Why do blood pressure pills cause coughing, is it dangerous? It should be said that hypertension is a serious pathological condition that requires long-term complex therapy, since surges in blood pressure negatively affect the performance of the kidneys, blood vessels and heart. For this purpose, medications of various groups are prescribed, some of them can provoke such a negative symptom as cough syndrome.
Let's look at what medications help cough, what to do if it occurs, how dangerous it is, and what medications are available that do not have such a negative effect.
Causes of cough during drug treatment of hypertension
Coughing when taking blood pressure pills is one of the adverse reactions of some antihypertensive drugs. This symptom is observed relatively often, but not in all patients.
According to doctors, cough syndrome, as a complication after taking antihypertensive drugs, is diagnosed in 15% of hypertensive patients, while in patients with long-term heart diseases this figure is much higher and amounts to 26%.
The reason for the manifestation of a dry cough, as a complicated consequence of the use of medications for manifestations of hypertension, is explained by:
- Undergoing treatment with ACE inhibitors.
- Use of drugs from the beta-blocker group.
- A cough can also be caused by the excessive presence of the peptide bradykinin in the body, which can linger in the upper parts of the respiratory system.
- Often, painful coughing from taking pills occurs in patients who have a genetic predisposition to such an anomaly. With this clinic, inflammation occurs in the back of the pharynx, which provokes a cough.
You should know that modern medications for high blood pressure are classified according to their medicinal characteristics.
Type of drugs | Main characteristics | Name |
Diuretics are divided into the following types: loop, thiazide, potassium-sparing. |
They lower blood pressure by removing excess fluid and salt from tissues. | Furosemide. Indapamide. Hydrochlorothiazide. |
Calcium antagonists | Stops the penetration of calcium into muscle tissue cells. When calcium levels are low, muscles are unable to contract, which causes the arteries to dilate. | Diltiazem. Verapramil. Amlodipine. |
Adrenergic blockers There are two types: alpha-blockers and beta-blockers. |
They help lower blood pressure by blocking hormone receptors such as adrenaline and norepinephrine. | Alfuzosin. Metoprolol. Atenolol. Bisoprolol. |
Angiotensin receptor blockers | The therapeutic effect is similar to ACE inhibitors, but the drug effect is much longer and stronger. | Moxonidine. Losartan. Cardosal. |
ACE inhibitors | They reduce the synthesis of renin, thereby achieving a vasodilating effect and reducing the load on the heart muscle. They normalize blood pressure in diabetes mellitus. | Ramipril. Captopril. Enarapril. |
Neurotropic | Calms the central nervous system when hypertension is caused by prolonged stress. | Physiotens. Moxogamma. Rilmenidine. |
Typically, when treating hypertension, cardiologists prescribe at least two drugs, which minimizes possible harm from the dosage, thereby preventing possible side symptoms.
Symptoms of medication cough
- Dryness.
- Curtness.
- Long presence.
- Periods of exacerbation.
In addition, after taking medications for blood pressure, the cough reflex may become stronger in the morning, during lying down, body movement and physical stress.
A prolonged cough can lead to other associated symptoms:
- Hoarseness.
- Vomit.
- Decreased appetite.
- Urinary incontinence.
It should be emphasized that with a medicated cough there are no signs of renal failure, allergic manifestations or bronchial obstruction.
Although it is not contagious to other people, it causes unpleasant discomfort to hypertensive patients and can cause depression, so it must be cured.
What medications provoke the syndrome?
Types of medicines | Names of drugs as an example |
Beta blockers | Bisoprolol. Nebivolol. Atenolol. |
Angiotensin receptor blockers | Eprosartan. Valsartan. Cardosal. Telmisartan. Losartan. |
ACE inhibitors | Elanapril. Ramipril. Captopril. Perindopril. |
As experts note, a strong cough reflex is most often stimulated by medications that belong to the enalapril class of ACE inhibitors.
What medications do not help cough?
Many hypertensive patients who have had to deal with medicinal cough are interested in what alternative medications are available that do not contribute to its development.
In this situation, cardiologists advise taking medications that do not cause a dry cough:
- Calcium antagonists.
- Diuretics.
- Combined impact.
Let us consider in more detail the medicinal properties of drugs from these groups.
Calcium antagonists
- They have a minimal list of possible side effects.
- Significantly improve the well-being of a person with hypertension.
- Suppresses excessive excitability.
- Increases the activity of heart contractions.
- Steadily normalize hypertensive blood pressure levels.
- They are well tolerated, including by elderly patients.
- Have a beneficial effect on the kidneys.
- Stabilizes the metabolic processes of carbohydrates.
- Improves oxygen supply to cardiac tissues.
- They do not have the ability to provoke depression.
- They have absolutely no effect on the tone of the bronchi.
- Prevents excessive activity of the left ventricle.
- Reduce the risk of coronary artery disease.
Among calcium antagonists that are not capable of causing cough syndrome, the following should be noted:
- Riodipine.
- Isradipin.
- Nicardipine.
- Lacidipine.
- Nimodipine.
- Riodipine.
- Felodipine.
- Nitrendipine.
- Amlodipine.
Despite their positive medicinal aspects, it is necessary to check with your doctor about their dosage and other nuances of taking them.
Diuretic medications
- Excess fluid is quickly removed.
- Relieves symptoms of edema.
- They do not provoke a cough.
- Prevents the accumulation of phlegm in the lungs.
Among the diuretics prescribed for hypertension, which are not capable of causing cough, it should be noted:
- Furosemide.
- Diuver.
- Arifon.
- Triampur.
- Spironolactone.
- Veroshpiron.
- Indapamide.
- Hydrochlorothiazide.
It is recommended to take diuretics in short courses. Short-term use is due to the fact that this drug group, although it cannot provoke cough syndrome, often leads to an imbalance of water and salt indicators, which is manifested by such symptoms as nausea, weakness, dizziness, decreased blood pressure, and cardiac dysfunction.
In addition, potassium-containing drugs, for example, Panangin, are prescribed in parallel with diuretics. This medication regimen helps prevent excessive excretion of potassium from the body, which is typical for diuretics.
To achieve a high effect, it is necessary to combine medications from the above groups.
Combined action medications
- Effectively lowers high blood pressure.
- Suitable for hypertensive patients of different age groups.
- They are easily tolerated, and possible side effects are minimized.
The main difference between these drugs is that they contain medicinal substances from different drug groups. This table shows their effective combinations, which can be recommended to a patient with hypertension if he has a drug-induced cough.
Options | Combination of drugs |
First | Calcium antagonists + ACE inhibitors |
Second | Diuretics + Beta blockers |
Third | Diuretics + ACE inhibitors |
Fourth | Calcium channel blockers + Diuretics |
In addition, the pharmacy also offers ready-made combination drugs of the latest developments, which contain at least three active components:
- Equator.
- Tarka.
- Coaprovel.
- Phosicard N.
- Logimax.
- Atakand Plus.
- Mikardis Plus.
- Korenitek.
- Noliprel Fort.
These medications have a prolonged effect, are highly effective, and exhibit minimal negative effects.
Many experts emphasize the high characteristics of the third generation medicine - Physiotensa, which does not exhibit negative complications such as cough, excessive drowsiness and noticeable dry mouth.
When taking any recommended medications, it is important not to forget that there are no absolutely harmless drugs; every medicine can cause side effects to one degree or another. Also, you should not drink them without a doctor’s permission, as this can lead to a sharp deterioration in your health. The advisability of using any medications for hypertension should be checked with a specialist.
Is it necessary to stop taking the medication that causes the syndrome?
After this you need:
- Consult with a specialist who will develop a new dosage of the drug in the direction of reducing it or prescribe another medication.
- Take medicine that can eliminate this complication.
- Try drinking an antitussive drug.
Usually, after adjusting the dosage of the drug taken, the cough no longer appears. However, a reduced dose may not provide adequate antihypertensive therapy. In this case, the doctor prescribes additional antitussives, for example, Ambroxol.
Regarding whether, after stopping the cough reflex, one should continue to take medications that cause a dry cough in the treatment of hypertension, experts believe that their repeated use in order to complete the course can lead to a deterioration in well-being. Therefore, it is better not to take risks, but to immediately switch to another drug.
What to do if you develop a cough
How to treat cough from blood pressure pills, is it necessary to take any other medications besides the recommendations above? In some cases, the doctor may prescribe symptomatic treatment with the following drugs:
- Theophylline.
- Sulindak.
- Baclofen.
- Medicines with iron.
- Sodium chromoglycate.
This approach is relevant only in situations where antihypertensive drugs are well tolerated by the patient, and there is no reason to replace them with others.
Conclusion
The manifestation of a dry cough as a side reaction from tablets to stabilize blood pressure is quite common. This symptom is mainly provoked by medications included in the group of beta blockers and ACE inhibitors.
This phenomenon does not pose a clear threat to human health, but causes some temporary inconvenience, but it should not be ignored; it must be treated.
It is better to notify a doctor about this, who will select the best option for a medicine that does not cause a cough, because the pharmacy has a sufficient list of effective drugs for hypertension that are not capable of provoking this symptom.
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Source: https://pro-davlenie.ru/simptomy/kashel-pri-prieme-tabletok-ot-davleniya
Blood pressure tablets that do not cause dry cough: 5 best - kardiobit.ru
Hypertension requires an individual approach to the prescription of medications for high blood pressure.
It is very important to select for the patient those medications that will effectively help eliminate the underlying problem, and at the same time will not provoke new health problems.
Unfortunately, many effective blood pressure medications have a serious side effect - they cause coughing. Taking this into account, doctors try to make do with other medications and prescribe blood pressure pills that do not cause coughing.
Features of the treatment of hypertension
Hypertension is by no means a problem for older people. As is known, signs of hypertension have recently begun to be increasingly recorded in young patients. The first stage of hypertension is characterized by an increase of 20/10 units, the second stage is a pressure above 180 to 100, and the third stage goes beyond 200/115.
Doctors warn that therapy must be started already at the first stage, when pressure readings have just exceeded the permissible limits.
When using medications that provoke coughing after taking pills, patients often quit treatment because suffering from coughing brings them significant discomfort. At the same time, imaginary improvements in blood pressure lead patients to the false conclusion that hypertension has been defeated.
This is by no means true, because increased pressure can be disguised as other symptoms that patients cannot distinguish, which means that the problem itself has not been eliminated.
Why does a cough appear and what to do?
A dry cough is a common complication of taking medications to lower blood pressure.
This side effect is most pronounced in ACE inhibitors, so very often patients who enthusiastically began treatment are disappointed in the medications and are forced to stop using them.
An interesting fact is that cough most often occurs in those patients who have developed heart failure against the background of an existing pathology. Complications occur with the use of all drugs from this group, but Captopril and Enalapril are most difficult for patients to tolerate.
Causes of cough
The appearance of cough is primarily provoked by an increase in the specific indicator of bradykinin from the group of peptides, which accumulates in the respiratory tract. Doctors have assumptions that patients have a predisposition to bradykinin deposition, which is why they develop a dry cough as a side effect of therapy with antihypertensive drugs.
After taking medications, irritation of the back of the throat occurs, which provokes a side effect. It is especially aggravated in the lying position.
Eliminating cough from pills
What to do if the drug provokes obvious problems with breathing and coughing? In this case, doctors recommend that patients postpone taking heart medications for at least five days.
This will help restore the airways, and the cough will go away on its own.
Since returning to the drug again can worsen the situation, doctors recommend not to experiment, but to immediately contact them to change the drug.
For some, for example, it will be enough to reduce the dosage and the unpleasant symptoms of cough will go away, as if it never happened. Sometimes doctors prescribe symptomatic therapy, such as Sulindac, which can eliminate cough in such patients. This is done if the antihypertensive drug has a good effect and the doctor would not want to change it for the patient.
Drugs for the treatment of hypertension
There are several groups of drugs that help normalize blood pressure. Based on the indications and side effects, doctors choose the most suitable medications for patients, and some of them can actually provoke a cough.
Beta blockers
Attention! In first place in terms of popularity of prescriptions is the group of beta blockers.
These drugs can quickly lower blood pressure, they reduce the heart rate, but at the same time, long-term use of drugs leads to a dry cough, an allergic reaction, and a slowing of the pulse. The group of drugs is represented by the medications Bisoprolol, Atenolol, Nebivolol and others.
ACE inhibitors can also dilate blood vessels and cope with coronary artery disease and heart failure, but a significant defect of the drugs is a dry cough.
Angiotensin receptor blockers
Among the drugs for high blood pressure, it is worth noting a group of angiotensin receptor blockers. These are angiotensin antagonist drugs that perfectly control blood pressure, lower it evenly, not abruptly, and at the same time they do not provoke a cough. This group of drugs includes Losartan, Cardosal, Eprosartan, Telmisartan, Valsartan.
These drugs perfectly control blood pressure - it is enough to take one tablet a day so that the pressure does not rise all day, and the person feels good. At the same time, to achieve a lasting effect, it is necessary to take the drugs for at least three months.
Calcium channel blockers
A popular group of calcium channel blockers works by reducing calcium levels in muscles. At the same time, the muscles of the heart muscle relax, the pressure decreases, but the most important effect of the drugs is that they do not have such side effects as a dry cough.
If there is not enough calcium in the muscle tissue, then it will not contract much, and therefore, if there is a calcium deficiency in the vessels, they also contract less and do not provoke an increase in pressure. Such drugs include Diltiazem, Amlodipine, Verapramil.
Diuretics
Important! You can also lower your blood pressure with the help of diuretics - they have a diuretic effect and, when removing excess water, do an excellent job of reducing blood pressure. Patients note the positive effect of these drugs and, according to patient reviews, the drugs Triampur, Hydrochlorothiazide, Veroshpiron, Indapamide, Diuver do not cause cough in hypertensive patients.
Doctors note that very often patients exceed the dosage of the drug when used. Frightened by high blood pressure numbers, they take more pills than they should, so for many of them the pills actually provoke a cough. Therefore, doctors emphasize that when taking drugs, overdose options should be excluded.
Choosing a safe product
Hypertensive patients note that when taking several drugs at the same time, side effects increase significantly. However, do not forget that the appearance of a cough can be not only a side effect of tablets, but also a sign of the development of heart failure.
Requirements for choosing a drug
Therefore, when a cough appears, you must first consult a doctor, and only then the doctor will decide whether to change the drug. Drugs selected for the patient must meet three requirements:
- minimum of adverse reactions when taken,
- Possibility of long-term use while maintaining high effectiveness of the product.
Choices
Since groups of drugs that lower blood pressure are not so numerous, doctors choose drugs from three main groups:
- Angiotensin antagonists.
- Calcium antagonists
- Diuretic drugs.
Cardiologists note that dry cough from tablets is provoked by drugs from the group of ACE inhibitors, the enalapril line - Enalapril, Ramipril, Perindopril.
In this case, it is recommended to replace enalapril with an angiotensin antagonist, beta blocker or diuretic, calcium channel blocker.
Various combinations can be made with these drugs that will meet all the basic requirements for treating patients.
Destination Features
When prescribing drugs, it is worth considering that each patient has individual characteristics, each person has his own set of antigens and enzymes that tolerate or do not tolerate a particular drug.
For such people, diuretic drugs have their own characteristics; in addition to lowering blood pressure, they help remove potassium and sodium from the body, which negatively affects the functioning of the heart, causes nausea and dizziness, causes malaise and an excessive drop in blood pressure. Therefore, doctors prefer to use such means as a last resort.
Finding the optimal solution
The choice of doctors falls on Triamterene - a medicine that can lower blood pressure, but at the same time maintain calcium levels in the body. New medications must be used extremely responsibly, because an overdose leads to the accumulation of drugs in the blood, which causes complications in patients.
As for beta blockers, they provoke depression, insomnia, and heart pain in patients. ACE inhibitors, in turn, also provoke a cough, and also affect the appearance of skin rashes and allergic reactions.
A drug such as Lisinopril, in addition to a dry cough, can also cause a lot of other problems with the digestive, nervous and respiratory systems.
It is not surprising that drugs with such side effects are inexpensive.
Patients suffering from hypertension today have many options to use blood pressure pills that do not cause coughing. If this complication occurs, you just need to consult a doctor, and he will select the right medicine.
Side effects of blood pressure medications Which blood pressure pills are the best? Side effects and contraindications of hypertension pills
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Source: https://KardioBit.ru/bolezni-serdtsa/davlenie-i-puls/kakie-tabletki-ot-davleniya-ne-vyzyvayut-kashel
Blood pressure tablets that do not cause coughing: a review of drugs
One of the side effects of some tableted antihypertensive drugs is the ability to provoke the development of a persistent cough reflex. At the same time, modern pharmacology offers a wide range of antihypertensive drugs, from which you can choose blood pressure tablets that do not cause a dry chronic cough.
Cough as a side effect of taking antihypertensive drugs
Unproductive paroxysmal cough with systematic use of antihypertensive tablets is a common phenomenon. It does not appear immediately, but approximately three months after the start of treatment.
Statistics show that during treatment with drugs that lower blood pressure, a cough reflex develops in 15% of patients.
The cough is not accompanied by sputum production, may intensify when changing position, after physical activity, is intrusive, intermittent, and occurs regardless of the time of day.
The pathology is associated with irritation of the back wall of the pharynx; patients describe this condition as an uncomfortable “tickling in the throat.” What is characteristic is that with such a cough there are no signs of bronchial obstruction, there is no pain in the chest.
The likelihood of coughing when taking pills for high blood pressure is determined by:
It is believed that such a cough is harmless to the body. However, it is capable of fairly exhausting the patient before the cause of its development is found. Considering the fact that the cough reflex does not appear immediately after starting to take antihypertensive medications, a person considers many erroneous versions of its origin - from an ordinary cold to serious lung diseases.
Antihypertensive drugs that cause cough
Blood pressure pills can cause chronic cough; this complication is typical for drugs from the group of angiotensin-converting enzyme inhibitors (ACE inhibitors). These drugs have proven to be highly effective, thanks to which they occupy one of the leading places in terms of frequency of prescription in the treatment of hypertension and chronic heart failure.
The action of ACE inhibitors is based on the ability to inhibit the activity of the enzyme that converts inactive angiotensin I into the active hormone angiotensin II. The latter has a pronounced vasoconstrictor property and, after release into the blood, rapidly increases blood pressure. ACE inhibitors prevent this increase and have cardioprotective, angioprotective, and antiatherosclerotic effects.
Cough while taking ACE inhibitors occurs as a result of excessive accumulation of bradykinin (a vasodilator peptide with a hypotensive effect) in the respiratory tract.
Among the representatives of the IACE pharmaceutical group:
- captopril (Capoten, Captopril-AKOS, Captopril Sandoz);
- enalapril (Berlipril, Renipril, Enalapril Hexal, Enap, Ednit);
- lisinopril (Lisinoton, Irumed, Lisinopril Organica, Diroton);
- perindopril (Perindopril-Richter, Perineva, Parnavel, Prestarium);
- ramipril (Hartil, Pyramil, Amprilan);
- fosinopril (Fosicard, Monopril);
- zofenopril (Zocardis).
It has been noted that not all ACE inhibitors have this side effect to the same extent. Most often, cough syndrome develops when taking the drugs enalapril and captopril, less often - fosinopril and perindopril.
Ways to solve the problem
Options for what to do if you develop a cough after taking medications for high blood pressure:
- Reduce the dose of the active substance. In some patients, after this measure, the manifestations of the cough reflex actually decrease, but at the same time there is an insufficient therapeutic effect of the drug.
- Change medicine. The selection of antihypertensive drugs is carried out individually, based on gender, age, weight, and concomitant diseases. The doctor will help you choose a medication from another pharmacological group that does not have the property of causing a cough, for example sartans.
- Continue taking the drug, but use antitussives at the same time. A dubious option, however, is sometimes the only way out of the current situation.
Which blood pressure pills do not cause coughing: choosing the optimal remedy
In addition to ACE inhibitors, there are four more groups of drugs for long-term (basic) treatment of hypertension:
They have completely different mechanisms of action, as well as effectiveness, and, as a rule, are combined with each other or with ACE inhibitors.
Calcium channel blockers
Calcium antagonists are considered as an optimal replacement for ACE inhibitors. Drugs from this pharmaceutical group are well tolerated, do not cause coughing, and have a pronounced hypotensive effect.
BCCs inhibit the penetration of calcium compounds into myocardial and vascular tissues, thereby achieving a pronounced vasodilator effect, starting from the main arteries and ending with peripheral arterioles and precapillaries. Calcium antagonists:
- reduce blood pressure;
- produce anti-ischemic, cardio- and nephroprotective effects;
- minimize the risk of thrombosis;
- prevent atherosclerotic changes in blood vessels;
- improve blood flow in the coronary arteries;
- reduce the need for oxygen in the heart muscle.
List of drugs for high blood pressure that do not cause coughing, from the group of calcium channel blockers:
- amplodipine (Amlotop, Normodipin, Amlovas, Amplodipine Sandoz);
- verapamil (Verapamil-Lect, Isoptin, Finoptin);
- diltiazem (Diltiazem Lannacher, Cardil, Diltsem);
- lercanidipine (Zanidip, Lercanidipine-C3, Lernicor);
- nifedipine (Corinfar, Cordipin, Adalat, Cordaflex);
- felodipine (Felodip, Plendil, Felodipine-C3).
Calcium antagonists are recommended for elderly people with diabetes, hypercholesterolemia, and atherosclerosis.
Beta blockers
It is advisable to prescribe beta-blockers for arterial hypertension, arrhythmia, and for the prevention of recurrent myocardial infarction. Active against beta-adrenergic receptors, blocking which contributes to the onset of cardiac effects:
- slow heart rate;
- decrease in the force of myocardial contractions;
- decreased oxygen consumption by the heart muscle;
- depression of cardiac conduction.
The list of antihypertensive beta-blockers includes:
- bisoprolol (Concor, Cordinorm, Biprol, Aritel, Coronal);
- metoprolol (Metocard, Egilok, Betalok, Serdol);
- nebivolol (Nebilet, Nebilong, Nebivolol Sandoz, Binelol);
- propranolol (Anaprilin, Inderal, Obzidan);
- atenolol (Atenolol Belupo, Betacard, Atenolol Nycomed).
Non-selective beta-blockers do not cause coughing or cause it in isolated cases; however, they have a number of side effects, the most important of which is a marked decrease in libido and sexual performance in both men and women. Selective beta-blockers do not have this property.
Thiazide diuretics
Diuretics do not cause a cough reflex, but at the same time they are not recommended for monotherapy of hypertension. It is more advisable to include small doses of diuretics in combination antihypertensive drugs. Most often they are combined with calcium antagonists and/or ACE inhibitors.
Diuretics inhibit the absorption of sodium ions in the kidney tubules, thereby reducing the volume of fluid in tissues and cavities through increased urine excretion. A smooth decrease in blood pressure levels is explained by a decrease in circulating blood volumes.
Among the representatives of the group of diuretics with antihypertensive properties:
- indapamide (Indap, Revel);
- hydrochlorothiazide (Hypothiazide);
- spironolactone (Veroshpiron, Veroshpilakton);
- torsemide (Diuver, Britomar);
- furosemide (Lasix).
When treated with some diuretic drugs, additional potassium intake is required.
Combination drugs
Many patients with severe arterial hypertension require two or more antihypertensive medications to keep their blood pressure within normal limits.
Today, this problem is solved with the help of combination drugs, which successfully combine the properties of several antihypertensive components, the negative effect of one of which is suppressed by the positive effect of the other. The following are most often combined in one drug:
- CCBs with ACE inhibitors;
- diuretics with beta-blockers;
- diuretics with ACE inhibitors;
- CCB with diuretics;
- ACE inhibitors with CCBs and diuretics.
Which combination drugs for high blood pressure do not cause coughing? Among the most popular: Ko-Renitek, Ko-Dalneva, Equator, Egipres, Prestilol, Iruzid, Tarka, Logimax, Fosicard N, Berlipril Plus, Enap NL, Prestance, Niperten Combi. Due to the small concentration of several active ingredients, they do not cause a cough reflex or do so very rarely, have a prolonged effect, and have virtually no side effects.
- review of combination drugs for blood pressure and hypertension
- Thus, if an obsessive cough develops as a reaction to taking ACE inhibitors, the optimal replacement is drugs from the group of calcium channel blockers or combination drugs.
Last updated: October 8, 2019
Source: https://sosudy.info/tabletki-ot-davleniya-ne-vyzyvayushhie-kashel
Blood pressure medications that do not cause coughing: what to do when taking them
Drug treatment of hypertension is necessary, as this will normalize blood pressure and prevent the development of a number of complications, such as heart attack and stroke.
However, medications for hypertension can only be taken after a doctor's prescription. After all, there are different groups of drugs that have different effects and have a number of side effects, such as dizziness, increased urination, cough, etc.
It is impossible to do without drug therapy, because high blood pressure has a slow destructive effect on the entire body. But most often the kidneys, heart and brain are affected by hypertension.
What should you do to prevent the development of complications? Antihypertensive medications should be taken regularly, because this is the only way to control blood pressure.
All drugs for high blood pressure are divided into groups. They can be used as monotherapy or combined with each other to enhance the effect and reduce side effects.
Types of blood pressure medications
Diuretics. Diuretic medications can quickly reduce blood pressure by removing salts and excess fluid from the body. To quickly normalize blood pressure, the use of potassium-sparing diuretics and saluretics (Dicarb, Hypothiazide, Furosemide and others) is recommended.
These diuretic drugs remove not only water from the body, but also calcium and sodium salts. However, a deficiency of potassium salts negatively affects the functioning of muscles, including the myocardium.
But what to do if you need to lower your blood pressure? For these reasons, along with saluretics, you should take drugs containing potassium salts - Asparkam or Panangin.
Potassium-sparing diuretics for hypertension, such as Triamterene, do not remove potassium. But if they are used incorrectly, they can accumulate in the blood, which also has an adverse effect on the body.
It is worth noting that diuretics do not cause a cough, but they can provoke a disorder of water-salt balance, resulting in such side effects as:
- nausea
- dizziness;
- malaise;
- heart problems;
- decrease in pressure and so on.
Popular diuretics are Hydrochlorothiazide, Spironolactone, Indapamide, Triampur, Diuver and others.
Beta blockers. Used to lower high blood pressure that occurs due to heart problems, such as coronary artery disease. The drugs affect the cardiovascular system of adrenaline, they block the beta receptors of adrenaline, which is sensitive to this substance.
At the same time, the vessels, including the coronary ones, dilate, as a result of which the heart rate normalizes and pressure indicators decrease. As a rule, beta-blockers such as Bisoprolol, Metoprolol, Celiprolol are prescribed to young patients with heart problems.
Due to the narrowing of peripheral blood vessels, beta blockers should not be taken by patients with poor circulation in the extremities.
In this case, it is recommended to use alpha-blockers that act on alpha-adrenergic receptors, which are responsible for the contraction of small peripheral arterioles. These include:
- Alfuzosin;
- Tropaphen;
- Terazosin;
- Phentolamine;
- Doxazosin;
- Phenoxybenzamine;
- Prazosin;
- Pyrroxane.
Calcium channel blockers. In addition to lowering blood pressure, such medications are used for heart diseases. CCBs block the flow of calcium into muscle cells, inhibiting their contraction.
With a lack of calcium, the smooth muscles of the walls of blood vessels do not contract as necessary. As a result, the vessels relax, blood flow inside them is facilitated and pressure decreases.
Prominent representatives of BCC are the following drugs:
- Diltiazem;
- Verapramil;
- Amlodipine.
ACE inhibitors. These pills dilate blood vessels. ACE is an enzyme involved in the synthesis of a substance that has a strong vasoconstrictor effect - angiotensin II.
Basically, ACE inhibitors are indicated for hypertension that develops against the background of heart and kidney diseases. Also, drugs belonging to this group are indicated for high diastolic pressure and in case of increased load on the heart muscle.
However, with regular use of ACE inhibitors, a dry cough appears. What to do in this case? Often, the doctor prescribes antihypertensive drugs belonging to a different group.
Popular drugs from this group are Ramipril, Perindopril, Enalapril.
Angiotensin II receptor blockers. These drugs monitor blood pressure for 24 hours. However, in order to achieve a sustainable decrease in blood pressure, you need to drink them for at least 3 months.
It is noteworthy that angiotensin 2 receptor blockers have virtually no side effects, including that they do not cause coughing.
Centrally acting agents. Popular representatives of this drug group are Moxonidine, Methyldopa and Albarel. Such drugs bind to receptors in nerve cells, regulating the activity of the SNS and reducing the intensity of vasoconstrictor signals. As a result, vascular spasm is eliminated, and pressure numbers drop.
It is worth noting that centrally acting tablets of the previous generation (Clonidine) are now practically not used in the treatment of hypertension.
What blood pressure medications cause coughing?
Most often, a dry cough develops after taking ACE inhibitors. As a rule, it is precisely this side effect that forces treatment to be discontinued.
It is worth noting that cough can occur as a result of therapy with any medications from this group. But most often, such a negative symptom develops during treatment with Enalapril and Captopril. Moreover, cough occurs twice as often after taking Enalapril.
It is worth noting that after taking ACE inhibitors in patients with CHF, this side effect appears much more often than in hypertensive patients (26% and 15%). The reasons for its occurrence include an increase in the concentration of bradykinin, which collects in the upper respiratory tract, causing cough.
In addition, a hereditary predisposition to the development of cough after taking ACE inhibitors is assumed. In this case, the patient feels an unpleasant tickling in the back wall of the throat.
Basically, the cough is paroxysmal, dry, prolonged and intermittent. It often gets worse when the patient is lying down, which can lead to hoarseness and even urinary incontinence and vomiting.
Moreover, these phenomena are not accompanied by hypersensitivity, symptoms of bronchial obstruction or changes in kidney function. What to do to eliminate cough after taking ACEI? According to some studies, to eliminate cough it is enough to reduce the dosage of the drug.
The time from the start of therapy with ACE inhibitors until the onset of an unpleasant symptom can range from 1 day to 1 year. But on average it appears 14.5 weeks after regular use of the drug.
It is worth noting that the cough reflex that develops while taking ACE inhibitors is generally not dangerous to the patient’s health; it often simply causes discomfort. But it was found that patients with this symptom have a worse quality of life and are more susceptible to depression.
To determine whether the cough is caused by the use of ACE inhibitors, their use must be discontinued for 4 days. Typically, the symptom disappears after 1-14 days. But if treatment is resumed, it may develop again.
What to do and what medications can be used to suppress the cough reflex after taking ACE inhibitors? The following medications are used to relieve cough:
- Sodium chromoglycate;
- Baclofen;
- Theophylline;
- Sulindak;
- Iron supplements.
In addition to ACE inhibitors, cough can develop against the background of lowering blood pressure with beta blockers. Such drugs affect sensitive receptors located in the blood vessels, heart and bronchi.
When the blood vessels narrow, a dry, unproductive cough appears. It can also occur during physical activity and changes in body position.
What medications are safest to use for hypertension?
Today, calcium channel blockers are increasingly used in the treatment of hypertension. They have a specific effect on organs and a minimal number of adverse reactions.
New tablets from this group can bind to calcium channels in cell membranes located in the vascular walls and myocardium.
When calcium enters a cell, the following happens:
- increased excitability and conductivity;
- activation of metabolic processes;
- muscle contraction;
- increased oxygen consumption.
However, some modern tablets from this group infringe on such processes. These include the following drugs:
- Isradipin;
- Amlodipine;
- Lacidipine;
- Nimodipine;
- Felodipine;
- Nisoldipine;
- Nicardipine;
- Nitrendipine;
- Riodipine.
Calcium channel blockers have a number of advantages. So, in addition to lowering blood pressure, they improve the general well-being of hypertensive patients and are well tolerated in old age. And modern CCBs reduce hypertrophy in the left ventricle and do not suppress physical and mental activity.
In addition, calcium channel blockers do not cause depression and do not increase bronchial tone, which cannot be said about adrenergic blockers. Therefore, such medications are recommended if hypertension is combined with broncho-obstructive diseases.
Also, CCBs improve the excretory function of the kidneys and have a positive effect on the carbohydrate metabolism of uric acid and lipids. Thanks to this property, they are superior to thiazide diuretics and adrenergic blockers.
In addition to CCBs, diuretics are increasingly used for hypertension, which remove salts and fluid from the body, reducing blood volume, thereby lowering blood pressure. Modern safe diuretics are:
- Spironolactone;
- Metolazone;
- Triamterene;
- Indapamide;
- Hydrochlorothiazide;
- Chlorthalidone;
- Furosemide.
Also, in case of hypertension, it is customary to combine antihypertensive drugs to enhance the effect and reduce adverse reactions, including cough.
It is worth noting that with the right combination, some drugs neutralize each other's side effects. Therefore, every patient suffering from high blood pressure should know the combination of drugs used in the treatment of arterial hypertension.
During treatment with combination drugs, the incidence of hypertensive complications is significantly reduced. Often 2 or 3 agents are combined. The most effective combinations of 2 drugs are:
- ACE inhibitor + diuretic;
- Calcium antagonist + receptor blocker;
- Receptor blocker + diuretic;
- Calcium antagonist + ACE inhibitor;
- Calcium antagonist + diuretic.
Such combinations are the optimal solution for the treatment of hypertension. Effective combinations of three drugs are:
- ACEI + AKD + BB;
- ADC + BB + diuretic;
- ARB + AKD + BB;
- BB + ARB + diuretic;
- ACEI + AA + diuretic;
- BB + diuretic + ACEI;
- ARB + AA + diuretic.
In addition, there are combination drugs that combine two active ingredients in one tablet. These include Enzix duo forte (enalapril and indapamide), Lodoz, Aritel plus (hydrochlorothiazide and bisoprolol), Co-diovan (hydrochlorothiazide and valsartan) and Logimax (metoprolol and felodipine).
Also popular combination drugs are Gizaar, Lorista N/ND, Lozap plus (hydrochlorothiazide and losartan), Exforge (amlodipine and valsartan), Atacand plus (hydrochlorothiazide and candesartan) and Tarka (verapamil and trandolapril).
However, there are no absolutely safe drugs that do not cause any adverse reactions. But there are modern antihypertensive drugs that have a number of advantages over other drugs. This allows them to have a minimum number of adverse reactions, because new components make such tablets less dangerous.
Some of the best modern antihypertensive drugs are selective imidazoline receptor agonists. Such drugs rarely provoke the appearance of adverse reactions, quickly normalize blood pressure and have practically no contraindications. Popular drugs from this group are Monoxidine or Rilmenidine.
In addition, it is worth choosing drugs that have a rapid effect and a prolonged effect, which allows you to minimize the risk of adverse reactions. Therefore, it is preferable to choose complex drugs that have virtually no side effects, which makes them the optimal choice in the fight against hypertension.
One of the safest third-generation drugs is Physiotens. After taking it, there is practically no increased drowsiness, cough or dryness of the oral mucosa.
This is a new remedy for high blood pressure without side effects and does not have an adverse effect on respiratory function, so Physiotens can be taken even with bronchial asthma.
In addition, the medicine increases insulin sensitivity, which is important for insulin-dependent patients suffering from diabetes.
The patients themselves will tell you in detail about the types of tablets in the video in this article.
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Source: https://gipertonija.ru/medicamenty/tabletki-ot-davleniya-ne-vyzyvayushhie-kashel.html
New drugs for hypertension that do not cause coughing - no hypertension
For the prevention and treatment of the cardiovascular system, medications in the form of tablets are often used.
These drugs are used for a fairly long period; it is important that the drug is well tolerated. One of the most common consequences is coughing when taking blood pressure pills.
What is the reason for this phenomenon and how to choose a remedy for pressure without additional side effects on the body?
Why does a cough appear?
Drug therapy is mandatory for hypertension. Doctors select treatment for each patient individually, taking into account the perception of the drug, individual characteristics, age, and lifestyle of the patient.
Coughing occurs often when taking blood pressure medications, but not always. There are a number of drugs that provoke a dry cough:
- After taking ACE inhibitors, a cough occurs several months or even weeks after the start of therapy. The drugs Captopril and Enalapril especially have such side effects on the body.
- The appearance of a cough can also occur when taking adrenergic blockers; the reason for this is the accumulation of the bradykinin peptide in the upper respiratory tract.
Cough from blood pressure pills is safe, but there is a feeling of discomfort. It intensifies in a horizontal position of the body and during active physical activity.
If cough syndrome occurs, be sure to consult a doctor for advice.
One of the side effects after taking antihypertensive drugs is cough.
Eliminating cough from pills
There are several ways to eliminate dry cough from pills:
- reduce the dosage of the drug;
- replace with another product;
- administer medications that eliminate complications;
- take antitussives.
Do not try to carry out such therapeutic measures yourself; a sudden switch or withdrawal of medication provokes pressure surges and complications of the disease.
Which blood pressure pills do not cause coughing?
Modern medicine is developing, so new blood pressure pills are appearing that do not cause coughing. They can be divided into:
- angiotensin receptor blockers;
- calcium antagonists;
- diuretics.
When choosing a medication for blood pressure, it is better to choose drugs with a mild effect that do not provoke a dry cough, and ACE inhibitors and adrenergic blockers should be prescribed with caution. Let's take a closer look at which blood pressure medications do not cause coughing?
Hypertension drugs have a strict classification, which depends on the mechanism of action
Calcium antagonists
Belongs to the group of calcium channel blockers. Tablets based on them do not cause coughing attacks. They block the flow of calcium into muscle cells, which serves as an opportunity to relax the walls of blood vessels.
The drugs act only on myocardial and vascular cells, they:
- conduct impulses better;
- normalize the process of increasing excitability;
- equalize the pressure to the operating indicators and stabilize it;
- normalize carbohydrate metabolism;
- increase the activity of the heart muscles.
The most effective drugs of the group:
- "Nicardipine";
- "Nimodipine."
These drugs have virtually no unpleasant consequences, so they are used to treat older people and patients with diabetes.
Diuretics lower blood pressure by removing excess fluid, and not only do not cause a cough, but also reduce the likelihood of excess fluid accumulating in the lungs
Diuretics
What are diuretics in the treatment of hypertension? These are blood pressure medications that do not cause coughing, have a diuretic property, remove excess fluid and salts from the body, which allows you to normalize blood pressure by reducing the amount of blood in the vessels.
Diuretics are prescribed in small courses. When using such drugs, the presence of potassium in other drugs must be taken into account when used simultaneously.
Diuretics are recommended to be taken with ACE inhibitors and calcium blockers. The most popular:
- "Furosemide";
- "Arifon";
- "Triampur".
Combination medications
Modern cardiologists are switching to combination drugs. They are intended for the treatment of hypertension and can consist of two or three active ingredients. The most popular combinations: calcium blockers and ACE inhibitors, as well as diuretics in combination with adrenergic blockers, ACE inhibitors, calcium blockers.
Such combinations are easier to tolerate by patients, and the drugs complement each other and do not provoke the development of a dry cough. Therefore, combination drugs for the treatment of hypertension have virtually no side effects, work gently, and the effect lasts longer.
These are drugs that have a unique effect on the course of treatment, but at the same time cause a minimum of side symptoms.
Effective drugs in this group:
- "Equator";
- Logimax;
- "Atakand Plus".
Choosing a safe product
The selection of complex treatment can combine medications and folk remedies for hypertension. You can find many traditional medicine recipes that are used to treat and prevent vascular and heart diseases.
The choice of additional treatments must be agreed with your doctor. Perhaps he will advise which fruits, berries, and herbs will be most effective for hypertension.
Requirements for choosing a drug
All medications have their contraindications and side effects, so try to make your choice according to the rules, namely:
- the drug must contain a minimum number of contraindications and maximum therapeutic effect;
- the effect of the drug should be mild and last as long as possible;
- the drug should not have a bad effect on other organs.
Before using the drug, be sure to read the instructions for use. Poor tolerance to any medication is a reason to visit a doctor.
Destination Features
All medications are prescribed by a doctor after undergoing diagnostics. Treatment takes into account:
- patient's age;
- Lifestyle;
- chronic diseases;
- bad habits;
- physical exercise.
Selection of treatment is a lengthy process; it is possible to replace one remedy with another. The reason may be intolerance to the drug, poor results, side effects, including dry cough.
Finding the optimal solution
Selecting the optimal blood pressure remedy is the main issue for solving the problem. Every patient wants to receive a medicine that acts quickly, with minimal side effects. However, the final choice always remains with the attending physician.
Source: https://gipertensianet.ru/novye-lekarstva-ot-gipertonii-ne-vyzyvayushhie-kashel.html