When should fluimucil be used for cough in adults and children?

When treating diseases of the respiratory system, drugs from the group of mucolytics are especially in demand, one of which is Fluimucil. Is it prescribed to children, for what pathologies and in what doses?

Fluimucil is a product of the Italian pharmaceutical company Zambon and is available in several forms:

1. A solution to be taken orally . It is a colorless liquid that smells like raspberries (in smaller dosages) or strawberries and pomegranate (in higher dosages). The liquid is usually clear and may have a faint sulfur odor. This solution is poured into glass bottles of 100, 150 or 200 ml and supplemented with a measuring cap made of translucent plastic.
2. Solution for injection , which is also used for inhalation. It is bottled in ampoules made of dark glass. One box contains 5 ampoules, each containing 3 ml of colorless transparent liquid with a slight sulfuric odor. If an opened ampoule is left exposed to air, the solution may turn pink-violet over time.
3. Granules from which a solution is made, taken orally. They are sold packaged in multi-layer bags, and one pack contains 20, 30 or 60 such portioned bags. The granules themselves are white-yellow in color, smell of orange and a little sulfur, and after stirring in water they produce a yellowish orange drink.
4. Effervescent tablets. They are available in packages of 10-20 pieces, but due to the high dosage, this form of Fluimucil is not prescribed to children.

All versions of Fluimucil contain a substance called acetylcysteine ​​as the main ingredient. Its amount in different preparations is as follows:

• in the finished solution, which is given to children to drink - 20 mg or 40 mg in 1 milliliter;
• in one bag of granules – 100 mg or 200 mg;
• in solution for injections and inhalation use – 100 mg in 1 milliliter (300 mg per ampoule).

Additionally, the Fluimucil solution taken orally contains sodium saccharinate, flavoring, sodium hydroxide, sodium benzoate and some other substances. The granules contain sorbitol, flavoring, betacarotene and aspartame in addition to acetylcysteine. The solution, which is used for injection or inhalation, additionally includes sterile water, disodium edetate and sodium hydroxide.

In terms of its action, Fluimucil is a mucolytic, because its active ingredient affects the mucus formed in the respiratory tract, as a result of which it is removed from the bronchi more actively and the child recovers faster. The sulfhydryl groups present in acetylcysteine ​​help break down the bonds in mucopolysaccharides found in sputum. Due to this interaction, the viscosity of bronchial secretions decreases.

The activity of the drug does not decrease if there is pus in the sputum. The medication also activates the synthesis of glutathione and has antioxidant properties, due to which harmful substances (toxins, free radicals) are more actively removed from the body. In addition, studies have shown that the use of Fluimucil reduces the severity and frequency of exacerbations in cystic fibrosis and chronic bronchitis.

The drug is prescribed for various respiratory diseases in situations where the patient’s sputum is too viscous and this makes it difficult to cough up. "Fluimucil" is in demand for:

• chronic bronchitis;
• lung abscess;
• bronchiolitis;
• bronchial asthma;
• emphysema;
• atelectasis of the lung due to mucus plugs;
• cystic fibrosis (as one of the means of complex treatment).

In addition, the medicine is prescribed after an injury or surgery so that the viscous bronchial secretion is more easily released from the respiratory tract. The medication is also used before various diagnostic procedures, for example, when the patient has to undergo bronchoscopy.

Many doctors also prescribe Fluimucil for sinusitis and otitis, as it facilitates the passage of mucus from the nasopharynx and reduces ear congestion.

“Fluimucil” in the form of granules and ready-made solution can be used from birth, but for children under two years of age this drug is given only as prescribed by a doctor, who calculates the required dose of the active ingredient based on the patient’s weight. Giving the drug to a newborn or infant without medical prescription is contraindicated.

As for the injection form, this type of “Fluimucil” is prescribed to children under one year of age only for health reasons, and the drug should be administered in a hospital. If a child is under 6 years old and it is possible to give medicine by mouth, they try to avoid injection use.

"Fluimucil" is not used in case of hypersensitivity to any of the components in the solution or granules. In addition, the medicine in any form cannot be used in children with exacerbation of gastrointestinal ulcer.

If a child has been diagnosed with kidney, adrenal or liver disease, the use of the medicine requires medical supervision. Granules are contraindicated in patients with phenylketonuria.

For patients with bronchial obstruction or asthma, the medication is prescribed provided there is sufficient secretion drainage.

The drug in ampoules occasionally provokes local reactions, for example, during inhalation a cough, stomatitis or rhinitis may appear, and when injected into a muscle or vein, a slight burning sensation appears at the injection site. In addition, some children, when treated with any form of Fluimucil, experience:

• skin rash;
• heartburn;
• skin itching;
• nosebleeds;
• nausea;
• bronchospasm;
• noise in ears;
• diarrhea;
• stomatitis;
• hives;
• vomit.

If any of these symptoms or other symptoms occur, you should consult a doctor.

The contents of the sachet should be poured into a third of a glass of water, and then given to the child to drink. Stirring the powder is only allowed in glass containers.

If this form of “Fluimucil” is prescribed to a baby of the first year of life, the prepared solution is given from a bottle or spoon. The dosage for infants up to one year is determined by the doctor individually.

For every kilogram of body weight of such small patients, 10 mg of acetylcysteine ​​is required.

For children 1-2 years old, one sachet with 100 mg of the active ingredient is diluted at a time. In this single dose, the medication is given twice a day. For patients 2-6 years old, Fluimucil can also be given in the same dosage, but the dose will be three times. Also, children aged 2 to 6 years can be prescribed Fluimucil twice a day in a single dose of 200 mg.

If the patient is already six years old, then he is prescribed sachets of 200 mg of the active ingredient. At this dose, the medicine is taken 2 or 3 times a day. The duration of treatment is determined depending on the indications - in an acute process, granules are prescribed for 5-10 days, and chronic pathology can be treated for several months.

Under the age of 14 years, a medicine with a concentration of 20 mg/ml is often prescribed. It is given 5 ml to patients 2-5 years old 2-3 times, and to children over 6 years old - 3-4 times a day. Children six years of age and older may be prescribed a more concentrated solution - 4 ml twice a day. For a teenager over 14 years of age, the medication 40 mg/ml is given once in an amount of 15 ml, which corresponds to 600 mg of the active substance.

If the child is from 6 to 14 years old, then he is given intravenous injections once or twice a day, 1.5 ml, which corresponds to 150 mg of acetylcysteine.

Before the injection, the contents of the ampoule are diluted 1 to 1 with glucose solution or saline.

The drug can also be injected into the muscles using a long needle so that the solution penetrates deeply into the muscle tissue. The duration of injection therapy with Fluimucil is determined separately for each child, but it rarely exceeds 10 days.

For procedures, use exclusively the solution in ampoules, using the contents of one ampoule for one inhalation (3 ml). It is recommended to breathe Fluimucil once or twice a day, but sometimes the doctor prescribes three or four procedures a day. The duration of inhalation treatment is usually 5-10 days, but for some pathologies the medication can be used longer.

In addition to inhalation, the solution from ampoules can be dripped into the nose or ear. The dosage and frequency of such use for a severe runny nose, otitis media or sinusitis is determined by the doctor.

Even very high doses of Fluimucil do not have a harmful effect on the child’s body, so there have been no cases of overdose of any form of the drug.

The simultaneous use of Fluimucil and any medications that suppress the cough reflex will lead to a worsening of the patient’s condition, as it will increase stagnation of mucus in the respiratory tract.

There should be a break of at least 2 hours between taking such medications.

When used together with paracetamol drugs, their toxic effect on the liver will decrease. If you give Fluimucil together with medications based on nitroglycerin, the therapeutic effect of such drugs will be enhanced. When injecting, mixing the solution in the same syringe with other medications other than sodium chloride or dextrose solutions is prohibited.

To purchase Fluimucil in ampoules, a prescription from a doctor is required. Other forms of the drug are over-the-counter. The average price of 20 sachets of granules containing 200 mg of active substance in one sachet is 150-160 rubles. For 100 ml of a solution with a dosage of 20 mg/ml you need to pay about 200 rubles, and a package of Fluimucil for injections and inhalations costs about 220 rubles.

All types of Fluimucil should be stored at a temperature of +10+25 degrees in a dry place. The drug should not be freely available to prevent children from finding it. The shelf life of the medicine in granules is 3 years, and in ampoules – 5 years. An opened ampoule can be stored for up to 24 hours in a refrigerator, but is only suitable for inhalation use (a sterile solution is required for injection).

In most cases, treatment with Fluimucil is reviewed positively, calling this medication highly effective and efficient.

The release forms of the drug are called convenient, and most patients like the taste of liquid versions of the drug. Side effects when taking Fluimucil are very rare, and the price of the drug is usually considered acceptable.

The disadvantages of many mothers include the sulfur smell, and in some reviews they complain about the lack of a therapeutic effect.

This drug is produced in the form of a lyophilisate, which can be injected (intramuscularly) or used for inhalation. In addition, this medicine is sometimes prescribed endotracheally, dripped into the nose or ears.

One package contains 3 bottles of medicine with a white or yellowish mass and 3 transparent ampoules with a solvent.

These ampoules contain 4 ml of sterile water, which must be used to dilute the lyophilisate before use.

Once in the patient’s body, the active compound of the drug is broken down to form acetylcysteine ​​(this component thins sputum) and thiamphenicol (this ingredient has an antibacterial effect). “Fluimucil-antibiotic IT” is in demand for prolonged pneumonia, bronchiolitis, whooping cough, bronchitis, lung abscess and other diseases. It is also used for sinusitis, laryngitis or otitis media.

The dosage of the medicine for children is determined by the method of application, and the course of treatment does not exceed 10 days.

Possible side effects of such a medication include allergies or local reactions, and contraindications to the use of lyophilisate are not only hypersensitivity to its components, but also anemia, thrombocytopenia or leukopenia. You can buy the drug only with a prescription , and its shelf life is 3 years.

The most famous analogue of Fluimucil is a drug called ACC. It is produced in effervescent tablets, sachets of granules, syrup and solution for inhalation and injection. This remedy is used for the same indications in children over 2 years of age.

In addition, instead of Fluimucil, the child may be prescribed another drug with an expectorant effect, for example, one of the herbal medicines (Gerbion, Bronchipret, Prospan, etc.

) or a medicine based on ambroxol (“Ambrobene”, “Flavamed”, “Lazolvan”).

For information on how to use Fluimucil, see the following video.

Source: https://o-krohe.ru/otharkivayushchie-preparaty/fluimucil/

Fluimucil: instructions for use for coughs for children and adults, composition, analogues, reviews - Pulmanologist

Fluimucil is a highly effective sputum-thinning pharmaceutical agent.

Available in several variations:

• A solution for internal use without a characteristic color, transparent, with a raspberry taste and a specific smell of sulfur – 20 mg/ml.
• A solution of 40 mg/ml for internal use is transparent with a barely noticeable yellow tint, with a pomegranate-raspberry taste with a slight sulfur aroma. Packaged in darkened glass bottles of 110 ml, 150 ml, 200 ml, packed in cardboard containers.
• Solution for inhalation and injection. A clear, colorless liquid with a slight sulfur odor. After uncorking the ampoule, the solution reacts with oxygen, after which a pink tint with a purple tint is likely to appear. Packaged in clear glass ampoules of 3 ml in blister packs of 5 ampoules, packed in 1 blister pack in a cardboard box.
• Granules for preparing a solution. White with a yellowish tint with an orange aroma and a slight smell of sulfur. Packed in laminated bags. There are 20 or 60 sachets in a cardboard box.
• Effervescent tablets are round in shape, white, rough, lemon flavored, with a slight sulfur odor. Packed in blister packs of 2, 10 tablets of 1, 2, 5, 10 blisters in a cardboard box.

• Active ingredient: acetylcysteine ​​– 20, 40 mg.
• Inactive substances: preservative E218 (para-hydroxybenzoic acid methyl ester), E211 (sodium benzoate), disodium salt of ethylenediaminetetraacetic acid, cellulose gum, saccharin, propylparaben (preservative E216), raspberry, strawberry, pomegranate flavoring and others.
• Active ingredient in 1: acetylcysteine ​​– 300 mg.
• Inactive ingredients: sodium hydroxide, disodium ethylenediaminetetraacetic acid, water for injection.
• Active substance: acetylcysteine ​​– 200 mg.
• Inactive ingredients: sorbitol, aspartame (E951), orange flavor, beta-carotene.

Active ingredient: acetylcysteine ​​– 600 mg and other substances of the inactive component.

Fluimucil is a highly effective phlegm-thinning pharmaceutical agent that increases its quantity and facilitates its removal.

The effect is achieved by breaking the thiol groups of acetylcysteine ​​of intramolecular and intermolecular disulfide bridges of acidic glycosaminoglycans of sputum, causing depolymerization of mucoproteins and a decrease in sputum density. The medicine is active against purulent types of sputum.

There is an increase in the mucoregulatory effect of secretory cells, the ability of microorganisms to adsorb on hard surfaces and sensitive cells with subsequent colonization in the mucous epithelium of the bronchi decreases. The pharmaceutical product activates the mucous membrane of bronchial cells, the secretion of which destroys fibrin.

The same effect occurs in relation to the secretion formed during inflammation in the organs of the respiratory system. Helps inhibit the oxidation of organic compounds caused by the presence of a sulfhydryl group, which neutralizes electrophilic oxidative toxins.

The active ingredient instantly passes into the cell, where it is deacetylated and converted into L-cysteine, from which a short peptide consisting of three amino acid residues is produced: glycine, glutamic acid and cysteine.

Acetylcysteine ​​protects against depletion and increases the production of glutathione, which is involved in reactions that occur with changes in the oxidation states of elements, promoting the destruction and neutralization of various toxic substances.

Protects A1AT from reducing the activity of the influence of NOS 1, an oxidizing agent produced by myeloperoxidase of active phagocytes. The active substance successfully fights inflammation.

When Fluimucil is ingested, it is instantly absorbed from the digestive tract. Passes through the interstitial space, distributed in hepatocytes, kidneys, lung tissues and in secretions from the bronchi. Passes through the placenta.

Fluimucil is excreted through the urinary system in the form of inactive biotransformation products; a small proportion remains unchanged and is excreted in the feces.

The pharmaceutical product is prescribed in the presence of the following range of pathologies that impair the removal of sputum from the bronchi:

• Partial or complete collapse of lung tissue, leading to impaired ventilation of the alveoli.
• Inflammatory processes in lung tissues.
• Inflammation of the bronchial mucosa.
• Inflammation of the small bronchi, leading to their blockage and respiratory dysfunction.
• Inflammatory processes of the tracheal mucosa.
• Cystic fibrosis.
• Bronchiectasis.
• Abscess pneumonia.
• Inflammation of the larynx and the initial parts of the trachea.
• A disease characterized by the development of increased airiness of the lung tissue.
• Diffuse parenchymal lung diseases.
• An inflammatory ear disease that affects the epithelium lining the surface of the middle and inner ear.
• Acute inflammation of the middle ear.
• Inflammation of the maxillary (maxillary) sinus.
• Infectious and inflammatory process in the sinuses or paranasal sinuses (to improve the discharge of mucous secretions).
• Dense secretion in the tracts of the respiratory system during injuries or after surgery (for elimination).

In addition to the listed indications, Fluimucil solution for inhalation and injection is prescribed:

• Before performing tracheobronchoscopy.
• Before X-ray examination of the trachea and bronchi with a contrast agent. Before preparing for active suction of fluid, contents of wounds and cavities using various devices and devices.
• Treatment of channels formed in tissues or organs due to ulcerative processes.
• Treatment of the surgical site during surgery on the mastoid process and nasal cavity.
• Washing the middle ear, respiratory canals of the nose, abscesses, ulcers, accumulation of pus in organs or tissues due to an inflammatory process, maxillary sinuses.

Fluimucil should absolutely not be prescribed for the following pathologies:

• Exacerbation of peptic ulcer of the stomach and duodenum.
• Fructosemia (for a solution of 40 mg/ml).
• Children under 2 years of age (for solution and granules for making solution).
• Children under 6 years of age (inhalation form and solution for injection).
• Up to 18 years of age (effervescent tablets).
• Excessive sensitivity of the body to the active ingredient or other substances of the medication.
• The period of gestation and breastfeeding.

The pharmaceutical drug is used with caution:

Adrenal gland disease.

Discharge of blood from the respiratory tract.

High blood pressure.

Ulcerative lesions of the stomach and duodenum.

Heoptysis.

Phlebectasia of the esophagus.

Bronchial asthma

Liver diseases.

Phenylpyruvic oligophrenia.

Children under 12 months.

The period of gestation.

Solution for internal use. The largest portion of a pharmaceutical product for 24 hours is 600 mg/day.

Adults are prescribed 15 ml of a 40 mg/ml solution once a day.

The instructions for use clearly indicate all recommendations for the use of pharmaceuticals for children:

• 2-5 years – 5 ml of a solution of 20 mg/ml up to 2-3 times a day.
• 6-14 years - 5 ml of a solution of 20 mg/ml up to 3-4 times a day or 4 ml of a solution of 40 mg/ml 2 times a day.
• From 14 years of age and older - 15 ml of a 40 mg/ml solution once a day.

Inhalations. For aerosol therapy, 3-9 ml of a 10% solution is sprayed in ultrasonic devices, and 6 ml in devices with a distribution valve.

Long-term inhalations – 15-20 minutes, 2-4 times a day.

Therapy for acute diseases lasts approximately 5–10 days; for protracted forms of disease, treatment is extended to 6 months.

Since Fluimucil is a highly safe medication, the frequency of use and dosage size may be changed by the attending physician. The adult dose is not changed for the treatment of a child.

• If a high effect of sputum discharge is achieved, then it is sucked out, and the dosage prescribed for the day is reduced.
• To wash the tracheo-bronchial tree during therapeutic examination of the trachea and bronchi using an endoscope, use 1-2 ampoules or more per day.
• 1.5 - 3 ml are dripped into the passage of the outer ear and nose per manipulation.
• Fluimucil is injected into a vein by drop method, slowly in a stream or into a muscle.
• Adults: 3 ml 1-2 times per 24 hours, children from 6 years to 14 – 1.5 ml 1-2 times per 24 hours.

For children under 6 years of age, oral use of the drug is recommended at a daily dose of 10 mg/kg body weight. Administration into a vein for children under 12 months of age is permitted in case of life-threatening diseases and only in hospital.

Before introducing the pharmaceutical into a vein, it is diluted with an isotonic sodium chloride solution or 5% dextrose solution 1:1. The duration of treatment is determined by the attending physician specifically for the individual patient.

The effervescent tablet is diluted in one third of a glass of water. For treatment, it is recommended to take 1 tablet once a day. Acute stages of the disease are recommended to be treated for 5–10 days, protracted diseases are treated for a long time - several months.

When treated with Fluimucil, undesirable effects may develop:

• Epistaxis.
• Tinnitus.
• Digestive system disorders.
• Allergoses of various manifestations.
• An acute form of vascular insufficiency with a sharp drop in blood pressure.
• Uncontrolled prolonged contraction of bronchial smooth muscles with changes in their lumen.
• Decreased reaction of platelets sticking together.
• Inflammation of the mucous epithelium lining the oral cavity.

When treated with a solution for inhalation and injection, the following undesirable manifestations are possible:

• Copious and constant discharge of watery mucous exudate from the nose.
• Respiratory irritation.
• Paroxysmal reflex dry cough, not associated with pathology of the bronchopulmonary system.
• In rare cases, a sudden change in the lumen between the small bronchi and bronchioles as a result of contraction of the muscles of the bronchial wall, inflammation of the mucous epithelium lining the oral cavity.

Injections into the muscle can cause a range of adverse reactions:

• Allergoses.
• A burning sensation in the insertion area.
• With long-term therapy with the pharmaceutical drug Fluimucil, liver/kidney disorders may occur.

For people suffering from bronchial asthma and spasmodic bronchitis, the drug is used with caution and control of bronchial patency.

A light sulfur aroma is characteristic of the active substance of the pharmaceutical product. The ampoule with the inhalation solution is opened just before the procedure. Opened medication should be stored in the refrigerator for no longer than a day.

The medication is injected deeply into the muscle; a burning sensation is felt due to the shallow injection.

The solution, prepared from tablets, granules or ready-made, must not come into contact with metal or rubber surfaces.

When the drug is simultaneously treated with drugs that suppress cough, sputum stagnation is possible due to suppression of cough reflexes.

With parallel treatment with ampicillin, tetracycline, amphotericin B, the effectiveness of all drugs is reduced. It is recommended to maintain an interval between use of more than 2 hours.

The pharmaceutical drug reduces the toxic effects of paracetamol.

Far from access by children and penetration of solar radiation, in temperature conditions up to 25°C.

1. Fluimucil is sold according to a prescription.
2. Switzerland, Zambon Switzerland Ltd
3. The pharmaceutical product Fluimucil has many imported and domestically produced products that are identical in active substance and effect:

• N-AC-Ratiopharm is manufactured in Germany, Ratiopharm, GmbH.
• N-acetylcysteine ​​is a domestic pharmaceutical product, Marbiopharm.
• Acestine is produced in Germany, Stada Arzneimittel AG.
• Acetylcysteine ​​Russian analogue, Vertex JSC.
• Acetylcysteine ​​Canon was released in Russia by Canonpharma Production CJSC.
• Acetylcysteine-Teva German analogue, Salutas Pharma GmbH.
• ACC made in Germany, Salutas Pharma GmbH. Austria, Hermes Pharma.
• Mukobene made in Austria, Merkle GmbH.
• Mucomist analogue of Great Britain, Bristol-Myers Squibb.
• Mukonex made in Turkey, Tripharma.
• Exomyuk was released in Germany, Merkle GmbH.

Source:

Cough drug Fluimucil - release form, composition, active ingredient

Content

Source: https://nyaganngp1.ru/legkie/fluimutsil-instruktsiya-po-primeneniyu-ot-kashlya-dlya-detej-i-vzroslyh-sostav-analogi-otzyvy.html

Fluimucil for cough

Fluimucil is a drug with a mucolytic effect used to treat the lungs and bronchi. The drug is able to effectively dilute mucus and remove it from the lungs. Used to treat cough and other diseases in adults and children.

Compound

	1 sachet for oral solution contains: active substance: 200 mg cetylcysteine; auxiliary components: 25 mg of aspartame, 100 mg of orange flavor, 662 mg of sorbitol, 12.3 mg of betacarotene.
	1 ml of oral solution contains: active substance: 20 or 40 mg acetylcysteine; auxiliary components: 4 mg sodium carmellose, 1 mg disodium edetate, 1 ml purified water, up to pH 6.5 sodium hydroxide, 1 or 1.8 mg methyl parahydroxybenzoate, 1 mg sodium benzoate, 0.4 mg sodium saccharinate, 0.2 g propyl parahydroxybenzoate, 120 mg sorbitol, raspberry, strawberry or pomegranate flavor.
	1 effervescent tablet contains: active substance: 600 mg acetylcysteine; auxiliary components: 20 mg of aspartame, 100 mg of lemon flavor, 680 mg of citric acid, 500 mg of sodium bicarbonate.
	1 ampoule of solution intended for inhalation and injection contains: active substance: 500 mg acetylcysteine; auxiliary components: 3 mg disodium edetate, 3 ml water for injection, sodium hydroxide to pH 6.5.

pharmachologic effect

It has a mucolytic effect - it thins sputum, facilitates its separation, and increases its volume. Acetylcysteine ​​breaks disulfide bonds in mucopolysaccharides of sputum, depolarizing mucoproteins, reducing the viscosity of sputum. With purulent sputum, activity remains.

Prevents the adhesion of bacteria on epithelial cells of the bronchial mucosa. Stimulates cells that synthesize substances that break down fibrin threads. It has a similar effect on the secretion formed during inflammation of the ENT organs.

It has an antioxidant effect due to the presence of the SH group. Neutralizes endogenous and exogenous free radicals, toxins, and has a cytoprotective effect.

Acetylcysteine ​​promotes the detoxification of harmful substances and increases the synthesis of glutathione, which is involved in cellular restoration processes. This explains the effect of acetylcysteine ​​in an overdose of paracetamol as an antidote.

By suppressing the appearance of free radicals that cause inflammation in the lungs, acetylcysteine ​​has a powerful anti-inflammatory effect.

Pharmacokinetics

When taken orally, it is well absorbed. After administration, the maximum concentration in the blood (15 mmol/l) occurs within 1-3 hours. Bioavailability is 10%.

Penetrates between cells, predominantly distributed in bronchial secretions, kidneys, lungs, and liver.
Penetrates through the placenta. Plasma protein binding is 50%. In the liver it is quickly deacetylated to cysteine. In the plasma there is an equilibrium of plasma acetylcysteine ​​and its metabolites (cystine, cysteine, diacetylcystine).

It is excreted in the urine in the form of inactive metabolites, a small part is excreted unchanged through the intestines. The half-life is 1 hour, with liver cirrhosis it increases to 8 hours.

Release form

Fluimucil is available in the following dosage forms:

1. Granules intended for the preparation of a solution for oral administration. Yellow granules with orange splashes, having a characteristic orange smell. There are 20, 30 or 60 sachets in a package. Each sachet contains 1 g of granules.
2. Solution for oral administration. Transparent, has a faint aroma of strawberry, raspberry or pomegranate. Each cardboard pack contains 1 glass bottle with 100, 150 or 200 ml of solution.
3. Effervescent tablets. They have a characteristic lemon, slightly sulfuric odor, a rough surface, white, round. The resulting solution has the smell and taste of lemon flavor. In a cardboard pack there are 1, 2, 5 or 10 packages, 2 or 10 tablets in soft contour packages.
4. Ampoules with solution for inhalation or injection. A colorless solution with a faint sulfuric odor. Each pack contains 5 glass ampoules of 3 ml each.

Indications for use of fluimucil

Fluimucil is prescribed for diseases accompanied by disturbances in sputum discharge:

• tracheitis;
• bronchiectasis;
• pneumonia;
• bronchitis;
• emphysema;
• laryngotracheitis;
• bronchial asthma;
• lung abscess;
• pulmonary atelectasis caused by blockage of the bronchi with a mucus plug;
• cystic fibrosis;
• interstitial lung diseases.

• Also, in order to facilitate the discharge of secretions, the drug is prescribed for sinusitis, sinusitis, purulent, catarrhal otitis.
• In post-operative, post-traumatic conditions, the drug is used to remove viscous secretions from the respiratory tract.
• Indications for use of solution for injection, inhalation:

• washing of the maxillary sinuses, abscesses, nasal passages, middle ear;
• preparation for bronchography, aspiration drainage, bronchoscopy.

Instructions for use of Fluimucil

Fluimucil for cough can be used by both adults and children.

Granules for the preparation of solution for oral administration

Fluimucil granules are taken orally, dissolved in 1/3 glass of water. The duration of therapy is determined individually. Typically, in acute cases of the disease, the course of treatment is 5-10 days. For chronic diseases, the drug can be prescribed for several months.

Drug dosage regimen:

• adults, children over 6 years old – 200 mg 2-3 times a day;
• children 2-6 years old - 100-200 mg 2-3 times a day;
• children 1-2 years old - 100 mg 1-2 times a day.

For children under 1 year of age, the drug is used if there are vital indications, under the supervision of a doctor. Recommended dosage is 10 mg/kg body weight. Fluimucil is given to newborns from a bottle or spoon.

Solution for injection, inhalation

Directions for use:

1. Inhalation therapy. For inhalations lasting 15-20 minutes, a 10% fluimucil solution of 3-9 ml is used. Inhalations are carried out 2-4 times a day. The doctor determines the dosage depending on the patient's condition. For children, the drug is usually prescribed in adult doses. For acute conditions, the duration of the course is 5-10 days, and for chronic conditions – several months.
2. Locally. For otitis and rhinitis, the drug is instilled into the external auditory canal or nose, 1.5-3 ml several times a day.
3. Intratracheal. When performing bronchoscopy, 1-2 ampoules of Fliumucil per day are used for rinsing.
4. Parenterally (intravenously, intramuscularly). Adults - 3 ml 1-2 times a day, children 6-14 years old - 1.5 ml 1-2 times a day, children from 1 to 6 years old - 10 mg/kg per day. It is advisable for children under 6 years of age to take the drug in oral forms. In hospital settings, if there are vital indications, Fluimucil can be administered to children under 1 year of age.

Before intravenous administration, the solution should be diluted in a 1:1 ratio with NaCl solution or dextrose solution.

The duration of therapy depends on the patient's condition. If necessary, long-term use of the drug is possible.

For elderly patients, the solution is prescribed in minimally effective doses.
When taking fluimucil at a dose of 500 mg/kg per day, no symptoms or signs of overdose were found.

Effervescent tablets

Fluimucil tablets are prescribed only to adults. 1 tablet dissolves in a third of a glass of water. The resulting solution is taken orally once a day.

Duration of treatment:

• in acute cases – from 5 to 10 days;
• in the chronic course of the disease - up to several months.

When preparing the drug, you can use only metal utensils, avoiding contact with rubber and metal surfaces. When opening the package, there may be a sulfur smell, which is a sign of the active substance.

Side effects and contraindications

Absolute contraindications to the use of Fluimucil are:

• lactation period;
• exacerbation of duodenal or stomach ulcers;
• individual intolerance to components;
• intolerance to fructose contained in the oral solution;
• for granules, oral solution – age up to 2 years;
• for effervescent tablets – age up to 6 years;
• for solution for injection – age up to 6 years.

Intravenous administration of the drug to children under 1 year of age and administration of effervescent tablets to children under 2 years of age is allowed for health reasons and under the supervision of a specialist.

Fluimucil is prescribed with caution for:

• pulmonary bleeding;
• hemoptysis;
• diseases of the adrenal glands;
• varicose veins of the esophagus;
• arterial hypertension;
• ulcer of the duodenum, stomach;
• pregnancy;
• renal, liver failure;
• phenylketonuria - for effervescent tablets, granules (contain aspartame).

For patients with obstructive bronchitis and bronchial asthma, fluimucil is prescribed with caution, and bronchial patency is constantly monitored.
When administering the drug intramuscularly, people with hypersensitivity may experience a slight burning sensation that quickly passes. With deep injection, no burning sensation is observed.

When administered orally, diarrhea, vomiting, tinnitus, urticaria, nausea, skin rashes, nosebleeds, and itching may occur. There is evidence of the development of bronchospasm, collapse, stomatitis, and decreased platelet aggregation while taking Fluimucil.

Parenteral administration may cause urticaria, skin rash, and mild burning sensation. With prolonged therapy, functional disorders of the liver and kidneys are possible.

Is it possible to use Fluimucil for cough during pregnancy?

The use of the drug during pregnancy is possible according to indications, and the expected benefit to the mother should significantly exceed the potential risk to the child.

When using Fluimucil during lactation, breastfeeding should be avoided.

Compatibility with other drugs

The combination of Fluimucil with drugs that suppress the cough reflex promotes stagnation of sputum.

When Fluimucil is combined with paracetamol, the toxic effect on the liver of the latter is reduced.

Taking antibacterial drugs - tetracyclines (except doxycycline), ampicillin, amphotericin with Fluimucil reduces the effectiveness of both drugs. The break between taking two medications should be at least 2 hours.

Nitroglycerin, when taken with Fluimucil, enhances its vasodilating, antiplatelet effect.

Other medicinal solutions are pharmaceutically incompatible with the drug.

Analogs

Structural analogues of Fluimucil according to the active substance:

1. N-AC-Ratiopharm.
2. Acetylcysteine.acetylcysteine ​​Sediko.acetylcysteine ​​Stada, acetylcysteine ​​Sediko effervescent, acetylcysteine-Hemofarm, Acetylcysteine ​​solution for inhalation 20%, Acetylcysteine ​​solution for inhalation 10%, N-acetylcysteine.
3. Acesitin.
4. ACC, ACC 100, ACC 200, ACC-long. ACC injection.
5. Vicks Active ExpertMed.
6. Mucomist.
7. Mucosolvin.
8. Mukobene.
9. Mukonex.
10. Muko Sanigen.
11. Tussik.
12. N-AC-ratiopharm.
13. Exomyuk, Exomyuk 200.

Conditions, shelf life

1. The drug should be stored at a temperature not exceeding 25°C in a dry place inaccessible to children.

2. When properly stored, the shelf life of effervescent tablets is 3 years, solution for injection, inhalation - 5 years, solution for oral administration in a closed package - 3 years (after opening - 15 days), granules for preparing a solution - 3 years.

3. Opened ampoules of fluimucil are stored in the refrigerator for no more than a day.

Fluumucil in tablets and granules is available without a prescription. The solution is according to the recipe.

Source: http://antritishelp.ru/fluimucil-ot-kashlya

Fluimucil - instructions for using effervescent cough tablets: analogues, how to take them, is it possible for children and during pregnancy

Treatment of many respiratory diseases is based on courses of complex therapy that include antioxidants and mucolytics. The drug Fluimucil has become exactly such a drug of the modern generation.

Description

The pharmacological product called Fluimucil is an effervescent tablet, which you can find out about by reading the manufacturer's instructions. Briefly, the tablets can be characterized as follows: round, quite large, the drug is completely white in color, and has a pleasant lemon smell.

When producing Fluimucil, the manufacturer deliberately chose this form of drug release; despite its size, the tablet quickly dissolves in water, leaving no sediment.

The result is a carbonated liquid with a specific taste and aroma of lemon. Each package of the drug is cardboard and contains instructions for use and blisters with the medicine.

Blisters can contain 10, 5, 2 effervescent tablets.

Attention! The main active ingredient of Fluimucil is acetylcysteine ​​(accounts for 60% of the total mass). Additional components of the medicine are: sodium bicarbonate, aspartame, citric acid, flavorings.

Application

The manufacturer describes in detail the indications for the use of Fluimucil. The medicine is widely used in the treatment of diseases accompanied by cough, both wet and dry:

• tracheitis;
• laryngotracheitis;
• bronchitis;
• pneumonia;
• cystic fibrosis;
• lung abscesses;
• pulmonary emphysema;
• lack of air in the lung tissues (atelectasis);
• otitis;
• sinusitis;
• sinusitis.

Inadequate development of the bronchi, accompanied by periodic suppuration on the mucous membrane of the organ, is also one of the reasons for prescribing the drug. Often, as a result of surgical interventions on the respiratory organs, there is an accumulation of exudate and sputum. To help the substance leave the body faster, Fluimucil effervescent tablets are prescribed.

Important! Taking the drug Fluimucil allows you to speed up the process of liquefaction and removal of sputum in any body.
The drug is used in the treatment of cough

Contraindications

The highly effective medicine has a number of contraindications, as confirmed by the instructions attached to it. Before taking the appointment, you need to find out about them and, if possible, identify or refute them:

• increased sensitivity of the body to the substances included in the composition;
• individual intolerance to the components of the drug;
• age under 18 years;
• gastritis, which occurs in a chronic form, accompanied by the appearance of erosion;
• ulcer of the duodenum, stomach;
• first trimester of pregnancy;
• lactation period at the time of breastfeeding;
• taking other mucolytics.

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Treatment of some diseases involves taking Fluimucil , if there are appropriate indications for use, but this must be done with great care so as not to harm the body.

Among these diseases are:

• bronchial asthma;
• varicose veins;
• problems of blood vessels, heart;
• diseases associated with the development of abnormal metabolism;
• chronic renal and liver failure.

Attention! Fluimucil can be used during pregnancy, starting from the second trimester, but strictly under the supervision of a doctor, after preliminary consultation.

Admission rules

Any mucolytic agent, including Fluimucil for cough, is allowed to be used in complex therapy according to the recommendations of the attending physician.

The specialist, assessing the patient’s condition, selects an individual dosage of the drug, course of treatment, and advises in detail how to take it.

When prescribing a course of treatment, the doctor will necessarily focus on the available indications and contraindications, as well as the patient’s current health status.

Slightly rotating the glass speeds up the dissolution time. The completely clear carbonated liquid is drunk in frequent small sips.

During the day, the recommended dose is no more than 600 mg of the drug (undiluted dosage is indicated).

You can take Fluimucil before or after meals. To prevent the medicine from causing discomfort in the stomach and abdomen, it is not advisable to drink the medicine before meals.

Fluimucil for cough is strictly prohibited for use in the first three months of pregnancy. This has a negative effect on the formation of fetal organs and the development of the small organism as a whole.

At a later date, taking the drug is allowed, but strictly under the supervision of a specialist. The doctor will first weigh the pros and cons, only then, if the treatment is ineffective without it, will he make an appointment.

Important! In fact, the threat to the fetus is minimal, but still exists at any stage of pregnancy. Therefore, even during the “allowed” period, it is better not to use this medication without the advice of a doctor.

During lactation, part of the drug is excreted from the woman’s body along with breast milk. Therefore, doctors strongly recommend that nursing women not take Fluimucil; there are analogues for this. When there is no way out, you need to wean the baby off the breast for a while, and after the active substances leave the mother’s body, continue breastfeeding.

Attention! Fluimucil is strictly contraindicated for children, so it doesn’t matter whether the medicine enters the body through mother’s milk or on its own, such use can result in disastrous consequences for a fragile body.

Side effects

When taking the drug for the first time, you need to be prepared for the fact that the main substances may provoke unexpected side effects. Such a reaction of the body is characterized by possible individual intolerance to the components, or strong sensitivity to them:

• nausea;
• dizziness;
• heartburn;
• belching;
• vomit;
• pain in the abdomen, stomach;
• feeling of discomfort, heaviness in the digestive organs;
• spasm of the bronchi, it seems as if the respiratory organs are compressed or clogged with something;
• allergic reaction;
• swelling of the oral mucosa, nasopharyngeal organs;
• skin rash;
• hives;
• the appearance of extraneous noise in the ears;
• acute form of heart failure (very rare).

to determine on your own whether the drug will cause side effects or not, so when you first take it, it is recommended to limit yourself to only half of the medicinal liquid. If you have already taken Fluimucil or its analogues, then there is nothing to be afraid of.

Considering that the majority of people, when buying Fluimucil, first learn how to take the pills from a doctor or by reading the instructions, there was no official data on recording signs of an overdose. Fluimucil has a unique, strong composition, but if you “know when to stop”, it will not harm your body.

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Interaction with other medicine

When prescribing a course of treatment, the specialist will take into account every detail. First of all, he will try to select medications that will not suppress each other or, on the contrary, enhance the effect on the diseased body.

It is strictly forbidden to combine the drug with antitussive medications that can suppress the functioning of the cough system.

Such a confrontation will lead to the fact that most of the respiratory organs will be clogged with mucus and phlegm, which, when liquefied, will not be able to freely leave the body. Stagnation of sputum in severe cases leads to blockage of the lumens of the respiratory system.

It is not recommended to simultaneously use the medicine with the tetracycline series, since both drugs will be ineffective due to mutual suppression.

The effects of Paracetamol are also reduced by acetylcysteine. A combination of Fluimucil with expectorants made from herbal components (mucolytics) may be useful.

Analogs

The antibiotic Fluimucil has a lot of analogues, the most popular:

• Vicks asset,
• Lazalvan,
• Fluifort,
• Acetylcysteine,
• Acc,
• Azt-long,
• Acestine,
• Mucomist,
• Mukobene,
• Tussik,
• Exomyuk.

The list of medications can be continued by listing pharmacological products that are similar in composition, have the same effect on the body, and the release form may also be different. Some products are significantly different, others are almost identical. When deciding to replace the original medicine with a less expensive one, the consumer often asks the question: which is better - Fluimucil or Acc - how to choose.

The main active ingredient is identical. However, its percentage in ACC is three times less. If in the original each tablet contains 60% of the active ingredient, then the analogue contains only 10%.

Both have different release forms, but ACC solution for inhalation is called differently - Acetylcysteine.

At first glance, the cost of ACC may seem somewhat cheaper, but given the lower ratio of the main active component, the effectiveness will be lower.

Attention! Taking into account the price category of analogues and the original product, the consumer chooses an affordable drug for himself. However, the effectiveness of the original will be many times higher, which is due to the high content of the main active component. In any case, when using Fluimucil or Acc, there will be a therapeutic effect, it all depends on the time of its onset.

Fluimucil antibiotic for inhalation

Caution Antibiotic fluimucil. Don't give this to children! / Benefits of a nebulizer

Conclusion

The market value of a pharmacological product may differ slightly, the average price is 580 rubles. The medicine may seem expensive to many, but this is precisely what explains its effective effect on the body.

Source: https://medicamenty.guru/organy-dyhaniya/fluimutsil-instruktsiya-po-primeneniyu.html