The human papillomavirus (common abbreviation HPV) invades the structure of the skin and mucous tissues. If the immune system is severely weakened and the natural defense mechanism is disrupted, the infection changes the DNA of cells and participates in the process of their direct division.
The main symptom of the disease is dysplasia. The condition is characterized by the appearance of various neoplasms - warts or condylomas. HPV group A9 carries the threat of high carcinogenicity (abbreviation VKR).
Its detection in the body indicates the possibility of developing malignant tumors and oncology.
HPV A9 is a carcinogenic type of papillomavirus
HPV group a9: what is it
Human papillomavirus A9 is a special group that includes precisely those genomes that are characterized by a high risk of oncogenicity. It is highly contagious, and the percentage of infected people is steadily increasing every year.
HPV penetrates the mucous membrane and skin through microdamages and erosions. The most common way of infection is unprotected sexual intercourse and uncontrolled use of personal hygiene items.
It can be passed from mother to child at birth. No genetic dependence has been identified.
Important! Vaccination is the only way to protect against highly oncogenic human papillomavirus with a 100% reliability level.
Only vaccination can prevent infection with papillomavirus
HPV A9 – what is it? The virus of this group includes 20 types, each of which has a marginal cancer risk. It causes damage to the genitourinary system of men and women. Genotyping is carried out using smears and samples of infected tissue. The basis of treatment is the removal of external manifestations of the disease, constant monitoring of relapses, and regular preventive measures.
The classification of papillomavirus is carried out according to the degree of danger of oncological diseases. Among the numerous viruses, doctors distinguish the HPV A7 group.
What is this? Representatives of this genotype cause a precancerous condition.
In this case, it is not at all necessary that the patient be diagnosed with papillomatosis; a single neoplasm on the surface of the body or inside it is sufficient.
Even a single growth on the skin is dangerous
The virus primarily lives in integumentary tissues. For any external manifestation to begin, its concentration must reach its limit. Immunity acts as the main barrier to cell damage.
If the protection is weakened, the risk of infection is higher.
Among the main provoking factors are poor nutrition, chronic stress and fatigue, vitamin deficiency, insufficient physical activity, and promiscuity.
Main symptoms
The main symptom of infection with HPV groups A7 and A9 is dysplasia. This is a condition in which a pathological change in the structure of human tissues or organs occurs.
One example is the appearance of specific growths on the surface of the penis, labia, vagina, uterus, vestibule of the bladder, and rectum.
It is important to realize that formations located inside the body can only be seen by a doctor. Their structure, shape, quantity and color are different.
The virus causes the appearance of papillomas on the genitals
The incubation period, during which cells are degenerated, changing the DNA from HPV A9, stretches for many years. In most cases, a person’s well-being remains normal.
That is why you should contact a gynecologist or urologist for any, even the most minimal, discomfort in the intimate area.
Urgently – in case of bleeding, discharge, cycle changes, pain, unpleasant odor.
For early detection of HPV symptoms, women are recommended to undergo preventive examinations. Their order is assigned once every 4-5 years, less often with age. It is also useful for men to learn about the presence of infection in the body, especially if they are prone to tumor processes. Papillomavirus analysis is a mandatory component of pregnancy screening.
Important! Colposcopy is a penetrating instrumental research method that allows you to detect changes in the vagina and cervix. It is used to take tissue samples for biopsy.
Papillomas can be detected during colposcopy
How does infection occur?
Papillomaviruses are quite unstable in the external environment. However, with close bodily contact, they quickly move into a new microflora and easily adapt to it.
The virus penetrates the cell nucleus of the integumentary tissue and subsequently changes the division process. Under favorable conditions, it is integrated into DNA, and reproduction occurs with the affected structure.
As a result, the infection completely takes over the human body.
Danger of A9 virus
HPV causes many diseases. Cancer is considered the most severe. Due to frequent relapses, the disease must be treated throughout life. It is not possible for any doctor to predict its outcome and consequences.
Only a doctor can assess the degree of danger of a neoplasm
There are known cases of self-healing, in which all symptoms are eliminated without special therapy and never appear again. For a positive prognosis, the pathological process must be detected initially, when symptoms are mild or completely absent.
Diagnosis of the disease
In order to detect the HCR papillomavirus in the body, the same methods are used as for low-degree carcinogenicity (NKR). The result of the quantitative analysis gives an idea of the viral load for HPV. The norm is less than 105 (relatively 3 Lg units). If the indicator is higher, the level of cancer threat increases proportionally.
The patient is referred for a blood test to detect HPV
Important! The dynamics of the concentration of affected cells must be monitored for 3-9 months after drug therapy or surgery.
What modern methods of diagnosing HPV are used:
- Detection of antibodies to the virus. The earliest procedure to capture the process of nascent infection control. Blood is taken for testing.
- Digen test. Gives accurate information about the presence and types of HPV. Biological material is scraping from an area suspected of pathogen activity.
- PCR. The polymerase chain reaction technique is used to determine the genome and the degree of its oncogenicity.
PCR allows you to determine the degree of oncogenicity of the HPV virus
Compliance with the technology and rules for collecting biopsy samples is of great importance for obtaining reliable data. Biological material must be clean, in sufficient volume, and suitable for its shelf life.
What the results say
All diagnostic measures are painless, non-hazardous, and low-traumatic. They do not require special preparation to carry out, and the result is delivered quickly enough. The values of the indicators are deciphered by a specialist - gynecologist, urologist, dermatologist, oncologist.
Important! The PCR method determines the number of cells infected with the HPV virus present in the tests, which is different from the norm.
The results of the analysis must be deciphered by a doctor
The results of PCR diagnostics can be as follows:
- Not detected. HPV is not in the body.
- Up to 3 Lg. The virus exists, but its numbers are insignificantly small.
- From 3 to 5 Lg. The infection develops and treatment is necessary.
- Over 5 Lg. The concentration of infected cells is high, there is a threat of cancer.
The highly accurate Digen test allows for HPV typing. Its data reflects the number of copies of the virus by type. The value of the acceptable threshold is equal to 100 thousand DNA copies in 1 ml of biomaterial, conventionally – 1 relative unit. Thus, according to these criteria, A9 (16) – 1 is sufficient for the development of cancer.
Digen test is the most accurate way to genotype the HPV virus
Treatment with medications
Tactics to combat the virus are selected by the doctor exclusively on a personal basis, based on the condition, external manifestations, test results and research. Group A9, A7, different from the norm, requires immediate treatment.
Important! Interferon drugs are used to protect and treat HPV. They contain special proteins that are similar in structure and function to antibodies produced by the human immune system.
With increased dynamics of the virus in the body, immunomodulators are used to enhance the natural defense against the invasion of infection. In advanced cases, they resort to special treatment. It includes mandatory destruction of tumors, antiviral agents, and potent hormonal drugs.
The patient is prescribed immunomodulators
What to do to avoid getting infected
The risk of infection is always and everywhere present. These are public places, beaches, baths, saunas, swimming pools. There is a high probability of acquiring an infection if you frequently change sexual partners and neglect personal protective equipment. If the mother is a carrier of HPV, then during childbirth it is transmitted to the newborn child.
What you need to do for prevention:
- Visit a specialist in women’s or men’s diseases – a gynecologist or urologist – annually.
- Give up bad habits, lead an active lifestyle, eat healthy and high-quality food.
- Completely cure any other viral, bacterial or fungal infections.
- Maintain your immune system in every possible way and avoid factors that weaken it.
To prevent infection with the virus, you should give up bad habits
The patient must understand that detection of HPV is not a disease. This indicates a more attentive attitude towards health and well-being. If viruses with a high oncogenic risk are identified, this is followed by a thorough step-by-step examination and systematic monitoring of the dynamics of indicators.
Each analysis is necessary to confirm, clarify, supplement the diagnosis, and formulate an effective treatment plan. A positive prognosis is typical for the early stage, when the development of infection can still be prevented.
The doctor will tell you more about dangerous types of HPV in the video:
Source: http://bolezni.com/stati-o-boleznyah/papilloma/vpch-a9.html
Tablets for papillomas and HPV
Papilloma is a benign tumor-like formation of a viral nature. The formation of a pathological growth on the epidermis provokes an obvious cosmetic defect, on internal organs it can cause bleeding and ulcers, and in the larynx it impairs the voice and respiratory function. Despite successful treatment, there is a risk of relapse with complications, namely degeneration into a malignant formation. Treatment of papillomavirus is carried out comprehensively; in addition to taking pills, laser removal of tumors is carried out.
Diagnostic features
Human papillomavirus infection unites a group of pathologies, the development of which is caused by the action of HPV. This microorganism can cause serious health problems. It affects the skin, mucous membranes, and can be transmitted sexually and through skin contact. The following manifestations of the virus are mainly recorded:
Diagnosis of the disease is carried out by a dermatologist, venereologist. Given the large variety of the virus, it is extremely difficult to make a reliable diagnosis as a result of a visual examination. This is possible in the case of genital warts, but there is no information about the oncogenicity, the type of the virus itself. If there is a suspicion of HPV, it is important to carry out PCR diagnostics of the DNA of the virus.
When the main method of therapy remains removal of the papilloma, then in parallel it is necessary to perform a biopsy for cytological examination. This will allow you to get the most accurate result regarding malignancy and the degree of changes in the human body.
Effective ways to fight the virus
In each case, the treatment regimen is selected strictly individually. When the human papillomavirus is detected during the diagnostic process, but there are still no symptoms, preventive treatment with cytostatics is carried out.
With its help, you can easily “put to sleep” HPV for several years.
Persons who are carriers of the virus are required to regularly carry out PCR diagnostics and use only proven means of contraception - condoms, so as not to infect their sexual partner.
If the virus manifests itself on the skin or mucous membrane, it is recommended to resort to the following methods:
- laser removal;
- cryodestruction;
- surgical excision;
- electrocoagulation;
- radio wave method.
Removing papillomas does not guarantee getting rid of the appearance of new formations. That is why patients are recommended to undergo periodic examinations and also undergo a course of antiviral treatment.
HPV is often transmitted sexually, so you should protect your partner by using a condom.
If you are planning a pregnancy, it is necessary to carry out diagnosis and treatment to reduce the risk of infection of the child during childbirth.
Types of medications for HPV
Treatment of the virus should be combined, carried out in several directions simultaneously. For this purpose it is common to use the following medications:
- Immunomodulators. Designed to strengthen and enhance the human immune system in order to actively fight the virus.
- Antiviral agents. Helps reduce the intensity of the influence of HPV on the patient.
- Creams, ointments. Helps remove growths.
In most cases, papillomas disappear on their own - after high-quality complex therapy.
Features of prescribing medications
- Isoprinosine. This is a powerful immunostimulating agent with a pronounced antiviral effect. The tablets must be taken after meals and follow the instructions, as there are a number of contraindications. Isoprinosine helps to activate protective functions, enhance the production of leukocytes and immunoglobulins, which ensures the destruction of the virus. Each tablet contains 500 mg of the active substance, namely inosine pranobex. Children over 12 years of age and adults are prescribed 1-2 tablets four times a day, washed down with plenty of water. The duration of the treatment course is from two weeks to a month, then a thirty-day break is taken. The treatment is repeated twice. There is a risk of developing a side effect - deterioration of the gastrointestinal tract.
- Groprinosin. This is one of the best analogues of the previous product; it contains a substance such as inosine. It has an antiviral and immunomodulatory effect. The daily dose is eight tablets, the duration of therapy can vary from one to two weeks. In some cases, Groprinosin is taken for six months, taking breaks. It all depends on the frequency of relapses and the severity of the condition. It has a milder effect than Isoprinosine, so they are prescribed to elderly people with angina pectoris.
- Acyclovir. The release form of the drug is cream, ointment, tablets. It is a synthetic analogue of purine base. An immunostimulating effect is observed, helping to block the production of viral DNA, which prevents the proliferation of pathogenic microorganisms. Children over two years old are allowed. Usage pattern: 5 times per knock. If the form of the pathology is too severe, then the single dosage is increased to two tablets. Contraindications include allergies to the composition and the period of breastfeeding. Drink with extreme caution during pregnancy, as well as in case of kidney failure.
- Lycopid. It has a strong immunostimulating effect on the human body. Provides fight against HPV, pathogenic microorganisms and fungi. Likopid helps enhance the medicinal effect of all other drugs. The main advantage is that it has no contraindications, therefore it is approved for the treatment of children. Dosage – one tablet three times a day for two weeks. After the course, you need a ten-day break, and then take it again.
- Allokin-Alpha. The drug has a complex effect: immunostimulating and antiviral. It is produced in the form of a powder in ampoules, on its basis an injection solution is prepared. The patient is given at least six injections every other day. The drug is administered in a dosage of 1 milligram at a time. Allokin-Alpha significantly reduces the risk of recurrence of the disease. Suitable for men and women, but the best results are recorded at the early stage of the disease. If we are talking about new growths, then they are easy to get rid of even without surgical intervention. Contraindications for use: pregnancy, childhood.
- Immunomax. The herbal drug is very effective in the fight against HPV. Helps stimulate and activate antiviral immunity. Release form: powder for injection. It is mainly prescribed after surgical removal of papilloma to prevent relapse. An intramuscular injection is given on the first, second and third days, the course is repeated on the eighth, ninth, tenth day.
- Wobenzym. Copes well with inflamed papillomas. Relieves swelling, eliminates burning and itching of the affected part of the skin. The drug is complex, the main properties are: decongestant, anti-inflammatory, secondary analgesic, immunomodulatory, fibrinolytic. At the beginning of therapy, take 5-10 tablets three times a day, then reduce the dosage to 3-5 pieces half an hour before meals. Contraindications: likelihood of bleeding, personal intolerance. Can be taken during lactation and pregnancy.
- Polyoxidonium. It has several forms of release: powder, suppositories, tablets. As for the powder, it is used to prepare a solution for injection. The use of suppositories can be rectal or vaginal. The course of therapy is twenty suppositories, one each for the first three days, then every other day. Excellent tolerability and effectiveness are noted.
- Verrucacid. This is an excellent choice for those who prefer to treat papillomas with drops. The kit includes a convenient applicator that ensures precise application to the papilloma. The drug is considered new, so it contains many relevant, effective developments. Apply directly onto the affected part of the skin - three times a day. The composition contains the active substance – metacresol. An effective effect on the tumor-like growth is observed; it is possible not only to cauterize, but also to destroy the viral infection.
- Condilin. Unique drops with herbal composition. The main method of influence: cauterization, drying, as well as an antitumor effect. Apply to papilloma morning and evening for four days. After this, you need a break for five days and repeat the course. The total duration of therapy should not exceed five weeks. It is important to know that the effect of the proposed drug can be called aggressive, so you should use it carefully and in limited quantities. Avoid contact with healthy epidermis.
- Feresol. The drug occupies a leading position among all drugs intended to combat papillomas, moles, condylomas, and warts. Oily liquid has many positive reviews. The product is applied to the affected area, do not touch healthy skin. Carry out continuous lubrication for ten to forty-five minutes, it all depends on the size of the tumor formation. The approximate number of manipulations is 5.
- Keravort. The cream contains 5% synthetic immunomodulator imiquimod. Suitable for complex treatment of neoplasms. Apply to the skin three times a week before bedtime, rinse with warm water in the morning. It is not advisable to use it during pregnancy, with the exception of multiple formation of papillomas. Sold by prescription. Despite its high effectiveness, sometimes side effects such as pain, itching, and burning in the area of application occur.
Lapis pencil for papillomas and warts
In addition to the medications listed, many patients use alternative home remedies: super celandine, iodine, hydrogen peroxide and lapis pencil.
The choice of drug directly depends on the degree of damage, the size of the tumor and the area of localization, and oncogenicity. In any case, there is no need to experiment and risk your own health and life. If there is a suspicion of human papillomavirus, it is important to immediately visit a dermatologist or venereologist.
Undergo a full diagnosis, begin timely and competent treatment, taking into account all contraindications and exceptions. Considering that there is no one hundred percent chance of a complete cure, it is important to constantly be examined and tested.
As for medications, immunomodulators and antivirals remain the most effective and relevant.
Video on the topic:
Source: https://papillomus.ru/preparaty/tabletki-ot-papillom-i-vpch/
HPV group a9: what is it and what are the characteristics of the infection
HPV type A9 is a type of virus that carries a risk of carcinogenicity. When advanced, the disease can lead to the development of malignant tumors in various parts of the body. In men and women, the external manifestation of the virus is different, but most often it is localized in intimate places. This group of strains has its own characteristics that require complex treatment.
Content
Danger of group A9 virus
All HPV viruses are divided into several groups:
- not oncological;
- low level of oncogenicity;
- average;
- high level of oncology.
Groups allow doctors to better determine the extent of the disease and prescribe correct and effective treatment.
Additionally, the phylogenetic classification is known:
- papillomavirus A9;
- HPV A7;
- A5-A6 groups.
It is papillomavirus A9 that can cause a tumor of the head of the penis in men, but such cases are extremely rarely recorded, since the symptoms practically do not appear.
In women, the HPV strain causes flat-type condylomas on the vaginal tissues and on the cervix, and also, cells can change and tissues can be damaged. After erosion, dysplasia tends to develop, and the final stage of this disease is already the initial stage of cancer.
For HPV group A 9 to begin to change the mucous membranes of the uterus, more than 20 years may pass from the moment of infection, but it is better to identify the disease at an early stage of development in order to cure it without much difficulty or risk.
Where does the infection come from?
But since strains of the papilloma virus belong to the oncogenic group, the infection is mainly transmitted sexually, and it is almost impossible to become infected with it in everyday life, except through the use of personal hygiene items. These could be towels, razors, etc.
How to prevent infection
To prevent A9, every person must undergo a course of treatment, but vaccination is even better. It is carried out between the ages of 9 and 25 years. As for women, they must undergo this injection to reduce the risk of cervical cancer.
We recommend reading:
- HPV screening
- HPV type 35 in women
- Oncogenic HPV type
For this procedure, two modern and innovative vaccines are used:
Gardasil is broader in protection; it also prevents the manifestation of genital warts. Cervarix is less effective, but can also prevent infection.
Like all vaccines, Cevrarix and Gardasil contain empty shells of the pathogen, and when they enter the human body, they activate the production of white blood cells. This will lead to the fact that the body, after infection with HPV, will produce antibodies itself, and will gain greater immunity to the virus.
What you need to do to avoid getting infected with HPV:
- Always use protection during sex, although doctors say that condoms do not help.
- Maintain immunity, prevent hypothermia, overheating and stress.
- Try not to take immunosuppressants, which reduce the system's defenses.
Strong immunity is the basis for prevention against HPV. It is worth consuming enough different groups of vitamins all year round and maintaining good physical shape. Don’t forget about proper and balanced nutrition, and when you follow all the rules, your body will be able to cope with the virus on its own.
Diagnostic measures
When examined by a gynecologist, the doctor can easily identify genital warts and papillomas. Flat-shaped growths on the mucous membrane of the vagina and cervix are not so easy to see, because their color is slightly different from healthy cells.
Cutaneous neoplasms of a flat structure, which are caused by strains 16, 31, 35, are lubricated with 3% vinegar acid, after which the papilloma turns white.
In some cases, colposcopy is performed - this is a microscopic examination to take tissue for analysis from the mucous membranes of both the vagina and cervix. Strains 16 and 31 are very easy to detect thanks to the PCR method (polymerase chain reaction). The doctor diagnoses the virus and performs genotyping. This method does not allow determining the number of infection particles.
Given that information about the viral load gives doctors the opportunity to prescribe the right treatment for a patient, HPV types 16 and 31 are being diagnosed thanks to more innovative research. For this purpose, a special Digen test is used. Using the method, it is possible to determine the presence of infection in the body and the genotype. It is carried out by taking a smear from the genital mucosa.
For additional results, a biopsy is done - taking a tissue sample from the infected area. This method makes it possible to study the histology of papilloma and determine all kinds of abnormalities.
What is destruction and what is it for?
Destruction is a method of removing papillomas by destroying them from cells.
Considering that some strains of the virus cause malignant tumors, mandatory removal of condylomas is necessary. The following methods are used for this process:
- removal by laser exposure;
- removal of warts using radio wave therapy;
- universal method of electroextension.
Growths that appear as a result of parasitism by types 31, 35, 33 of the virus are destroyed using radio wave surgery. This method is no less effective than laser, due to the fact that the healing of the removal sites is quite fast. The radio wave device does not leave visible traces of removal.
One frequently used method is electrocoagulation. Unlike the two previous removal methods, it does not burn papillomas by exposure to high temperatures, but cuts off the formations. The big disadvantage of this method is the long healing time.
Drug treatments
After the destructive method, therapy is required to increase immunity and reduce the concentration of human HPV A9 in DNA. This is done by taking various medications. After taking medications, the A9 group of viruses slows down the spread and development; in addition, it loses the ability to reproduce, which significantly reduces the possibility of relapse.
Doctors try to simultaneously prescribe both appropriate medications to block the virus and vitamins to improve the immune system in order to achieve maximum results in treating the disease.
In order to reduce the concentration of infection in the blood, Panavir is often prescribed, which is in the form of a solution or injection, and to strengthen the immune system, interferon inducers (suppositories, creams and ointments) are prescribed. The technique allows you to increase resistance to the effects of the virus.
It should be noted that there are drugs in the form of pills, for example, “Groprinosin”. This medication stops the development of strains 31 and 58.
To prevent relapse of the virus, experts prescribe Aldar-cream. For the same reason, some doctors prescribe Zovirax. The product is used to treat herpes, but doctors believe that it fights well against types 31 and 52 of the virus.
With proper treatment, a person will be able to completely get rid of the manifestations of papillomavirus and strengthen the immune system to avoid recurrence.
The article has been verified by the editors
Source: https://CoriumMed.ru/papillomy/tipy/vpch-a9.html
HPV group a9: causes, symptoms and comprehensive treatment
Group a9 refers to highly oncogenic species, the manifestations of which affect the genitourinary and anal areas. Extensive DNA research on HPV a9 is currently being conducted. It is important to diagnose the type in time, begin its comprehensive treatment and remove growths in a timely manner.
Features, what is it and danger
HPV group a9 includes potentially oncogenic types. They can provoke the development of cervical and bladder cancer in male patients.
Other oncological and non-oncological processes associated with HPV:
- warts, including genital warts;
- papillomas;
- genital warts;
- cervical dysplasia;
- intraepithelial neoplasia of the vulva, vagina;
- leukoplakia.
HPV infection occurs through close contact with someone who has the virus. Epithelial cells of the skin and mucous membranes undergo proliferation. HPV is transmitted through sexual contact - classic genital, anal, oral.
The risk of infection is about 60% with a single act, which indicates a fairly high contagiousness of the virus. HPV is not selective and affects approximately equal numbers of men and women.
Vertical transmission from mother to fetus during natural delivery of pregnancy cannot be excluded.
Flow:
- latent: the virus persists without clinical manifestations with colposcopic, cyto-histological norms;
- productive phase: signs of infection (growths) are present. The virus multiplies rapidly, the presence of the pathogen is confirmed by PCR;
- neoplasia: HPV a9 DNA inserts into the cell genome. Infection is proven histologically; signs of damage to the cervical epithelium are revealed during colposcopy;
- With carcinoma, there is cell atypia, indicating the malignancy of the process.
Which strains are included in group a9
This group includes strains 16, 18, 31, 33, 35, 52, 58, 67. Responsible for the formation of genital warts and papillomas in the urogenital areas - 16, 18, 31, 33, 35. 16 and 18 are recognized as the most carcinogenic. accounts for up to 70% of all episodes of infection. Genotype 18 is often detected in adenocarcinomas.
52, 67, 58 are oncogenic strains with high potential. Patients are subject to formidable changes: they are diagnosed with malignant pathology of the cervix and mammary glands. In men, it causes damage to the penis and bladder.
The process of malignancy is not fast and takes up to 15 years from the appearance of the virus in the body to the development of serious manifestations. During this period, the appearance of genital warts is recorded, then erosion, which without treatment leads to dysplasia and neoplasia - the development of cancer.
Symptoms of the virus and diagnosis
Often, an HPV infection present in the body never makes its debut, remaining asymptomatic. The subclinical form is revealed only histologically or during colposcopy and is represented by small flat warts.
The manifestation of the genital form is manifested by the appearance of genital warts, which are found in areas of increased maceration - the labia, anus, and clitoris. The external opening of the urethra in women is affected in a small percentage of episodes; further changes in the urethra give symptoms of chronic urethritis.
Genital warts do not show active symptoms; a gynecologist diagnoses them by chance during an examination or by conducting a Pap test.
The onset of the disease is usually missed by the patient due to the absence of signs. Itching, a specific smell and even pain are caused by large, secondary infected growths that are injured during sexual intercourse.
In men, they cause a bifurcation of the urinary stream, even an obstructive orifice defect.
Genital formations affect the genitals, and with oral contact, the lips and oral cavity. Warts near the anus are more common in homosexuals.
HPV strains 16 and 18 provoke:
- cervical intraepithelial neoplasia;
- RSM;
- bowenoid papulosis;
- cancer of the anus, vulva (not common).
Bowenoid papulosis with non-raising papules occurs in men who are promiscuous, in whose sexual partners HPV infection causes changes in the cervix and accompanies cervical intraepithelial neoplasia (cervical cancer).
Treatment methods for papillomavirus a9
When treating HPV a9, an individual approach is important, taking into account drug tolerance and the patient’s allergic status. The presence of HPV indicates reduced immunity; immunomodulatory agents must be included to prevent relapse and prevent the appearance of malignant tumors.
Antiviral therapy
The plant polysaccharide Panavir is administered intravenously in an amount of 5 ml (total dose of 5 injections) with a break of 2 days.
The gel is indicated as a therapeutic monotherapy for papillomatosis after destruction to prevent relapse. Course - up to 21 days, 2-3 times a day.
To combat vaginal and rectal growths, suppositories containing potato shoot extract are produced, which can be purchased at the pharmacy with a prescription.
Riodoxol and bonaftone ointments applied to the lesion fragment are used up to 6 times a day for up to 21 days.
Antitumor agents
Indinol-3-carbinol, or simply Indinol, selectively suppresses gene expression and causes the death of cells with HPV. The course is 400 mg daily for three months.
Immunotherapy
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The use of interferons is complex and variable. Human leukocyte interferon is applied as an application for 2 weeks to the pathological site.
Injections are made intracondyloma or subpapilloma (1 million IU - daily dose) three times a week for three weeks.
Suppositories “Reaferon”, “Viferon” are inserted 3 times every 7 days for 21 days in order to eliminate external growths and increase local tissue immunity. Interferon ointment - applied three times a day.
Action of Groprinosin in tablets:
- blocking the replication of virus particles by damaging the genetic apparatus;
- increased activity of macrophages;
- multiplication of the number of lymphocytes;
- formation of cytokines.
Adaptogens
In the complex, herbal products are prescribed: Schisandra chinensis extract, Eleutherococcus, vitamins C, B, D, E. Sedatives may be prescribed: Persen, valerian, Novopassit to level out the emotional background, relieve anxiety and depression during long-term treatment.
Vaccination
Gardasil is a drug against human papillomavirus (types 6, 11, 16, 18). Staging a full course leads to the formation of specific antibodies for at least three years in all age groups.
The vaccine is believed to prevent the appearance of malignant neoplasms on the genitals.
Indicated in children and adolescents up to 17 years of age and in women up to 26 years of age in order to prevent HPV-associated pathology.
Review of methods for removing papillomas
| Method | Name of drug/effect | Release form/procedure | Method and scheme of application/procedure algorithm | Contraindications |
| Cytotoxic | Podophyllin, Podophyllinotoxin | Solution Gel |
The area with pathology is treated with mandatory rinsing after 5 hours and a pause of 3-6 days. The course is 5 weeks. | Pregnancy, childhood. |
| Kondilin | Liquid | Application is carried out with an applicator only on the changed area twice a day for three days. |
|
|
| Feresol | Solution | Apply once every ten days until the effect is achieved. |
|
|
| Chemical | Solcoderm | Liquid | It is applied to the abnormal fragment after applying alcohol with a spatula with an interval between sessions of 1-4 weeks. |
|
| Epigen spray | Aerosol | Irrigate formations 6 times a day for a week when installing a vaginal attachment. | Sensitivity to components. | |
| Trichloroacetic acid | Ninety percent solution | Application once every 7 days until visible coagulation necrosis of the formations for a period of approximately 6 weeks. | Can be used during pregnancy. | |
| Physical destruction | Diathermoedecrocoagulation | Cauterization | The pathological mucous membrane is cut off with a loop, the wound is cauterized with a ball electrode. |
|
| Laser therapy | "Evaporation" with laser | Number of sessions until visible results are achieved. |
|
|
| Radiosurgery | Electrical destruction | In electrodissection modes, condylomas, electrocoagulation - warts, flat condylomas, dysplasias are removed until clinical recovery. |
|
|
| Cryodestruction | Freezing | Crystalline ice forms in the cells with tissue necrosis, stimulating an immune response. One application for 11 seconds. The procedure is repeated if necessary after seven days. |
|
|
| Surgical | Excision | Under anesthesia, the formation is incised borderline, capturing the normal mucous membrane. Sutures are placed on the removal area. |
|
Precautions to take if you have a virus in your body
Patients with HPV a9 (16)-1 and other types should be aware that the infection is transmitted sexually, and even the use of a condom cannot protect against infection. The main preventive measure is not to contact sick people, which is hardly feasible in reality. It is recommended not to enter into promiscuous relationships and to have one examined sexual partner.
Rules for virus carriers:
- inform your partner about your illness;
- limit contact for a time due to any therapy;
- examine and treat each partner in parallel with the HPV carrier.
When initially detecting the disease in a pregnant woman, it is necessary to keep in mind the possible infection of the newborn during childbirth. Laryngeal papillomatosis and anogenital warts in newborns are associated with this.
Therapy for HPV infection can suppress the manifestations of papillomavirus by blocking the activity of the pathogen. Surgical methods destroy cells with viruses located in them.
But the risk of relapse under unfavorable circumstances remains high. Patients are forced to regularly see a doctor and undergo diagnostics.
It is unacceptable to use folk recipes or independently decipher titers in tests.
Source: https://VashaDerma.ru/hpv/a9
HPV group a9: features of the disease and degree of danger
Today, science knows more than 100 types of human papillomavirus infections, the danger of which is that they can be asymptomatic, and as a result lead to life-threatening diseases.
Scientists include HPV group A9, which is localized in the area of the genitourinary system, as a highly oncogenic species.
This includes strains 16, 18, 31, 33, 35, 52, 58, 67, which provoke the development of pathological malignant tumors of the cervix, mammary glands in women, and the bladder and penis in men.
In women, more than 15 years can pass from the moment of infection to visible changes in the epithelial tissue of the vagina and uterus: first, the development of condylomas on the mucous membranes and cervix leads to erosion, if left untreated, to dysplasia, and then proceeds to the initial stage of cancer development. In the early stages, HPV A9 can be eliminated without the risk of relapse. In men, cancer is diagnosed much less frequently; as a rule, they remain carriers of the virus.
Clinical manifestations of strains
The group of papilloma viruses A9 is united by similar pathological symptoms, affected area, and similar DNA structure. Thus, as a result of infection, patients may experience:
- Specific growths of soft consistency over the surface of healthy epithelial and mucous tissues. Strains 22, 52, 58 are characterized by the appearance of growths in the anal area, on the rectal mucosa.
- Stool disorder.
- In women - disruption of the menstrual cycle, bloody or whitish discharge (profuse, with an unpleasant odor).
- Bloody discharge during or after sexual intercourse.
Such symptoms can be confused with manifestations of an STD, so be sure to undergo examination by a gynecologist or urologist. To determine the pathogen strain, the PCR method is used, and for viral load indicators, the Digene test is used.
Features of virus types 16, 18
According to research, cancer is diagnosed most often in carriers of HPV A9 DNA of these types. Papilloma develops in the body in several stages:
- Initial, invisible and asymptomatic, during which a person may not even be aware of the infection.
- The appearance of neoplasms on the genital organs (genital warts); in women, this process can develop into cervical dysplasia.
- Intensive development of growths, their fusion with each other, and in the vagina such formations can become damaged and inflamed.
In the male body, the A9 virus type 16 can remain inactive for decades, sometimes manifesting itself in the form of condylomas, spots, erythema, and plaques.
Less commonly, infection leads to Bowen's disease with the formation of a characteristic red plaque on the penis, which over time becomes rough and overgrown with small scales.
Papillomatosis type 18 is not so common, but at the same time its development is more rapid, requiring not only the removal of tumors, but also a mandatory active increase in general immunity.
Manifestations of genotypes 31, 33, 51, 52, 58
Types 31 and 33 of viruses are also considered highly oncogenic, capable of causing cervical intraepithelial neoplasia in women, and bowenoid papulosis in men. The risk of developing papulosis is increased in men who are prone to frequent changes of sexual partners.
Cervical neoplasia in the primary stages can only be detected by cytological examination of a smear; in advanced stages it is classified as an oncological disease.
Infection with HPV A9 genotypes 51, 52, 58 occurs predominantly through sexual contact and is considered one of the most dangerous in terms of transformation into oncology. In women, it progresses to erosion, cervical dysplasia, pathological neoplasms in the rectum, and anal area.
Type 51 is often diagnosed in men suffering from cancer of the anus and penis.
Treatment methods for papillomavirus
The presence of HPV in the body, first of all, indicates a weakened immune system. Therefore, therapy should include a complex of immunomodulatory agents to resist infection and reduce the risk of relapse and the development of malignant tumors. With the development of precancerous and cancerous formations, chemotherapy and antiviral drugs are prescribed.
If there are growths on the epithelial and mucous membranes, they must be removed by destructive (invasive) methods. Since group A9 virus strains are localized in the genital and anal areas, removal methods are treated with particular care, excluding cryodestruction and using:
- Laser coagulation, in which growths are removed with laser radiation without bleeding or scars. This method is quite effective, for example during pregnancy.
- Removal of papillomas using radio waves is used to excise single small growths. Its advantage is the absence of scars and a short recovery period.
- Electrocoagulation, in which the tumor is removed with an electric current, and the growth disappears, leaving scars.
- With a high risk of degeneration of genotypes 33, 31, 16, surgical removal of growths with a scalpel along with surrounding tissues is used. It is characterized by increased trauma.
After removing the growths, specialists prescribe in parallel a complex of antiviral and immunomodulatory drugs in order not only to block the development of infection, but also to improve the general condition of the body.
Panavir, groprinosin, Zovirax are most often used as antivirals, and interferon inducers are used to enhance immunity.
If you follow the treatment regimen recommended by your doctor, it is possible to completely get rid of HPV manifestations with a reduced likelihood of relapses.
Disease prevention
People who care about their health and want to prevent infection with papillomavirus should take into account that preventive measures can be specific and non-specific.
Vaccinations are specific, in particular, in modern medicine it is proposed to use the vaccines Cervarix and Gardasil, which contain empty shells of viruses, and when they enter the body they provoke the production of leukocytes and antibodies to HPV.
Cervarix is used to vaccinate girls, Gardasil is suitable for both sexes and additionally protects against the formation of papillomas and genital warts. Preventive vaccinations are recommended up to age 25, preferably before sexual activity begins.
Nonspecific methods of prevention include:
- having a permanent, trusted sexual partner;
- in case of casual sexual contact, it is necessary to use high-quality barrier contraception, as well as treat the genitals with antiseptics (miramistin, chlorhexidine) after contact;
- a healthy lifestyle, avoiding alcohol, nicotine, drugs, avoiding stress and emotional distress;
- observing personal hygiene rules, not using other people’s personal belongings;
- timely treatment of any viral, fungal, bacterial infections, especially STDs;
- regular preventive examinations with a gynecologist and urologist.
It is important to remember that HPV group A9 provokes the development of extremely dangerous cancers, so treatment should be started as quickly as possible. Complex therapy is effective in most cases of infection, and preventive measures help prevent relapses of papillomatosis.
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Source: https://opapillome.ru/vidyi-papillom/vpch-a9.html
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