Leukocytes in prostate secretion: norm and deviation in tests

When treating various diseases, examining urine and blood to determine the number of leukocytes they contain is a very important process. These are blood cells that have a nucleus and have no color. White cells in the prostate secretion perform the function of detecting and fighting microbes that harm the human body.

Leukocytes – signal beacons

Penetrating through the walls of the blood supply system, spreading throughout the body, white cells enter the organ that has been exposed to infection. Leukocytes in the prostate secretion, or rather their increased content, signals the occurrence of an inflammatory process. A white cell volume not exceeding 3 billion per liter in men and 6 in women is considered normal.

An increased content (more than 30 billion) of leukocytes in the urine indicates the presence of kidney or genitourinary disease.

Analysis of urine

Urine examination (determining the number of leukocytes) is performed using a microscope. The use of advanced technologies allows you to obtain highly accurate data, while manual labor is reduced to a minimum.

Study of prostate secretion

In order to accurately establish the causes of inflammation of the prostate gland, it is examined.

Prostate secretion is a fluid produced by the prostate gland and is a component of semen. The ability to fertilize sperm depends very much on its characteristics.

The state of the secretion is determined by changes in its composition.

Analysis of prostate secretion juice to identify the disease

Examination of the gland is a common practice in urology, prescribed by a doctor to determine the presence of the disease in the early stages, as well as the degree of ongoing pathological and inflammatory processes. An obligatory step in diagnosing the disease is to study the secretion (fluid is taken for analysis), and based on the results of the glands, the presence of prostatitis in men is determined.

In cases where in patients the leukocytes in the prostate secretion do not exceed the norm, damage to the prostate gland manifests itself in difficult outflow of urine, decreased potency and the manifestation of acute pain syndromes. With such indicators, the doctor refers the patient for a repeat test, since performing one test alone will not allow an accurate diagnosis.

• Analysis of prostate juice is performed for certain indications:
• • pain in the perineum and groin area;

1. • pain when urinating;
2. • establishing the level of fertility;
3. • study of chronic prostatitis.
4. It is not recommended to collect juice during ongoing inflammation, body temperature exceeding 38 degrees, acute hemorrhoids, or cracks in the anus.

Juice collection for analysis

To obtain reliable information, no special preparations are needed before the procedure, but certain prohibitions and restrictions exist. Preparation for the procedure includes:

• abstinence for six days before fluid collection from sexual activity, visiting saunas and steam rooms;
• stopping heavy physical activity on the body per day;
• Alcohol consumption should be stopped two days before;
• daily washing of the genitourinary system to prevent the entry of microorganisms into it.

Results that differ from the norm in one form or another indicate the presence of pathological processes in the prostate. A qualified interpretation of the analysis data will allow the doctor to make the correct diagnosis and prescribe adequate treatment.

The number of leukocytes helps determine the disease. Leukocytes in the prostate juice at a level of 7 to 9 units (the norm is no more than 5) suggest the presence of an infection in the urethral canal or inflammation of the gland that occurred not very long ago.

Exceeding the volume of white cells above 15 units raises the suspicion of chronic inflammation of the prostate gland, an acute process in the urinary tract or urethra.

With an increased content of leukocytes (more than 40 units), in most cases glandular hyperplasia, adenocarcinoma or the process of acute inflammation of the prostate are detected. With hyperplasia, the size of the gland increases significantly.

An increase in white cell content of more than 100 units mainly indicates glandular hyperplasia and acute prostatitis. In order to accurately establish the diagnosis, it is necessary to examine the organ using ultrasound and take a general blood test.

Causes of increased white blood cell count

A slight increase in white blood cells in men, without gland disease, often occurs in the following cases:

1. Sex without a condom and multiple changes of partners. The immune system is overloaded due to frequent contact with women's secretions, and the process of inflammation of the prostate gland begins.
2. Failure to comply with hygiene rules. Irregular washing leads to the entry of microorganisms produced by the glands of the reproductive system into the reproductive organs.
3. Injuries to the lower abdomen. It is possible that leukocytes from inflamed areas may enter the secretion of the gland.
4. Allergy. Leukocytes actively participate in the development of the allergy process.
5. Surgical intervention. Upon completion of genitourinary surgery, the white blood cell count increases as the body responds to damage associated with invasive procedures.

Prevention and treatment methods

There are two types of prevention: primary and secondary. The purpose of the primary is to prevent inflammation of the prostate, and the secondary is to prevent the disease from occurring and becoming chronic again.

Secondary prevention is prostate massage, as well as the use of vitamin complexes. When a disease occurs and after recovery, proper nutrition plays a very important role.

It is necessary to stop eating spicy and salty foods, carbonated drinks, and eat less beans, baked goods and peas. It is also better to put tea and coffee on the “black list”.

The diet should consist of a large amount of vegetables and fruits.

Taking medications must be agreed with your doctor. Traditional medicine recommends eating burdock root; tannins, vitamins, acids and insulin contained in it do not allow negative processes to develop.

Be healthy.

Source: http://proprostatu.ru/diagnostika/lejkotsity-v-sekrete.html

The norm of leukocytes in prostate secretions and the reasons for increasing their number

The prostate gland is an important organ of the male genitourinary system. To monitor her condition, various tests are performed, including examination of the secretion produced.

In a healthy person, all of his indicators are normal, however, due to the presence of pathologies, the composition of the biological fluid changes, for example, leukocytes may appear.

Normally, they are practically absent in secret, so if their number increases, you need to carefully study the situation.

Normal state of prostate secretion

In its normal state, the liquid produced by the gland has a specific odor, transparent or slightly yellowish. When analyzed, you can find in prostate juice:

• water;
• potassium and sodium salts;
• chlorides;
• phosphates;
• protein substances;
• various enzymes;
• epithelial cells;
• amyloid bodies, etc.

The first indicator of normal secretion is considered to be moderate turbidity and liquid consistency. The secretion contains a large number of lecithin grains and a minimal number of red blood cells (no more than one). Ideally, there should be no leukocytes in the composition, but since the juice passes through the urethra, small indicators of their presence should not cause concern.

Medical tables indicate their permissible quantity differently.

Some believe that white blood cells in the prostate gland do not exceed the norm if there are no more than 12 of them, while others define the upper limit at 10.

Depending on the methodology used to analyze the juice, the numbers may look different. For example, when counting white blood cells in a chamber, their concentration per cubic milliliter should not exceed 2000.

Methods for determining the level of leukocytes in secretions

To increase the reliability of test results, it is important for the patient to properly prepare for the procedure. To do this, you must follow the rules below:

• a week before the study, you should exclude sexual intercourse and masturbation, and also refuse to visit baths and saunas;
• two or three days in advance, rectal massage is not allowed;
• you cannot drink alcoholic beverages for two days;
• Serious physical activity is prohibited per day;
• One hour before the procedure you must refrain from smoking.

Some medications may affect test results. To find out which medications you can take and which you cannot, you should consult your doctor.

The collection of material is usually carried out in the morning. The patient is placed on the couch, after which the specialist inserts a finger into his anus.

Important! A week before the procedure, it is necessary to avoid not only overheating, but also hypothermia of the body.

Collecting secretions is a safe procedure, but it has contraindications - acute hemorrhoids, cystitis, anal fissures and tuberculosis microbacteria. Taking biomaterial by stimulating the prostate through the anus is prohibited if a cancerous tumor is suspected.

Decoding the analysis result

Depending on the number of leukocytes in the obtained secretion sample, the doctor determines the type of disease.

If there are no more than nine white blood cells, then such indicators are usually associated with a lack of personal hygiene or errors in the test.

However, sometimes 7-9 units indicate the development of a urethral infection. If the leukocyte level is above ten, then this number cannot be associated with poor hygiene.

Other options:

• 10-15 units may be a sign of an acute form of prostatitis, but they can also be caused by injuries to the glandular organ or recent surgery;
• 15-20 indicate possible chronic inflammation of the gland or bladder disease;
• when approaching 30 units, symptoms of the existing pathology usually appear, which facilitates diagnosis;
• 40 units and above indicate serious prostate diseases.

If more than forty units of leukocytes are found in the sample, then most often this is a sign of hyperplasia or an active oncological process. During the peak period of the acute phase of prostatitis, more than 150 units of leukocytes can be found in the analysis.

As their number increases, the prostate secretion itself will change. It will become too viscous, making ejaculation difficult. The process often becomes painful, which in the long term leads to psychological impotence.

To lower the number of leukocytes, it is necessary to fight the cause of their increase.

How are leukocytes in prostate secretions related to prostatitis?

Prostatitis is the name given to inflammatory processes occurring in the prostate gland. This condition most often leads to an increase in the level of leukocytes in the juice. There are acute, chronic and asymptomatic types of the disease, in which symptoms practically do not appear.

The disease develops for non-infectious and infectious reasons. The first group includes:

• problems with the immune system;

• lack of physical activity;
• abstaining from sexual intercourse or having too much sex;
• hypothermia;
• alcohol abuse and other bad habits.

Infectious causes are associated with other diseases. Most often they are transmitted sexually. This is how bacteria, viruses and other pathogenic microorganisms end up in the prostate gland.

However, prostatitis can be provoked by foci of chronic diseases of other organs. For example, pathology develops against the background of sinusitis, chronic tonsillitis or kidney problems.

At the same time, the entry of pathogenic cells into the organ does not always lead to the onset of prostatitis.

The basis of treatment lies in the use of antibiotics and other drugs that affect the pathogen. The results of treatment for acute prostatitis are noticeable quickly, but the course must be continued for at least a month.

Otherwise, the disease may become chronic. If the pathology is accompanied by clear signs of intoxication, the patient is admitted to hospital treatment.

If you seek help in a timely manner, prostatitis goes away completely without consequences.

Important! An increase in the number of leukocytes can also be caused by a malignant tumor, such as prostate adenocarcinoma.

Other reasons for an increase in the number of white blood cells

If the juice analysis reveals not only leukocytes, but also gram-negative diplococci, then this is a sign of gonorrhea. To confirm the diagnosis, a bacterial culture is required. As with prostatitis, gonorrhea can be treated with a course of antibiotics. Tablets are combined with intramuscular administration of drugs.

Almost any pathology of the genitourinary system affects the analysis of secretions. The disease can be hidden not only in the prostate gland, but also in the bladder. The organs are located nearby and their work is interconnected. Additional research is being conducted to determine exactly where the problem lies.

In addition to disease, elevated white blood cell levels are caused by injury and surgery. For example, if the lower part of the peritoneum is damaged, leukocytes can travel from the source of inflammation to the secretion of the prostate gland.

During operations, the human body produces a large number of white blood cells as a response. Therefore, if the patient's reproductive or urinary organs were affected, leukocytes may later be observed in the urine and secretions.

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Source: https://proctologys.ru/muzhskoe-zdorove/norma-leykocitov-v-sekrete-prostaty-i-prichiny-povysheniya-ih-kolichestva/

Indications and preparation for a study of prostate secretions - normal and abnormal indicators

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An examination of the reproductive system called “analysis of prostate secretions in men” is a simple procedure for examining the prostate gland, the decoding of which will help the doctor determine the cause of diseases and pathological conditions. Prostate fluid affects a man’s reproductive function, so if unpleasant symptoms appear, you should not delay visiting a specialist.

What is prostate secretion

A component of ejaculate in men is a biological fluid of the body called prostate secretion. The composition of the fluid has a direct impact on the ability of sperm to fertilize.

Doctors determine pathological processes by changes in the components of prostate juice.

If there are suspicions of disease or complaints from the patient, a specialist may prescribe a test of the functioning of the male reproductive system - analyze the secretion of the prostate gland.

How do they take it?

Analysis of prostate secretions is a simple procedure. How is prostate juice taken from men? To take the test, the patient lies on his side with his knees to his chest, or stands in a knee-elbow position.

Juice stimulation is carried out by massaging the prostate through the rectum. When carrying out a massage procedure according to the generally accepted method, a special liquid begins to be released, which the specialist collects in a sterile container. If there is no secretion, it is necessary to collect the first portion of urine.

The sediment contains a small amount of prostate fluid.

Why do they take it?

A culture of prostate fluid is taken to identify the cause of pathologies associated with the male reproductive system (cancer, etc.). Also indicators for taking the test are signs found in chronic inflammation of the prostate.

Identifying the symptoms of this disease is very problematic. An analysis of prostate secretion will show the quality of sperm (which is especially important in case of male infertility), the causative agent of inflammation, and will determine the effectiveness of the prescribed treatment.

Other indications for the study are the presence of the following symptoms in men:

• pain in the lower abdomen or perineum;
• decreased potency and male libido;
• problems with urination (weak stream of urine);
• lack of erection;
• discharge with an odor from the urethra;
• urinary incontinence;
• the urge to urinate at night.

Study of prostate secretion

Preparing for the research procedure is simple. On the day of collection, it will not be superfluous to give a cleansing enema.

Preparation for the donation of prostate secretions includes general recommendations: abstinence from sexual intercourse a week before the date of the test, a ban on alcohol, baths and saunas, and a reduction in physical activity.

The laboratory may conduct a special test to determine pathology. It reveals the “fern symptom” and is produced as follows: the liquid is mixed with saline. Normally, when dry, the pattern will look like a fern. Analysis of prostate juice is divided into 2 methods of study:

• microscopic;
• bacteriological.

Microscopic

Through a microscopic examination of the secretion of the prostate gland, the doctor studies the cellular structure of the fluid of the glandular-fleshy organ.

Microscopy of prostate secretion is carried out as follows: a drop of secretion is examined by a specialist under a microscope. The liquid is placed on a glass slide and covered with a coverslip.

If the analysis results are good, one cannot speak of the absence of inflammation. If treatment is not timely, blockage of the excretory ducts occurs.

Bacteriological

The specialist prescribes a treatment regimen only after the results of a bacteriological examination.

It is necessary to undergo tests for prostatitis, with the help of which the doctor identifies the type of microorganism that is the cause of the inflammatory process. The described procedure is otherwise called “prostate fluid culture.”

If there is no growth of pathogens, closed infectious foci may be observed, so the doctor prescribes re-seeding.

Interpretation of prostate secretion analysis

An accurate diagnosis occurs after receiving the results of the analysis, which is deciphered only by a doctor. Bacteriological culture of prostate secretion will help determine the presence of fungi, bacteria and other pathogenic microorganisms.

Using the information obtained, you can find out the type of pathogenic microflora, the number of bacteria and find a group of antibiotics to which the microbes will be most sensitive.

Microscopy of an unstained specimen will tell laboratory technicians about the presence, absence or quantity of the following characteristics:

• leukocytes;
• giant cells (macrophages);
• red blood cells;
• epithelial cells;
• lecithin grains;
• amyloid bodies.

Leukocytes

The function of white blood cells is to support the immune system. A small amount of leukocytes is allowed in the body - up to 5 cells. Ideally, there should be no component in the prostate juice, but the presence of leukocytes in small quantities does not indicate inflammation.

When taking the test, a few cells may penetrate into the container, since the prostate secretion passes through the urethra. During the inflammatory process, the prostatic fluid becomes viscous and the excretory ducts become blocked.

This phenomenon makes it difficult to know the exact number of cells.

Amyloid bodies

A procedure for examining the state of prostate juice, such as microscopy, will help detect amyloid stones. Exceeding their number indicates the presence of advanced stage prostatitis, stagnation in the gland, the presence of adenoma and inflammation.

Amyloid bodies are a clot of prostate juice that has an oval shape. In the test results of a healthy man, no bodies are found.

In older people, the risk of finding amyloid stones is much higher than in young men.

Betcher crystals

Specific crystals were discovered by Boettcher in male semen and are needle-shaped clusters that crystallize when prostate juice and sperm dry and cool. The substance should not be present in the material being tested. The presence of crystallization indicates oligozoospermia, azoospermia, and inflammatory processes.

Macrophages

The number of macrophages in the gland juice should not exceed one. The levels of this substance increase with fluid stagnation in the prostate or chronic inflammation.

A significant number of macrophages is a prerequisite for carrying out bacterial culture when the causative agent of the inflammatory process is undetected.

Macrophages are a type of white blood cell, otherwise known as monocytes, that are involved in fighting infections.

Lecithin grains

Lipoid (lecithin) grains are non-cellular formations that make up 1/2 of the total secretion. The analytes are normal prostate epithelial cells.

The entire field of view should be covered with these compounds.

In normal analysis results there are a large number of them, but a decrease occurs during stagnation, indicating prostatitis or human fertility.

Epithelial cells

When analyzing secretions by massaging the prostate gland, a small amount of epithelial cells - connections of the prostate ducts - may be detected.

When viewed under a microscope, there should be no more than two compounds in the field of view. Exceeding the norm indicates inflammation of the prostate tissue.

A result of 15 cells shows desquamatous inflammation - peeling of the epithelial lining.

Flora

A single amount of some types of rods or cocci may be observed in the flora, which does not indicate pathology.

A sign of nonspecific inflammation is a huge number of opportunistic microorganisms.

Bacterial prostatitis causes an abundant manifestation of pathogenic flora, which the laboratory technician will definitely notice in the analysis results. The state of the flora is determined through bacterial culture, contraindications to which are:

• body temperature from 38 degrees;
• anal fissures;
• haemorrhoids;
• prostate tuberculosis.

Fungi

If a man has Candida fungus in his body, fungal prostatitis (candidiasis) may develop. When the immune system is normal, the fungus does not manifest itself in any way.

When the body's defenses decrease, a pathological process begins. Fungi are detected by analyzing prostate secretions through massage.

There are 2 ways of infection with fungal prostatitis: through the urethra (ascending) or through the bloodstream (hematogenous).

Normal and abnormalities in the analysis of prostate secretions

Only a doctor can reliably recognize abnormalities and determine the presence of inflammation. When reading test results independently, errors are possible, which can be followed by incorrect treatment. A timely visit to a specialist will help to correctly diagnose the disease. Main indicators of deviations and normal values:

Secretion indicators Norm Deviations

Color	white	yellow tint, blood
Smell	the smell of sperm	any other
Acidity (pH)	6.4-7.0 (slightly acidic or neutral)	alkaline or acidic environment
Density	1,022	change above normal
Slime	absence	present
Red blood cells	none	There is
Epithelial cells	from 1 to 2 in the field of view	quantitative value greater than 3
Amyloid bodies	minimal amount	There is
Macrophages	absent or isolated	sharp increase
Lecithin grains	10 million/ml	reduced number

Video: analysis of prostate secretion

Analysis of prostate secretions

Attention! The information presented in the article is for informational purposes only. The materials in the article do not encourage self-treatment. Only a qualified doctor can make a diagnosis and give treatment recommendations based on the individual characteristics of a particular patient.

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Source: https://sovets.net/11755-analiz-sekreta-prostaty.html

Leukocytes in prostate secretions: norm, deviations, analysis, reviews

To understand that an inflammatory process is occurring in the male reproductive system, leukocytes in the prostate secretion help specialists. After all, normally this biological fluid is practically sterile. Defender cells - leukocytes, when a threat appears, begin to attack infectious microorganisms and die. This process is studied by laboratory assistants when studying prostatic juice.

Role of leukocytes

Since in a healthy man the prostate gland is located in the pelvis and does not have direct communication with the external environment, the biological fluid it secretes - juice - is sterile. The presence of epithelial cells, proteins with carbohydrates and electrolytes is acceptable in its composition. But there should be a minimum number of them.

However, as it passes through the urethra, additional substances are added to the gland juice. By their high concentration, doctors determine the course of the pathological process in the urinary system - infection.

They secretly perform a barrier function - they try to neutralize the aggressive factor. With their help, the immune system recognizes and suppresses the development of an infectious disease. An analysis where the number of leukocytes exceeds 8–10 units indicates the hidden/overt appearance of a pathological focus.

Leukocytes in prostatitis can be diagnosed using two methods - laboratory testing of prostate juice directly or a three-glass urine sample. Additional procedures - bacterial analysis of a smear from the urethra, ultrasound of the pelvic structures - will allow you to recognize what kind of infection has entered the man’s body and what organ it has affected.

Norm and deviations

Under natural physiological conditions, the analysis of prostate juice is normal, leukocytes in the prostatic fluid are minimal.

In the field of view of a laboratory technician who examines biological material, their number ranges from 0 to 12 units.

If the patient has repeated complaints - discomfort in the pelvis, worsening urination, weakening of potency, the diagnosis of prostatic juice can be repeated.

When the protective cells increase by 2–3 times or more, this indicates acute damage to the organ. For example, a specific infection - gonorrhea, trichomoniasis.

Additional diagnostic procedures will be required.

Doctors must take into account possible age-related deviations in the numbers of white protective cells - they can either decrease or increase, but only slightly.

For example, the borderline criterion of 10–12 leukocytes is a consequence of previously suffered acute prostatitis or trauma to the genital organs.

Whereas the detection of 50–60 leukocytes in the analysis of prostate juice is alarming about the possible formation of a tumor focus in the pelvis.

How to determine the number of leukocytes in prostate secretions

You can find out that they are elevated in the secretions of the prostate gland in two ways:

1. Collect and submit for research biological material directly from the ducts of the male organ. In laboratory conditions after preliminary massage of the organ.
2. Microscopic examination - a three-glass urine sample. Which allows you to simultaneously evaluate the functioning of different structures of the urinary system, not only the kidneys, but also the prostate.

Often, to diagnose pathologies of the male reproductive system, especially hidden ones, doctors prefer to prescribe both methods of obtaining information about the composition of the prostatic fluid. If the test results are contradictory or ambiguous, for example, due to failure to follow the rules of the preparatory stage, the specialist will order a repeat examination.

Preparing for analysis

Correctly assessing them in the prostate gland, or rather in its juice, will be much easier if the man understands and follows all the doctor’s recommendations at the preparatory stage. There should not be any difficulties, because the actions do not require special knowledge and skills.

Basic rules for preparing for research:

• refrain from sexual contact with your partner for 5–7 days;
• adjust your diet - the menu should not contain spicy, smoked, fatty, fried, heavy dishes with spices and sauces/condiments;
• avoid local/general overheating or freezing of the tissues of the groin area;
• prevent injuries to the genital structures;
• It is better to minimize physical/psycho-emotional stress;
• carefully observe personal intimate hygiene;
• alcoholic beverages are completely prohibited for 1–2 days;
• Do not self-medicate - take all medications only after consultation with your doctor.

On the day of the study of leukocytes and pathogenic flora in the juice of the organ, the man comes to the laboratory room for taking biomaterials mentally prepared, with a form from the doctor. He should refrain from smoking 2-3 hours before the examination, take a hygienic shower in the morning and put on fresh underwear.

Material collection

The diagnostic procedure - obtaining biomaterial from the prostate ducts - is performed exclusively in a medical office and not at home. At the same time, the psychological burden and excessive shyness of men are not taken into account. The urologist and nurse are wearing sterile gloves to prevent infection.

As a rule, the study is carried out in the morning, when the subject’s body has rested, and possible negative factors that could distort the result of the analysis are minimized. The procedure is carried out by an experienced specialist.

The man is placed on the couch on his left side with his knees brought to the sternum, or he is asked to take a knee-elbow position. After which the gland is massaged through the rectal canal.

The duration of the examination is 3–5 minutes.

Determination of content in urine

If massage of the prostate, due to objective reasons, did not allow obtaining its juice for laboratory diagnosis, then leukocytes in the urine for prostatitis should be examined. They are definitely included in it.

However, for the study, not just the morning portion of urine is collected, but with certain nuances observed. For example, the entire volume of urine needs to be distributed into three clean containers - 1/4 of the liquid in the first and last, and ½ of the liquid in the middle container. All containers must be labeled and sent to the laboratory for study.

A specialist can make a preliminary conclusion about the state of a man’s genitourinary system based on which portion of urine contains an increase in the number of leukocytes. So, urethritis - if in the first container, and cystitis - due to leukocyturia in the second container. Whereas problems with the organ are indicated by a large number of white blood cells in the third portion of urine.

Tank sowing gland juice

If it is necessary to clarify not only the number of protective cells in the prostatic material, but also to identify the causative agent of the pathological process in the male organ, then the juice is sent for bacteriological examination - bacterial culture.

After it is placed on a special nutrient medium, pathogenic microorganisms grow in their colonies, which will be clearly noticeable to the expert laboratory assistant. However, such an analysis requires a lot of time - at least 10–14 days. But it is possible to determine which type of antibacterial drugs infectious agents will be especially susceptible to - an antibiotic sensitivity test.

Microscopic examination of the composition

Prostatic juice itself is a kind of opalescent liquid. Which has a specific smell and a slightly viscous consistency. Its color resembles slightly diluted milk. Typically, about 2 ml of biological substrate is released.

Its microscopic composition:

• white blood cells - leukocytes;
• calcium and potassium salts with sodium;
• lipoid cells;
• macroelements - zinc, chlorides, phosphates, and citrates;
• epithelial particles.

Normally, the reaction of prostatic juice is neutral. Less often slightly acidic - due to the presence of phosphatase and citric acid in a minimal amount.

Who is the test contraindicated for?

It is necessary for all representatives of the stronger half of humanity to clarify their norm in prostate secretions after 40–45 years of age - during the period of undergoing a preventive medical examination. However, there are a number of limitations to such a survey:

• suspicion of tuberculosis damage to the organ;
• malignant neoplasms in the gland;
• acute period of hemorrhoids;
• anal fissure at the time of exacerbation;
• the first days of cystitis.

The listed conditions in the pelvic area can distort the reliability of laboratory diagnostics. Therefore, the specialist must carefully collect not only the patient’s complaints, but also the history of his illness, life and professional activity.

Other laboratory tests

It is possible to clarify whether leukocytes in the gland are elevated or not using other laboratory procedures - not only taking biomaterial directly from the ducts of the gland. In a situation where contraindications to the removal of prostatic juice have been identified, alternative diagnostic methods can be used.

For example, a tank is used to inoculate the contents of the urethral canal - cells are taken using a device called a Volkmann spoon. They are placed in a nutrient medium and observed to see if bacterial colonies grow.

Another informative study is a smear from a man’s urethra. Under a microscope, a specialist sees both the number of leukocytes and the presence of other accompanying substances, which normally should not be present.

Reasons for the increase

The physiological reasons why they are elevated in prostate juice are different. Starting from sexual intercourse without the use of barrier contraception on the eve of a laboratory visit, to allergic reactions to taking certain products/medicines. Before repeating the study, the specialist explains in detail and carefully to the men the rules for preparing for such a study.

Other reasons for violations in the analysis:

• abdominal and pelvic injuries;
• surgical interventions in the structures of the urinary system;
• latent course of prostatitis;
• specific sexually transmitted infections;
• prostate neoplasms.

For differential diagnosis, urologists recommend additional studies. From PCR blood tests for infections to MRI/MSCT of pelvic structures.

How to bring leukocytes back to normal

Since in most known cases, when they are elevated in the gland juice, the root cause is an inflammatory process in the tissues of the organ, doctors strive to first eliminate the provoking factor.

Conservative therapy consists of a complex effect on the lesion:

• taking medications from different subgroups - from a massive antibacterial regimen to anti-inflammatory drugs and vitamin-mineral formulations;
• nutrition correction – selection of food from products that help increase the male body’s own defenses, especially fresh vegetables/fruits, cereals, meat/fish, fermented milk drinks;
• physiotherapeutic procedures - magnetic therapy, electrophoresis with medicinal solutions, laser therapy, acupuncture.

No less important is a man’s desire for a healthy lifestyle. This is giving up bad habits, for example, abuse of tobacco and alcohol products. If necessary, doctors consider surgical intervention - excision of large gland stones and tumor foci.

Prevention measures

Following simple preventive measures helps men prevent the possibility of an increase in the number of protective cells in prostatic juice:

• careful adherence to personal hygiene - daily shower, change of underwear;
• sexual contacts with partners exclusively using barrier contraception measures;
• proper nutrition - the predominance in the diet of not only vegetables and fruits, but also different types of meat/fish, herbs, cereals, dairy products;
• balance between work and rest;
• absence of excessive physical/psycho-emotional overload;
• a good night's rest - sleep at least 7-8 hours in a ventilated, cool room;
• avoiding physical inactivity/pelvic injuries;
• prevention of constipation;
• timely treatment of chronic foci of infection in the body.

When all preventive measures are taken, a man remains sexually active and healthy into old age. He does not require course treatment for diseases such as prostatitis.

Reviews from doctors and patients

Pavel Valentinovich, 45 years old, urologist:

Caring for the health of the male gland is a set of measures that must be taken not only by the doctor, but also by the patient himself.

For example, if there are warning signs from the prostate - soreness, sluggishness of the urine stream, then you should immediately undergo an examination.

Laboratory diagnostics - analysis of prostatic juice for leukocytes will allow the doctor to assess the health of the gland and promptly prescribe the correct treatment.

Denis Makarovich, 51 years old:

Faced with a problem in the urinary system - itching and burning when urinating, I immediately turned to a urologist at the clinic. I was prescribed a series of examinations, including a study of prostate secretions for leukocytes.

The procedures were somewhat uncomfortable, and I had to overcome my shame. But the information from the tests was enough for the doctor to understand what caused the gland disorder.

After complex treatment, my health quickly returned to normal.

Watch the video :

Source: https://mensgen.ru/prostate/lejkotsity-v-sekrete-prostaty.html

Leukocytes in prostate secretion

Prostate secretion is one of the most important components of male seminal fluid. A viscous, cloudy substance is produced in the prostate gland and contains various proteins, fats, carbohydrates, hormones and electrolytes.

With any disruption of the functioning of the gland, the composition of prostate juice undergoes significant changes, tracking which, it is possible to diagnose a particular disease with a high degree of probability.

Photo 1: Microscopic examination of prostate secretion involves measuring the quantitative composition of lecithin grains, various microorganisms, as well as leukocytes - white blood cells. Source: flickr (Bryan Jones).

Prostate juice analysis: diagnosis

Analysis of prostate secretions is used to obtain information about the condition of the organ and possible deviations from its normal functioning.

Based on the results of the analysis, the doctor can diagnose:

• Prostatitis that occurs without pronounced symptoms.
• Chronic prostatitis of bacterial nature.
• Chronic pelvic pain syndrome.
• Urinary disorders (transient dysuria).
• More dangerous diseases such as prostate hyperplasia or adenocarcinoma. 

Note! A single analysis of prostate secretions may not be enough to obtain a guaranteed accurate diagnosis. In some cases, additional research may be required.

Presence of leukocytes in prostate juice

The presence of leukocytes in the juice of the prostate gland does not always indicate inflammatory processes in the prostate.

The gland itself is located in close proximity to the bladder and urethra, as a result of which even in a healthy man a certain number of white blood cells can appear in the secretion. Up to 5 units of leukocytes per field of view is considered normal.

A slight excess of this threshold may also not be associated with inflammatory processes , but may be a consequence of a man’s lifestyle:

• Insufficient hygiene of the male genital organs. Microorganisms that accumulate on the penis may well penetrate the prostate.
• Promiscuous sexual intercourse. Frequent changes of partners, each of which has a unique composition of biological fluids, significantly increases the load on a man’s immune system. This provokes an increase in the production of leukocytes.
• Injuries or consequences of surgical operations in the pelvic area. In this case, leukocytes can enter the prostate from the site of damage.
• Allergic reactions. White blood cells play an important role in allergic reactions. In prolonged forms of allergies, leukocytes can also enter the prostate secretion.
• Quite often, the presence of leukocytes in prostate juice is explained by pyelonephritis. Bacteria from the kidneys can enter the urinary tract.  

Higher rates in the analysis of prostate secretions give reason to think about the development of certain pathological conditions in the pelvic area.

It is important! Careful hygiene in preparation for the test helps to avoid the release of random leukocytes into the secretion and makes the test results more believable.

The form of pathology can be more accurately determined by the number of leukocytes in the prostate juice: 

• A level of 7-9 units suggests that the patient has an infection in the urethra, or has recently suffered inflammation of the prostate.
• Indications at the level of 15-20 units may indicate the presence of a chronic form of prostatitis, or inflammation in the urethral canal or bladder. To more accurately determine the diagnosis, a man may be prescribed a cytoscopy, urethral smear, or ultrasound.
• 40-80 leukocytes per field of view are observed in patients with adenocarcinoma (malignant tumor of the prostate) and glandular hyperplasia. The beginning of an acute inflammatory process in the prostate gland can manifest itself in a similar way.
• A leukocyte level of 100 units or more can be observed in men with acute prostatitis or glandular hyperplasia. 

Many patients delay the test procedure until the last minute, experiencing a feeling of awkwardness and discomfort. Under no circumstances should this be done. If the doctor orders prostate secretion to be analyzed , it is necessary to take it as soon as possible .

Photo 2: The analysis will help to promptly identify dangerous male diseases and take measures to eliminate them. Delay can affect a man’s sexual health in the most negative way. Source: flickr (Eugene Evehealth).

What may affect the results of the study?

In order for the analysis result to show the most plausible results, it is worth preparing for it in a certain way: 

• At least 5 days before the test, abstain from sexual intercourse.
• Two days before the due date, stop drinking alcohol, and 1.5-2 hours - tobacco.
• Avoid visiting the bathhouse or sauna for at least a week.
• Avoid strenuous physical activity before the procedure. 

A lot depends on the medical workers themselves. The procedure for collecting prostate secretions must be carried out with maximum care and compliance with all sterility standards.

Source: https://vylechim-prostatit.ru/prostata/leikocity-v-sekrete-norma-i-otkloneniya-165

Elevated leukocytes in prostate secretions: causes, solutions

Under normal conditions, prostate juice is sterile, but as it passes through the urethra, various substances are attached to it. During the onset of pathology, the juice consists of various impurities.

Leukocytes in prostate secretions make it possible to determine deviations from the normal functionality of the genitourinary system with maximum accuracy. If the indicator is normal, the patient is healthy.

But when the number of leukocytes exceeds the normal state, a specialist can conclude that there is a chronic or acute pathology.

The number of leukocytes in prostate juice: normal and abnormal

Prostate secretion is a substance that has a specific odor. The juice is the result of the activity of the prostate gland. Under natural conditions, the secretion is part of the sperm, providing sperm with the ability to fertilize.

If, after analyzing the secretion, a man is concerned about the prostate gland, a repeat examination is carried out 14-20 days later. This is due to possible blockage of the ducts with thick prostate juice. If, according to the results of the second study, the leukocyte level is above 12 units, the specialist concludes that prostatitis is present.

Modern equipment in the laboratory involves the use of the following analysis methods:

• leukocyte – study of prostate juice using a special formula;
• determination of the number of leukocytes in 1 ml of a sample taken from a patient.

Table of possible diagnoses in accordance with the indicators based on the analysis results:

Indicator value (in units)	Description
7-9	The indicator indicates the presence of infection in the urethral canal and violation of hygiene rules. The result may also be due to a violation of the collection technique. In this case, additional research needs to be done. The specialist writes an appointment for urethral culture
10-15	It is observed in men who have undergone acute prostatitis or surgery on the genitourinary system. The indicator may indicate the presence of injuries
15-20	The numbers may indicate an inflammatory process in the prostate of a chronic nature or an acute disease of the bladder or urethra. In order to clarify the diagnosis, it is recommended to do an ultrasound and a smear from the urethra
20-30	Most often, with this indicator, the diseases are the same as with figures of 15-20 units
40-50	The indicator indicates serious abnormalities in the functioning of the prostate
60-80	Occurs in adenocarcinoma and benign hyperplasia. A large indicator is due to the fact that the immune system is activated and cannot cope with pathologies
80-100	Advanced state of the tumor, but without indicating the nature of its occurrence
Above 100	Advanced form of hyperplasia. The disease progresses and cannot be avoided without surgical intervention.
More than 150	Acute prostatitis with inflammation

Causes of increased levels of leukocytes in the prostate gland

In order for a specialist to make an accurate diagnosis, it is recommended to undergo a comprehensive examination , because an increased number of leukocytes in the secretion of the prostate gland may indicate various diseases.

Other possible causes of an increased white blood cell count:

1. Prostatitis. In most cases, with a high leukocyte count, chronic prostatitis is diagnosed, which can be caused by both bacteria and non-infectious causes (blood stagnation due to low physical activity).

When bacterial prostatitis appears, bacteria are found along with an increased level of white blood cells. Next, their type is determined in order to prescribe an antibacterial drug.

If no bacteria are detected, the disease is antiseptic or stagnant in nature. Treatment is carried out without the use of antibiotics.

1. Benign hyperplasia. The disease is caused by a benign tumor in the prostate tissue. The disease most often appears in older men. At the initial stage, hyperplasia has symptoms similar to chronic prostatitis.
2. Gonorrhea. An increased white blood cell count accompanied by gram-negative diplococci indicates an increased likelihood of gonorrhea. To make an accurate diagnosis, it is necessary to perform a bacterial culture of the secretion.
3. Diseases of the genitourinary system. An inflammatory process in the bladder or kidneys can affect the white blood cell count.

The most common cause of inflammation in the prostate is the occurrence of infections that enter the body as a result of exposure to various factors (hypothermia, decreased immunity, frequent changes of partners). The main causative agents of the inflammatory process are chlamydia, trichomonas, staphylococcus.

1. Prostate adenocarcinoma is a malignant tumor into which the prostate glands degenerate. Timely diagnosis helps detect prostate cancer in the early stages and successfully treat it.

Slight increase in white blood cell count

A man's body is constantly in contact with microbial cells in the environment, so a slight increase in the level of leukocytes is allowed.

Some reasons that can lead to an increase in leukocytes in the prostate secretion without pathology of the body:

1. Violation of personal hygiene. Men constantly secrete lubricant, which is a medium for the development of microorganisms. If hygiene rules are not followed, bacteria penetrate the urethra and then into the prostate gland.
2. Increased sexual activity. Constant contact with sexual partners is stressful for a man. The body secretes a large number of white blood cells in order to fight bacteria and microbes that enter the reproductive system.
3. Surgery on the genitourinary system. Medical operations lead to an increase in white blood cells immediately after the intervention.
4. Injuries. If a man has injuries to the genitourinary system, white blood cells will be released in high quantities in order to combat changes in the body.
5. Allergy. When an allergic reaction occurs, white blood cells play an important role.

Treatment of an increased number of leukocytes in prostate secretions

The treatment procedure should be established by a specialist after all examinations. Therapy is aimed at reducing influencing factors:

• if the number of leukocytes increases due to infections in the body, the patient is prescribed antibacterial drugs;
• in the presence of inflammation, steroid medications are used, which help reduce the concentration of leukocytes in the male body.

After 40 years of age, a mandatory diagnostic test includes taking blood for PSA.

Only if indicated, a study is carried out for the presence of leukocytes in the secretion of the prostate gland.

Source: https://gormons.ru/zhelezy/predstatelnaya-zheleza/povyshennye-lejkotsity-v-sekrete-prostaty-prichiny-sposoby-ustraneniya/

Increase in leukocytes in prostate juice

White blood cells in prostate secretions may indicate the presence of inflammatory or bacterial diseases. The analysis is not always able to indicate the exact disease, so in some cases additional examinations are carried out. To normalize the indicator, medications and physiotherapeutic procedures are prescribed.

Function and causes of increased leukocytes

In the complete absence of pathologies, an analysis of prostate juice should show the complete absence of any impurities other than those that make up the secretion. But as it passes through the urethra, various particles and other substances can be added to it. Their analysis can give an idea of ​​the presence and determine the disease.

Leukocytes are cells in the blood that perform the body's immune function. When any part of the body is inflamed, their concentration there will be increased. Accordingly, leukocytes in the secretion of the prostate gland, when their level is high, can indicate the presence of an inflammatory or bacterial pathology.

The level of leukocytes in prostate secretions does not apply to the final diagnostic procedures, therefore, after its analysis, additional diagnostic procedures will be prescribed to accurately identify the pathology.

Method for determining leukocytes

This indicator can vary from many factors (presence of injuries, poor hygiene measures, frequent sexual intercourse with different partners, interruption of sexual intercourse, allergies, improper collection of secretions for analysis), therefore, to establish a more accurate picture, not only the secretion is examined, but also an analysis is taken 3 cup urine sample.

The collected material is analyzed for the presence of the following particles:

1. Leukocytes.
2. Lecithin grains.
3. Epithelial cells.
4. Amyloid bodies.

The crystalline network of sodium chloride, which is part of the prostatic secretion, can also be studied. If it has the correct structure, then there is no disease. If it is deformed, this is additional evidence of the presence of prostatitis.

Before conducting the analysis, doctors recommend adhering to the following conditions 2-3 days in advance:

1. Refrain from sexual intercourse.
2. Prevent hypothermia.
3. Do not be exposed to physical stress.
4. Stop drinking alcohol.

Interpretation of leukocyte analysis results: norms and deviations

Normally, the indicator ranges from 0 to 10 units in the field of view. Elevated levels may indicate the presence of the following diseases in men:

• hyperplasia;
• varicocele;
• pathology of the bladder;
• BPH;
• adenocarcinoma.

In addition, bacteria or their metabolic products may be present in the prostate juice, which indicates the presence of bacterial prostatitis. Also, if gram-negative diplococci are detected, a diagnosis of gonorrhea can be made.

To interpret the results of the analysis, the following scale is used:

• 7-9 units – infection of the urethra, improperly performed hygienic procedures, or improper collection of material;
• 10 to 15 – indicates recent surgery, trauma or a previous acute form of prostatitis;
• 15 to 20 – indicates chronic inflammation of the prostate, acute inflammation of the urethra or bladder. To clarify the pathology, additional examination is used;
• 20 to 40 - in the presence of external symptoms, a diagnosis of the same diseases is established as with 10 - 20 units, if this is not possible, an additional examination is prescribed;
• 40 units are observed in acute prostatitis;
• 50 – 60 – these indicators are present in hyperplasia or adenocarcinoma;
• 65 to 100 – this level of leukocytes is observed in advanced oncological processes. To accurately establish the diagnosis, additional procedures are prescribed - MRI, CT, PSA test and puncture;
• more than 100 units – an advanced form of hyperplasia in the stage of active development. Surgery is required;
• more than 150 units – acute form of prostatitis at the peak of the inflammatory process.

Treatment

If leukocytes in the secretion of the prostate gland are elevated after surgery, then treatment is not prescribed, because this is a transient condition that normalizes over time.

Treatment occurs in accordance with the diagnosis and after consultation with a urologist. Can be assigned:

1. Medicines, in particular NSAIDs, antibacterial drugs and androgens. The course and dosage is established by the urologist in each individual case.
2. Physiotherapeutic procedures - electrophoresis, exposure to a magnetic field or laser, acupuncture.
3. Preventive measures - active lifestyle, getting rid of bad habits, etc.
4. Diet - avoidance of foods that irritate mucous membranes and contain cholesterol, limit the amount of fluid consumed in the afternoon, and use vitamin complexes. “Healing table number 5” is taken as a basis.

Preventive measures and diet do not directly affect the level of leukocytes, but they reduce adverse reactions from medications, promote their better action and remove excess blood cells. It is impossible to do this instantly, but with proper treatment their level will gradually decrease to normal.

Source: https://prostatity-net.ru/prostata/diagnostika/lejkocity-v-sekrete-prostaty.html