnitus cough syrup: instructions for use of the drug

A person may develop a cough due to a respiratory infection, respiratory tract disease, or allergy. This is a rather unpleasant symptom, especially when the cough is dry. To get rid of this condition, special medications are needed.

They are selected by the doctor depending on the patient’s condition. Quite often, Omnitus syrup is prescribed for dry coughs. The instructions recommend using it for children over 3 years of age and adults.

It is best to use the drug as prescribed by a doctor, as there are certain contraindications to its use.

general characteristics

The instructions for Omnitus syrup classify it as an antitussive drug. It acts directly on the cough center, but has nothing to do with narcotic drugs.

In addition, the main active ingredients of the drug penetrate into the bronchi and have an anti-inflammatory and bronchodilator effect there.

As a result, the cough becomes more productive and mucus begins to be coughed up.

Therefore, it is recommended to get rid of a dry cough faster or transfer it to a more productive one - wet. There are not many drugs that would have such an effect; complex therapy is usually needed.

Or “Omnitus” is prescribed.

This drug is produced in Serbia by the international company Hemofarm. The product is available in the form of tablets and syrup.

Children are most often prescribed a liquid form, because this is how the main active ingredient is more easily absorbed, better tolerated and eliminated from the body faster. The syrup is a transparent viscous liquid.

It is sweet and has a slight vanilla scent. The drug is packaged in dark glass bottles and equipped with a 5 ml measuring spoon.

The composition of Omnitus syrup is such that there are rarely allergic reactions to it, since it contains only one active ingredient - butamirate citrate. It is contained in an amount of 0.8 mg per 1 ml. Auxiliary components are needed only to give the preparation the desired consistency and a pleasant sweetish taste. These are sorbitol, saccharin, vanillin, anise oil, glycerol and ethanol.

Features of the action

Omnitus cough syrup is a new generation drug. It relieves dry cough and effectively removes mucus from the bronchi. The active ingredient in the syrup directly affects the cough center in the brain. But it has a complex effect:

• has anti-inflammatory properties, therefore relieves fever, reduces pain and swelling in the bronchi;
• relaxes the smooth muscles of the bronchi, dilates them and facilitates breathing;
• inhibits the cough reflex, reduces its excitability;
• relieves irritation from the mucous membranes of the respiratory tract;
• thins mucus;
• accelerates the evacuation of mucus from the lower respiratory tract;
• enriches the blood with oxygen.

Indications for use

Omnitus cough syrup is prescribed mainly to children. This form is also preferable when the patient cannot swallow the tablet. The main indication for use of the drug is the presence of a dry cough. Moreover, it can be caused by various pathologies. The instructions for Omnitus syrup recommend its use in the following cases:

• with ARVI;
• with the flu;
• with whooping cough;
• for acute bronchitis;
• to suppress the cough reflex before surgery or bronchoscopy.

Basically, Omnitus syrup is intended to relieve acute cough. If it is chronic, complex therapy prescribed by a doctor is necessary. After all, butamirate can eliminate a cough, but will not get rid of its cause, so the disease will return again.

When not to take syrup

Omnitus syrup is mainly prescribed for children over 3 years of age. But before starting to use the drug, it is necessary to exclude conditions that may become a contraindication to taking the syrup. First of all, these are allergic reactions and individual intolerance to the components of the product. If any negative reactions occur, the drug must be discontinued.

In addition, Omnitus is not used for patients with renal failure or any other pathologies of the urinary system. Due to the presence of a small amount of ethyl alcohol in the syrup, patients with impaired liver function, epilepsy and other abnormalities in the central nervous system should take it with caution.

Taking Omnitus syrup during pregnancy should be carried out according to strict indications and under the supervision of a doctor. In the first trimester, it is generally prohibited to use it, since butamirate penetrates the placenta and can negatively affect the development of the child. In later stages, the drug is used only when absolutely necessary. You should not drink Omnitus while breastfeeding.

Possible side effects

If you follow all the doctor's recommendations and the exact dosage of the drug, negative reactions to it are rare. "Omnitus" affects the cough center, but does not change respiratory functions and does not depress the functioning of the central nervous system, unlike opium drugs.

Therefore, side effects occur only in cases of individual intolerance to the components of the product. An accidental overdose is also possible, as a result of which negative phenomena can also be observed.

The most common side effects include:

• allergic reactions on the skin;
• nausea, abdominal pain;
• intestinal disorder;
• apathy, drowsiness;
• impaired coordination of movements;
• dizziness, headaches;
• decrease in blood pressure.

Syrup "Omnitus": instructions for use

The drug is prescribed by a doctor depending on the characteristics of the disease, the individual condition of the patient and age. Although the instructions recommend the required daily dose, it is determined mainly individually.

Most often, the dosage of Omnitus syrup is calculated based on the patient’s body weight. Moreover, measuring the required amount is easy, since the kit includes a special measuring spoon.

The following dosage is usually recommended:

• children under 6 years of age or weighing up to 22 kg need 10 ml per dose, this is 2 measuring spoons, they should be given 3 times a day;
• from 6 to 9 years old, with a weight of up to 30 kg, 3 scoops are prescribed, which is 15 ml, also three times a day;
• children over 9 years old need 3 spoons, but 4 times a day;
• Adult patients need to take 6 spoons three times a day.

Usually the drug is taken for 5 days. If the patient does not feel better during this time, it is necessary to consult a doctor to prescribe another medicine. It is not recommended to extend the course of treatment on your own.

Special instructions for taking the drug

Omnitus syrup can only be taken as prescribed by a doctor. In addition to possible side effects from its use, there may be negative consequences when using it in complex therapy.

Due to the peculiarities of the action of the active substance of the drug, it cannot be prescribed together with antitussives.

In addition, Omnitus should not be used in combination with sleeping pills, tranquilizers and other drugs that depress the central nervous system. It is not recommended to drink alcohol during treatment. But people with diabetes can use the syrup. It contains no sugar, only diabetic-friendly sweeteners.

Analogues of the drug

There are several similar drugs whose active ingredient is butamirate. They can be available in the form of tablets or syrup. The choice of drug should be made by a doctor, since they differ in the dosage of the active substance and the method of administration.

• Codelac Neo is also available in syrup or drops. Contains slightly less butamirate.
• "Panatus" is a complete analogue of "Omnitus", but is intended only for children, as it contains only 4 mg of butamirate.
• You can use the Swiss drug "Sinekod", also used for dry cough.

Syrup "Omnitus": reviews

The high effectiveness of the drug and its availability make it one of the most popular remedies for the treatment of dry cough. In pharmacies, this syrup is sold without a doctor’s prescription, and its cost ranges from 170 to 250 rubles.

Parents of sick children really like that the drug is well tolerated, rarely causes side effects and helps quickly. Within 1.5-2 hours after taking the first dose, the cough subsides and the child breathes easier. Doctors also often prescribe Omnitus syrup. Reviews from experts generally note its high efficiency.

It quickly makes cough productive, relieves inflammation, and makes breathing easier.

Source: https://www.syl.ru/article/355794/sirop-omnitus-instruktsiya-po-primeneniyu-pokazaniya-sostav-otzyivyi

How to take omnitus cough syrup

Let's consider the specifics of the composition and action of this medicine in the form of syrup, the instructions for use of which will be useful for the effective treatment of throat diseases, acute respiratory viral infections, lungs and bronchial exacerbations.

Compound

The composition of Omnitus syrup includes the main ingredient regulating the patient's condition - butamirate citrate in a volume of 0.8 milligrams per 1 milliliter. All other components perform an accompanying function and sweeten, providing a pleasant taste. These include:

Omnitus syrup is produced by the Serbian company Hemofarm and is supplied to the market in tablets and liquid form. The consistency of the medicine looks like a transparent viscous liquid syrup. The drug tastes sweet, with the presence of vanillin. Supplied in brownish glass bottles; for convenience, the package includes a 5-milliliter measuring spoon.

How does it work for dry cough?

Omnitus dry cough syrup is used during colds, flu, whooping cough and inflammatory processes against the background of other viral diseases.

The effect of taking the liquid form of the medicine is quick and painless. Containing no narcotic substances and not causing addiction, the drug easily penetrates the patient’s bronchi and has an anti-inflammatory and stabilizing effect.

The cough decreases immediately due to the reduction of the cough reflex in response to irritation. A bronchodilator effect is also observed. Blood oxygen saturation improves, which alleviates the patient's condition.

Omnitus dry cough syrup is taken within the calendar period prescribed by the doctor. It is important to follow a precise dosing schedule, since the medicine has its own cycle of action, absorption and excretion from the body through the kidneys (about 10 hours). The drug can be purchased without a prescription, as it does not contain codeine. The shelf life of the syrup is 5 years.

Instructions and method of use for adults

The instructions for use of Omnitus syrup contain all the necessary information that will serve as a guide to action in the treatment of dry cough and bronchial pain. Syrup can also be prescribed to relieve cough during preparation for surgery, before bronchoscopy and during the rehabilitation period after these procedures.

How to use?

The attending physician will prescribe Omnitus syrup, tell you how to take it, explain and prescribe the dosage. The daily dose is always very individual and depends on the age and condition of the patient. The reception will be comfortable using the measuring spoon that comes with the bottle. The taste of the syrup is pleasant, the medicine does not require drinking water.

Before or after meals?

The drug has increased absorption; during the first two hours after eating, the drug is absorbed most effectively and actively distributes throughout the tissues and systems of the body.

If you take Omnitus at night, it will help you sleep peacefully without coughing all night long.

Dosage

The drug is prescribed depending on the age of the patient. The syrup dosage is no more than 10 ml per time for children weighing up to 22 kilograms (three times a day). This volume corresponds to two measuring spoons. More detailed dosage:

• weight up to 30 kilograms and age up to 9 years: 15 milliliters (3 spoons 3 times a day);
• weight from 30 to 50 kilograms and age from 9 years: 15 milliliters (3 spoons 4 times a day);
• weight from 50 kilograms, adults: 15 milliliters (3 spoons 3 times a day).

Exceeding the dosage is highly discouraged due to possible intoxication of the body, especially in children.

How many days to drink?

It is not recommended to self-medicate and take Omnitus uncontrolled and for a long time. The decision on how many days to drink Omnitus syrup is made by the attending physician. Standard terms are up to 5 days. The doctor monitors the condition and determines whether to continue using the syrup or discontinue it.

Important Notes

Omnitus cough syrup, the instructions for which will provide the buyer with all the necessary information, should be taken only after a visit to the doctor and according to his recommendations. There are a number of side effects, as with any drug, that are important to anticipate and take into account.

The combination of syrup with other antitussive medications is highly undesirable. Omnitus also does not combine with sleeping pills, alcohol, or antipsychotics. Reception is possible in case of diabetes mellitus, since the composition does not include sugar and its compounds, but diabetic-safe sweeteners (sorbitol) are used.

• Nausea and vomiting are possible;
• dizziness, weakness;
• skin rashes, inflammation.

The drug is prohibited for use by pregnant women and while breastfeeding, since the effect of the drug during this time has not been fully studied. As a last resort, it is recommended to stop breastfeeding for treatment.

Due to the presence of ethanol in the composition, Omnitus syrup is contraindicated in chronic diseases of the liver, kidneys, cerebral pathologies, alcoholism, epilepsy, brain diseases, as well as in the treatment of pregnant women and children - prescription and treatment should be carried out under the supervision of a doctor.

• a sharp drop in pressure;
• prolonged vomiting;
• chronic constipation or diarrhea;
• constant dizziness.

If an overdose and other side effects are detected, symptomatic treatment is prescribed, adsorbents, laxatives or fixatives are taken.

Butamirate can also cause drowsiness, so driving a car or other vehicles is not recommended.

During the period of admission, you should refuse to perform work related to complex technologies and control of mechanisms.

Use in children

For children, the use of Omnitus syrup will be a real gift - the drug demonstrates good results for the treatment of young patients. However, it is worth taking into account that the drug is not intended for children under 3 years of age.

Read about the features of using Omnitus tablets for the treatment of cough in children in this article.

Review Reviews

Being an affordable medicine sold in various pharmacy chains, Omnitus syrup receives mostly positive reviews. This is a really popular antitussive.

According to parents, children tolerate the syrup and the effect very well; cough relief comes quite quickly. Just a couple of hours after the first dose, the cough becomes easier, the child breathes more freely.

There are practically no complaints about side effects.

What is better - syrup or tablets?

There is no difference in action between syrup and tablets, therefore, when answering the question of which is better, you can take into account the ease of use and contraindications of one or another form of release.

So, most often syrup is optimal for children, which will become a pleasant treatment option. When prescribing, take into account the composition: the tablets contain lactose, and the syrup contains ethanol. For some patients, these substances may be contraindicated. Tablets are prescribed to adolescents and adults, and if this form is not available in the pharmacy, they can be replaced with syrups.

Analogs

Omnitus syrup, like any other drug, has analogues. Today on the pharmaceutical market you can find several medicines in the form of syrup or capsules, which in their effects are very close to the drug in question. They are united by the same main base substance - butamirate. Among them are such well-known names as:

The difference lies in the dosage of butamirate, flavor shades and other substances. The closest analogue in composition can be called Panatus.

As an element of complex therapy for cough, antibiotics are usually prescribed.

Source: https://lkray-promo.ru/kashel/kak-prinimat-sirop-ot-kashlya-omnitus/

Omnitus cough syrup for children: instructions for use, dosage, reviews, analogues, price

Omnitus is an antitussive drug produced by Hemofarm, Slovenia. The medicine is used for dry, non-productive coughs of various natures. The drug has few contraindications and rarely causes side effects, but before starting therapy you need to read the instructions for using Omnitus.

Release form

One of the forms of release of Omnitus is syrup. In appearance, it is a colorless, transparent liquid that smells like vanilla.

The syrup contains butamirate citrate as the main component.

In addition to it, the medicine contains inactive components:

• anise oil;
• sorbitol;
• glycerol;
• sodium hydroxide;
• water;
• ethanol;
• vanillin;
• E 954;
• E 210.

In addition to syrup, you can find Omnitus tablets on sale, which come in 20 mg and 50 mg doses. The first are allowed for children over 6 years old, the second only for people over 18 years old, syrup from 3 years old.

Indications for use

The medicine Omnitus is a centrally acting antitussive drug. It suppresses the cough center, which is located in the medulla oblongata, and as a result the cough goes away. In addition, the medication expands the bronchi, suppresses the inflammatory process, improves lung function, and promotes oxygen saturation of tissues.

• The medication is recommended for children who have a dry, non-productive cough of various origins, including those arising from whooping cough, influenza and other diseases.
• It is also used to suppress cough before, during and after surgery, and for diagnostic studies of the bronchopulmonary system, such as bronchoscopy - examination of the bronchial tree using a special medical instrument.
• 

Important information! An antitussive should not be given to children with a wet or, as it is also called, a productive cough, when phlegm forms in the bronchi.

When the cough reflex is suppressed, it will stagnate in the respiratory tract and serve as a good environment for the proliferation of pathogenic microflora, which can lead to the development of pneumonia.

For diseases of the bronchopulmonary system, which are accompanied by a wet cough with difficult to separate sputum, you need to drink expectorants and mucolytics, such as Ambrobene, Lazolvan, ACC.

At what age can a child have Omnitus syrup?

According to the instructions for use, Omnitus syrup should not be given to a child under 3 years of age. At an older age, children should take the medicine with caution, since it contains ethyl alcohol.

Contraindications

Omnitus syrup should not be given to a child if he is allergic to its main and auxiliary components. Due to the ethyl alcohol content, it should be drunk with caution by patients who have:

• liver dysfunction;
• organic lesions of the central nervous system, including epilepsy.

The syrup contains no sugar, its sweet taste is given by sweeteners: sorbitol and saccharin, so the medicine can be used for children suffering from diabetes.

Instructions for use

Omnitus syrup can be given to children before or after meals. The dosage of the medication is selected depending on the weight and age of the child:

Age and weight of the patient Number of measuring spoons of medicine Volume of medicine in milliliters Frequency of administration per day

3-6 years or 15-22 kg	2	10	3
6-9 years or 22-30 kg	3	15	3
From 9 years or more than 30 kg	3	15	4

The pediatrician should decide how many days Omnitus should be given to the child, depending on the severity of the clinical picture.

During therapy, parents should remember the following:

1. To prevent the medicine from losing its therapeutic effect, it must be stored at a temperature of 15-25 degrees in a dry, dark place.
2. The shelf life of the syrup is 5 years from the date of release; after this time, the medicine must be disposed of.
3. Do not exceed the therapeutic dosage of the medication, otherwise this will lead to an overdose of the antitussive drug. In case of drug poisoning, nausea, vomiting, drowsiness, stomach upset, dizziness occur, and a possible drop in blood pressure occurs. In case of an overdose of medicine, you must call an ambulance. Before her arrival, it is recommended to lay the victim on his side so that if the pressure drops, he does not fall and get injured. In case of an overdose of syrup, the child should not lie on his back, otherwise he may choke when vomiting. If possible, the victim can be given an enterosorbent, for example, Smecta, Neosmectin, Enterosgel. These medications are allowed from birth. You can give a saline laxative. In case of overdose with butamirate-based medications, the antidote is unknown, so symptomatic therapy is prescribed if necessary.
4. During treatment, you should not give your child other drugs containing ethyl alcohol, medications that depress the nervous system: sleeping pills, antipsychotics, tranquilizers.

Adverse reactions

Omnitus syrup is usually well tolerated by children, but sometimes it can provoke a number of undesirable reactions. During treatment the following may occur:

• dizziness;
• allergy;
• rashes;
• loose stools;
• drowsiness;
• nausea.

If the listed reactions occur during therapy or undesirable effects not described in the instructions occur, you should consult your pediatrician; he may cancel the syrup or replace it with another.

Price

The cost of the medicine may vary depending on the specific pharmacy. The price of Omnitus in syrup is about 150 rubles.

Analogs

There are analogues of Omnitus and its substitutes for sale according to the pharmacological group:

• Sinecode;
• Codelac Neo;
• Stoptussin;
• Codelac.

Omnitus or Sinecode: which is more effective?

Sinekod contains butamirate as its main component. It is produced not only in syrup, which is approved for children over 3 years of age, but also in drops, which are suitable for babies over 2 months old. In addition, it differs from Omnitus in terms of shelf life, storage conditions, and price.

Sinekod does not lose its properties for 3 years from the date of production. The drug should be stored, regardless of the form of release, in a damp place, protected from light at temperatures up to 30 degrees. Sinekod costs more.

Otherwise, both antitussives are similar, and after consultation with a pediatrician, you can take any of these medications.

Is Codelac Neo for a child or Omnitus better?

Codelac Neo has the same active substance, similar indications, contraindications and adverse reactions. This is a Russian drug that is commercially available in drops, syrup and tablets.

It differs from Omnitus in the composition of auxiliary products and shelf life (for Codelac Neo it is 36 months). For dry cough, babies over 2 months of age should take Codelac Neo drops.

Children older than this age can be treated with Omnitus or Codelac Neo in syrup.

Is Omnitus or Stoptussin more effective?

Stoptussin is a combination drug, one of the active ingredients of which is butamirate. The medicine is available for sale in drops (allowed from 6 months) and tablets (allowed from 12 years).

Compared to Omnitus, the combined product has more contraindications. It should not be taken by patients with myasthenia gravis.

Stoptussin also causes more side effects, but this does not mean that it is worse, since it may be the one that is suitable for a particular patient.

Is Omnitus or Codelac better for a child?

Codelac is a substitute for Omnitus in its pharmacological group. The antitussive effect of it is explained by codeine, which causes mental and physical dependence. Codelac is a narcotic drug that is subject to quantitative registration and is sold strictly according to a prescription and only in pharmacies that have a license permitting the sale of such medications.

Reviews

Moms and dads opinion

Parents leave positive and negative reviews about Omnitus baby syrup. Among the advantages they note the following:

• The drug helps well with dry cough, it becomes less frequent.
• The medicine tastes sweet and has a pleasant smell, so most children drink the syrup well.
• To open the syrup, you first need to press the lid, then turn it counterclockwise, which is not possible for a small child to do. This reduces the likelihood of an overdose if the baby finds the medicine and wants to take it himself.

Negative reviews are due to the fact that the child may be allergic to Omnitus. Some parents write that the syrup is ineffective; they give it for a dry cough in order for it to become moist and end.

Preparations based on butamirate cannot be used because they cause mucus to appear in the respiratory tract.

They suppress the cough reflex, and in order for a cough to change from dry to wet, you need to take medications from a different group: mucolytics and expectorants.

Opinion of Evgeny Komarovsky

Evgeniy Olegovich takes the antitussive medicine well. But he believes that the only time you can drink it is a dry cough, which is observed against the background of whooping cough. In other cases, taking it can be dangerous. Due to treatment, the cough reflex is suppressed, and phlegm will accumulate in the respiratory tract, which can lead to inflammation of the bronchi or lungs.

A well-known pediatrician urges parents not to self-medicate. If a cough appears, Evgeniy Olegovich recommends contacting a doctor who will examine the child, listen to him and, if necessary, prescribe an antitussive drug.

Although the syrup can be purchased without a prescription, it should not be given to a child without consulting a pediatrician. Only a specialist, after examining the patient, can decide on the advisability of treatment with this drug and tell how to take Omnitus.

Source: https://vospitulya.ru/razvitie-detey/zdorovye/lekarstva/omnitus-sirop.html

Omnitus

One tablet of the drug Omnitus contains 20 or 50 mg of butamirate citrate and such inactive excipients as: lactose monohydrate, hypromellose, magnesium stearate, talc, colloidal anhydrous silicon dioxide, povidone. The composition of the film shell includes: ethylcellulose, hypromellose, talc, macrogol, titanium dioxide and yellow dye E110 “Sunset”.

1 ml of syrup contains 0.8 mg of butamirate citrate and auxiliary inactive substances: non-crystallizing sorbitol 70%, glycerol , sodium saccharinate, benzoic acid, anise oil, vanillin, ethanol 96% sodium hydroxide and distilled water.

Release form

Omnitus is available in modified-release film-coated tablets with a dosage of the active substance of 20 or 50 mg, yellow or orange in color, round biconvex shape, and also in the form of syrup.

• The tablets are packaged in PVC or aluminum blisters of 10 pieces, there is 1 blister in a cardboard box, while the syrup is sold in 200 ml bottles made of dark glass, sealed with a plastic cap and tamper evident.
• The syrup is supplied with a 5 ml measuring spoon with a 2.5 ml line. One cardboard box contains 1 bottle.

pharmachologic effect

It has anti-inflammatory, bronchodilator, antitussive and expectorant effects.

Pharmacodynamics and pharmacokinetics

Omnitus is a centrally acting antitussive drug.

The active substance has no chemical or pharmacological similarity to opiates and acts directly on the cough center , which has an expectorant, moderate bronchodilator and anti-inflammatory effect, improves spirometry (external respiration tests) and blood oxygenation .

Pharmacokinetics

• Absorption : absorption is high. Taking 150 mg of syrup can cause a maximum plasma concentration of the main metabolite - 2-phenylbutyric acid - 6.4 μg/ml after 90 minutes, 50 mg tablets - after 9 hours - 1.4 μg/ml.
• Metabolism : hydrolyzed in plasma to 2-phenylbutyric acid and diethylaminoethoxy-ethanol . Next they bind to plasma proteins , then the main metabolite undergoes oxidation. The drug does not accumulate in the body.
• The half-life of butamirate citrate when taking syrup is 6 hours, when taking 50 mg tablets - 13 hours. Excretion occurs through the kidneys. Acidic metabolites are eliminated primarily as glucuronides .

Indications for use

• Dry cough of any origin, including those arising from colds, whooping cough or flu .
• Cough suppression in the pre- or postoperative period, for surgical procedures and bronchoscopy .

Contraindications

• breast-feeding;
• hypersensitivity to any component included in the drug;
• pregnancy;
• up to 6 years of age Omnitus is contraindicated in 20 mg tablets;
• The 50 mg dosage is contraindicated for persons under 18 years of age.

Unlike tablets, syrup cannot be used only in the first trimester of pregnancy and in children under 3 years of age.

Side effects

Regarding the digestive system: nausea and diarrhea .

, the following body reactions were noted: dizziness , exanthema and various manifestations of an allergic reaction .

Instructions for use of Omnitus (Method and dosage)

The drug must be taken orally, without chewing, before meals.

According to the instructions for use of Omnitus tablets , their use depends on the age of the patient:

• 20 mg – adults should take 2 tablets. 2 or 3 times a day, patients aged 6-12 years are prescribed 1 tablet. twice a day, from 12 years old, 1 tablet three times a day;
• 50 mg - adults are recommended to take 1 tablet every 8-12 hours.

Instructions for use of Omnitus syrup suggest using a 5 ml measuring spoon. The dosage is different for different age categories:

• adults and elderly people - 30 ml (corresponds to 6 measuring spoons) 3 times during the day;
• from 9 years (child weight 40 kg) - 15 ml (corresponds to 3 measuring spoons) 4 times during the day;
• 6-9 years (weight 22–30 kg) - 15 ml (corresponds to 3 measuring spoons) 3 times during the day;
• 3-6 years (weight 15-22 kg) - 10 ml (corresponds to 2 measuring spoons) 3 times during the day.

Overdose

An overdose is manifested by the following symptoms: nausea accompanied by vomiting , diarrhea , as well as dizziness or drowsiness , decreased blood pressure .

As treatment, activated charcoal and a laxative and, if necessary, symptomatic therapy is recommended.

Interaction

At the moment, drug interactions with butamirate have not been described.

Terms of sale

A prescription is not required to purchase the drug.

Storage conditions

In a dry, dark place. Temperature 15–25° Celsius.

Attention! For the safety of your children, keep the drug out of reach.

Best before date

The tablets are valid for two years from the date of release of the drug, and the syrup for five years.

special instructions

A standard single dose of 10 ml syrup contains 0.03 ml of ethanol, which should be taken into account when prescribing the drug to patients with liver or brain diseases, alcoholism , epilepsy , since treatment may pose a health hazard.

When treating with Omnitus, you should not prescribe drugs that can depress the central nervous system, for example: tranquilizers , sleeping pills , antipsychotics . In addition, patients should refrain from drinking alcohol.

Analogs

Level 4 ATX code matches: Libexin Codelac Neo Sinecode

• Codelac Neo
• Panatus
• Sinekod

Reviews about Omnitus

Numerous reviews of Omnitus tablets as an antitussive drug indicate the effectiveness, demand and availability of this product.
However, many use it in combination and note some negative aspects, expressing themselves as follows: “It helps, I stopped drinking - the cough appeared again,” “Why are dyes needed in medicines? They only cause harm."

Reviews about the syrup are positive; many people like its pleasant smell and taste, the possibility of using it for children, and its affordable price.

Omnitus price, where to buy

On average, the price of Omnitus syrup is 145-170 rubles.

Tablets with a dosage of 20 mg cost 120-260 rubles (10 tablets per package), while 50 mg costs 230-250 rubles (10 tablets).

Source: https://medside.ru/omnitus

OMNITUS

Clinical and pharmacological group

Antitussive drug

Active substance

— butamirate citrate (butamirate)

Release form, composition and packaging

◊ Modified-release tablets, yellow to orange, round, biconvex, film-coated.

1 tab.
butamirate citrate	20 mg

Excipients: lactose monohydrate - 218.5 mg, hypromellose - 70 mg, talc - 10 mg, magnesium stearate - 8 mg, colloidal anhydrous silicon dioxide - 2 mg, povidone - 1.5 mg.

Shell composition: hypromellose - 5.105 mg, talc - 4.7 mg, ethylcellulose - 3.14 mg, macrogol - 1.253 mg, titanium dioxide - 1.041 mg, sunset yellow dye (E110) (11%) - 1.261 mg.

10 pieces. - blisters (1) - cardboard packs.

◊ Modified-release tablets, dark red, round, biconvex, film-coated.

1 tab.
butamirate citrate	50 mg

Excipients: lactose monohydrate - 230.5 mg, hypromellose - 85 mg, talc - 10 mg, magnesium stearate - 12 mg, colloidal anhydrous silicon dioxide - 6 mg, povidone - 1.5 mg.

Shell composition: hypromellose - 5.305 mg, talc - 4.95 mg, ethylcellulose - 3.183 mg, macrogol - 1.273 mg, titanium dioxide - 1.061 mg, crimson dye Ponceau 4R (E124) - 2.122 mg, brown varnish (sunset yellow dye (E110) , azorubine dye (E122), black dye (E151)) - 106 mcg.

10 pieces. - blisters (1) - cardboard packs.

◊ Syrup in the form of a transparent, colorless, viscous liquid with the smell of vanilla.

1 ml
butamirate citrate	800 mcg

Excipients: sorbitol 70% (non-crystallizing) - 405 mg, glycerol - 290 mg, sodium saccharin - 600 mcg, benzoic acid - 1.15 mg, vanillin - 600 mcg, anise oil - 150 mcg, ethanol 96% - 3 mcg, sodium hydroxide - 100 mcg, purified water - up to 1 ml.

200 ml - dark glass bottles (1) complete with a measuring spoon (volume 5 ml, with a line for a volume of 2.5 ml) - cardboard packs.

pharmachologic effect

Antitussive drug of central action. Butamirate citrate is neither chemically nor pharmacologically related to opium alkaloids. Has a direct effect on the cough center. It has an expectorant, moderate bronchodilator and anti-inflammatory effect. Improves spirometry and blood oxygenation.

Pharmacokinetics

Suction

After oral administration, absorption is high. After oral administration of the drug in the form of a syrup at a dose of 150 mg, Cmax in plasma of the main metabolite (2-phenylbutyric acid) is observed after 1.5 hours and is 6.4 mcg/ml, when taking a modified-release tablet (50 mg) it is 9 hours and 1.4 mcg/ml, respectively. ml.

Distribution and metabolism

Butamirate citrate is rapidly hydrolyzed in plasma to 2-phenylbutyric acid and diethylaminoethoxyethanol. Both of these metabolites, which also have an antitussive effect, are significantly bound to plasma proteins, which explains their long-term presence in the plasma. Subsequently, the main metabolite 2-phenylbutyric acid is oxidized to 14C-p-hydroxy-2-phenylbutyric acid. Does not accumulate.

Removal

T1/2 of butamirate when taking the drug in the form of syrup is 6 hours, in the form of tablets - 13 hours. All three metabolites are excreted by the kidneys, with acidic metabolites mainly in the form of glucuronides.

Indications

- dry cough of any etiology (for colds, flu, whooping cough and other conditions);

- to suppress cough in the preoperative and postoperative period, during surgical interventions, bronchoscopy.

Contraindications

• - lactation period;
• - hypersensitivity to the components of the drug.
• For tablets:
• - pregnancy;
• - children under 6 years of age (20 mg tablets);
• - children and adolescents up to 18 years of age (50 mg tablets).
• For the syrup:
• — I trimester of pregnancy;
• - children under 3 years of age.

Dosage

The drug is prescribed orally.

Tablets 20 mg

Adults are prescribed 2 tablets. 2-3 times/day; children over 12 years old - 1 tablet. 3 times/day; children aged 6 to 12 years - 1 tablet. 2 times/day.

Tablets 50 mg

Adults are prescribed 1 tablet. every 8-12 hours

1. The tablets are taken before meals without chewing.
2. Syrup
3. Adults are prescribed 6 measuring spoons (30 ml) 3 times a day; children over 9 years old (body weight over 40 kg) - 3 scoops (15 ml) 4 times a day; children aged 6 to 9 years (body weight 22-30 kg) - 3 scoops (15 ml) 3 times a day; children aged 3 to 6 years (body weight 15-22 kg) - 2 scoops (10 ml) 3 times a day.

From the digestive system: nausea, diarrhea.

Other: exanthema, dizziness, allergic reactions.

Overdose

Symptoms: nausea, vomiting, drowsiness, diarrhea, dizziness, decreased blood pressure.

Treatment: orally - activated carbon, saline laxatives, if necessary - symptomatic therapy.

Drug interactions

Drug interactions with butamirate have not been described.

special instructions

During the treatment period, it is not recommended to prescribe drugs that depress the central nervous system (including sleeping pills, antipsychotics, tranquilizers), patients should not drink alcohol.

Patients with diabetes mellitus can be prescribed the drug, because Sorbitol and saccharin are used as sweeteners in the syrup; the tablets contain lactose.

1 ml of syrup contains 0.003 ml of ethanol. When taking the recommended single dose, the patient receives 0.03 ml of ethanol in 10 ml of syrup. It should be borne in mind that this poses a danger for patients with liver disease, alcoholism, epilepsy, brain diseases, as well as for pregnant women and children.

Pregnancy and lactation

The use of the drug in the form of tablets is contraindicated during pregnancy, and in the form of syrup - in the first trimester of pregnancy.

If it is necessary to use the drug during lactation, the issue of stopping breastfeeding should be decided.

Use in childhood

Contraindication : children under 6 years of age (20 mg tablets); children and adolescents up to 18 years of age (50 mg tablets), for syrup - children up to 3 years of age.

Conditions for dispensing from pharmacies

The drug is approved for use as a means of OTC.

Storage conditions and periods

The drug in tablet form should be stored in a dry place, protected from light, at a temperature of 15° to 25°C. Shelf life: 2 years.

The drug in the form of syrup should be stored in a place protected from light at a temperature of 15° to 25°C. Shelf life: 5 years.

The drug should be stored out of the reach of children.

The description of the drug OMNITUS is based on the officially approved instructions for use and approved by the manufacturer.

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Source: https://health.mail.ru/drug/omnitus_1/

Omnitus

Omnitus is an antitussive agent with expectorant, anti-inflammatory and moderate bronchodilator properties.

Release form and composition

• film-coated tablets, modified release: round, biconvex; 20 mg – from yellow to orange, 50 mg – dark red (10 pieces in blisters, 1 blister in a cardboard pack);
• syrup: viscous colorless transparent liquid with vanilla aroma (200 ml in dark glass bottles, sealed with plastic caps with tamper evident, in a cardboard package 1 bottle with a 5 ml measuring spoon and a 2.5 ml line for measuring volume).

Pills

Composition of 1 tablet:

• active substance: butamirate citrate – 20 or 50 mg;
• auxiliary components (their content for tablets 20/50 mg): lactose monohydrate (218.5/230.5 mg), hypromellose (70/85 mg), talc (10/10 mg), colloidal anhydrous silicon dioxide (2/6 mg), magnesium stearate (8/12 mg), povidone (1.5/1.5 mg);
• film coating composition (for tablets 20/50 mg): talc (4.7/4.95 mg), macrogol (1.253/1.273 mg), ethylcellulose (3.14/3.183 mg), hypromellose (5.105/5.305 mg), titanium dioxide (1.041/1.061 mg); in tablets 20 mg – dye “Sunset” yellow (E 110) (11%) (1.261 mg), in tablets 50 mg – crimson dye “Ponso” 4R (E 124) (2.122 mg) and brown varnish [dye black ( E151), azorubine dye (E122), sunset yellow dye (E110)] (0.106 mg).

Syrup

Composition of 1 ml syrup:

• active substance: butamirate citrate – 0.8 mg;
• auxiliary components: sodium hydroxide (0.1 mg), benzoic acid (1.15 mg), glycerol (290 mg), sodium saccharinate (0.6 mg), sorbitol 70% non-crystallizing (405 mg), ethanol 96% (0.003 ml), anise oil (0.15 mg), vanillin (0.6 mg), purified water (up to 1 ml).

Pharmacological properties

Pharmacodynamics

Butamirate citrate, the active ingredient in Omnitus, has a direct effect on the cough center, improves spirometry and blood oxygenation.

The substance is not related to opium alkaloids either pharmacologically or chemically.

Pharmacokinetics

Butamirate citrate is characterized by high absorption. After taking a tablet at a dose of 50 mg, the maximum concentration (Cmax) in the plasma of the main metabolite is observed after 9 hours and is 1.4 μg/ml; after taking syrup at a dose of 150 mg, Cmax is observed after 1.5 hours and is 6.4 μg/ml. ml. Does not have a cumulative effect.

Butamirate citrate is rapidly hydrolyzed in plasma to diethylaminoethoxyethanol and 2-phenylbutyric acid. Both metabolites also have antitussive effects.

They are characterized by high binding to plasma proteins, due to which they remain in the plasma for a long time. 2-phenylbutyric acid, the main metabolite, is further oxidized to 14C-p-hydroxy-2-phenylbutyric acid.

All these metabolites are excreted through the kidneys. Acidic metabolites are associated mainly with glucuronic acid.

Indications for use

According to the instructions, Omnitus is intended for the treatment of dry cough of any etiology (including whooping cough, influenza and colds).

The drug is also prescribed to suppress cough during bronchoscopy, surgical interventions, and in the pre- and postoperative period.

Contraindications

• lactation period;
• hypersensitivity to the components of the drug.

Additional contraindications for tablets:

• pregnancy;
• children's age: for a dosage of 20 mg - up to 6 years, for a dosage of 50 mg - up to 18 years;

Additional contraindications for syrup:

• I trimester of pregnancy;
• children under 3 years of age.

Instructions for use of Omnitus: method and dosage

Both dosage forms of Omnitus are intended for oral use.

Pills

It is recommended to take Omnitus tablets before meals, swallowing them whole.

At a dosage of 50 mg tablets are prescribed for adults - 1 piece. every 8–12 hours

At a dosage of 20 mg tablets are prescribed as follows:

• adults - 2 pcs. 2-3 times a day;
• teenagers over 12 years old – 1 pc. 3 times a day;
• children 6–12 years old – 1 pc. 2 times a day.

Syrup

Syrup dosages depending on age:

• adults – 30 ml 3 times a day;
• children over 9 years old (body weight 40 kg) – 15 ml 4 times a day;
• children 6–9 years old (22–30 mg) – 15 ml 3 times a day;
• children 3–6 years old (15–22 kg) – 10 ml 3 times a day.

1 full scoop corresponds to 4 mg of butamirate (volume 5 ml of syrup).

Side effects

Omnitus can cause allergic reactions, dizziness, nausea, diarrhea, exanthema.

Overdose

In case of an overdose of the drug, the following symptoms occur: decreased blood pressure, dizziness, drowsiness, nausea, diarrhea, vomiting.

First of all, the use of activated carbon and saline laxatives is indicated. Further treatment is symptomatic (according to indications).

special instructions

Diabetes mellitus is not a contraindication to the use of Omnitus. The syrup contains saccharin and sorbitol as a sweetener. The tablets contain lactose.

In the form of syrup, Omnitus contains ethanol: 1 ml - 0.003 ml. A single dose (10 ml of syrup) contains 0.03 ml.

Due to the ethanol in its composition, the syrup is dangerous for pregnant women, children, patients with brain and liver diseases, epilepsy and alcoholism.

Impact on the ability to drive vehicles and complex mechanisms

Information is absent.

Use during pregnancy and lactation

In the form of syrup, Omnitus is contraindicated throughout the entire period of pregnancy, in the form of tablets - in the first trimester.

If it is advisable to take the drug during lactation, it is recommended to temporarily stop breastfeeding.

Use in childhood

Age restrictions for different forms of release of Omnitus:

• up to 3 years – for syrup;
• up to 6 years – for tablets 20 mg;
• up to 18 years – for 50 mg tablets.

For liver dysfunction

Omnitus syrup contains ethanol, which is why this dosage form of the drug poses a potential danger to patients with liver diseases.

Drug interactions

During treatment, you must refrain from drinking alcoholic beverages. You should not take drugs that depress the central nervous system, such as tranquilizers, antipsychotics and sleeping pills.

Interactions of butamirate with other drugs have not been described.

Analogs

Analogues of Omnitus are Codelac Neo, Sinekod, Panatus, Panatus Forte.

Terms and conditions of storage

Shelf life of different dosage forms:

• tablets – 2 years;
• syrup – 5 years.

Storage conditions: dry (for tablets), protected from light and out of reach of children with an ambient temperature of 15 to 25 ° C.

Conditions for dispensing from pharmacies

Available without a prescription.

Reviews about Omnitus

• According to reviews, Omnitus is an effective, fast-acting and inexpensive drug that eliminates dry cough of various etiologies.
• In syrup form, the product has a pleasant taste and is convenient to give to children.
• The disadvantages of some patients include the high content of dyes in Omnitus tablets, which, in their opinion, are very harmful (it is not clear why they are needed).

Price for Omnitus in pharmacies

The price for Omnitus is:

• 125–220 rubles per pack of 10 tablets with a dosage of 20 mg;
• 170–260 rubles per pack of 10 tablets with a dosage of 50 mg;
• 145–190 rubles for 1 bottle of syrup.

Source: https://www.neboleem.net/omnitus.php