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The most common causes of prostate adenoma in men

It tells in detail about the causes of prostate adenoma in men. They describe hormonal causes, as well as factors depending on a man’s lifestyle. Explanations are given for each reason.

Any human disease is provoked by some factors, everything has a reason. Prostate adenoma has causes, and by learning about them, a man can prevent the occurrence of the disease. Even simple correction of the disease development factors can stop it, even if it already exists.

Hormonal reasons

Estrogen and androgen are two opposite hormones. Estrogen is a female hormone, and androgen, on the contrary, is a male hormone. The male body produces both of these hormones. Normally, there should be more androgen. Estrogen serves as a relaxant for the male body, and androgen is involved in all functions that define a man by gender.

Testosterone is one of the most important hormones of the androgen group. It regulates a man’s behavior and his temperament. Androgen is responsible for the timbre of the voice, for example.

You can easily understand whether the male body produces enough androgens. Women understand this instinctively. If his voice is low, there is a lot of hair on his body, his strong-willed character means there are a lot of androgens.

If a man has a high-pitched voice, is emotional, has little hair, and has a mild temperament, his body produces more estrogen than normal.

Androgens perform an important function. Produced by the testicles and adrenal glands, they regulate the quantity and quality of sperm. The more androgens, the stronger a man's potency.

During different periods of a man’s life, the amount of these two hormones changes, but the ratio between them should remain within normal limits. If the ratio is violated, then they talk about hormonal imbalance.

Often hormonal imbalance occurs after 40 years of age. Clinically, there is even a name for this period - “male menopause.”

Starting from this period, the man’s body begins to produce significantly less androgens.

If during this period the ratio of estrogen and androgens is disturbed, then this becomes noticeable: the man begins to gain excess weight (even if he was not inclined to this before), his sexual desire subsides, problems with erection appear, and psychological problems arise against this background. The prostate gland is under attack. Failure of these hormones is the main cause of prostate adenoma.

Important! To find out the ratio of hormones in your body, it is enough to undergo an examination by taking tests for the hormones of interest, in this case it is androgen and estrogen.

Non-hormonal reasons

Hormonal factors can also be joined by non-hormonal causes of prostate adenoma, which aggravate the situation and increase the risk of developing the disease. It is from these factors that prostate adenoma most often occurs.

Prostate adenoma in a man can cause anxiety due to bad habits and a less active lifestyle.

  1. Drinking beer. Beer provokes the production of the hormone estrogen, which was mentioned above. If we talk about a pint of beer a couple of times a year, there’s nothing wrong with that. But, if a man is used to drinking beer almost every week, then the amount of estrogen in his body always increases. The balance is disrupted. If a man is over 30, then there is a big risk of getting a prostate adenoma as a “reward” for his beer exploits.
  2. Smoking. Smoking is always bad for health. But specifically for the prostate, this is an even greater evil. Each cigarette smoked causes a narrowing of small capillaries and vessels, which are rich in the male genitals. The quality of sperm, potency decreases, and then the risk of prostate hyperplasia increases.
  3. Nutrition. Spicy, salty and sweet foods, as well as sausages and fatty fried foods are all the wrong foods for the body. It leads to slagging, various gastrointestinal disorders and, therefore, the reproductive system also does not stand aside. Moreover, men who love fast food, fried cutlets with potatoes and similar foods feed their bodies with carcinogens, trans fats and force their bodies to work for wear and tear. Such food leaves nothing but problems with blood vessels, vitamin deficiencies and heaviness in the stomach.
  4. Cardiovascular diseases. Persistent high blood pressure, which is usually a consequence of a person’s lifestyle, constantly has a destructive effect on a man’s sexual function. This has been proven to increase the risk of prostate adenoma.
  5. Little physical activity. A sedentary lifestyle is contraindicated for humans by nature. This causes the skeleton to age faster, muscles atrophy from the age of 30, and stagnation occurs in metabolic processes. All this affects the prostate gland.
  6. Genetics. Genetic predisposition plays a small role, no matter how much people like to blame everything on it. Only 10% is given to the role of genetics. But family predisposition lies more in the transmission of lifestyle from father to son, which happens most often. If this can be called genetics, this is also the reason for the development of prostate adenoma.

Interesting! Race is a statistical factor leading to the development of prostate adenoma in men. Representatives of the Negroid race suffer from it more often, and Asians less often. But, rather, this is due to the specifics of their diet.

Concomitant diseases of the genitourinary system often lead to a further diagnosis of prostate adenoma. Extreme sports associated with sudden changes in temperature and hypothermia are indirect causes of prostate adenoma.

Conclusion

Video: about the prostate gland and adenoma.

By eliminating or correcting the causes of adenoma, which lie in lifestyle or hormones, you can avoid the disease. By undergoing the diagnosis of prostate adenoma, you can save yourself from unnecessary worries. Considering that this disease can be successfully treated, it is better not to start it.

Source: https://prostarenie.ru/bolezni/adenoma/prichiny-adenomy-prostaty.html

Prostate adenoma: causes of prostate cancer in men

Prostate adenoma is a disease accompanied by the proliferation of glandular or connective tissue of the prostate gland. The main symptom of the disease is disruption of the urination process as a result of compression of the urethra by pathological nodules.

The causes of prostate adenoma in men are most often associated with age-related changes reflected in hormonal levels. It is considered a benign neoplasm, but over time it can transform into prostatic cancer.

With a hereditary predisposition, the likelihood of an adenoma increases by 20%.

Characteristic features of the disease

Prostate adenoma (PAA) is a benign neoplasm located in the prostatic urethra. It compresses the urethra, causing discomfort. Statistics show that the disease most often develops after 40 years of age. It is during this period that the production of androgens in the male body decreases.

The nature of the manifestation of the disease depends on where the nodules are located and how quickly they grow.

At the initial stage of the disease, difficulties arise with urination. Over time, going to the toilet becomes more and more problematic. Stagnation of fluid in the bladder leads to infection. As a result, an inflammatory process develops and stones form.

The disease occurs in 3 stages. The first is called the compensation stage. It is characterized by discomfort when the bladder is completely emptied. The second stage is called subcompensation.

Prostate adenoma is a neoplasm that is benign in nature and is not capable of causing harm to the body.

It is distinguished by retention of a small amount of urine in the bladder. The third stage is accompanied by paradoxical ischuria and serious dysfunction of the urinary system.

PDA, unlike malignant neoplasms, does not pose a serious health hazard. But its complications affect the quality of intimate life and increase the risk of developing pathological processes. Therefore, it is important to diagnose and treat the disease in time.

Complications of adenoma include renal failure, various genitourinary pathologies, hematuria and acute urinary retention.

Reasons for development

The development of prostatic hyperplasia is associated with hormonal changes in the body. As you age, testosterone is not produced as intensely as before. This leads to a slowdown in metabolic processes. The situation is aggravated by a sedentary lifestyle, smoking and alcohol abuse.

The causes of prostate adenoma in men are as follows:

  • sedentary lifestyle;
  • arterial hypertension;
  • hereditary factor;
  • excess weight;
  • hormonal disorders;
  • age over 40 years;
  • poor nutrition.

In most cases, the appearance of an adenoma is preceded by a combination of various factors. If a man leads a healthy lifestyle and regularly visits doctors, he is much less likely to encounter prostate hyperplasia. A riotous lifestyle, unhealthy diet and excess weight contribute to the growth of pathological tumors even at a young age.

Age-related changes

According to statistics, 80% of men over 60 years of age suffer from prostate adenoma. The reasons for its appearance are changes in hormonal status. The process of semen production slows down with age. This is due to the cessation of testicular function due to a decrease in androgens and testosterone.

Sometimes prostate adenoma develops at a younger age. The causes of the disease are poor lifestyle and concomitant diseases.

With type 2 diabetes mellitus, hypertension and atherosclerosis, the structure of blood vessels is disrupted. This provokes stagnant processes in the pelvis, giving impetus to the appearance of adenoma.

Strengthening the body with the help of vitamin complexes and sports will help delay the process of reducing male hormones. If typical signs of sexually transmitted infections or an inflammatory process appear, you should consult a urologist. After 40 years, a man’s body is more susceptible to various diseases.

Hereditary predisposition

The likelihood of developing prostatic hyperplasia increases several times with a hereditary predisposition. If a man is in the risk category, he should pay special attention to his reproductive organs. Regular visits to the urologist and maintaining a healthy lifestyle will help prevent the development of pathology.

Diseases and disruptions in the endocrine system

The functioning of the thyroid gland has a direct impact on the production of hormones. With endocrine disorders, a hormonal imbalance occurs, which can provoke the growth of various tumors.

Compliance with the following rules helps prevent endocrine disorders:

  • increased physical activity;
  • rejection of bad habits;
  • normalization of sleep (at least 7 hours a day);
  • timely visit to the endocrinologist;
  • exclusion of stressful situations.

The severity of the symptoms of an endocrine disease depends on the degree of its neglect. With androgen deficiency, potency is primarily affected. On this basis, cardiovascular diseases, diabetes and nervous disorders develop.

When testosterone levels decrease in the body, the following symptoms appear:

  • fat deposits in the abdominal area;
  • decreased bone strength;
  • insufficient physical endurance;
  • muscle pain;
  • panic attacks;
  • changes in the condition of the skin, hair and nails.

Introducing foods high in iodine into the diet will help avoid the development of endocrine disorders.

Poor nutrition

Eating large amounts of fatty foods leads to increased cholesterol in the body. It has a destructive effect on the walls of blood vessels, provoking the appearance of atherosclerotic plaques. They slow down blood flow, contributing to the appearance of congestion in the genital area.

As a result, the risk of hyperplasia increases. To avoid this, you need to give up junk food. This includes carbonated drinks, fatty foods, sweets and smoked foods.

Advanced chronic prostatitis

Prostatitis is an inflammation of the prostate gland, occurring in acute or chronic form. It can be bacterial or non-bacterial. The main symptoms of the disease are intermittent urination, discomfort in the urethra and erectile dysfunction.

In the absence of timely treatment, it leads to infertility and impotence. Over a long period of time, chronic prostatitis can transform into an adenoma.

To detect the disease in time, it is enough to undergo preventive examinations with a urologist.

Prostatitis is treated in a comprehensive way. Drug therapy involves taking anti-inflammatory drugs, antispasmodics and drugs that normalize circulatory function. Prostate massage and lifestyle changes can help increase your chances of recovery. It is necessary to follow the basics of proper nutrition and exercise.

Read also:  Symptoms of impotence and ways to diagnose erection problems

Race

The causes of prostate adenoma in men may also relate to race. This is due to the individual characteristics of the body and the influence of climate. It is known that representatives of the Negroid race encounter adenoma more often than others.

They have a 47% chance of developing the disease. Europeans are less likely to develop formations in the prostate gland. Asians hardly encounter it.

If you ignore the first manifestations of prostate adenoma, the tumor grows, squeezing the urinary canal.

This is explained by the peculiarities of their diet. They eat foods high in phytosterols, which prevent the formation of benign tumors.

Hormonal factors in the development of the disease

The process of maturation of seminal fluid and the functioning of the organs of the reproductive system are carried out under the influence of hormones. Androgen production occurs in the adrenal glands and testes. If the functioning of these organs is disrupted, the level of hormones decreases, which affects external sexual characteristics and provokes various pathologies.

People experience hormonal imbalances during adolescence or after 50 years. In the first case, the process of puberty is influenced by external factors and genetic abnormalities.

In adulthood, the problem is caused by natural physiological processes. In both cases, it is necessary to take hormonal medications. It is selected after passing a test that reveals which hormones are missing.

In some cases, dietary supplements of plant origin are prescribed to stimulate the production of one’s own hormones. Such drugs include Alphabet vitamins for men, Panthea drops, Viardot and Selzinc plus. It is also important to enrich the diet with foods containing useful substances: zinc, selenium, retinol, manganese, calcium and iodine.

Hormonal medications should not be taken without consulting a doctor. This could lead to a worsening of the current situation.

Before starting treatment, it is important to determine why the adenoma appeared. In the future, this will allow measures to be taken to prevent relapse. Doctors recommend that men who have coped with prostate hyperplasia undergo preventive examinations more often than usual. With the right approach, the disease will not leave its mark on reproductive health.

Source: https://potenciya.guru/prostatit/adenoma-prostaty/prichiny-adenomy-prostaty/

Causes of prostate adenoma

Benign prostatic hyperplasia (BPH), or prostate adenoma, is one of the most common diseases of men after 40 years of age. According to statistics, every third man aged 40-49 years experiences symptoms of adenoma, and by the age of 60 years their number reaches 67% [1].

The causes of prostate adenoma are still not fully understood.

Some scientists and doctors believe that prostate hyperplasia is one of the manifestations of age-related androgen deficiency - a condition that occurs in a man in adulthood, when, against the background of a decrease in testosterone levels, characteristic clinical symptoms begin to appear (sexual dysfunction, psycho-emotional and somatic disorders).

To understand whether these problems can be avoided, you need to understand what causes the disease.

The prostate is a small, unpaired organ located in the pelvic cavity just below the bladder and in front of the rectum. It consists of smooth muscle and secreting cells and performs important functions:

  • is a valve that prevents the flow of urine during ejaculation and seminal fluid during urination,
  • performs the work of an additional sphincter,
  • produces seminal fluid components: antibodies, enzymes, vitamins[2].

Prostate secretion dilutes the ejaculate, activates the movement of sperm and protects them from the aggressive environment of the vagina.

An important feature of the prostate is that its size changes throughout life. As a child she is small. Its active growth and development begins during puberty, when the body begins to produce sex hormones. In old age, when the secretion of hormones begins to decline, the prostate undergoes involution - reverse development [3].

“Adenoma” in Latin is a growth of secreting tissue. With benign prostatic hyperplasia, dense nodules form from the paraurethral glands of the prostate3. In itself, this growth is painless and almost never degenerates into malignant tumors.

However, over time, the nodules enlarge and begin to block the urethra or cause smooth muscle spasms. This process is accompanied by urination disorders: a painful, strong urge to urinate appears, urine flows in a thin intermittent stream or drops, trips to the toilet become more frequent, especially at night, ejaculation becomes painful.

These symptoms are the reason to consult a doctor3.

According to the degree of severity, benign prostatic hyperplasia of the first, second and third degrees is distinguished. In the initial stages, the disease can be stopped and symptoms can be managed with medication. At subsequent stages, surgery is indicated[4].

The causes of prostate adenoma have long been of concern to urologists. Doctors are now confident that BPH is a multifactorial disease, and several causes play a role in its occurrence[5]. Let's look at some of them.

Is dihydrotestosterone to blame?

Back in the 19th century, doctors found out that the cause of prostate adenoma in older men is a violation of hormone secretion[6]. An increase in the amount of estrogens and a decrease in the amount of androgens (testosterone and dihydrotestosterone) lead to an imbalance in the physiological balance between hormones, which ultimately contributes to disruption of the control of prostate cell growth and function.

The level of sex hormones in the blood is regulated by the hormones of the hypothalamus and pituitary gland.

In prostate cells, testosterone is transformed by the enzyme 5a-reductase into dihydrotestosterone. This compound promotes the growth of prostate secreting cells, that is, their hypertrophy[7].

In youth, free testosterone inhibits the synthesis of dihydrotestosterone and maintains a healthy balance that prevents excessive growth of glandular tissue. With age, this type of regulation fails.

The treatment of BPH with drugs that block 5a-reductase is based on blocking this mechanism [8].

Interestingly, prostate adenoma does not develop in men who had their testicles removed in early childhood, before puberty. This confirms the hormonal theory of the development of BPH.

Estrogen component

Between 40 and 50 years, a man’s body undergoes profound hormonal changes. During this period, the secretion of testosterone decreases and the concentration of estradiol (female sex hormone) in the blood increases [9].

An increase in estrogen levels causes the production of specific growth factors and stimulates the replacement of smooth muscle cells in the prostate with connective tissue. Because of this, the coordination of smooth muscles and the bladder is disrupted, that is, the obturator mechanism of the prostate suffers [10].

With a biopsy of prostate tissue, it is clearly visible which parts of the gland have undergone greater hyperplasia: secreting or connective tissue[11].

Genetic theory

Recently, much attention has been paid to the theory of changes in the genetic information of prostate cells. This results in stimulating the growth of prostate tissue and/or increasing its sensitivity to hormones.

Great importance is also attached to risk factors contributing to the development of prostatic hyperplasia. Such risk factors include, first of all, a hereditary factor (family history).

It has been repeatedly proven that men whose fathers suffered from prostate adenoma are at risk of developing benign hyperplasia much more often than those whose fathers did not have such problems with the prostate gland.

Some scientists highlight the national characteristics of the patient as the cause of prostate adenoma - for example, this pathology is less common in Asians than in black and white men. The issue of overweight and obesity is being discussed in the scientific world. If your body mass index exceeds 24 kg/m2, you should think about adjusting your diet and consult a nutritionist.

Metabolic disorders

In 2015, a study was released that linked metabolic syndrome and benign prostatic hyperplasia [12].

According to the collected materials, in addition to testosterone deficiency, the progression of BPH is influenced by:

  • deficiency of vitamins B and D[13],
  • increasing insulin resistance and type 2 diabetes mellitus[14],
  • obesity,
  • metabolic syndrome,
  • arterial hypertension,
  • lipid imbalance,
  • oxidative stress,
  • metabolic neuropathy[15].

This theory suggests that for effective treatment of prostate adenoma, it is necessary to prescribe individual treatment and combine it with lifestyle correction.

The first preventive measure is an annual visit to a urologist or andrologist after 40 years. At the appointment, the doctor will be able to assess the size of the gland and perform a transrectal ultrasound to determine the degree of hypertrophy[16].

It is unlikely that lifestyle changes will influence dihydrotestosterone and estradiol levels[17]. But the metabolic theory gives great scope for preventive measures. These include:

  • body weight control (no overeating),
  • reducing stress levels, timely treatment of depression[18],
  • active lifestyle: play sports, spend more time in the fresh air,
  • increasing the proportion of ballast substances in the diet,
  • control of blood glucose levels,
  • reducing the amount of refined carbohydrates in food,
  • replenishment of deficiency of vitamins B, D and polyunsaturated fatty acids,
  • limiting the consumption of red meat[19].

Scientists were unable to find a connection between sexual activity, smoking, alcohol abuse, sexually transmitted infections, and the development of prostate adenoma. But the quality of life is better for those men who try to lead a healthy lifestyle, play sports, and prefer healthy foods (mainly consisting of plant foods and fiber).

However, even if all these rules are followed, not a single man in the world is immune from the development of prostate adenoma.

[1] Joseph C. Presti, Jr. MD Benign Prostatic Hyperplasia Inc., Epidemiology. //Eur. Urol. (suppl 4), 2001. 43-47.

[2] Diseases of the prostate gland / ed. SOUTH. Alyaeva. M.: GEOTAR-Media, 2009.

[3] Lopatkin N.A. (ed.). Benign prostatic hyperplasia. M., 1999.

[4] Lopatkin N.A. About complications of prostate adenomectomy and methods of their treatment. Urology and Nephrology 1982; (1): 3-9.

[5] Gacci M., Corona G., Vignozzi L., Salvi M. [et al.]. Metabolic syndrome and benign prostatic enlargement: a systematic review and meta-analysis // BJU Int. 2015. Vol. 115, No. 1. P. 24-31.

[6] Schroder FH, Altwein JE. Development of benign prostatic hyperplasia. In: Benign Prostatic Hyperplasia. A diagnosis and treatment primer. Oxford, 1992; 31-50

[7] Chawnshang C. Androgens and androgen receptor: mechanisms, functions, and clinical applications. USA: Kluwer Academic Publishers, 2002. 503 p.

[8] Ansari MA, Begum D., Islam F. Serum sex steroids, gonadotrophins and sex hormonebinding globulin in prostatic hyperplasia // Ann. Saudi. Med. 2008. Vol. 28. P. 174-178.

[9] Tkachuk V.N., Al-Shukri S.H., Kornienko V.I., Lukyanov A.E. Drug treatment of patients with benign prostatic hyperplasia. St. Petersburg, 2000; 104.

[10] Pytel Yu.A. Drug therapy for prostate hyperplasia. All-Russian Plenum. Society of Urologists: Abstracts of reports. Saratov, 1994: 5-19.

>[11] Marberger M. Evolution in the understanding of BPH: Disease Progression. Changing Perspectives on Prostate Disease: Abstracts. Rome, 2001:6

[12] Gacci M., Corona G., Vignozzi L., Salvi M. [et al.]. Metabolic syndrome and benign prostatic enlargement: a systematic review and meta-analysis // BJU Int. 2015. Vol. 115, No. 1. P. 24-31.

[13] Espinosa G., Esposito R., Kazzazi A., Djavan B. Vitamin D and benign prostatic hyperplasia - a review // Can. J. Urol. 2013. Vol. 20, No. 4. P. 6820-6825.

Read also:  HPV infection in women: diagnosis with symptoms and treatment

[14] Khan ZA, Chakrabarti S. Endothelins in chronic diabetic complications // Can. J. Physiol. Pharmacol. 2003. Vol. 81. P. 622-634.

Source: https://uro-info.ru/adenoma/causes/prichiny-vozniknoveniya-adenomy-prostaty/

Causes of prostate adenoma in men: why the disease occurs

  • Urologist-andrologist 1st category Petr Viktorovich
  • 26350
  • Update date: December 2019

Prostate adenoma is the most common disease of the male genitourinary system in older age.

If prostate adenoma is diagnosed, the causes should be sought in male physiology itself, since the disease is caused by hormonal changes.

The pathology progresses slowly, but is difficult to treat, so it is important to promptly recognize the symptoms and consult a urologist.

What is prostate adenoma?

The disease is more common in older men

The disease is a benign growth (tumor) of the glandular tissue of an organ. The official name of the disease is benign prostatic hyperplasia or BPH.

The pathology is diagnosed in men over 60 years of age. In general, an adenoma cannot be called a disease, since its development is determined by the physiological characteristics of the male body. However, this disorder causes a lot of painful symptoms that can worsen a man’s life.

Adenoma is difficult to treat. Drug therapy is effective only in the initial stages of the disease. In advanced cases, surgery is necessary, but it does not guarantee complete removal of the tumor. This is due to the fact that surgery cannot stop the pathological process of epithelial proliferation, so after a few years the pathology can make itself felt again.

Mechanism of adenoma development

To understand why men develop prostate adenoma and how it progresses, you should know the specifics of the development of this organ.

The prostate gland is a hormone-dependent organ; its work is directly related to the activity of testosterone. In boys, before puberty, the organ is very small.

As you get older, your prostate gland also grows. The process of human growth is completed by approximately 18-20 years, and the prostate gland does not change in size for several decades.

This is due to the stable production of sex hormones.

As men age, they experience what is called andropause. During this period, the synthesis of the main sex hormone decreases. The body needs testosterone less, but its production does not stop completely. As a result, the hormone ceases to be fully consumed.

Under the influence of a number of enzymes, testosterone in the body breaks down into dihydrotestosterone. This substance is absorbed by the prostate tissue. Due to a decrease in the body's need for sex hormone, its excess is taken over by the prostate and gradually increases in size.

The tissues of the organ grow, fluid is retained in them under the influence of testosterone, a tumor gradually forms, and the organ becomes larger.

These changes happen very slowly. For many years, the disease does not make itself felt, but when the enlarged organ begins to put pressure on nearby tissues, the first symptoms of pathology appear.

Course of the disease

The appearance of adenoma in men is preceded by many years of asymptomatic changes in the tissues of the prostate gland. The first signs appear on average 5 years after the onset of the pathological process. There are three stages of the disease:

  1. In the first stage, the organ enlarges and puts pressure on the urethra and bladder. This is accompanied by mild dysuric disorders - there is a more frequent need to visit the restroom, and at night you feel a constant filling of the bladder.
  2. In the second stage, the disease takes on a more severe form. The bladder gradually stretches, and the lumen of the urethra narrows. Frequent urge to go to the toilet is aggravated by the need to strain the pelvic muscles to empty the bladder. At the same time, the stream of urine is weak, and the man cannot fully control it.
  3. At the third stage, due to severe distension of the bladder, a problem such as incontinence arises. Every trip to the restroom becomes a real test: a man strains for a long time to start urinating, strains his muscles very hard to hold back the stream of urine. At the end of the process, urine continues to leave the bladder, which is manifested by slight leakage. Empirical urge to go to the toilet and urinary incontinence are possible.

The third stage of the disease is dangerous due to the development of complications. Due to compression of the urethra, it may become pathologically narrowed (urethral stricture). This leads to urinary retention.

This is a dangerous complication that requires medical attention. Against this background, inflammation of the bladder (cystitis), nephritis, and urolithiasis may develop.

As a rule, at the third stage of BPH there is a need to constantly wear urological pads or a urine bag.

Symptoms

Source: https://muzhik.guru/bolezni/adenoma-prostaty/adenoma-prostaty-prichiny/

Prostatitis: causes, diagnostic methods

General information

According to WHO statistics, 60-75% of men of reproductive age face the problem of prostatitis. In Russia, the disease is diagnosed in one third of men who apply, thirty percent of whom are under 40 years of age. Every tenth man on the planet has encountered prostatitis in his life.

Features of the course of the disease

The clinical picture of prostatitis in men is varied, depending on the individual characteristics of the body, general health, and lifestyle.
In men 35–40 years old, prostatitis is asymptomatic. Its first signs make themselves felt almost a year later. In medicine, it is customary to distinguish 2 forms of the disease:

  • infectious;
  • stagnant (non-infectious).

In the first case, the infection is localized in the pelvic organs, in the second, in the prostate area, blood circulation is hampered and the functioning of the gland is disrupted.

Factors influencing the development of the inflammatory process

Inflammation is characterized by acute and chronic course. The acute form of the disease is accompanied by high fever, pain in the lower back and sacrum, and discomfort in the reproductive organs. Acute prostatitis begins suddenly. Its appearance is provoked by genitourinary infections:

  • cystitis;
  • pyelonephritis;
  • urethritis;
  • STI.

Pseudomonas aeruginosa and Escherichia coli are the main pathogens that provoke the occurrence of the disease.

Inflammation of the prostate in young men: causes and consequences

The disease first makes itself felt at 30-40 years of age. The cause of prostatitis can be Trichomonas, chlamydia, ureaplasma - the causative agents of prostatitis that provoke its occurrence.

Contacting a specialist is a difficult step. Young people are embarrassed by their problems, put off going to the doctor, and thereby aggravate the situation.

The infection spreads quickly, which accelerates the onset of inflammation of the prostate.

Consequences of untimely treatment of the prostate in young men:

  1. urinary function is impaired:
  2. problems with potency appear;
  3. reproductive function is suppressed;
  4. relapses of prostatitis become more frequent;
  5. calcifications and scars appear.

The appearance of the first symptoms of inflammation of the prostate gland should be a signal to consult a doctor.
A person should pay attention to his health if the following signs occur:

  • the desire to urinate appears more often;
  • discomfort and pain are felt during urination;
  • after going to the toilet the desire to urinate does not go away;
  • erection weakens or disappears;
  • attraction to a partner decreases.

Ignoring the signs leads to advanced prostatitis in men becoming chronic. The production of prostatic secretion, which is part of sperm, is reduced.

Causes of prostatitis in men

It is believed that prostatitis occurs due to infections.

  1. Infectious route. The main causes of prostatitis lie in the proliferation of microorganisms that are introduced into the blood and spread throughout the body with its current. This is how primary infection occurs. Secondary occurs when the inflammation process was not noticed in time and spread. Pathological processes occur in the urinary canal that provoke the appearance of prostatitis, the cause of which is intestinal diseases of the organs of the reproductive system. Infection occurs in two ways. The ascending pathway occurs when the infection enters the prostate from the opening of the urinary canal. The descending pathway occurs when infected urine is the source of infection.
  2. Weak immune system. Irregular sleep-wake cycle, poor nutrition, addiction to drinking alcohol and smoking, chronic stress are sources of decreased immunity. He is unable to resist infectious agents.
  3. Impaired blood circulation. Depressed blood circulation as the cause of the disease is a consequence of physical inactivity, poor heart function, and diseases of the nervous system. Blood in the pelvic organs begins to circulate poorly. The result is oxygen starvation and inflammation of the prostate gland.
  4. Lack of regular intimate life and unprotected sex as causes of prostatitis. Inflammation can occur as a result of a lack or excess of intimate life. Young men who lead overly active lives suffer from rapid loss of potency, hormonal imbalance and glandular secretion. Interrupted sexual intercourse is a factor that adversely affects a man’s health.
  5. Prostate injuries resulting from vibration disease. Drivers often suffer from prostate dysfunction as a result of constant vibration. This is a common cause of prostatitis in men.
  6. Alcohol and cigarette abuse are the causes of prostatitis. It has been scientifically proven that systematic drinking leads to swelling of prostate tissue. If the immune barrier is weak, favorable conditions arise for the penetration of microorganisms.
  7. Nutritional features: Foods treated with chemicals can provoke the occurrence of malignant neoplasms. Prostate cancer is one of the leading causes of death among men over 50 years of age.
  8. Phimosis is the cause of the development of the inflammatory process. This is a disease that is characterized by incomplete opening of the head of the penis. Phimosis often occurs in newborns. In this case, phimosis is a congenital defect. If treated promptly, it disappears after a couple of months. For an adult man, phimosis is a serious problem, not only physical, but also psychological. If the head of the penis is completely closed, fluid accumulates under it, which is a favorable environment for the growth of bacteria. Pathogenic microbes cause prostatitis. Treatment of phimosis in adulthood involves surgery.
  9. The presence of stones in the prostate gland is a prerequisite for inflammation.
  10. Occupational diseases.
  11. The pathological structure of the prostatic gland can cause inflammation, since prostatic secretions stagnate in the urinary canal.
  12. Hormonal disorders. Low hormone levels affect sexual desire. Lack of sex for a long time can lead to the formation of venous stagnation.

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Types and symptoms of the disease

Chronic prostatitis in advanced stages can develop into sepsis.
The following symptoms are characteristic of acute prostatitis:

  • fever;
  • urinary retention;
  • Whitish discharge begins to appear in the urine.

Chronic prostatitis is a recurrent form of the disease. An inflammatory focus is a place where microbes multiply, settle in the genitourinary tract and infect tissues.

The consequence of untimely consultation with a doctor is chronic cystitis.
Nine out of ten cases of chronic prostatitis are the reason for a visit to the doctor.

The reasons for men are the same: pathogens of an infectious nature.

Chronic asymptomatic prostatitis: causes in mature men

The described chronic prostatitis does not belong to any of the listed groups. The cause of occurrence is the physiological features that occur in older men.

The patient does not complain about the severity of symptoms. A person only learns about the presence of the disease through tests or surgery.

It is less often diagnosed in patients whose age has exceeded the mark of forty years.
Causes of chronic prostatitis:

  • infections;
  • pathogenic microbes.

Chronic prostatitis, which is caused by an infection, is very difficult to treat with medication.
Congestive prostatitis occurs in young people due to irregular sex life, when the gland is most active. No reliable reasons for its appearance have been identified.

Signs that distinguish congestive prostatitis:

  • weakening of sexual desire;
  • lack of vivid orgiastic sensations;
  • weak erection;
  • the desire to urinate is especially pronounced in the morning;
  • Difficulty urinating is almost invisible.

The causes of prostatitis are still not fully understood. It is known that men who have somatic diseases more often suffer from the inflammatory process:

  • intestinal diseases, stool disorders;
  • chronic bronchitis, ARVI;
  • the presence of lesions in other organs (caries, tonsillitis);
  • previous STDs;
  • immune pathologies.
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Pathogenic microorganisms penetrate tissues and form stagnation.
What are the causes of infectious diseases of the prostate gland? Factors that contribute to the spread of infection are:

  • completeness;
  • systematic drunkenness;
  • smoking;
  • uncomfortable, tight clothing;
  • prolonged exposure to the cold;
  • frequent car trips.

Treatment of prostatitis: features of therapy

Therapy for prostatitis is prescribed by a doctor based on the form and characteristics of the disease. The causes of prostatitis in men are taken into account. In case of acute prostatitis, the patient is prescribed antibiotics that can penetrate the tissues of the diseased organ. Chronic prostatitis is treated comprehensively and includes a course of medications, immunomodulators, prostate massage, and physiotherapy.

Non-bacterial chronic prostatitis is treated with a course of non-steroidal drugs. Additionally, medications with sedative properties are prescribed.

The prostate may begin to change if the disease becomes severe. An abscess, urination disorder, prostate sclerosis, and extensive swelling occur.

The causes of prostate adenoma lie in untimely contact with a specialist. Regular visits to the urologist for preventive purposes will help protect yourself. The disease affects more and more young men. At 30 years of age, the disease is easier to prevent than to treat. The rules of prevention consist in eliminating destructive factors.

A man who cares about his health should lead a healthy lifestyle, play sports, wear comfortable underwear made from natural fabrics, avoid exposure to excessively low and high temperatures, and monitor his diet. Regular sex life is a prerequisite for maintaining men's health.

Knowing the causes of prostatitis and following simple rules, a person can maintain reproductive health for many years.

Source: https://mzdorov.com/andrologia/bolezni-prostati/glavnye-prichiny-vozniknoveniya-prostatita-u-muzhchin.html

BPH

Speaking about men's health, as well as the pathologies that undermine it, it is important to highlight the most common one - prostate adenoma (prostate adenoma). There is another, new name for this disease - benign prostatic hyperplasia (BPH).

Prostate adenoma in men, or BPH: what is the point?

The prostate gland is located in the pelvic area downward from the bladder.

It affects the ejaculatory ducts and urethra, has an elastic consistency and consists of glandular and muscle cells.

The important functions of this gland are the production of secretion to ensure the life of sperm, the creation of normal hormonal levels, and blocking the elements of the bladder at the time of ejaculation.

With the development of prostatic hyperplasia, benign tumor-like formations form in the prostate, which, as they grow, increasingly put pressure on the urethra, making it difficult for the normal passage of urine.

Benign prostatic hyperplasia (BPH) also disrupts a man’s sexual function - the time of sexual intercourse is reduced, and a feeling of discomfort and pain appears during ejaculation.

With prostate adenoma, the gland stops secreting. It is filled with fibromuscular tissue. This is a type of connective tissue that has relatively high tensile strength. It consists of collagen and elastic fibers.

One of the main factors in the development of the disease is age. Often, prostate adenoma affects men whose age exceeds 40 years.

How do the symptoms manifest and what are the signs of prostate adenoma?

The manifestation of signs of prostate adenoma in men occurs in stages. The development of the disease is quite slow, and if the fibrous neoplasm is localized far from the urethra, its first stages develop asymptomatically. Further, as it develops, it will no longer be possible to ignore the disease.

Symptoms of prostate adenoma, or prostatic hyperplasia (BPH) in men are:

  • Significant increase in the number of urges to urinate at night (up to 8 times).
  • Urgent and sudden urge to urinate during the day.
  • Difficulty passing urine.
  • Low-intensity stream of urine.
  • When the bladder is full, urine is released drop by drop.
  • After urinating, there is no feeling of emptying the bladder, the desire to go to the toilet still remains.
  • Problems with erection.
  • Pain in the groin, radiating to the testicular area.

A man should seek medical help when he detects the first, even mild, signs of prostate adenoma.

Causes of prostate adenoma in men

The main cause and factor provoking the occurrence of prostate adenoma is age.

According to research, benign prostatic hyperplasia (BPH) occurs in approximately 50% of men after forty years of age.

At the same time, of course, it cannot be said that pathology occurs in absolutely all men after this age. There are other causes of this disease, which together affect men’s health:

  • Genetic predisposition.
  • Inflammatory processes of the genital organs of a chronic form. Inflammations of an acute form can progress to the chronic stage, for which the necessary treatment was not prescribed (or the patient himself did not pay attention to his health, did not consult a doctor).
  • Incorrect, unbalanced diet.
  • Hormonal imbalance.
  • Atherosclerosis and arterial hypertension.
  • Diabetes.
  • Excess body weight.
  • Passive lifestyle, inactivity.

Causes of prostate adenoma can also be a man’s bad habits – alcoholism, smoking.

As can be seen from such a long list of reasons, some of them do not depend on the man (for example, heredity). But some risk factors can be prevented by monitoring your health, diet and lifestyle.

Types and stages of development

Prostatic hyperplasia is divided into types in diagnosis:

  • Glandular – in the structure of the prostate the number of glandular elements increases.
  • Fibrous - formed from connective and glandular tissue. It takes a lot of time to grow. Despite its benign quality, if left untreated for a long time, it can develop into cancer.
  • Muscular – formed as a result of the growth of smooth muscle tissue of the prostate gland.
  • Mixed.

According to the type of localization, the disease is divided into forms:

  • Intravesical - the tumor partially extends into the cavity of the bladder.
  • Prevesical - the lateral parts of the prostate adjacent to the bladder expand.
  • Subvesical - the tumor is directed towards the intestine.

The disease develops gradually, slowly moving from one stage to another.

1st degree . The disease has mild symptoms and is expressed in a slight change in the dynamics of urine outflow, frequent urination at night, and a somewhat prolonged outflow of urine during the day.

Perhaps the pathology will affect erectile function, but many men tend to attribute this symptom to fatigue and stress rather than to problems with their health.

Often, first-degree prostate adenoma can be confused with similar diseases, such as cystitis and nephritis.

2nd degree . A man wakes up at night with the urge to urinate, but cannot easily empty his bladder (there is always residual urine in it). The desire to urinate does not disappear.

3rd degree . At this stage, in addition to all the symptoms described above, pain is added, which appears both during urination and during ejaculation. Pain in the abdominal area can bother a man even at rest. It becomes very difficult to empty your bladder.

Always filled, it stretches, its walls lose sensitivity, and the muscles stop contracting. Constant discomfort makes a man irritable, his sleep and appetite are disturbed, weakness and chronic thirst appear.

In other words, normal life activity and performance are almost completely disrupted.

Consequences and complications of prostate adenoma in men

The consequences of an untreated adenoma are as follows::

  • Kidney dysfunction.
  • Inflammatory diseases of the urinary tract.
  • Urolithiasis (or urolithiasis).
  • Varicose veins of the bladder neck.
  • Impotence.

The complications mentioned above leave no doubt as to whether prostate adenoma is dangerous for men. Definitely yes.

Diagnosis of prostate adenoma: what procedures does a doctor prescribe to examine a man’s prostate gland?

Diagnosis of BPH begins with palpation of the prostate gland, which allows the doctor to draw conclusions about the size of the prostate itself and the approximate volume of benign hyperplasia. Next, to diagnose prostate adenoma, ultrasound or TPUS (or both procedures) is prescribed. TPUS is a more informative examination and is performed transrectally.

In case of prostate adenoma, the patient is also prescribed a referral for a blood test, which will show the number of antigens present in it.

In order to make sure that it is a benign tumor and not cancer, the patient is prescribed a biopsy of adenoma (hyperplasia nodes) of the prostate gland. Next, the biological material is transferred to the laboratory for microscopic examination for the presence of atypical cells.

These diagnostic procedures can be performed at any stage of development of prostate adenoma.

Modern treatment of prostate adenoma in men: methods for eliminating BPH

Is prostate adenoma treated without surgery? Yes, but only if the patient paid attention to problems in his health in the early stages of the disease.

Treatment at stages 1 and 2 of the formation of prostate adenoma can be carried out using medications, prostate massage and other non-invasive techniques. This treatment will be most effective if the patient combines it with diet, special exercises and giving up bad habits.

Treatment of prostate adenoma at a late stage of development of hyperplasia will most likely involve minimally invasive or surgical methods: cryotherapy, ultrasound therapy, embolization of prostate arteries, balloon dilatation, and so on.

Elimination of the disease: laser vaporization of prostate adenoma as one of the advanced methods of treating the prostate gland in men

The most famous of the relatively harmless methods of surgical treatment of prostate hyperplasia (BPH) is the operation of laser vaporization of the resulting prostate adenoma. It is carried out without incisions, using endoscopic equipment inserted through the urethra. This operation is effective for adenomas whose volume does not exceed 80 ml.

During the operation, a special laser system is used. It produces rays of a certain length. Vaporization (or, more simply, evaporation) is carried out using a flexible light guide, at the end of which there is a small device. During vaporization, selective tissue removal and cauterization of blood vessels are performed to prevent the possibility of bleeding.

Many patients are concerned about the question: how to treat benign prostatic hyperplasia if a lot of time has been lost and the disease is in its last stage?

If prostate hyperplasia is too advanced, doctors may prescribe another surgical operation - laser enucleation (or removal) of a prostate adenoma of any size.

One of the types of laser enucleation is transurethral resection of prostate adenoma (TURP of prostate adenoma).

The tumor is removed in pieces that were previously separated (cut out) from the total mass of the tumor using a laser.

The choice of a specific type of laser surgery to remove prostate adenoma - vaporization or TUR - depends on the severity of the disease, the general condition of the patient, the presence of other diseases and other factors.

Consequences and rehabilitation of the patient after surgery to remove prostate adenoma

The postoperative period after surgery to remove prostate adenoma can last 2–4 weeks. The consequences may be as follows:

  • Blood loss.
  • Infection.
  • Heart failure (due to anesthesia).
  • Blood in urine.
  • Urinary incontinence.

Prevention of prostate adenoma in men

To prevent adenoma, it is important to take care of your health, and it is better to start from a young age.

You should adhere to a healthy, balanced diet (eat foods rich in zinc), eliminate alcohol and tobacco, lead an active lifestyle and establish a regular sex life (preferably with one partner - in addition to prostate adenoma, this will help avoid many other health problems).

Reducing the likelihood of prostate adenoma in men is not as difficult as it seems - all the preventive measures listed above should become a way of life and be taken for granted.

Source: https://mcgenesis.ru/services/urologia/adenoma-predstatelnoy-zhelezy

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